Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. Current grading systems based on imaging biomarkers only coarsely group disease stages into broad categories and are unable to predict future disease progression. It is widely believed that this is due to their focus on a single point in time, disregarding the dynamic nature of the disease. In this work, we present the first method to automatically discover biomarkers that capture temporal dynamics of disease progression. Our method represents patient time series as trajectories in a latent feature space built with contrastive learning. Then, individual trajectories are partitioned into atomic sub-sequences that encode transitions between disease states. These are clustered using a newly introduced distance metric. In quantitative experiments we found our method yields temporal biomarkers that are predictive of conversion to late AMD. Furthermore, these clusters were highly interpretable to ophthalmologists who confirmed that many of the clusters represent dynamics that have previously been linked to the progression of AMD, even though they are currently not included in any clinical grading system.
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Transfer learning is known to perform efficiently in many applications empirically, yet limited literature reports the mechanism behind the scene. This study establishes both formal derivations and heuristic analysis to formulate the theory of transfer learning in deep learning. Our framework utilizing layer variational analysis proves that the success of transfer learning can be guaranteed with corresponding data conditions. Moreover, our theoretical calculation yields intuitive interpretations towards the knowledge transfer process. Subsequently, an alternative method for network-based transfer learning is derived. The method shows an increase in efficiency and accuracy for domain adaptation. It is particularly advantageous when new domain data is sufficiently sparse during adaptation. Numerical experiments over diverse tasks validated our theory and verified that our analytic expression achieved better performance in domain adaptation than the gradient descent method.
Assessing advancements of technology is essential for creating science and technology policies and making informed investments in the technology market. However, current methods primarily focus on the characteristics of the technologies themselves, making it difficult to accurately assess technologies across various fields and generations. To address this challenge, we propose a novel approach that uses bibliometrics, specifically literature citation networks, to measure changes in knowledge flow throughout the evolution of technology. This method can identify diverse trends in technology development and is an effective tool for evaluating technological advancements. We demonstrate its accuracy and applicability by applying it to mobile communication technology and comparing its quantitative results with other assessment methods. Our work provides critical support for assessing different technical routes and formulating technology policy.
Federated learning involves training statistical models over edge devices such as mobile phones such that the training data is kept local. Federated Learning (FL) can serve as an ideal candidate for training spatial temporal models that rely on heterogeneous and potentially massive numbers of participants while preserving the privacy of highly sensitive location data. However, there are unique challenges involved with transitioning existing spatial temporal models to decentralized learning. In this survey paper, we review the existing literature that has proposed FL-based models for predicting human mobility, traffic prediction, community detection, location-based recommendation systems, and other spatial-temporal tasks. We describe the metrics and datasets these works have been using and create a baseline of these approaches in comparison to the centralized settings. Finally, we discuss the challenges of applying spatial-temporal models in a decentralized setting and by highlighting the gaps in the literature we provide a road map and opportunities for the research community.
Achieving high-quality semantic segmentation predictions using only image-level labels enables a new level of real-world applicability. Although state-of-the-art networks deliver reliable predictions, the amount of handcrafted pixel-wise annotations to enable these results are not feasible in many real-world applications. Hence, several works have already targeted this bottleneck, using classifier-based networks like Class Activation Maps~\cite{CAM} (CAMs) as a base. Addressing CAM's weaknesses of fuzzy borders and incomplete predictions, state-of-the-art approaches rely only on adding regulations to the classifier loss or using pixel-similarity-based refinement after the fact. We propose a framework that introduces an additional module using object perimeters for improved saliency. We define object perimeter information as the line separating the object and background. Our new PerimeterFit module will be applied to pre-refine the CAM predictions before using the pixel-similarity-based network. In this way, our PerimeterFit increases the quality of the CAM prediction while simultaneously improving the false negative rate. We investigated a wide range of state-of-the-art unsupervised semantic segmentation networks and edge detection techniques to create useful perimeter maps, which enable our framework to predict object locations with sharper perimeters. We achieved up to 1.5% improvement over frameworks without our PerimeterFit module. We conduct an exhaustive analysis to illustrate that SILOP enhances existing state-of-the-art frameworks for image-level-based semantic segmentation. The framework is open-source and accessible online at //github.com/ErikOstrowski/SILOP.
In addition to relevance, diversity is an important yet less studied performance metric of cross-modal image retrieval systems, which is critical to user experience. Existing solutions for diversity-aware image retrieval either explicitly post-process the raw retrieval results from standard retrieval systems or try to learn multi-vector representations of images to represent their diverse semantics. However, neither of them is good enough to balance relevance and diversity. On the one hand, standard retrieval systems are usually biased to common semantics and seldom exploit diversity-aware regularization in training, which makes it difficult to promote diversity by post-processing. On the other hand, multi-vector representation methods are not guaranteed to learn robust multiple projections. As a result, irrelevant images and images of rare or unique semantics may be projected inappropriately, which degrades the relevance and diversity of the results generated by some typical algorithms like top-k. To cope with these problems, this paper presents a new method called CoLT that tries to generate much more representative and robust representations for accurately classifying images. Specifically, CoLT first extracts semantics-aware image features by enhancing the preliminary representations of an existing one-to-one cross-modal system with semantics-aware contrastive learning. Then, a transformer-based token classifier is developed to subsume all the features into their corresponding categories. Finally, a post-processing algorithm is designed to retrieve images from each category to form the final retrieval result. Extensive experiments on two real-world datasets Div400 and Div150Cred show that CoLT can effectively boost diversity, and outperforms the existing methods as a whole (with a higher F1 score).
Among various region embedding methods, graph-based region relation learning models stand out, owing to their strong structure representation ability for encoding spatial correlations with graph neural networks. Despite their effectiveness, several key challenges have not been well addressed in existing methods: i) Data noise and missing are ubiquitous in many spatio-temporal scenarios due to a variety of factors. ii) Input spatio-temporal data (e.g., mobility traces) usually exhibits distribution heterogeneity across space and time. In such cases, current methods are vulnerable to the quality of the generated region graphs, which may lead to suboptimal performance. In this paper, we tackle the above challenges by exploring the Automated Spatio-Temporal graph contrastive learning paradigm (AutoST) over the heterogeneous region graph generated from multi-view data sources. Our \model\ framework is built upon a heterogeneous graph neural architecture to capture the multi-view region dependencies with respect to POI semantics, mobility flow patterns and geographical positions. To improve the robustness of our GNN encoder against data noise and distribution issues, we design an automated spatio-temporal augmentation scheme with a parameterized contrastive view generator. AutoST can adapt to the spatio-temporal heterogeneous graph with multi-view semantics well preserved. Extensive experiments for three downstream spatio-temporal mining tasks on several real-world datasets demonstrate the significant performance gain achieved by our \model\ over a variety of baselines. The code is publicly available at //github.com/HKUDS/AutoST.
In recent years, multitudes of researches have applied deep learning to automatic sleep stage classification. Whereas actually, these works have paid less attention to the issue of cross-subject in sleep staging. At the same time, emerging neuroscience theories on inter-subject correlations can provide new insights for cross-subject analysis. This paper presents the MViTime model that have been used in sleep staging study. And we implement the inter-subject correlation theory through contrastive learning, providing a feasible solution to address the cross-subject problem in sleep stage classification. Finally, experimental results and conclusions are presented, demonstrating that the developed method has achieved state-of-the-art performance on sleep staging. The results of the ablation experiment also demonstrate the effectiveness of the cross-subject approach based on contrastive learning.
Recently, a considerable literature has grown up around the theme of Graph Convolutional Network (GCN). How to effectively leverage the rich structural information in complex graphs, such as knowledge graphs with heterogeneous types of entities and relations, is a primary open challenge in the field. Most GCN methods are either restricted to graphs with a homogeneous type of edges (e.g., citation links only), or focusing on representation learning for nodes only instead of jointly propagating and updating the embeddings of both nodes and edges for target-driven objectives. This paper addresses these limitations by proposing a novel framework, namely the Knowledge Embedding based Graph Convolutional Network (KE-GCN), which combines the power of GCNs in graph-based belief propagation and the strengths of advanced knowledge embedding (a.k.a. knowledge graph embedding) methods, and goes beyond. Our theoretical analysis shows that KE-GCN offers an elegant unification of several well-known GCN methods as specific cases, with a new perspective of graph convolution. Experimental results on benchmark datasets show the advantageous performance of KE-GCN over strong baseline methods in the tasks of knowledge graph alignment and entity classification.
Federated learning enables multiple parties to collaboratively train a machine learning model without communicating their local data. A key challenge in federated learning is to handle the heterogeneity of local data distribution across parties. Although many studies have been proposed to address this challenge, we find that they fail to achieve high performance in image datasets with deep learning models. In this paper, we propose MOON: model-contrastive federated learning. MOON is a simple and effective federated learning framework. The key idea of MOON is to utilize the similarity between model representations to correct the local training of individual parties, i.e., conducting contrastive learning in model-level. Our extensive experiments show that MOON significantly outperforms the other state-of-the-art federated learning algorithms on various image classification tasks.
The recent proliferation of knowledge graphs (KGs) coupled with incomplete or partial information, in the form of missing relations (links) between entities, has fueled a lot of research on knowledge base completion (also known as relation prediction). Several recent works suggest that convolutional neural network (CNN) based models generate richer and more expressive feature embeddings and hence also perform well on relation prediction. However, we observe that these KG embeddings treat triples independently and thus fail to cover the complex and hidden information that is inherently implicit in the local neighborhood surrounding a triple. To this effect, our paper proposes a novel attention based feature embedding that captures both entity and relation features in any given entity's neighborhood. Additionally, we also encapsulate relation clusters and multihop relations in our model. Our empirical study offers insights into the efficacy of our attention based model and we show marked performance gains in comparison to state of the art methods on all datasets.
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