Skin Lesion Segmentation Improved by Transformer-based Networks with Inter-scale Dependency Modeling
Melanoma, a dangerous type of skin cancer resulting from abnormal skin cell growth, can be treated if detected early. Various approaches using Fully Convolutional Networks (FCNs) have been proposed, with the U-Net architecture being prominent To aid in its diagnosis through automatic skin lesion segmentation. However, the symmetrical U-Net model's reliance on convolutional operations hinders its ability to capture long-range dependencies crucial for accurate medical image segmentation. Several Transformer-based U-Net topologies have recently been created to overcome this limitation by replacing CNN blocks with different Transformer modules to capture local and global representations. Furthermore, the U-shaped structure is hampered by semantic gaps between the encoder and decoder. This study intends to increase the network's feature re-usability by carefully building the skip connection path. Integrating an already calculated attention affinity within the skip connection path improves the typical concatenation process utilized in the conventional skip connection path. As a result, we propose a U-shaped hierarchical Transformer-based structure for skin lesion segmentation and an Inter-scale Context Fusion (ISCF) method that uses attention correlations in each stage of the encoder to adaptively combine the contexts from each stage to mitigate semantic gaps. The findings from two skin lesion segmentation benchmarks support the ISCF module's applicability and effectiveness. The code is publicly available at \url{//github.com/saniaesk/skin-lesion-segmentation}
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The performance of automatic summarization models has improved dramatically in recent years. Yet, there is still a gap in meeting specific information needs of users in real-world scenarios, particularly when a targeted summary is sought, such as in the useful aspect-based summarization setting targeted in this paper. Previous datasets and studies for this setting have predominantly concentrated on a limited set of pre-defined aspects, focused solely on single document inputs, or relied on synthetic data. To advance research on more realistic scenarios, we introduce OpenAsp, a benchmark for multi-document \textit{open} aspect-based summarization. This benchmark is created using a novel and cost-effective annotation protocol, by which an open aspect dataset is derived from existing generic multi-document summarization datasets. We analyze the properties of OpenAsp showcasing its high-quality content. Further, we show that the realistic open-aspect setting realized in OpenAsp poses a challenge for current state-of-the-art summarization models, as well as for large language models.
The coordination between agents in multi-agent systems has become a popular topic in many fields. To catch the inner relationship between agents, the graph structure is combined with existing methods and improves the results. But in large-scale tasks with numerous agents, an overly complex graph would lead to a boost in computational cost and a decline in performance. Here we present DAGMIX, a novel graph-based value factorization method. Instead of a complete graph, DAGMIX generates a dynamic graph at each time step during training, on which it realizes a more interpretable and effective combining process through the attention mechanism. Experiments show that DAGMIX significantly outperforms previous SOTA methods in large-scale scenarios, as well as achieving promising results on other tasks.
Most convolutional neural network (CNN) based methods for skin cancer classification obtain their results using only dermatological images. Although good classification results have been shown, more accurate results can be achieved by considering the patient's metadata, which is valuable clinical information for dermatologists. Current methods only use the simple joint fusion structure (FS) and fusion modules (FMs) for the multi-modal classification methods, there still is room to increase the accuracy by exploring more advanced FS and FM. Therefore, in this paper, we design a new fusion method that combines dermatological images (dermoscopy images or clinical images) and patient metadata for skin cancer classification from the perspectives of FS and FM. First, we propose a joint-individual fusion (JIF) structure that learns the shared features of multi-modality data and preserves specific features simultaneously. Second, we introduce a fusion attention (FA) module that enhances the most relevant image and metadata features based on both the self and mutual attention mechanism to support the decision-making pipeline. We compare the proposed JIF-MMFA method with other state-of-the-art fusion methods on three different public datasets. The results show that our JIF-MMFA method improves the classification results for all tested CNN backbones and performs better than the other fusion methods on the three public datasets, demonstrating our method's effectiveness and robustness
We introduce three notions of multivariate median bias, namely, rectilinear, Tukey, and orthant median bias. Each of these median biases is zero under a suitable notion of multivariate symmetry. We study the coverage probabilities of rectangular hull of $B$ independent multivariate estimators, with special attention to the number of estimators $B$ needed to ensure a miscoverage of at most $\alpha$. It is proved that for estimators with zero orthant median bias, we need $B\geq c\log_2(d/\alpha)$ for some constant $c > 0$. Finally, we show that there exists an asymptotically valid (non-trivial) confidence region for a multivariate parameter $\theta_0$ if and only if there exists a (non-trivial) estimator with an asymptotic orthant median bias of zero.
The Health Index (HI) is crucial for evaluating system health, aiding tasks like anomaly detection and predicting remaining useful life for systems demanding high safety and reliability. Tight monitoring is crucial for achieving high precision at a lower cost, with applications such as spray coating. Obtaining HI labels in real-world applications is often cost-prohibitive, requiring continuous, precise health measurements. Therefore, it is more convenient to leverage run-to failure datasets that may provide potential indications of machine wear condition, making it necessary to apply semi-supervised tools for HI construction. In this study, we adapt the Deep Semi-supervised Anomaly Detection (DeepSAD) method for HI construction. We use the DeepSAD embedding as a condition indicators to address interpretability challenges and sensitivity to system-specific factors. Then, we introduce a diversity loss to enrich condition indicators. We employ an alternating projection algorithm with isotonic constraints to transform the DeepSAD embedding into a normalized HI with an increasing trend. Validation on the PHME 2010 milling dataset, a recognized benchmark with ground truth HIs demonstrates meaningful HIs estimations. Our methodology is then applied to monitor wear states of thermal spray coatings using high-frequency voltage. Our contributions create opportunities for more accessible and reliable HI estimation, particularly in cases where obtaining ground truth HI labels is unfeasible.
The detection of heterogeneous mental disorders based on brain readouts remains challenging due to the complexity of symptoms and the absence of reliable biomarkers. This paper introduces CAM (Cortical Anomaly Detection through Masked Image Modeling), a novel self-supervised framework designed for the unsupervised detection of complex brain disorders using cortical surface features. We employ this framework for the detection of individuals on the psychotic spectrum and demonstrate its capabilities compared to state-ofthe-art methods, achieving an AUC of 0.696 for Schizoaffective and 0.769 for Schizophreniform, without the need for any labels. Furthermore, the analysis of atypical cortical regions includes Pars Triangularis and several frontal areas, often implicated in schizophrenia, provide further confidence in our approach. Altogether, we demonstrate a scalable approach for anomaly detection of complex brain disorders based on cortical abnormalities.
Knowledge distillation (KD) emerges as a promising yet challenging technique for compressing deep neural networks, aiming to transfer extensive learning representations from proficient and computationally intensive teacher models to compact student models. However, current KD methods for super-resolution (SR) models have limited performance and restricted applications, since the characteristics of SR tasks are overlooked. In this paper, we put forth an approach from the perspective of effective data utilization, namely, the Data Upcycling Knowledge Distillation (DUKD), which facilitates the student model by the prior knowledge the teacher provided through the upcycled in-domain data derived from the input images. Besides, for the first time, we realize the label consistency regularization in KD for SR models, which is implemented by the paired invertible data augmentations. It constrains the training process of KD and leads to better generalization capability of the student model. The DUKD, due to its versatility, can be applied across a broad spectrum of teacher-student architectures (e.g., CNN and Transformer models) and SR tasks, such as single image SR, real-world SR, and SR quantization, and is in parallel with other compression techniques. Comprehensive experiments on diverse benchmarks demonstrate that the DUKD method significantly outperforms previous art.
Changes in speech and language are among the first signs of Parkinson's disease (PD). Thus, clinicians have tried to identify individuals with PD from their voices for years. Doctors can leverage AI-based speech assessments to spot PD thanks to advancements in artificial intelligence (AI). Such AI systems can be developed using machine learning classifiers that have been trained using individuals' voices. Although several studies have shown reasonable results in developing such AI systems, these systems would need more data samples to achieve promising performance. This paper explores using deep learning-based data generation techniques on the accuracy of machine learning classifiers that are the core of such systems.
Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue instances to learn as they fail to capture the correlations between different diseases and neglect the diagnostic experience shared among them. To address this issue, we propose a more natural and practical paradigm, i.e., low-resource medical dialogue generation, which can transfer the diagnostic experience from source diseases to target ones with a handful of data for adaptation. It is capitalized on a commonsense knowledge graph to characterize the prior disease-symptom relations. Besides, we develop a Graph-Evolving Meta-Learning (GEML) framework that learns to evolve the commonsense graph for reasoning disease-symptom correlations in a new disease, which effectively alleviates the needs of a large number of dialogues. More importantly, by dynamically evolving disease-symptom graphs, GEML also well addresses the real-world challenges that the disease-symptom correlations of each disease may vary or evolve along with more diagnostic cases. Extensive experiment results on the CMDD dataset and our newly-collected Chunyu dataset testify the superiority of our approach over state-of-the-art approaches. Besides, our GEML can generate an enriched dialogue-sensitive knowledge graph in an online manner, which could benefit other tasks grounded on knowledge graph.
Applying artificial intelligence techniques in medical imaging is one of the most promising areas in medicine. However, most of the recent success in this area highly relies on large amounts of carefully annotated data, whereas annotating medical images is a costly process. In this paper, we propose a novel method, called FocalMix, which, to the best of our knowledge, is the first to leverage recent advances in semi-supervised learning (SSL) for 3D medical image detection. We conducted extensive experiments on two widely used datasets for lung nodule detection, LUNA16 and NLST. Results show that our proposed SSL methods can achieve a substantial improvement of up to 17.3% over state-of-the-art supervised learning approaches with 400 unlabeled CT scans.
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