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Articulatory features can provide interpretable and flexible controls for the synthesis of human vocalizations by allowing the user to directly modify parameters like vocal strain or lip position. To make this manipulation through resynthesis possible, we need to estimate the features that result in a desired vocalization directly from audio recordings. In this work, we propose a white-box optimization technique for estimating glottal source parameters and vocal tract shapes from audio recordings of human vowels. The approach is based on inverse filtering and optimizing the frequency response of a wave\-guide model of the vocal tract with gradient descent, propagating error gradients through the mapping of articulatory features to the vocal tract area function. We apply this method to the task of matching the sound of the Pink Trombone, an interactive articulatory synthesizer, to a given vocalization. We find that our method accurately recovers control functions for audio generated by the Pink Trombone itself. We then compare our technique against evolutionary optimization algorithms and a neural network trained to predict control parameters from audio. A subjective evaluation finds that our approach outperforms these black-box optimization baselines on the task of reproducing human vocalizations.

Age and gender recognition in the wild is a highly challenging task: apart from the variability of conditions, pose complexities, and varying image quality, there are cases where the face is partially or completely occluded. We present MiVOLO (Multi Input VOLO), a straightforward approach for age and gender estimation using the latest vision transformer. Our method integrates both tasks into a unified dual input/output model, leveraging not only facial information but also person image data. This improves the generalization ability of our model and enables it to deliver satisfactory results even when the face is not visible in the image. To evaluate our proposed model, we conduct experiments on four popular benchmarks and achieve state-of-the-art performance, while demonstrating real-time processing capabilities. Additionally, we introduce a novel benchmark based on images from the Open Images Dataset. The ground truth annotations for this benchmark have been meticulously generated by human annotators, resulting in high accuracy answers due to the smart aggregation of votes. Furthermore, we compare our model's age recognition performance with human-level accuracy and demonstrate that it significantly outperforms humans across a majority of age ranges. Finally, we grant public access to our models, along with the code for validation and inference. In addition, we provide extra annotations for used datasets and introduce our new benchmark.

Data objects taking value in a general metric space have become increasingly common in modern data analysis. In this paper, we study two important statistical inference problems, namely, two-sample testing and change-point detection, for such non-Euclidean data under temporal dependence. Typical examples of non-Euclidean valued time series include yearly mortality distributions, time-varying networks, and covariance matrix time series. To accommodate unknown temporal dependence, we advance the self-normalization (SN) technique (Shao, 2010) to the inference of non-Euclidean time series, which is substantially different from the existing SN-based inference for functional time series that reside in Hilbert space (Zhang et al., 2011). Theoretically, we propose new regularity conditions that could be easier to check than those in the recent literature, and derive the limiting distributions of the proposed test statistics under both null and local alternatives. For change-point detection problem, we also derive the consistency for the change-point location estimator, and combine our proposed change-point test with wild binary segmentation to perform multiple change-point estimation. Numerical simulations demonstrate the effectiveness and robustness of our proposed tests compared with existing methods in the literature. Finally, we apply our tests to two-sample inference in mortality data and change-point detection in cryptocurrency data.

The task of lane detection has garnered considerable attention in the field of autonomous driving due to its complexity. Lanes can present difficulties for detection, as they can be narrow, fragmented, and often obscured by heavy traffic. However, it has been observed that the lanes have a geometrical structure that resembles a straight line, leading to improved lane detection results when utilizing this characteristic. To address this challenge, we propose a hierarchical Deep Hough Transform (DHT) approach that combines all lane features in an image into the Hough parameter space. Additionally, we refine the point selection method and incorporate a Dynamic Convolution Module to effectively differentiate between lanes in the original image. Our network architecture comprises a backbone network, either a ResNet or Pyramid Vision Transformer, a Feature Pyramid Network as the neck to extract multi-scale features, and a hierarchical DHT-based feature aggregation head to accurately segment each lane. By utilizing the lane features in the Hough parameter space, the network learns dynamic convolution kernel parameters corresponding to each lane, allowing the Dynamic Convolution Module to effectively differentiate between lane features. Subsequently, the lane features are fed into the feature decoder, which predicts the final position of the lane. Our proposed network structure demonstrates improved performance in detecting heavily occluded or worn lane images, as evidenced by our extensive experimental results, which show that our method outperforms or is on par with state-of-the-art techniques.

Multiplex immunofluorescence (mIF) imaging technology facilitates the study of the tumour microenvironment in cancer patients. Due to the capabilities of this emerging bioimaging technique, it is possible to statistically analyse, for example, the co-varying location and functions of multiple different types of immune cells. Complex spatial relationships between different immune cells have been shown to correlate with patient outcomes and may reveal new pathways for targeted immunotherapy treatments. This tutorial reviews methods and procedures relating to spatial point patterns for complex data analysis. We consider tissue cells as a realisation of a spatial point process for each patient. We focus on proper functional descriptors for each observation and techniques that allow us to obtain information about inter-patient variation. Ovarian cancer is the deadliest gynaecological malignancy and can resist chemotherapy treatment effective in cancers. We use a dataset of high-grade serous ovarian cancer samples from 51 patients. We examine the immune cell composition (T cells, B cells, macrophages) within tumours and additional information such as cell classification (tumour or stroma) and other patient clinical characteristics. Our analyses, supported by reproducible software, apply to other digital pathology datasets.

Generative Adversarial Networks (GANs) have demonstrated their ability to generate synthetic samples that match a target distribution. However, from a privacy perspective, using GANs as a proxy for data sharing is not a safe solution, as they tend to embed near-duplicates of real samples in the latent space. Recent works, inspired by k-anonymity principles, address this issue through sample aggregation in the latent space, with the drawback of reducing the dataset by a factor of k. Our work aims to mitigate this problem by proposing a latent space navigation strategy able to generate diverse synthetic samples that may support effective training of deep models, while addressing privacy concerns in a principled way. Our approach leverages an auxiliary identity classifier as a guide to non-linearly walk between points in the latent space, minimizing the risk of collision with near-duplicates of real samples. We empirically demonstrate that, given any random pair of points in the latent space, our walking strategy is safer than linear interpolation. We then test our path-finding strategy combined to k-same methods and demonstrate, on two benchmarks for tuberculosis and diabetic retinopathy classification, that training a model using samples generated by our approach mitigate drops in performance, while keeping privacy preservation.

Advanced manipulation techniques have provided criminals with opportunities to make social panic or gain illicit profits through the generation of deceptive media, such as forged face images. In response, various deepfake detection methods have been proposed to assess image authenticity. Sequential deepfake detection, which is an extension of deepfake detection, aims to identify forged facial regions with the correct sequence for recovery. Nonetheless, due to the different combinations of spatial and sequential manipulations, forged face images exhibit substantial discrepancies that severely impact detection performance. Additionally, the recovery of forged images requires knowledge of the manipulation model to implement inverse transformations, which is difficult to ascertain as relevant techniques are often concealed by attackers. To address these issues, we propose Multi-Collaboration and Multi-Supervision Network (MMNet) that handles various spatial scales and sequential permutations in forged face images and achieve recovery without requiring knowledge of the corresponding manipulation method. Furthermore, existing evaluation metrics only consider detection accuracy at a single inferring step, without accounting for the matching degree with ground-truth under continuous multiple steps. To overcome this limitation, we propose a novel evaluation metric called Complete Sequence Matching (CSM), which considers the detection accuracy at multiple inferring steps, reflecting the ability to detect integrally forged sequences. Extensive experiments on several typical datasets demonstrate that MMNet achieves state-of-the-art detection performance and independent recovery performance.

Many food products involve mixtures of ingredients, where the mixtures can be expressed as combinations of ingredient proportions. In many cases, the quality and the consumer preference may also depend on the way in which the mixtures are processed. The processing is generally defined by the settings of one or more process variables. Experimental designs studying the joint impact of the mixture ingredient proportions and the settings of the process variables are called mixture-process variable experiments. In this article, we show how to combine mixture-process variable experiments and discrete choice experiments, to quantify and model consumer preferences for food products that can be viewed as processed mixtures. First, we describe the modeling of data from such combined experiments. Next, we describe how to generate D- and I-optimal designs for choice experiments involving mixtures and process variables, and we compare the two kinds of designs using two examples.

This paper focuses on two fundamental tasks of graph analysis: community detection and node representation learning, which capture the global and local structures of graphs, respectively. In the current literature, these two tasks are usually independently studied while they are actually highly correlated. We propose a probabilistic generative model called vGraph to learn community membership and node representation collaboratively. Specifically, we assume that each node can be represented as a mixture of communities, and each community is defined as a multinomial distribution over nodes. Both the mixing coefficients and the community distribution are parameterized by the low-dimensional representations of the nodes and communities. We designed an effective variational inference algorithm which regularizes the community membership of neighboring nodes to be similar in the latent space. Experimental results on multiple real-world graphs show that vGraph is very effective in both community detection and node representation learning, outperforming many competitive baselines in both tasks. We show that the framework of vGraph is quite flexible and can be easily extended to detect hierarchical communities.

It is a common paradigm in object detection frameworks to treat all samples equally and target at maximizing the performance on average. In this work, we revisit this paradigm through a careful study on how different samples contribute to the overall performance measured in terms of mAP. Our study suggests that the samples in each mini-batch are neither independent nor equally important, and therefore a better classifier on average does not necessarily mean higher mAP. Motivated by this study, we propose the notion of Prime Samples, those that play a key role in driving the detection performance. We further develop a simple yet effective sampling and learning strategy called PrIme Sample Attention (PISA) that directs the focus of the training process towards such samples. Our experiments demonstrate that it is often more effective to focus on prime samples than hard samples when training a detector. Particularly, On the MSCOCO dataset, PISA outperforms the random sampling baseline and hard mining schemes, e.g. OHEM and Focal Loss, consistently by more than 1% on both single-stage and two-stage detectors, with a strong backbone ResNeXt-101.