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Investigators are increasingly using novel methods for extending (generalizing or transporting) causal inferences from a trial to a target population. In many generalizability and transportability analyses, the trial and the observational data from the target population are separately sampled, following a non-nested trial design. In practical implementations of this design, non-randomized individuals from the target population are often identified by conditioning on the use of a particular treatment, while individuals who used other candidate treatments for the same indication or individuals who did not use any treatment are excluded. In this paper, we argue that conditioning on treatment in the target population changes the estimand of generalizability and transportability analyses and potentially introduces serious bias in the estimation of causal estimands in the target population or the subset of the target population using a specific treatment. Furthermore, we argue that the naive application of marginalization-based or weighting-based standardization methods does not produce estimates of any reasonable causal estimand. We use causal graphs and counterfactual arguments to characterize the identification problems induced by conditioning on treatment in the target population and illustrate the problems using simulated data. We conclude by considering the implications of our findings for applied work.

Replay methods have shown to be successful in mitigating catastrophic forgetting in continual learning scenarios despite having limited access to historical data. However, storing historical data is cheap in many real-world applications, yet replaying all historical data would be prohibited due to processing time constraints. In such settings, we propose learning the time to learn for a continual learning system, in which we learn replay schedules over which tasks to replay at different time steps. To demonstrate the importance of learning the time to learn, we first use Monte Carlo tree search to find the proper replay schedule and show that it can outperform fixed scheduling policies in terms of continual learning performance. Moreover, to improve the scheduling efficiency itself, we propose to use reinforcement learning to learn the replay scheduling policies that can generalize to new continual learning scenarios without added computational cost. In our experiments, we show the advantages of learning the time to learn, which brings current continual learning research closer to real-world needs.

Hardware supply-chain attacks are raising significant security threats to the boot process of multiprocessor systems. This paper identifies a new, prevalent hardware supply-chain attack surface that can bypass multiprocessor secure boot due to the absence of processor-authentication mechanisms. To defend against such attacks, we present PA-Boot, the first formally verified processor-authentication protocol for secure boot in multiprocessor systems. PA-Boot is proved functionally correct and is guaranteed to detect multiple adversarial behaviors, e.g., processor replacements, man-in-the-middle attacks, and tampering with certificates. The fine-grained formalization of PA-Boot and its fully mechanized security proofs are carried out in the Isabelle/HOL theorem prover with 306 lemmas/theorems and ~7,100 LoC. Experiments on a proof-of-concept implementation indicate that PA-Boot can effectively identify boot-process attacks with a considerably minor overhead and thereby improve the security of multiprocessor systems.

There is still a significant gap between expectations and the successful adoption of AI to innovate and improve businesses. Due to the emergence of deep learning, AI adoption is more complex as it often incorporates big data and the internet of things, affecting data privacy. Existing frameworks have identified the need to focus on human-centered design, combining technical and business/organizational perspectives. However, trust remains a critical issue that needs to be designed from the beginning. The proposed framework expands from the human-centered design approach, emphasizing and maintaining the trust that underpins the process. This paper proposes a theoretical framework for responsible artificial intelligence (AI) implementation. The proposed framework emphasizes a synergistic business technology approach for the agile co-creation process. The aim is to streamline the adoption process of AI to innovate and improve business by involving all stakeholders throughout the project so that the AI technology is designed, developed, and deployed in conjunction with people and not in isolation. The framework presents a fresh viewpoint on responsible AI implementation based on analytical literature review, conceptual framework design, and practitioners' mediating expertise. The framework emphasizes establishing and maintaining trust throughout the human-centered design and agile development of AI. This human-centered approach is aligned with and enabled by the privacy by design principle. The creators of the technology and the end-users are working together to tailor the AI solution specifically for the business requirements and human characteristics. An illustrative case study on adopting AI for assisting planning in a hospital will demonstrate that the proposed framework applies to real-life applications.

Along with the massive growth of the Internet from the 1990s until now, various innovative technologies have been created to bring users breathtaking experiences with more virtual interactions in cyberspace. Many virtual environments with thousands of services and applications, from social networks to virtual gaming worlds, have been developed with immersive experience and digital transformation, but most are incoherent instead of being integrated into a platform. In this context, metaverse, a term formed by combining meta and universe, has been introduced as a shared virtual world that is fueled by many emerging technologies, such as fifth-generation networks and beyond, virtual reality, and artificial intelligence (AI). Among such technologies, AI has shown the great importance of processing big data to enhance immersive experience and enable human-like intelligence of virtual agents. In this survey, we make a beneficial effort to explore the role of AI in the foundation and development of the metaverse. We first deliver a preliminary of AI, including machine learning algorithms and deep learning architectures, and its role in the metaverse. We then convey a comprehensive investigation of AI-based methods concerning six technical aspects that have potentials for the metaverse: natural language processing, machine vision, blockchain, networking, digital twin, and neural interface, and being potential for the metaverse. Subsequently, several AI-aided applications, such as healthcare, manufacturing, smart cities, and gaming, are studied to be deployed in the virtual worlds. Finally, we conclude the key contribution of this survey and open some future research directions in AI for the metaverse.

Federated learning (FL) has been developed as a promising framework to leverage the resources of edge devices, enhance customers' privacy, comply with regulations, and reduce development costs. Although many methods and applications have been developed for FL, several critical challenges for practical FL systems remain unaddressed. This paper provides an outlook on FL development, categorized into five emerging directions of FL, namely algorithm foundation, personalization, hardware and security constraints, lifelong learning, and nonstandard data. Our unique perspectives are backed by practical observations from large-scale federated systems for edge devices.

Human-in-the-loop aims to train an accurate prediction model with minimum cost by integrating human knowledge and experience. Humans can provide training data for machine learning applications and directly accomplish some tasks that are hard for computers in the pipeline with the help of machine-based approaches. In this paper, we survey existing works on human-in-the-loop from a data perspective and classify them into three categories with a progressive relationship: (1) the work of improving model performance from data processing, (2) the work of improving model performance through interventional model training, and (3) the design of the system independent human-in-the-loop. Using the above categorization, we summarize major approaches in the field, along with their technical strengths/ weaknesses, we have simple classification and discussion in natural language processing, computer vision, and others. Besides, we provide some open challenges and opportunities. This survey intends to provide a high-level summarization for human-in-the-loop and motivates interested readers to consider approaches for designing effective human-in-the-loop solutions.

Imitation learning aims to extract knowledge from human experts' demonstrations or artificially created agents in order to replicate their behaviors. Its success has been demonstrated in areas such as video games, autonomous driving, robotic simulations and object manipulation. However, this replicating process could be problematic, such as the performance is highly dependent on the demonstration quality, and most trained agents are limited to perform well in task-specific environments. In this survey, we provide a systematic review on imitation learning. We first introduce the background knowledge from development history and preliminaries, followed by presenting different taxonomies within Imitation Learning and key milestones of the field. We then detail challenges in learning strategies and present research opportunities with learning policy from suboptimal demonstration, voice instructions and other associated optimization schemes.

Large-scale pre-trained models (PTMs) such as BERT and GPT have recently achieved great success and become a milestone in the field of artificial intelligence (AI). Owing to sophisticated pre-training objectives and huge model parameters, large-scale PTMs can effectively capture knowledge from massive labeled and unlabeled data. By storing knowledge into huge parameters and fine-tuning on specific tasks, the rich knowledge implicitly encoded in huge parameters can benefit a variety of downstream tasks, which has been extensively demonstrated via experimental verification and empirical analysis. It is now the consensus of the AI community to adopt PTMs as backbone for downstream tasks rather than learning models from scratch. In this paper, we take a deep look into the history of pre-training, especially its special relation with transfer learning and self-supervised learning, to reveal the crucial position of PTMs in the AI development spectrum. Further, we comprehensively review the latest breakthroughs of PTMs. These breakthroughs are driven by the surge of computational power and the increasing availability of data, towards four important directions: designing effective architectures, utilizing rich contexts, improving computational efficiency, and conducting interpretation and theoretical analysis. Finally, we discuss a series of open problems and research directions of PTMs, and hope our view can inspire and advance the future study of PTMs.

In the last years, Artificial Intelligence (AI) has achieved a notable momentum that may deliver the best of expectations over many application sectors across the field. For this to occur, the entire community stands in front of the barrier of explainability, an inherent problem of AI techniques brought by sub-symbolism (e.g. ensembles or Deep Neural Networks) that were not present in the last hype of AI. Paradigms underlying this problem fall within the so-called eXplainable AI (XAI) field, which is acknowledged as a crucial feature for the practical deployment of AI models. This overview examines the existing literature in the field of XAI, including a prospect toward what is yet to be reached. We summarize previous efforts to define explainability in Machine Learning, establishing a novel definition that covers prior conceptual propositions with a major focus on the audience for which explainability is sought. We then propose and discuss about a taxonomy of recent contributions related to the explainability of different Machine Learning models, including those aimed at Deep Learning methods for which a second taxonomy is built. This literature analysis serves as the background for a series of challenges faced by XAI, such as the crossroads between data fusion and explainability. Our prospects lead toward the concept of Responsible Artificial Intelligence, namely, a methodology for the large-scale implementation of AI methods in real organizations with fairness, model explainability and accountability at its core. Our ultimate goal is to provide newcomers to XAI with a reference material in order to stimulate future research advances, but also to encourage experts and professionals from other disciplines to embrace the benefits of AI in their activity sectors, without any prior bias for its lack of interpretability.