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This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range of downstream tasks, as they can help to accelerate the development of accurate and robust models, reduce the large amounts of required labeled data, preserve the privacy and confidentiality of patient data. Specifically, we illustrate the "spectrum" of medical foundation models, ranging from general vision models, modality-specific models, to organ/task-specific models, highlighting their challenges, opportunities and applications. We also discuss how foundation models can be leveraged in downstream medical tasks to enhance the accuracy and efficiency of medical image analysis, leading to more precise diagnosis and treatment decisions.

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ACM/IEEE第23屆模型驅動工程語言和系統國際會議,是模型驅動軟件和系統工程的首要會議系列,由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來,模型涵蓋了建模的各個方面,從語言和方法到工具和應用程序。模特的參加者來自不同的背景,包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇,參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會,并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。 官網鏈接: · 評論員 · Analysis · 判別器 · 原點 ·
2023 年 8 月 1 日

In recent years large model trained on huge amount of cross-modality data, which is usually be termed as foundation model, achieves conspicuous accomplishment in many fields, such as image recognition and generation. Though achieving great success in their original application case, it is still unclear whether those foundation models can be applied to other different downstream tasks. In this paper, we conduct a short survey on the current methods for discriminative dense recognition tasks, which are built on the pretrained foundation model. And we also provide some preliminary experimental analysis of an existing open-vocabulary segmentation method based on Stable Diffusion, which indicates the current way of deploying diffusion model for segmentation is not optimal. This aims to provide insights for future research on adopting foundation model for downstream task.

The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has been dramatically improved, leading to human-like performances in understanding, language synthesizing, and common-sense reasoning, etc. Such a major leap-forward in general AI capacity will change the pattern of how personalization is conducted. For one thing, it will reform the way of interaction between humans and personalization systems. Instead of being a passive medium of information filtering, large language models present the foundation for active user engagement. On top of such a new foundation, user requests can be proactively explored, and user's required information can be delivered in a natural and explainable way. For another thing, it will also considerably expand the scope of personalization, making it grow from the sole function of collecting personalized information to the compound function of providing personalized services. By leveraging large language models as general-purpose interface, the personalization systems may compile user requests into plans, calls the functions of external tools to execute the plans, and integrate the tools' outputs to complete the end-to-end personalization tasks. Today, large language models are still being developed, whereas the application in personalization is largely unexplored. Therefore, we consider it to be the right time to review the challenges in personalization and the opportunities to address them with LLMs. In particular, we dedicate this perspective paper to the discussion of the following aspects: the development and challenges for the existing personalization system, the newly emerged capabilities of large language models, and the potential ways of making use of large language models for personalization.

Foundation models pretrained on diverse data at scale have demonstrated extraordinary capabilities in a wide range of vision and language tasks. When such models are deployed in real world environments, they inevitably interface with other entities and agents. For example, language models are often used to interact with human beings through dialogue, and visual perception models are used to autonomously navigate neighborhood streets. In response to these developments, new paradigms are emerging for training foundation models to interact with other agents and perform long-term reasoning. These paradigms leverage the existence of ever-larger datasets curated for multimodal, multitask, and generalist interaction. Research at the intersection of foundation models and decision making holds tremendous promise for creating powerful new systems that can interact effectively across a diverse range of applications such as dialogue, autonomous driving, healthcare, education, and robotics. In this manuscript, we examine the scope of foundation models for decision making, and provide conceptual tools and technical background for understanding the problem space and exploring new research directions. We review recent approaches that ground foundation models in practical decision making applications through a variety of methods such as prompting, conditional generative modeling, planning, optimal control, and reinforcement learning, and discuss common challenges and open problems in the field.

Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from using traditional methods to infer potential causal structures from observational data to the field of pattern recognition involved in deep learning. The rapid accumulation of massive data promotes the emergence of causal search methods with brilliant scalability. Existing summaries of causal discovery methods mainly focus on traditional methods based on constraints, scores and FCMs, there is a lack of perfect sorting and elaboration for deep learning-based methods, also lacking some considers and exploration of causal discovery methods from the perspective of variable paradigms. Therefore, we divide the possible causal discovery tasks into three types according to the variable paradigm and give the definitions of the three tasks respectively, define and instantiate the relevant datasets for each task and the final causal model constructed at the same time, then reviews the main existing causal discovery methods for different tasks. Finally, we propose some roadmaps from different perspectives for the current research gaps in the field of causal discovery and point out future research directions.

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.

Image registration is a critical component in the applications of various medical image analyses. In recent years, there has been a tremendous surge in the development of deep learning (DL)-based medical image registration models. This paper provides a comprehensive review of medical image registration. Firstly, a discussion is provided for supervised registration categories, for example, fully supervised, dual supervised, and weakly supervised registration. Next, similarity-based as well as generative adversarial network (GAN)-based registration are presented as part of unsupervised registration. Deep iterative registration is then described with emphasis on deep similarity-based and reinforcement learning-based registration. Moreover, the application areas of medical image registration are reviewed. This review focuses on monomodal and multimodal registration and associated imaging, for instance, X-ray, CT scan, ultrasound, and MRI. The existing challenges are highlighted in this review, where it is shown that a major challenge is the absence of a training dataset with known transformations. Finally, a discussion is provided on the promising future research areas in the field of DL-based medical image registration.

Transformers have dominated the field of natural language processing, and recently impacted the computer vision area. In the field of medical image analysis, Transformers have also been successfully applied to full-stack clinical applications, including image synthesis/reconstruction, registration, segmentation, detection, and diagnosis. Our paper presents both a position paper and a primer, promoting awareness and application of Transformers in the field of medical image analysis. Specifically, we first overview the core concepts of the attention mechanism built into Transformers and other basic components. Second, we give a new taxonomy of various Transformer architectures tailored for medical image applications and discuss their limitations. Within this review, we investigate key challenges revolving around the use of Transformers in different learning paradigms, improving the model efficiency, and their coupling with other techniques. We hope this review can give a comprehensive picture of Transformers to the readers in the field of medical image analysis.

Rishi Bommasani,Drew A. Hudson,Ehsan Adeli,Russ Altman,Simran Arora,Sydney von Arx,Michael S. Bernstein,Jeannette Bohg,Antoine Bosselut,Emma Brunskill,Erik Brynjolfsson,Shyamal Buch,Dallas Card,Rodrigo Castellon,Niladri Chatterji,Annie Chen,Kathleen Creel,Jared Quincy Davis,Dora Demszky,Chris Donahue,Moussa Doumbouya,Esin Durmus,Stefano Ermon,John Etchemendy,Kawin Ethayarajh,Li Fei-Fei,Chelsea Finn,Trevor Gale,Lauren Gillespie,Karan Goel,Noah Goodman,Shelby Grossman,Neel Guha,Tatsunori Hashimoto,Peter Henderson,John Hewitt,Daniel E. Ho,Jenny Hong,Kyle Hsu,Jing Huang,Thomas Icard,Saahil Jain,Dan Jurafsky,Pratyusha Kalluri,Siddharth Karamcheti,Geoff Keeling,Fereshte Khani,Omar Khattab,Pang Wei Kohd,Mark Krass,Ranjay Krishna,Rohith Kuditipudi,Ananya Kumar,Faisal Ladhak,Mina Lee,Tony Lee,Jure Leskovec,Isabelle Levent,Xiang Lisa Li,Xuechen Li,Tengyu Ma,Ali Malik,Christopher D. Manning,Suvir Mirchandani,Eric Mitchell,Zanele Munyikwa,Suraj Nair,Avanika Narayan,Deepak Narayanan,Ben Newman,Allen Nie,Juan Carlos Niebles,Hamed Nilforoshan,Julian Nyarko,Giray Ogut,Laurel Orr,Isabel Papadimitriou,Joon Sung Park,Chris Piech,Eva Portelance,Christopher Potts,Aditi Raghunathan,Rob Reich,Hongyu Ren,Frieda Rong,Yusuf Roohani,Camilo Ruiz,Jack Ryan,Christopher Ré,Dorsa Sadigh,Shiori Sagawa,Keshav Santhanam,Andy Shih,Krishnan Srinivasan,Alex Tamkin,Rohan Taori,Armin W. Thomas,Florian Tramèr,Rose E. Wang,William Wang,Bohan Wu,Jiajun Wu,Yuhuai Wu,Sang Michael Xie,Michihiro Yasunaga,Jiaxuan You,Matei Zaharia,Michael Zhang,Tianyi Zhang,Xikun Zhang,Yuhui Zhang,Lucia Zheng,Kaitlyn Zhou,Percy Liang
Rishi Bommasani,Drew A. Hudson,Ehsan Adeli,Russ Altman,Simran Arora,Sydney von Arx,Michael S. Bernstein,Jeannette Bohg,Antoine Bosselut,Emma Brunskill,Erik Brynjolfsson,Shyamal Buch,Dallas Card,Rodrigo Castellon,Niladri Chatterji,Annie Chen,Kathleen Creel,Jared Quincy Davis,Dora Demszky,Chris Donahue,Moussa Doumbouya,Esin Durmus,Stefano Ermon,John Etchemendy,Kawin Ethayarajh,Li Fei-Fei,Chelsea Finn,Trevor Gale,Lauren Gillespie,Karan Goel,Noah Goodman,Shelby Grossman,Neel Guha,Tatsunori Hashimoto,Peter Henderson,John Hewitt,Daniel E. Ho,Jenny Hong,Kyle Hsu,Jing Huang,Thomas Icard,Saahil Jain,Dan Jurafsky,Pratyusha Kalluri,Siddharth Karamcheti,Geoff Keeling,Fereshte Khani,Omar Khattab,Pang Wei Kohd,Mark Krass,Ranjay Krishna,Rohith Kuditipudi,Ananya Kumar,Faisal Ladhak,Mina Lee,Tony Lee,Jure Leskovec,Isabelle Levent,Xiang Lisa Li,Xuechen Li,Tengyu Ma,Ali Malik,Christopher D. Manning,Suvir Mirchandani,Eric Mitchell,Zanele Munyikwa,Suraj Nair,Avanika Narayan,Deepak Narayanan,Ben Newman,Allen Nie,Juan Carlos Niebles,Hamed Nilforoshan,Julian Nyarko,Giray Ogut,Laurel Orr,Isabel Papadimitriou,Joon Sung Park,Chris Piech,Eva Portelance,Christopher Potts,Aditi Raghunathan,Rob Reich,Hongyu Ren,Frieda Rong,Yusuf Roohani,Camilo Ruiz,Jack Ryan,Christopher Ré,Dorsa Sadigh,Shiori Sagawa,Keshav Santhanam,Andy Shih,Krishnan Srinivasan,Alex Tamkin,Rohan Taori,Armin W. Thomas,Florian Tramèr,Rose E. Wang,William Wang,Bohan Wu,Jiajun Wu,Yuhuai Wu,Sang Michael Xie,Michihiro Yasunaga,Jiaxuan You,Matei Zaharia,Michael Zhang,Tianyi Zhang,Xikun Zhang,Yuhui Zhang,Lucia Zheng,Kaitlyn Zhou,Percy Liang

AI is undergoing a paradigm shift with the rise of models (e.g., BERT, DALL-E, GPT-3) that are trained on broad data at scale and are adaptable to a wide range of downstream tasks. We call these models foundation models to underscore their critically central yet incomplete character. This report provides a thorough account of the opportunities and risks of foundation models, ranging from their capabilities (e.g., language, vision, robotics, reasoning, human interaction) and technical principles(e.g., model architectures, training procedures, data, systems, security, evaluation, theory) to their applications (e.g., law, healthcare, education) and societal impact (e.g., inequity, misuse, economic and environmental impact, legal and ethical considerations). Though foundation models are based on standard deep learning and transfer learning, their scale results in new emergent capabilities,and their effectiveness across so many tasks incentivizes homogenization. Homogenization provides powerful leverage but demands caution, as the defects of the foundation model are inherited by all the adapted models downstream. Despite the impending widespread deployment of foundation models, we currently lack a clear understanding of how they work, when they fail, and what they are even capable of due to their emergent properties. To tackle these questions, we believe much of the critical research on foundation models will require deep interdisciplinary collaboration commensurate with their fundamentally sociotechnical nature.

High spectral dimensionality and the shortage of annotations make hyperspectral image (HSI) classification a challenging problem. Recent studies suggest that convolutional neural networks can learn discriminative spatial features, which play a paramount role in HSI interpretation. However, most of these methods ignore the distinctive spectral-spatial characteristic of hyperspectral data. In addition, a large amount of unlabeled data remains an unexploited gold mine for efficient data use. Therefore, we proposed an integration of generative adversarial networks (GANs) and probabilistic graphical models for HSI classification. Specifically, we used a spectral-spatial generator and a discriminator to identify land cover categories of hyperspectral cubes. Moreover, to take advantage of a large amount of unlabeled data, we adopted a conditional random field to refine the preliminary classification results generated by GANs. Experimental results obtained using two commonly studied datasets demonstrate that the proposed framework achieved encouraging classification accuracy using a small number of data for training.

Inspired by recent development of artificial satellite, remote sensing images have attracted extensive attention. Recently, noticeable progress has been made in scene classification and target detection.However, it is still not clear how to describe the remote sensing image content with accurate and concise sentences. In this paper, we investigate to describe the remote sensing images with accurate and flexible sentences. First, some annotated instructions are presented to better describe the remote sensing images considering the special characteristics of remote sensing images. Second, in order to exhaustively exploit the contents of remote sensing images, a large-scale aerial image data set is constructed for remote sensing image caption. Finally, a comprehensive review is presented on the proposed data set to fully advance the task of remote sensing caption. Extensive experiments on the proposed data set demonstrate that the content of the remote sensing image can be completely described by generating language descriptions. The data set is available at //github.com/2051/RSICD_optimal

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