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To promote the generalization ability of breast tumor segmentation models, as well as to improve the segmentation performance for breast tumors with smaller size, low-contrast amd irregular shape, we propose a progressive dual priori network (PDPNet) to segment breast tumors from dynamic enhanced magnetic resonance images (DCE-MRI) acquired at different sites. The PDPNet first cropped tumor regions with a coarse-segmentation based localization module, then the breast tumor mask was progressively refined by using the weak semantic priori and cross-scale correlation prior knowledge. To validate the effectiveness of PDPNet, we compared it with several state-of-the-art methods on multi-center datasets. The results showed that, comparing against the suboptimal method, the DSC, SEN, KAPPA and HD95 of PDPNet were improved 3.63\%, 8.19\%, 5.52\%, and 3.66\% respectively. In addition, through ablations, we demonstrated that the proposed localization module can decrease the influence of normal tissues and therefore improve the generalization ability of the model. The weak semantic priors allow focusing on tumor regions to avoid missing small tumors and low-contrast tumors. The cross-scale correlation priors are beneficial for promoting the shape-aware ability for irregual tumors. Thus integrating them in a unified framework improved the multi-center breast tumor segmentation performance.

A fundamental limitation of object detectors is that they suffer from "spatial bias", and in particular perform less satisfactorily when detecting objects near image borders. For a long time, there has been a lack of effective ways to measure and identify spatial bias, and little is known about where it comes from and what degree it is. To this end, we present a new zone evaluation protocol, extending from the traditional evaluation to a more generalized one, which measures the detection performance over zones, yielding a series of Zone Precisions (ZPs). For the first time, we provide numerical results, showing that the object detectors perform quite unevenly across the zones. Surprisingly, the detector's performance in the 96\% border zone of the image does not reach the AP value (Average Precision, commonly regarded as the average detection performance in the entire image zone). To better understand spatial bias, a series of heuristic experiments are conducted. Our investigation excludes two intuitive conjectures about spatial bias that the object scale and the absolute positions of objects barely influence the spatial bias. We find that the key lies in the human-imperceptible divergence in data patterns between objects in different zones, thus eventually forming a visible performance gap between the zones. With these findings, we finally discuss a future direction for object detection, namely, spatial disequilibrium problem, aiming at pursuing a balanced detection ability over the entire image zone. By broadly evaluating 10 popular object detectors and 5 detection datasets, we shed light on the spatial bias of object detectors. We hope this work could raise a focus on detection robustness. The source codes, evaluation protocols, and tutorials are publicly available at \url{//github.com/Zzh-tju/ZoneEval}.

Decomposing a target object from a complex background while reconstructing is challenging. Most approaches acquire the perception for object instances through the use of manual labels, but the annotation procedure is costly. The recent advancements in 2D self-supervised learning have brought new prospects to object-aware representation, yet it remains unclear how to leverage such noisy 2D features for clean decomposition. In this paper, we propose a Decomposed Object Reconstruction (DORec) network based on neural implicit representations. Our key idea is to transfer 2D self-supervised features into masks of two levels of granularity to supervise the decomposition, including a binary mask to indicate the foreground regions and a K-cluster mask to indicate the semantically similar regions. These two masks are complementary to each other and lead to robust decomposition. Experimental results show the superiority of DORec in segmenting and reconstructing the foreground object on various datasets.

The simplex gradient, a popular numerical differentiation method due to its flexibility, lacks a principled method by which to construct the sample set, specifically the location of function evaluations. Such evaluations, especially from real-world systems, are often noisy and expensive to obtain, making it essential that each evaluation is carefully chosen to reduce cost and increase accuracy. This paper introduces the curvature aligned simplex gradient (CASG), which provably selects the optimal sample set under a mean squared error objective. As CASG requires function-dependent information often not available in practice, we additionally introduce a framework which exploits a history of function evaluations often present in practical applications. Our numerical results, focusing on applications in sensitivity analysis and derivative free optimization, show that our methodology significantly outperforms or matches the performance of the benchmark gradient estimator given by forward differences (FD) which is given exact function-dependent information that is not available in practice. Furthermore, our methodology is comparable to the performance of central differences (CD) that requires twice the number of function evaluations.

We consider rather a general class of multi-level optimization problems, where a convex objective function is to be minimized subject to constraints of optimality of nested convex optimization problems. As a special case, we consider a trilevel optimization problem, where the objective of the two lower layers consists of a sum of a smooth and a non-smooth term.~Based on fixed-point theory and related arguments, we present a natural first-order algorithm and analyze its convergence and rates of convergence in several regimes of parameters.

Massive multiple-input multiple-output (MIMO) has gained widespread popularity in recent years due to its ability to increase data rates, improve signal quality, and provide better coverage in challenging environments. In this paper, we investigate the MIMO beam selection (MBS) problem, which is proven to be NP-hard and computationally intractable. To deal with this problem, quantum computing that can provide faster and more efficient solutions to large-scale combinatorial optimization is considered. MBS is formulated in a quadratic unbounded binary optimization form and solved with Coherent Ising Machine (CIM) physical machine. We compare the performance of our solution with two classic heuristics, simulated annealing and Tabu search. The results demonstrate an average performance improvement by a factor of 261.23 and 20.6, respectively, which shows that CIM-based solution performs significantly better in terms of selecting the optimal subset of beams. This work shows great promise for practical 5G operation and promotes the application of quantum computing in solving computationally hard problems in communication.

Existing regression models tend to fall short in both accuracy and uncertainty estimation when the label distribution is imbalanced. In this paper, we propose a probabilistic deep learning model, dubbed variational imbalanced regression (VIR), which not only performs well in imbalanced regression but naturally produces reasonable uncertainty estimation as a byproduct. Different from typical variational autoencoders assuming I.I.D. representations (a data point's representation is not directly affected by other data points), our VIR borrows data with similar regression labels to compute the latent representation's variational distribution; furthermore, different from deterministic regression models producing point estimates, VIR predicts the entire normal-inverse-gamma distributions and modulates the associated conjugate distributions to impose probabilistic reweighting on the imbalanced data, thereby providing better uncertainty estimation. Experiments in several real-world datasets show that our VIR can outperform state-of-the-art imbalanced regression models in terms of both accuracy and uncertainty estimation. Code will soon be available at //github.com/Wang-ML-Lab/variational-imbalanced-regression.

We provide a variety of lower bounds for the well-known shortcut set problem: how much can one decrease the diameter of a directed graph on $n$ vertices and $m$ edges by adding $O(n)$ or $O(m)$ of shortcuts from the transitive closure of the graph. Our results are based on a vast simplification of the recent construction of Bodwin and Hoppenworth [FOCS 2023] which was used to show an $\widetilde{\Omega}(n^{1/4})$ lower bound for the $O(n)$-sized shortcut set problem. We highlight that our simplification completely removes the use of the convex sets by B\'ar\'any and Larman [Math. Ann. 1998] used in all previous lower bound constructions. Our simplification also removes the need for randomness and further removes some log factors. This allows us to generalize the construction to higher dimensions, which in turn can be used to show the following results. For $O(m)$-sized shortcut sets, we show an $\Omega(n^{1/5})$ lower bound, improving on the previous best $\Omega(n^{1/8})$ lower bound. For all $\varepsilon > 0$, we show that there exists a $\delta > 0$ such that there are $n$-vertex $O(n)$-edge graphs $G$ where adding any shortcut set of size $O(n^{2-\varepsilon})$ keeps the diameter of $G$ at $\Omega(n^\delta)$. This improves the sparsity of the constructed graph compared to a known similar result by Hesse [SODA 2003]. We also consider the sourcewise setting for shortcut sets: given a graph $G=(V,E)$, a set $S\subseteq V$, how much can we decrease the sourcewise diameter of $G$, $\max_{(s, v) \in S \times V, \text{dist}(s, v) < \infty} \text{dist}(s,v)$ by adding a set of edges $H$ from the transitive closure of $G$? We show that for any integer $d \ge 2$, there exists a graph $G=(V, E)$ on $n$ vertices and $S \subseteq V$ with $|S| = \widetilde{\Theta}(n^{3/(d+3)})$, such that when adding $O(n)$ or $O(m)$ shortcuts, the sourcewise diameter is $\widetilde{\Omega}(|S|^{1/3})$.

Generative commonsense reasoning which aims to empower machines to generate sentences with the capacity of reasoning over a set of concepts is a critical bottleneck for text generation. Even the state-of-the-art pre-trained language generation models struggle at this task and often produce implausible and anomalous sentences. One reason is that they rarely consider incorporating the knowledge graph which can provide rich relational information among the commonsense concepts. To promote the ability of commonsense reasoning for text generation, we propose a novel knowledge graph augmented pre-trained language generation model KG-BART, which encompasses the complex relations of concepts through the knowledge graph and produces more logical and natural sentences as output. Moreover, KG-BART can leverage the graph attention to aggregate the rich concept semantics that enhances the model generalization on unseen concept sets. Experiments on benchmark CommonGen dataset verify the effectiveness of our proposed approach by comparing with several strong pre-trained language generation models, particularly KG-BART outperforms BART by 5.80, 4.60, in terms of BLEU-3, 4. Moreover, we also show that the generated context by our model can work as background scenarios to benefit downstream commonsense QA tasks.

Distant supervision can effectively label data for relation extraction, but suffers from the noise labeling problem. Recent works mainly perform soft bag-level noise reduction strategies to find the relatively better samples in a sentence bag, which is suboptimal compared with making a hard decision of false positive samples in sentence level. In this paper, we introduce an adversarial learning framework, which we named DSGAN, to learn a sentence-level true-positive generator. Inspired by Generative Adversarial Networks, we regard the positive samples generated by the generator as the negative samples to train the discriminator. The optimal generator is obtained until the discrimination ability of the discriminator has the greatest decline. We adopt the generator to filter distant supervision training dataset and redistribute the false positive instances into the negative set, in which way to provide a cleaned dataset for relation classification. The experimental results show that the proposed strategy significantly improves the performance of distant supervision relation extraction comparing to state-of-the-art systems.