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Learning performance data, such as correct or incorrect responses to questions in Intelligent Tutoring Systems (ITSs) is crucial for tracking and assessing the learners' progress and mastery of knowledge. However, the issue of data sparsity, characterized by unexplored questions and missing attempts, hampers accurate assessment and the provision of tailored, personalized instruction within ITSs. This paper proposes using the Generative Adversarial Imputation Networks (GAIN) framework to impute sparse learning performance data, reconstructed into a three-dimensional (3D) tensor representation across the dimensions of learners, questions and attempts. Our customized GAIN-based method computational process imputes sparse data in a 3D tensor space, significantly enhanced by convolutional neural networks for its input and output layers. This adaptation also includes the use of a least squares loss function for optimization and aligns the shapes of the input and output with the dimensions of the questions-attempts matrices along the learners' dimension. Through extensive experiments on six datasets from various ITSs, including AutoTutor, ASSISTments and MATHia, we demonstrate that the GAIN approach generally outperforms existing methods such as tensor factorization and other generative adversarial network (GAN) based approaches in terms of imputation accuracy. This finding enhances comprehensive learning data modeling and analytics in AI-based education.

Knowledge Graph Embedding (KGE) is a popular approach, which aims to represent entities and relations of a knowledge graph in latent spaces. Their representations are known as embeddings. To measure the plausibility of triplets, score functions are defined over embedding spaces. Despite wide dissemination of KGE in various tasks, KGE methods have limitations in reasoning abilities. In this paper we propose a mathematical framework to compare reasoning abilities of KGE methods. We show that STransE has a higher capability than TransComplEx, and then present new STransCoRe method, which improves the STransE by combining it with the TransCoRe insights, which can reduce the STransE space complexity.

Major depressive disorder (MDD) presents challenges in diagnosis and treatment due to its complex and heterogeneous nature. Emerging evidence indicates that reward processing abnormalities may serve as a behavioral marker for MDD. To measure reward processing, patients perform computer-based behavioral tasks that involve making choices or responding to stimulants that are associated with different outcomes. Reinforcement learning (RL) models are fitted to extract parameters that measure various aspects of reward processing to characterize how patients make decisions in behavioral tasks. Recent findings suggest the inadequacy of characterizing reward learning solely based on a single RL model; instead, there may be a switching of decision-making processes between multiple strategies. An important scientific question is how the dynamics of learning strategies in decision-making affect the reward learning ability of individuals with MDD. Motivated by the probabilistic reward task (PRT) within the EMBARC study, we propose a novel RL-HMM framework for analyzing reward-based decision-making. Our model accommodates learning strategy switching between two distinct approaches under a hidden Markov model (HMM): subjects making decisions based on the RL model or opting for random choices. We account for continuous RL state space and allow time-varying transition probabilities in the HMM. We introduce a computationally efficient EM algorithm for parameter estimation and employ a nonparametric bootstrap for inference. We apply our approach to the EMBARC study to show that MDD patients are less engaged in RL compared to the healthy controls, and engagement is associated with brain activities in the negative affect circuitry during an emotional conflict task.

Federated Learning (FL) is the most widely adopted collaborative learning approach for training decentralized Machine Learning (ML) models by exchanging learning between clients without sharing the data and compromising privacy. However, since great data similarity or homogeneity is taken for granted in all FL tasks, FL is still not specifically designed for the industrial setting. Rarely this is the case in industrial data because there are differences in machine type, firmware version, operational conditions, environmental factors, and hence, data distribution. Albeit its popularity, it has been observed that FL performance degrades if the clients have heterogeneous data distributions. Therefore, we propose a Lightweight Industrial Cohorted FL (LICFL) algorithm that uses model parameters for cohorting without any additional on-edge (clientlevel) computations and communications than standard FL and mitigates the shortcomings from data heterogeneity in industrial applications. Our approach enhances client-level model performance by allowing them to collaborate with similar clients and train more specialized or personalized models. Also, we propose an adaptive aggregation algorithm that extends the LICFL to Adaptive LICFL (ALICFL) for further improving the global model performance and speeding up the convergence. Through numerical experiments on real-time data, we demonstrate the efficacy of the proposed algorithms and compare the performance with existing approaches.

Survival prediction for cancer patients is critical for optimal treatment selection and patient management. Current patient survival prediction methods typically extract survival information from patients' clinical record data or biological and imaging data. In practice, experienced clinicians can have a preliminary assessment of patients' health status based on patients' observable physical appearances, which are mainly facial features. However, such assessment is highly subjective. In this work, the efficacy of objectively capturing and using prognostic information contained in conventional portrait photographs using deep learning for survival predication purposes is investigated for the first time. A pre-trained StyleGAN2 model is fine-tuned on a custom dataset of our cancer patients' photos to empower its generator with generative ability suitable for patients' photos. The StyleGAN2 is then used to embed the photographs to its highly expressive latent space. Utilizing the state-of-the-art survival analysis models and based on StyleGAN's latent space photo embeddings, this approach achieved a C-index of 0.677, which is notably higher than chance and evidencing the prognostic value embedded in simple 2D facial images. In addition, thanks to StyleGAN's interpretable latent space, our survival prediction model can be validated for relying on essential facial features, eliminating any biases from extraneous information like clothing or background. Moreover, a health attribute is obtained from regression coefficients, which has important potential value for patient care.

The scalar auxiliary variable (SAV) approach is a highly efficient method widely used for solving gradient flow systems. This approach offers several advantages, including linearity, unconditional energy stability, and ease of implementation. By introducing scalar auxiliary variables, a modified system that is equivalent to the original system is constructed at the continuous level. However, during temporal discretization, computational errors can lead to a loss of equivalence and accuracy. In this paper, we introduce a new Constant Scalar Auxiliary Variable (CSAV) approach in which we derive an Ordinary Differential Equation (ODE) for the constant scalar auxiliary variable r. We also introduce a stabilization parameter ({\alpha}) to improve the stability of the scheme by slowing down the dynamics of r. The CSAV approach provides additional benefits as well. We explicitly discretize the auxiliary variable in combination with the nonlinear term, enabling the solution of a single linear system with constant coefficients at each time step. This new approach also eliminates the need for assumptions about the free energy potential, removing the bounded-from-below restriction imposed by the nonlinear free energy potential in the original SAV approach. Finally, we validate the proposed method through extensive numerical simulations, demonstrating its effectiveness and accuracy.

The diversity in disease profiles and therapeutic approaches between hospitals and health professionals underscores the need for patient-centric personalized strategies in healthcare. Alongside this, similarities in disease progression across patients can be utilized to improve prediction models in survival analysis. The need for patient privacy and the utility of prediction models can be simultaneously addressed in the framework of Federated Learning (FL). This paper outlines an approach in the domain of federated survival analysis, specifically the Cox Proportional Hazards (CoxPH) model, with a specific focus on mitigating data heterogeneity and elevating model performance. We present an FL approach that employs feature-based clustering to enhance model accuracy across synthetic datasets and real-world applications, including the Surveillance, Epidemiology, and End Results (SEER) database. Furthermore, we consider an event-based reporting strategy that provides a dynamic approach to model adaptation by responding to local data changes. Our experiments show the efficacy of our approach and discuss future directions for a practical application of FL in healthcare.

Recent contrastive representation learning methods rely on estimating mutual information (MI) between multiple views of an underlying context. E.g., we can derive multiple views of a given image by applying data augmentation, or we can split a sequence into views comprising the past and future of some step in the sequence. Contrastive lower bounds on MI are easy to optimize, but have a strong underestimation bias when estimating large amounts of MI. We propose decomposing the full MI estimation problem into a sum of smaller estimation problems by splitting one of the views into progressively more informed subviews and by applying the chain rule on MI between the decomposed views. This expression contains a sum of unconditional and conditional MI terms, each measuring modest chunks of the total MI, which facilitates approximation via contrastive bounds. To maximize the sum, we formulate a contrastive lower bound on the conditional MI which can be approximated efficiently. We refer to our general approach as Decomposed Estimation of Mutual Information (DEMI). We show that DEMI can capture a larger amount of MI than standard non-decomposed contrastive bounds in a synthetic setting, and learns better representations in a vision domain and for dialogue generation.

Few-shot Knowledge Graph (KG) completion is a focus of current research, where each task aims at querying unseen facts of a relation given its few-shot reference entity pairs. Recent attempts solve this problem by learning static representations of entities and references, ignoring their dynamic properties, i.e., entities may exhibit diverse roles within task relations, and references may make different contributions to queries. This work proposes an adaptive attentional network for few-shot KG completion by learning adaptive entity and reference representations. Specifically, entities are modeled by an adaptive neighbor encoder to discern their task-oriented roles, while references are modeled by an adaptive query-aware aggregator to differentiate their contributions. Through the attention mechanism, both entities and references can capture their fine-grained semantic meanings, and thus render more expressive representations. This will be more predictive for knowledge acquisition in the few-shot scenario. Evaluation in link prediction on two public datasets shows that our approach achieves new state-of-the-art results with different few-shot sizes.

Clinical Named Entity Recognition (CNER) aims to identify and classify clinical terms such as diseases, symptoms, treatments, exams, and body parts in electronic health records, which is a fundamental and crucial task for clinical and translational research. In recent years, deep neural networks have achieved significant success in named entity recognition and many other Natural Language Processing (NLP) tasks. Most of these algorithms are trained end to end, and can automatically learn features from large scale labeled datasets. However, these data-driven methods typically lack the capability of processing rare or unseen entities. Previous statistical methods and feature engineering practice have demonstrated that human knowledge can provide valuable information for handling rare and unseen cases. In this paper, we address the problem by incorporating dictionaries into deep neural networks for the Chinese CNER task. Two different architectures that extend the Bi-directional Long Short-Term Memory (Bi-LSTM) neural network and five different feature representation schemes are proposed to handle the task. Computational results on the CCKS-2017 Task 2 benchmark dataset show that the proposed method achieves the highly competitive performance compared with the state-of-the-art deep learning methods.