Image segmentation holds a vital position in the realms of diagnosis and treatment within the medical domain. Traditional convolutional neural networks (CNNs) and Transformer models have made significant advancements in this realm, but they still encounter challenges because of limited receptive field or high computing complexity. Recently, State Space Models (SSMs), particularly Mamba and its variants, have demonstrated notable performance in the field of vision. However, their feature extraction methods may not be sufficiently effective and retain some redundant structures, leaving room for parameter reduction. Motivated by previous spatial and channel attention methods, we propose Triplet Mamba-UNet. The method leverages residual VSS Blocks to extract intensive contextual features, while Triplet SSM is employed to fuse features across spatial and channel dimensions. We conducted experiments on ISIC17, ISIC18, CVC-300, CVC-ClinicDB, Kvasir-SEG, CVC-ColonDB, and Kvasir-Instrument datasets, demonstrating the superior segmentation performance of our proposed TM-UNet. Additionally, compared to the previous VM-UNet, our model achieves a one-third reduction in parameters.
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Patient transfer devices allow to move patients passively in hospitals and care centers. Instead of hoisting the patient, it would be beneficial in some cases to assist their movement, enabling them to move by themselves. However, patient assistance requires devices capable of precisely controlling output forces at significantly higher speeds than those used for patient transfers alone, and a single motor solution would be over-sized and show poor efficiency to do both functions. This paper presents a dual-motor actuator and control schemes adapted for a patient mobility equipment that can be used to transfer patients, assist patient in their movement, and help prevent falls. The prototype is shown to be able to lift patients weighing up to 318 kg, to assist a patient with a desired force of up to 100 kg with a precision of 7.8%. Also, a smart control scheme to manage falls is shown to be able to stop a patient who is falling by applying a desired deceleration.
Automatic medical image segmentation technology has the potential to expedite pathological diagnoses, thereby enhancing the efficiency of patient care. However, medical images often have complex textures and structures, and the models often face the problem of reduced image resolution and information loss due to downsampling. To address this issue, we propose HC-Mamba, a new medical image segmentation model based on the modern state space model Mamba. Specifically, we introduce the technique of dilated convolution in the HC-Mamba model to capture a more extensive range of contextual information without increasing the computational cost by extending the perceptual field of the convolution kernel. In addition, the HC-Mamba model employs depthwise separable convolutions, significantly reducing the number of parameters and the computational power of the model. By combining dilated convolution and depthwise separable convolutions, HC-Mamba is able to process large-scale medical image data at a much lower computational cost while maintaining a high level of performance. We conduct comprehensive experiments on segmentation tasks including skin lesion, and conduct extensive experiments on ISIC17 and ISIC18 to demonstrate the potential of the HC-Mamba model in medical image segmentation. The experimental results show that HC-Mamba exhibits competitive performance on all these datasets, thereby proving its effectiveness and usefulness in medical image segmentation.
Over the past two decades, machine analysis of medical imaging has advanced rapidly, opening up significant potential for several important medical applications. As complicated diseases increase and the number of cases rises, the role of machine-based imaging analysis has become indispensable. It serves as both a tool and an assistant to medical experts, providing valuable insights and guidance. A particularly challenging task in this area is lesion segmentation, a task that is challenging even for experienced radiologists. The complexity of this task highlights the urgent need for robust machine learning approaches to support medical staff. In response, we present our novel solution: the D-TrAttUnet architecture. This framework is based on the observation that different diseases often target specific organs. Our architecture includes an encoder-decoder structure with a composite Transformer-CNN encoder and dual decoders. The encoder includes two paths: the Transformer path and the Encoders Fusion Module path. The Dual-Decoder configuration uses two identical decoders, each with attention gates. This allows the model to simultaneously segment lesions and organs and integrate their segmentation losses. To validate our approach, we performed evaluations on the Covid-19 and Bone Metastasis segmentation tasks. We also investigated the adaptability of the model by testing it without the second decoder in the segmentation of glands and nuclei. The results confirmed the superiority of our approach, especially in Covid-19 infections and the segmentation of bone metastases. In addition, the hybrid encoder showed exceptional performance in the segmentation of glands and nuclei, solidifying its role in modern medical image analysis.
With the mainstream integration of machine learning into security-sensitive domains such as healthcare and finance, concerns about data privacy have intensified. Conventional artificial neural networks (ANNs) have been found vulnerable to several attacks that can leak sensitive data. Particularly, model inversion (MI) attacks enable the reconstruction of data samples that have been used to train the model. Neuromorphic architectures have emerged as a paradigm shift in neural computing, enabling asynchronous and energy-efficient computation. However, little to no existing work has investigated the privacy of neuromorphic architectures against model inversion. Our study is motivated by the intuition that the non-differentiable aspect of spiking neural networks (SNNs) might result in inherent privacy-preserving properties, especially against gradient-based attacks. To investigate this hypothesis, we propose a thorough exploration of SNNs' privacy-preserving capabilities. Specifically, we develop novel inversion attack strategies that are comprehensively designed to target SNNs, offering a comparative analysis with their conventional ANN counterparts. Our experiments, conducted on diverse event-based and static datasets, demonstrate the effectiveness of the proposed attack strategies and therefore questions the assumption of inherent privacy-preserving in neuromorphic architectures.
Training with noisy class labels impairs neural networks' generalization performance. In this context, mixup is a popular regularization technique to improve training robustness by making memorizing false class labels more difficult. However, mixup neglects that, typically, multiple annotators, e.g., crowdworkers, provide class labels. Therefore, we propose an extension of mixup, which handles multiple class labels per instance while considering which class label originates from which annotator. Integrated into our multi-annotator classification framework annot-mix, it performs superiorly to eight state-of-the-art approaches on eleven datasets with noisy class labels provided either by human or simulated annotators. Our code is publicly available through our repository at //github.com/ies-research/annot-mix.
Owing to their powerful semantic reasoning capabilities, Large Language Models (LLMs) have been effectively utilized as recommenders, achieving impressive performance. However, the high inference latency of LLMs significantly restricts their practical deployment. To address this issue, this work investigates knowledge distillation from cumbersome LLM-based recommendation models to lightweight conventional sequential models. It encounters three challenges: 1) the teacher's knowledge may not always be reliable; 2) the capacity gap between the teacher and student makes it difficult for the student to assimilate the teacher's knowledge; 3) divergence in semantic space poses a challenge to distill the knowledge from embeddings. To tackle these challenges, this work proposes a novel distillation strategy, DLLM2Rec, specifically tailored for knowledge distillation from LLM-based recommendation models to conventional sequential models. DLLM2Rec comprises: 1) Importance-aware ranking distillation, which filters reliable and student-friendly knowledge by weighting instances according to teacher confidence and student-teacher consistency; 2) Collaborative embedding distillation integrates knowledge from teacher embeddings with collaborative signals mined from the data. Extensive experiments demonstrate the effectiveness of the proposed DLLM2Rec, boosting three typical sequential models with an average improvement of 47.97%, even enabling them to surpass LLM-based recommenders in some cases.
The acquisition of different data modalities can enhance our knowledge and understanding of various diseases, paving the way for a more personalized healthcare. Thus, medicine is progressively moving towards the generation of massive amounts of multi-modal data (\emph{e.g,} molecular, radiology, and histopathology). While this may seem like an ideal environment to capitalize data-centric machine learning approaches, most methods still focus on exploring a single or a pair of modalities due to a variety of reasons: i) lack of ready to use curated datasets; ii) difficulty in identifying the best multi-modal fusion strategy; and iii) missing modalities across patients. In this paper we introduce a real world multi-modal dataset called MMIST-CCRCC that comprises 2 radiology modalities (CT and MRI), histopathology, genomics, and clinical data from 618 patients with clear cell renal cell carcinoma (ccRCC). We provide single and multi-modal (early and late fusion) benchmarks in the task of 12-month survival prediction in the challenging scenario of one or more missing modalities for each patient, with missing rates that range from 26$\%$ for genomics data to more than 90$\%$ for MRI. We show that even with such severe missing rates the fusion of modalities leads to improvements in the survival forecasting. Additionally, incorporating a strategy to generate the latent representations of the missing modalities given the available ones further improves the performance, highlighting a potential complementarity across modalities. Our dataset and code are available here: //multi-modal-ist.github.io/datasets/ccRCC
Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.
We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image while highlighting salient features useful for a specific task. This enables us to eliminate the necessity of using explicit external tissue/organ localisation modules of cascaded convolutional neural networks (CNNs). AGs can be easily integrated into standard CNN architectures such as the U-Net model with minimal computational overhead while increasing the model sensitivity and prediction accuracy. The proposed Attention U-Net architecture is evaluated on two large CT abdominal datasets for multi-class image segmentation. Experimental results show that AGs consistently improve the prediction performance of U-Net across different datasets and training sizes while preserving computational efficiency. The code for the proposed architecture is publicly available.
Many natural language processing tasks solely rely on sparse dependencies between a few tokens in a sentence. Soft attention mechanisms show promising performance in modeling local/global dependencies by soft probabilities between every two tokens, but they are not effective and efficient when applied to long sentences. By contrast, hard attention mechanisms directly select a subset of tokens but are difficult and inefficient to train due to their combinatorial nature. In this paper, we integrate both soft and hard attention into one context fusion model, "reinforced self-attention (ReSA)", for the mutual benefit of each other. In ReSA, a hard attention trims a sequence for a soft self-attention to process, while the soft attention feeds reward signals back to facilitate the training of the hard one. For this purpose, we develop a novel hard attention called "reinforced sequence sampling (RSS)", selecting tokens in parallel and trained via policy gradient. Using two RSS modules, ReSA efficiently extracts the sparse dependencies between each pair of selected tokens. We finally propose an RNN/CNN-free sentence-encoding model, "reinforced self-attention network (ReSAN)", solely based on ReSA. It achieves state-of-the-art performance on both Stanford Natural Language Inference (SNLI) and Sentences Involving Compositional Knowledge (SICK) datasets.
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