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D-Adaptation is an approach to automatically setting the learning rate which asymptotically achieves the optimal rate of convergence for minimizing convex Lipschitz functions, with no back-tracking or line searches, and no additional function value or gradient evaluations per step. Our approach is the first hyper-parameter free method for this class without additional multiplicative log factors in the convergence rate. We present extensive experiments for SGD and Adam variants of our method, where the method automatically matches hand-tuned learning rates across more than a dozen diverse machine learning problems, including large-scale vision and language problems. An open-source implementation is available.

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Decentralized federated learning (DFL) has gained popularity due to its practicality across various applications. Compared to the centralized version, training a shared model among a large number of nodes in DFL is more challenging, as there is no central server to coordinate the training process. Especially when distributed nodes suffer from limitations in communication or computational resources, DFL will experience extremely inefficient and unstable training. Motivated by these challenges, in this paper, we develop a novel algorithm based on the framework of the inexact alternating direction method (iADM). On one hand, our goal is to train a shared model with a sparsity constraint. This constraint enables us to leverage one-bit compressive sensing (1BCS), allowing transmission of one-bit information among neighbour nodes. On the other hand, communication between neighbour nodes occurs only at certain steps, reducing the number of communication rounds. Therefore, the algorithm exhibits notable communication efficiency. Additionally, as each node selects only a subset of neighbours to participate in the training, the algorithm is robust against stragglers. Additionally, complex items are computed only once for several consecutive steps and subproblems are solved inexactly using closed-form solutions, resulting in high computational efficiency. Finally, numerical experiments showcase the algorithm's effectiveness in both communication and computation.

Low-rank multivariate regression (LRMR) is an important statistical learning model that combines highly correlated tasks as a multiresponse regression problem with low-rank priori on the coefficient matrix. In this paper, we study quantized LRMR, a practical setting where the responses and/or the covariates are discretized to finite precision. We focus on the estimation of the underlying coefficient matrix. To make consistent estimator that could achieve arbitrarily small error possible, we employ uniform quantization with random dithering, i.e., we add appropriate random noise to the data before quantization. Specifically, uniform dither and triangular dither are used for responses and covariates, respectively. Based on the quantized data, we propose the constrained Lasso and regularized Lasso estimators, and derive the non-asymptotic error bounds. With the aid of dithering, the estimators achieve minimax optimal rate, while quantization only slightly worsens the multiplicative factor in the error rate. Moreover, we extend our results to a low-rank regression model with matrix responses. We corroborate and demonstrate our theoretical results via simulations on synthetic data or image restoration.

Bio-inspired learning has been gaining popularity recently given that Backpropagation (BP) is not considered biologically plausible. Many algorithms have been proposed in the literature which are all more biologically plausible than BP. However, apart from overcoming the biological implausibility of BP, a strong motivation for using Bio-inspired algorithms remains lacking. In this study, we undertake a holistic comparison of BP vs. multiple Bio-inspired algorithms to answer the question of whether Bio-learning offers additional benefits over BP. We test Bio-algorithms under different design choices such as access to only partial training data, resource constraints in terms of the number of training epochs, sparsification of the neural network parameters and addition of noise to input samples. Through these experiments, we notably find two key advantages of Bio-algorithms over BP. Firstly, Bio-algorithms perform much better than BP when the entire training dataset is not supplied. Four of the five Bio-algorithms tested outperform BP by upto 5% accuracy when only 20% of the training dataset is available. Secondly, even when the full dataset is available, Bio-algorithms learn much quicker and converge to a stable accuracy in far lesser training epochs than BP. Hebbian learning, specifically, is able to learn in just 5 epochs compared to around 100 epochs required by BP. These insights present practical reasons for utilising Bio-learning beyond just their biological plausibility and also point towards interesting new directions for future work on Bio-learning.

Generative Adversarial Networks (GANs) should produce synthetic data that fits the underlying distribution of the data being modeled. For real valued time-series data, this implies the need to simultaneously capture the static distribution of the data, but also the full temporal distribution of the data for any potential time horizon. This temporal element produces a more complex problem that can potentially leave current solutions under-constrained, unstable during training, or prone to varying degrees of mode collapse. In FETSGAN, entire sequences are translated directly to the generator's sampling space using a seq2seq style adversarial auto encoder (AAE), where adversarial training is used to match the training distribution in both the feature space and the lower dimensional sampling space. This additional constraint provides a loose assurance that the temporal distribution of the synthetic samples will not collapse. In addition, the First Above Threshold (FAT) operator is introduced to supplement the reconstruction of encoded sequences, which improves training stability and the overall quality of the synthetic data being generated. These novel contributions demonstrate a significant improvement to the current state of the art for adversarial learners in qualitative measures of temporal similarity and quantitative predictive ability of data generated through FETSGAN.

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem in which the large-scale image resolutions of WSIs and the enormous diversity of morphological phenotypes preclude large-scale data annotation. Current efforts have proposed using pretrained image encoders with either transfer learning from natural image datasets or self-supervised pretraining on publicly-available histopathology datasets, but have not been extensively developed and evaluated across diverse tissue types at scale. We introduce UNI, a general-purpose self-supervised model for pathology, pretrained using over 100 million tissue patches from over 100,000 diagnostic haematoxylin and eosin-stained WSIs across 20 major tissue types, and evaluated on 33 representative CPath clinical tasks in CPath of varying diagnostic difficulties. In addition to outperforming previous state-of-the-art models, we demonstrate new modeling capabilities in CPath such as resolution-agnostic tissue classification, slide classification using few-shot class prototypes, and disease subtyping generalization in classifying up to 108 cancer types in the OncoTree code classification system. UNI advances unsupervised representation learning at scale in CPath in terms of both pretraining data and downstream evaluation, enabling data-efficient AI models that can generalize and transfer to a gamut of diagnostically-challenging tasks and clinical workflows in anatomic pathology.

The assessment of the well-being of the peripheral auditory nerve system in individuals experiencing hearing impairment is conducted through auditory brainstem response (ABR) testing. Audiologists assess and document the results of the ABR test. They interpret the findings and assign labels to them using reference-based markers like peak latency, waveform morphology, amplitude, and other relevant factors. Inaccurate assessment of ABR tests may lead to incorrect judgments regarding the integrity of the auditory nerve system; therefore, proper Hearing Loss (HL) diagnosis and analysis are essential. To identify and assess ABR automation while decreasing the possibility of human error, machine learning methods, notably deep learning, may be an appropriate option. To address these issues, this study proposed deep-learning models using the transfer-learning (TL) approach to extract features from ABR testing and diagnose HL using support vector machines (SVM). Pre-trained convolutional neural network (CNN) architectures like AlexNet, DenseNet, GoogleNet, InceptionResNetV2, InceptionV3, MobileNetV2, NASNetMobile, ResNet18, ResNet50, ResNet101, ShuffleNet, and SqueezeNet are used to extract features from the collected ABR reported images dataset in the proposed model. It has been decided to use six measures accuracy, precision, recall, geometric mean (GM), standard deviation (SD), and area under the ROC curve to measure the effectiveness of the proposed model. According to experimental findings, the ShuffleNet and ResNet50 models' TL is effective for ABR to diagnose HL using an SVM classifier, with a high accuracy rate of 95% when using the 5-fold cross-validation method.

Standard contrastive learning approaches usually require a large number of negatives for effective unsupervised learning and often exhibit slow convergence. We suspect this behavior is due to the suboptimal selection of negatives used for offering contrast to the positives. We counter this difficulty by taking inspiration from support vector machines (SVMs) to present max-margin contrastive learning (MMCL). Our approach selects negatives as the sparse support vectors obtained via a quadratic optimization problem, and contrastiveness is enforced by maximizing the decision margin. As SVM optimization can be computationally demanding, especially in an end-to-end setting, we present simplifications that alleviate the computational burden. We validate our approach on standard vision benchmark datasets, demonstrating better performance in unsupervised representation learning over state-of-the-art, while having better empirical convergence properties.

Out-of-distribution (OOD) detection is critical to ensuring the reliability and safety of machine learning systems. For instance, in autonomous driving, we would like the driving system to issue an alert and hand over the control to humans when it detects unusual scenes or objects that it has never seen before and cannot make a safe decision. This problem first emerged in 2017 and since then has received increasing attention from the research community, leading to a plethora of methods developed, ranging from classification-based to density-based to distance-based ones. Meanwhile, several other problems are closely related to OOD detection in terms of motivation and methodology. These include anomaly detection (AD), novelty detection (ND), open set recognition (OSR), and outlier detection (OD). Despite having different definitions and problem settings, these problems often confuse readers and practitioners, and as a result, some existing studies misuse terms. In this survey, we first present a generic framework called generalized OOD detection, which encompasses the five aforementioned problems, i.e., AD, ND, OSR, OOD detection, and OD. Under our framework, these five problems can be seen as special cases or sub-tasks, and are easier to distinguish. Then, we conduct a thorough review of each of the five areas by summarizing their recent technical developments. We conclude this survey with open challenges and potential research directions.

Exploration-exploitation is a powerful and practical tool in multi-agent learning (MAL), however, its effects are far from understood. To make progress in this direction, we study a smooth analogue of Q-learning. We start by showing that our learning model has strong theoretical justification as an optimal model for studying exploration-exploitation. Specifically, we prove that smooth Q-learning has bounded regret in arbitrary games for a cost model that explicitly captures the balance between game and exploration costs and that it always converges to the set of quantal-response equilibria (QRE), the standard solution concept for games under bounded rationality, in weighted potential games with heterogeneous learning agents. In our main task, we then turn to measure the effect of exploration in collective system performance. We characterize the geometry of the QRE surface in low-dimensional MAL systems and link our findings with catastrophe (bifurcation) theory. In particular, as the exploration hyperparameter evolves over-time, the system undergoes phase transitions where the number and stability of equilibria can change radically given an infinitesimal change to the exploration parameter. Based on this, we provide a formal theoretical treatment of how tuning the exploration parameter can provably lead to equilibrium selection with both positive as well as negative (and potentially unbounded) effects to system performance.

Multi-relation Question Answering is a challenging task, due to the requirement of elaborated analysis on questions and reasoning over multiple fact triples in knowledge base. In this paper, we present a novel model called Interpretable Reasoning Network that employs an interpretable, hop-by-hop reasoning process for question answering. The model dynamically decides which part of an input question should be analyzed at each hop; predicts a relation that corresponds to the current parsed results; utilizes the predicted relation to update the question representation and the state of the reasoning process; and then drives the next-hop reasoning. Experiments show that our model yields state-of-the-art results on two datasets. More interestingly, the model can offer traceable and observable intermediate predictions for reasoning analysis and failure diagnosis, thereby allowing manual manipulation in predicting the final answer.

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