Neuroimage processing tasks like segmentation, reconstruction, and registration are central to the study of neuroscience. Robust deep learning strategies and architectures used to solve these tasks are often similar. Yet, when presented with a new task or a dataset with different visual characteristics, practitioners most often need to train a new model, or fine-tune an existing one. This is a time-consuming process that poses a substantial barrier for the thousands of neuroscientists and clinical researchers who often lack the resources or machine-learning expertise to train deep learning models. In practice, this leads to a lack of adoption of deep learning, and neuroscience tools being dominated by classical frameworks. We introduce Neuralizer, a single model that generalizes to previously unseen neuroimaging tasks and modalities without the need for re-training or fine-tuning. Tasks do not have to be known a priori, and generalization happens in a single forward pass during inference. The model can solve processing tasks across multiple image modalities, acquisition methods, and datasets, and generalize to tasks and modalities it has not been trained on. Our experiments on coronal slices show that when few annotated subjects are available, our multi-task network outperforms task-specific baselines without training on the task.
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Processing 是一門開源編程語言和與之配套的集成開發環境（IDE）的名(ming)稱。Processing 在電子藝術和視(shi)覺設(she)計(ji)社區被用來教授編程基礎，并(bing)運用于大量的新媒體和互動藝術作(zuo)品中。
Data efficiency, or the ability to generalize from a few labeled data, remains a major challenge in deep learning. Semi-supervised learning has thrived in traditional recognition tasks alleviating the need for large amounts of labeled data, yet it remains understudied in image-to-image translation (I2I) tasks. In this work, we introduce the first semi-supervised (semi-paired) framework for label-to-image translation, a challenging subtask of I2I which generates photorealistic images from semantic label maps. In the semi-paired setting, the model has access to a small set of paired data and a larger set of unpaired images and labels. Instead of using geometrical transformations as a pretext task like previous works, we leverage an input reconstruction task by exploiting the conditional discriminator on the paired data as a reverse generator. We propose a training algorithm for this shared network, and we present a rare classes sampling algorithm to focus on under-represented classes. Experiments on 3 standard benchmarks show that the proposed model outperforms state-of-the-art unsupervised and semi-supervised approaches, as well as some fully supervised approaches while using a much smaller number of paired samples.
We present DiffInfinite, a hierarchical diffusion model that generates arbitrarily large histological images while preserving long-range correlation structural information. Our approach first generates synthetic segmentation masks, subsequently used as conditions for the high-fidelity generative diffusion process. The proposed sampling method can be scaled up to any desired image size while only requiring small patches for fast training. Moreover, it can be parallelized more efficiently than previous large-content generation methods while avoiding tiling artefacts. The training leverages classifier-free guidance to augment a small, sparsely annotated dataset with unlabelled data. Our method alleviates unique challenges in histopathological imaging practice: large-scale information, costly manual annotation, and protective data handling. The biological plausibility of DiffInfinite data is validated in a survey by ten experienced pathologists as well as a downstream segmentation task. Furthermore, the model scores strongly on anti-copying metrics which is beneficial for the protection of patient data.
Long-term visual localization is an essential problem in robotics and computer vision, but remains challenging due to the environmental appearance changes caused by lighting and seasons. While many existing works have attempted to solve it by directly learning invariant sparse keypoints and descriptors to match scenes, these approaches still struggle with adverse appearance changes. Recent developments in image transformations such as neural style transfer have emerged as an alternative to address such appearance gaps. In this work, we propose to combine an image transformation network and a feature-learning network to improve long-term localization performance. Given night-to-day image pairs, the image transformation network transforms the night images into day-like conditions prior to feature matching; the feature network learns to detect keypoint locations with their associated descriptor values, which can be passed to a classical pose estimator to compute the relative poses. We conducted various experiments to examine the effectiveness of combining style transfer and feature learning and its training strategy, showing that such a combination greatly improves long-term localization performance.
While numerous methods exist to solve classification problems within curated datasets, these solutions often fall short in biomedical applications due to the biased or ambiguous nature of the data. These difficulties are particularly evident when inferring height reduction from vertebral data, a key component of the clinically-recognized Genant score. Although strategies such as semi-supervised learning, proposal usage, and class blending may provide some resolution, a clear and superior solution remains elusive. This paper introduces a flowchart of general strategy to address these issues. We demonstrate the application of this strategy by constructing a vertebral fracture dataset with over 300,000 annotations. This work facilitates the transition of the classification problem into clinically meaningful scores and enriches our understanding of vertebral height reduction.
Deep neural networks (DNNs) have found widespread applications in interpreting remote sensing (RS) imagery. However, it has been demonstrated in previous works that DNNs are vulnerable to different types of noises, particularly adversarial noises. Surprisingly, there has been a lack of comprehensive studies on the robustness of RS tasks, prompting us to undertake a thorough survey and benchmark on the robustness of image classification and object detection in RS. To our best knowledge, this study represents the first comprehensive examination of both natural robustness and adversarial robustness in RS tasks. Specifically, we have curated and made publicly available datasets that contain natural and adversarial noises. These datasets serve as valuable resources for evaluating the robustness of DNNs-based models. To provide a comprehensive assessment of model robustness, we conducted meticulous experiments with numerous different classifiers and detectors, encompassing a wide range of mainstream methods. Through rigorous evaluation, we have uncovered insightful and intriguing findings, which shed light on the relationship between adversarial noise crafting and model training, yielding a deeper understanding of the susceptibility and limitations of various models, and providing guidance for the development of more resilient and robust models
Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.
With the rise of powerful pre-trained vision-language models like CLIP, it becomes essential to investigate ways to adapt these models to downstream datasets. A recently proposed method named Context Optimization (CoOp) introduces the concept of prompt learning -- a recent trend in NLP -- to the vision domain for adapting pre-trained vision-language models. Specifically, CoOp turns context words in a prompt into a set of learnable vectors and, with only a few labeled images for learning, can achieve huge improvements over intensively-tuned manual prompts. In our study we identify a critical problem of CoOp: the learned context is not generalizable to wider unseen classes within the same dataset, suggesting that CoOp overfits base classes observed during training. To address the problem, we propose Conditional Context Optimization (CoCoOp), which extends CoOp by further learning a lightweight neural network to generate for each image an input-conditional token (vector). Compared to CoOp's static prompts, our dynamic prompts adapt to each instance and are thus less sensitive to class shift. Extensive experiments show that CoCoOp generalizes much better than CoOp to unseen classes, even showing promising transferability beyond a single dataset; and yields stronger domain generalization performance as well. Code is available at //github.com/KaiyangZhou/CoOp.
The time and effort involved in hand-designing deep neural networks is immense. This has prompted the development of Neural Architecture Search (NAS) techniques to automate this design. However, NAS algorithms tend to be slow and expensive; they need to train vast numbers of candidate networks to inform the search process. This could be alleviated if we could partially predict a network's trained accuracy from its initial state. In this work, we examine the overlap of activations between datapoints in untrained networks and motivate how this can give a measure which is usefully indicative of a network's trained performance. We incorporate this measure into a simple algorithm that allows us to search for powerful networks without any training in a matter of seconds on a single GPU, and verify its effectiveness on NAS-Bench-101, NAS-Bench-201, NATS-Bench, and Network Design Spaces. Our approach can be readily combined with more expensive search methods; we examine a simple adaptation of regularised evolutionary search. Code for reproducing our experiments is available at //github.com/BayesWatch/nas-without-training.
A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8% of benchmark performance using only two labeled MRI volumes for training, corresponding to only 4% (for ACDC) of the training data used to train the benchmark.
Image-to-image translation aims to learn the mapping between two visual domains. There are two main challenges for many applications: 1) the lack of aligned training pairs and 2) multiple possible outputs from a single input image. In this work, we present an approach based on disentangled representation for producing diverse outputs without paired training images. To achieve diversity, we propose to embed images onto two spaces: a domain-invariant content space capturing shared information across domains and a domain-specific attribute space. Our model takes the encoded content features extracted from a given input and the attribute vectors sampled from the attribute space to produce diverse outputs at test time. To handle unpaired training data, we introduce a novel cross-cycle consistency loss based on disentangled representations. Qualitative results show that our model can generate diverse and realistic images on a wide range of tasks without paired training data. For quantitative comparisons, we measure realism with user study and diversity with a perceptual distance metric. We apply the proposed model to domain adaptation and show competitive performance when compared to the state-of-the-art on the MNIST-M and the LineMod datasets.
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