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Clinical trials often involve the assessment of multiple endpoints to comprehensively evaluate the efficacy and safety of interventions. In the work, we consider a global nonparametric testing procedure based on multivariate rank for the analysis of multiple endpoints in clinical trials. Unlike other existing approaches that rely on pairwise comparisons for each individual endpoint, the proposed method directly incorporates the multivariate ranks of the observations. By considering the joint ranking of all endpoints, the proposed approach provides robustness against diverse data distributions and censoring mechanisms commonly encountered in clinical trials. Through extensive simulations, we demonstrate the superior performance of the multivariate rank-based approach in controlling type I error and achieving higher power compared to existing rank-based methods. The simulations illustrate the advantages of leveraging multivariate ranks and highlight the robustness of the approach in various settings. The proposed method offers an effective tool for the analysis of multiple endpoints in clinical trials, enhancing the reliability and efficiency of outcome evaluations.

It is well known that the discrete analogue of a lattice is a linear code which is a vector subspace of Hamming space $\mathbb{F}^n$. The set $\mathbb{F}$ is a finite field and $n \in \mathbb{Z}_{>0}$. Our attempt is to construct a class of lattices such that its discrete analogues are variable length non-linear codes. Let $\mathcal{G}$ and $\mathcal{H}$ be two finite groups, and let $\mathcal{S}$ be a fixed set of generators for $\mathcal{G}$. The homomorphism code is defined as the set of all homomorphisms from $\mathcal{G}$ to $\mathcal{H}$, denoted by, $\mathcal{C} = Hom(\mathcal{G}, \mathcal{H})$. To each homomorphism $\varphi$ between $\mathcal{G}$ and $\mathcal{H}$, a codeword $c_\varphi$ is associated, it is a vector of values of $\varphi$ on the generators in $\mathcal{S}$, that is, $c_\varphi = (\varphi(s_1), \varphi(s_2), \dots, \varphi(s_k))$, where $\varphi(s_i)$ is the image of $s_i \in \mathcal{S}$, $1 \leq i \leq k$. We provide a design to construct a variable length binary non-linear code called as automorphism orbit code from a finite abelian $p$-group of rank more than 1, where $p$ is a prime number. For each finite abelian $p$-group, the codewords of the automorphism orbit code are variable length codewords called as automorphism orbit codewords. Note that homomorphism codes are determined by homomorphisms between groups, whereas automorphism orbit codes are specified by partitions of a number, orbits of a group action, homomorphisms and automorphisms of groups. We make use of elements of $Hom(\mathcal{G}, \mathcal{H})$ to present a cover relation for bit strings of codewords of an automorphism orbit code and formulate a lattice of variable length non-linear codes. Finally, we discuss some information related to the future research work on connections to representation theory of groups and algebras.

Power analysis poses a significant threat to the security of cryptographic algorithms, as it can be leveraged to recover secret keys. While various software-based countermeasures exist to mitigate this non-invasive attack, they often involve a trade-off between time and space constraints. Techniques such as masking and shuffling, while effective, can noticeably impact execution speed and rely heavily on run-time random number generators. On the contrary, internally encoded implementations of block ciphers offer an alternative approach that does not rely on run-time random sources, but it comes with the drawback of requiring substantial memory space to accommodate lookup tables. Internal encoding, commonly employed in white-box cryptography, suffers from a security limitation as it does not effectively protect the secret key against statistical analysis. To overcome this weakness, this paper introduces a secure internal encoding method for an AES implementation. By addressing the root cause of vulnerabilities found in previous encoding methods, we propose a balanced encoding technique that aims to minimize the problematic correlation with key-dependent intermediate values. We analyze the potential weaknesses associated with the balanced encoding and present a method that utilizes complementary sets of lookup tables. In this approach, the size of the lookup tables is approximately 512KB, and the number of table lookups is 1,024. This is comparable to the table size of non-protected white-box AES-128 implementations, while requiring only half the number of lookups. By adopting this method, our aim is to introduce a non-masking technique that mitigates the vulnerability to statistical analysis present in current internally-encoded AES implementations.

Context. Algorithmic racism is the term used to describe the behavior of technological solutions that constrains users based on their ethnicity. Lately, various data-driven software systems have been reported to discriminate against Black people, either for the use of biased data sets or due to the prejudice propagated by software professionals in their code. As a result, Black people are experiencing disadvantages in accessing technology-based services, such as housing, banking, and law enforcement. Goal. This study aims to explore algorithmic racism from the perspective of software professionals. Method. A survey questionnaire was applied to explore the understanding of software practitioners on algorithmic racism, and data analysis was conducted using descriptive statistics and coding techniques. Results. We obtained answers from a sample of 73 software professionals discussing their understanding and perspectives on algorithmic racism in software development. Our results demonstrate that the effects of algorithmic racism are well-known among practitioners. However, there is no consensus on how the problem can be effectively addressed in software engineering. In this paper, some solutions to the problem are proposed based on the professionals' narratives. Conclusion. Combining technical and social strategies, including training on structural racism for software professionals, is the most promising way to address the algorithmic racism problem and its effects on the software solutions delivered to our society.

In the classical communication setting multiple senders having access to the same source of information and transmitting it over channel(s) to a receiver in general leads to a decrease in estimation error at the receiver as compared with the single sender case. However, if the objectives of the information providers are different from that of the estimator, this might result in interesting strategic interactions and outcomes. In this work, we consider a hierarchical signaling game between multiple senders (information designers) and a single receiver (decision maker) each having their own, possibly misaligned, objectives. The senders lead the game by committing to individual information disclosure policies simultaneously, within the framework of a non-cooperative Nash game among themselves. This is followed by the receiver's action decision. With Gaussian information structure and quadratic objectives (which depend on underlying state and receiver's action) for all the players, we show that in general the equilibrium is not unique. We hence identify a set of equilibria and further show that linear noiseless policies can achieve a minimal element of this set. Additionally, we show that competition among the senders is beneficial to the receiver, as compared with cooperation among the senders. Further, we extend our analysis to a dynamic signaling game of finite horizon with Markovian information evolution. We show that linear memoryless policies can achieve equilibrium in this dynamic game. We also consider an extension to a game with multiple receivers having coupled objectives. We provide algorithms to compute the equilibrium strategies in all these cases. Finally, via extensive simulations, we analyze the effects of multiple senders in varying degrees of alignment among their objectives.

We study variable-length codes for point-to-point discrete memoryless channels with noiseless unlimited-rate feedback that occurs in $L$ bursts. We term such codes variable-length bursty-feedback (VLBF) codes. Unlike classical codes with feedback after each transmitted code symbol, bursty feedback fits better with protocols that employ sparse feedback after a packet is sent and also with half-duplex end devices that cannot transmit and listen to the channel at the same time. We present a novel non-asymptotic achievability bound for VLBF codes with $L$ bursts of feedback over any discrete memoryless channel. We numerically evaluate the bound over the binary symmetric channel (BSC). We perform optimization over the time instances at which feedback occurs for both our own bound and Yavas et al.'s non-asymptotic achievability bound for variable-length stop-feedback (VLSF) codes, where only a single bit is sent at each feedback instance. Our results demonstrate the advantages of richer feedback: VLBF codes significantly outperform VLSF codes at short blocklengths, especially as the error probability $\epsilon$ decreases. Remarkably, for BSC(0.11) and error probability $10^{-10}$, our VLBF code with $L=5$ and expected decoding time $N\leq 400$ outperforms the achievability bound given by Polyanskiy et al. for VLSF codes with $L=\infty$, and our VLBF code with $L=3$.

Fact-centric question answering (QA) often requires access to multiple, heterogeneous, information sources. By jointly considering several sources like a knowledge base (KB), a text collection, and tables from the web, QA systems can enhance their answer coverage and confidence. However, existing QA benchmarks are mostly constructed with a single source of knowledge in mind. This limits capabilities of these benchmarks to fairly evaluate QA systems that can tap into more than one information repository. To bridge this gap, we release CompMix, a crowdsourced QA benchmark which naturally demands the integration of a mixture of input sources. CompMix has a total of 9,410 questions, and features several complex intents like joins and temporal conditions. Evaluation of a range of QA systems on CompMix highlights the need for further research on leveraging information from heterogeneous sources.

We propose a model to flexibly estimate joint tail properties by exploiting the convergence of an appropriately scaled point cloud onto a compact limit set. Characteristics of the shape of the limit set correspond to key tail dependence properties. We directly model the shape of the limit set using B\'ezier splines, which allow flexible and parsimonious specification of shapes in two dimensions. We then fit the B\'ezier splines to data in pseudo-polar coordinates using Markov chain Monte Carlo, utilizing a limiting approximation to the conditional likelihood of the radii given angles. By imposing appropriate constraints on the parameters of the B\'ezier splines, we guarantee that each posterior sample is a valid limit set boundary, allowing direct posterior analysis of any quantity derived from the shape of the curve. Furthermore, we obtain interpretable inference on the asymptotic dependence class by using mixture priors with point masses on the corner of the unit box. Finally, we apply our model to bivariate datasets of extremes of variables related to fire risk and air pollution.

Knowledge graphs capture structured information and relations between a set of entities or items. As such they represent an attractive source of information that could help improve recommender systems. However existing approaches in this domain rely on manual feature engineering and do not allow for end-to-end training. Here we propose knowledge-aware graph neural networks with label smoothness regularization to provide better recommendations. Conceptually, our approach computes user-specific item embeddings by first applying a trainable function that identifies important knowledge graph relationships for a given user. This way we transform the knowledge graph into a user-specific weighted graph and then applies a graph neural network to compute personalized item embeddings. To provide better inductive bias, we use label smoothness, which assumes that adjacent items in the knowledge graph are likely to have similar user relevance labels/scores. Label smoothness provides regularization over edge weights and we prove that it is equivalent to a label propagation scheme on a graph. Finally, we combine knowledge-aware graph neural networks and label smoothness and present the unified model. Experiment results show that our method outperforms strong baselines in four datasets. It also achieves strong performance in the scenario where user-item interactions are sparse.

We study the problem of named entity recognition (NER) from electronic medical records, which is one of the most fundamental and critical problems for medical text mining. Medical records which are written by clinicians from different specialties usually contain quite different terminologies and writing styles. The difference of specialties and the cost of human annotation makes it particularly difficult to train a universal medical NER system. In this paper, we propose a label-aware double transfer learning framework (La-DTL) for cross-specialty NER, so that a medical NER system designed for one specialty could be conveniently applied to another one with minimal annotation efforts. The transferability is guaranteed by two components: (i) we propose label-aware MMD for feature representation transfer, and (ii) we perform parameter transfer with a theoretical upper bound which is also label aware. We conduct extensive experiments on 12 cross-specialty NER tasks. The experimental results demonstrate that La-DTL provides consistent accuracy improvement over strong baselines. Besides, the promising experimental results on non-medical NER scenarios indicate that La-DTL is potential to be seamlessly adapted to a wide range of NER tasks.