We present USLR, a computational framework for longitudinal registration of brain MRI scans to estimate nonlinear image trajectories that are smooth across time, unbiased to any timepoint, and robust to imaging artefacts. It operates on the Lie algebra parameterisation of spatial transforms (which is compatible with rigid transforms and stationary velocity fields for nonlinear deformation) and takes advantage of log-domain properties to solve the problem using Bayesian inference. USRL estimates rigid and nonlinear registrations that: (i) bring all timepoints to an unbiased subject-specific space; and (i) compute a smooth trajectory across the imaging time-series. We capitalise on learning-based registration algorithms and closed-form expressions for fast inference. A use-case Alzheimer's disease study is used to showcase the benefits of the pipeline in multiple fronts, such as time-consistent image segmentation to reduce intra-subject variability, subject-specific prediction or population analysis using tensor-based morphometry. We demonstrate that such approach improves upon cross-sectional methods in identifying group differences, which can be helpful in detecting more subtle atrophy levels or in reducing sample sizes in clinical trials. The code is publicly available in //github.com/acasamitjana/uslr
Human trajectory forecasting is a critical challenge in fields such as robotics and autonomous driving. Due to the inherent uncertainty of human actions and intentions in real-world scenarios, various unexpected occurrences may arise. To uncover latent motion patterns in human behavior, we introduce a novel memory-based method, named Motion Pattern Priors Memory Network. Our method involves constructing a memory bank derived from clustered prior knowledge of motion patterns observed in the training set trajectories. We introduce an addressing mechanism to retrieve the matched pattern and the potential target distributions for each prediction from the memory bank, which enables the identification and retrieval of natural motion patterns exhibited by agents, subsequently using the target priors memory token to guide the diffusion model to generate predictions. Extensive experiments validate the effectiveness of our approach, achieving state-of-the-art trajectory prediction accuracy. The code will be made publicly available.
Far-field speech recognition is a challenging task that conventionally uses signal processing beamforming to attack noise and interference problem. But the performance has been found usually limited due to heavy reliance on environmental assumption. In this paper, we propose a unified multichannel far-field speech recognition system that combines the neural beamforming and transformer-based Listen, Spell, Attend (LAS) speech recognition system, which extends the end-to-end speech recognition system further to include speech enhancement. Such framework is then jointly trained to optimize the final objective of interest. Specifically, factored complex linear projection (fCLP) has been adopted to form the neural beamforming. Several pooling strategies to combine look directions are then compared in order to find the optimal approach. Moreover, information of the source direction is also integrated in the beamforming to explore the usefulness of source direction as a prior, which is usually available especially in multi-modality scenario. Experiments on different microphone array geometry are conducted to evaluate the robustness against spacing variance of microphone array. Large in-house databases are used to evaluate the effectiveness of the proposed framework and the proposed method achieve 19.26\% improvement when compared with a strong baseline.
Gradient-enhanced Kriging (GE-Kriging) is a well-established surrogate modelling technique for approximating expensive computational models. However, it tends to get impractical for high-dimensional problems due to the size of the inherent correlation matrix and the associated high-dimensional hyper-parameter tuning problem. To address these issues, a new method, called sliced GE-Kriging (SGE-Kriging), is developed in this paper for reducing both the size of the correlation matrix and the number of hyper-parameters. We first split the training sample set into multiple slices, and invoke Bayes' theorem to approximate the full likelihood function via a sliced likelihood function, in which multiple small correlation matrices are utilized to describe the correlation of the sample set rather than one large one. Then, we replace the original high-dimensional hyper-parameter tuning problem with a low-dimensional counterpart by learning the relationship between the hyper-parameters and the derivative-based global sensitivity indices. The performance of SGE-Kriging is finally validated by means of numerical experiments with several benchmarks and a high-dimensional aerodynamic modeling problem. The results show that the SGE-Kriging model features an accuracy and robustness that is comparable to the standard one but comes at much less training costs. The benefits are most evident for high-dimensional problems with tens of variables.
Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However, patch-level classification is preferable in applications where only a limited number of cases are available or when local prediction accuracy is critical. On the other hand, acquiring extensive datasets with localized labels for training is not feasible. In this paper, we propose a semi-supervised patch-level histopathological image classification model, named CLASS-M, that does not require extensively labeled datasets. CLASS-M is formed by two main parts: a contrastive learning module that uses separated Hematoxylin and Eosin images generated through an adaptive stain separation process, and a module with pseudo-labels using MixUp. We compare our model with other state-of-the-art models on two clear cell renal cell carcinoma datasets. We demonstrate that our CLASS-M model has the best performance on both datasets. Our code is available at github.com/BzhangURU/Paper_CLASS-M/tree/main
The growing demand for natural interactions with technology underscores the importance of achieving realistic touch sensations in digital environments. Realizing this goal highly depends on comprehensive databases of finger-surface interactions, which need further development. Here, we present SENS3, an extensive open-access repository of multisensory data acquired from fifty surfaces when two participants explored them with their fingertips through static contact, pressing, tapping, and sliding. SENS3 encompasses high-fidelity visual, audio, and haptic information recorded during these interactions, including videos, sounds, contact forces, torques, positions, accelerations, skin temperature, heat flux, and surface photographs. Additionally, it incorporates thirteen participants' psychophysical sensation ratings while exploring these surfaces freely. We anticipate that SENS3 will be valuable for advancing multisensory texture rendering, user experience development, and touch sensing in robotics.
The back-end module of Distributed Collaborative Simultaneous Localization and Mapping (DCSLAM) requires solving a nonlinear Pose Graph Optimization (PGO) under a distributed setting, also known as SE(d)-synchronization. Most existing distributed graph optimization algorithms employ a simple sequential partitioning scheme, which may result in unbalanced subgraph dimensions due to the different geographic locations of each robot, and hence imposes extra communication load. Moreover, the performance of current Riemannian optimization algorithms can be further accelerated. In this letter, we propose a novel distributed pose graph optimization algorithm combining multi-level partitioning with an accelerated Riemannian optimization method. Firstly, we employ the multi-level graph partitioning algorithm to preprocess the naive pose graph to formulate a balanced optimization problem. In addition, inspired by the accelerated coordinate descent method, we devise an Improved Riemannian Block Coordinate Descent (IRBCD) algorithm and the critical point obtained is globally optimal. Finally, we evaluate the effects of four common graph partitioning approaches on the correlation of the inter-subgraphs, and discover that the Highest scheme has the best partitioning performance. Also, we implement simulations to quantitatively demonstrate that our proposed algorithm outperforms the state-of-the-art distributed pose graph optimization protocols.
Despite increasing interest in the automatic detection of media frames in NLP, the problem is typically simplified as single-label classification and adopts a topic-like view on frames, evading modelling the broader document-level narrative. In this work, we revisit a widely used conceptualization of framing from the communication sciences which explicitly captures elements of narratives, including conflict and its resolution, and integrate it with the narrative framing of key entities in the story as heroes, victims or villains. We adapt an effective annotation paradigm that breaks a complex annotation task into a series of simpler binary questions, and present an annotated data set of English news articles, and a case study on the framing of climate change in articles from news outlets across the political spectrum. Finally, we explore automatic multi-label prediction of our frames with supervised and semi-supervised approaches, and present a novel retrieval-based method which is both effective and transparent in its predictions. We conclude with a discussion of opportunities and challenges for future work on document-level models of narrative framing.
Recently, graph neural networks have been gaining a lot of attention to simulate dynamical systems due to their inductive nature leading to zero-shot generalizability. Similarly, physics-informed inductive biases in deep-learning frameworks have been shown to give superior performance in learning the dynamics of physical systems. There is a growing volume of literature that attempts to combine these two approaches. Here, we evaluate the performance of thirteen different graph neural networks, namely, Hamiltonian and Lagrangian graph neural networks, graph neural ODE, and their variants with explicit constraints and different architectures. We briefly explain the theoretical formulation highlighting the similarities and differences in the inductive biases and graph architecture of these systems. We evaluate these models on spring, pendulum, gravitational, and 3D deformable solid systems to compare the performance in terms of rollout error, conserved quantities such as energy and momentum, and generalizability to unseen system sizes. Our study demonstrates that GNNs with additional inductive biases, such as explicit constraints and decoupling of kinetic and potential energies, exhibit significantly enhanced performance. Further, all the physics-informed GNNs exhibit zero-shot generalizability to system sizes an order of magnitude larger than the training system, thus providing a promising route to simulate large-scale realistic systems.
We present ResMLP, an architecture built entirely upon multi-layer perceptrons for image classification. It is a simple residual network that alternates (i) a linear layer in which image patches interact, independently and identically across channels, and (ii) a two-layer feed-forward network in which channels interact independently per patch. When trained with a modern training strategy using heavy data-augmentation and optionally distillation, it attains surprisingly good accuracy/complexity trade-offs on ImageNet. We will share our code based on the Timm library and pre-trained models.
Recent work pre-training Transformers with self-supervised objectives on large text corpora has shown great success when fine-tuned on downstream NLP tasks including text summarization. However, pre-training objectives tailored for abstractive text summarization have not been explored. Furthermore there is a lack of systematic evaluation across diverse domains. In this work, we propose pre-training large Transformer-based encoder-decoder models on massive text corpora with a new self-supervised objective. In PEGASUS, important sentences are removed/masked from an input document and are generated together as one output sequence from the remaining sentences, similar to an extractive summary. We evaluated our best PEGASUS model on 12 downstream summarization tasks spanning news, science, stories, instructions, emails, patents, and legislative bills. Experiments demonstrate it achieves state-of-the-art performance on all 12 downstream datasets measured by ROUGE scores. Our model also shows surprising performance on low-resource summarization, surpassing previous state-of-the-art results on 6 datasets with only 1000 examples. Finally we validated our results using human evaluation and show that our model summaries achieve human performance on multiple datasets.