CNNs, most notably the UNet, are the default architecture for biomedical segmentation. Transformer-based approaches, such as UNETR, have been proposed to replace them, benefiting from a global field of view, but suffering from larger runtimes and higher parameter counts. The recent Vision Mamba architecture offers a compelling alternative to transformers, also providing a global field of view, but at higher efficiency. Here, we introduce ViM-UNet, a novel segmentation architecture based on it and compare it to UNet and UNETR for two challenging microscopy instance segmentation tasks. We find that it performs similarly or better than UNet, depending on the task, and outperforms UNETR while being more efficient. Our code is open source and documented at //github.com/constantinpape/torch-em/blob/main/vimunet.md.
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Gaussian Splatting has garnered widespread attention due to its exceptional performance. Consequently, SLAM systems based on Gaussian Splatting have emerged, leveraging its capabilities for rapid real-time rendering and high-fidelity mapping. However, current Gaussian Splatting SLAM systems usually struggle with large scene representation and lack effective loop closure adjustments and scene generalization capabilities. To address these issues, we introduce NGM-SLAM, the first GS-SLAM system that utilizes neural radiance field submaps for progressive scene expression, effectively integrating the strengths of neural radiance fields and 3D Gaussian Splatting. We have developed neural implicit submaps as supervision and achieve high-quality scene expression and online loop closure adjustments through Gaussian rendering of fused submaps. Our results on multiple real-world scenes and large-scale scene datasets demonstrate that our method can achieve accurate gap filling and high-quality scene expression, supporting both monocular, stereo, and RGB-D inputs, and achieving state-of-the-art scene reconstruction and tracking performance.
Click-Through Rate (CTR) prediction holds a paramount position in recommender systems. The prevailing ID-based paradigm underperforms in cold-start scenarios due to the skewed distribution of feature frequency. Additionally, the utilization of a single modality fails to exploit the knowledge contained within textual features. Recent efforts have sought to mitigate these challenges by integrating Pre-trained Language Models (PLMs). They design hard prompts to structure raw features into text for each interaction and then apply PLMs for text processing. With external knowledge and reasoning capabilities, PLMs extract valuable information even in cases of sparse interactions. Nevertheless, compared to ID-based models, pure text modeling degrades the efficacy of collaborative filtering, as well as feature scalability and efficiency during both training and inference. To address these issues, we propose \textbf{C}ost-\textbf{E}fficient \textbf{L}anguage Model \textbf{A}lignment (\textbf{CELA}) for CTR prediction. CELA incorporates textual features and language models while preserving the collaborative filtering capabilities of ID-based models. This model-agnostic framework can be equipped with plug-and-play textual features, with item-level alignment enhancing the utilization of external information while maintaining training and inference efficiency. Through extensive offline experiments, CELA demonstrates superior performance compared to state-of-the-art methods. Furthermore, an online A/B test conducted on an industrial App recommender system showcases its practical effectiveness, solidifying the potential for real-world applications of CELA.
Text-guided image editing is widely needed in daily life, ranging from personal use to professional applications such as Photoshop. However, existing methods are either zero-shot or trained on an automatically synthesized dataset, which contains a high volume of noise. Thus, they still require lots of manual tuning to produce desirable outcomes in practice. To address this issue, we introduce MagicBrush (//osu-nlp-group.github.io/MagicBrush/), the first large-scale, manually annotated dataset for instruction-guided real image editing that covers diverse scenarios: single-turn, multi-turn, mask-provided, and mask-free editing. MagicBrush comprises over 10K manually annotated triplets (source image, instruction, target image), which supports trainining large-scale text-guided image editing models. We fine-tune InstructPix2Pix on MagicBrush and show that the new model can produce much better images according to human evaluation. We further conduct extensive experiments to evaluate current image editing baselines from multiple dimensions including quantitative, qualitative, and human evaluations. The results reveal the challenging nature of our dataset and the gap between current baselines and real-world editing needs.
Fraud detection remains a challenging task due to the complex and deceptive nature of fraudulent activities. Current approaches primarily concentrate on learning only one perspective of the graph: either the topological structure of the graph or the attributes of individual nodes. However, we conduct empirical studies to reveal that these two types of features, while nearly orthogonal, are each independently effective. As a result, previous methods can not fully capture the comprehensive characteristics of the fraud graph. To address this dilemma, we present a novel framework called Relation-Aware GNN with transFormer~(RAGFormer) which simultaneously embeds both semantic and topological features into a target node. The simple yet effective network consists of a semantic encoder, a topology encoder, and an attention fusion module. The semantic encoder utilizes Transformer to learn semantic features and node interactions across different relations. We introduce Relation-Aware GNN as the topology encoder to learn topological features and node interactions within each relation. These two complementary features are interleaved through an attention fusion module to support prediction by both orthogonal features. Extensive experiments on two popular public datasets demonstrate that RAGFormer achieves state-of-the-art performance. The significant improvement of RAGFormer in an industrial credit card fraud detection dataset further validates the applicability of our method in real-world business scenarios.
In SLAM (Simultaneous localization and mapping) problems, Pose Graph Optimization (PGO) is a technique to refine an initial estimate of a set of poses (positions and orientations) from a set of pairwise relative measurements. The optimization procedure can be negatively affected even by a single outlier measurement, with possible catastrophic and meaningless results. Although recent works on robust optimization aim to mitigate the presence of outlier measurements, robust solutions capable of handling large numbers of outliers are yet to come. This paper presents IPC, acronym for Incremental Probabilistic Consensus, a method that approximates the solution to the combinatorial problem of finding the maximally consistent set of measurements in an incremental fashion. It evaluates the consistency of each loop closure measurement through a consensus-based procedure, possibly applied to a subset of the global problem, where all previously integrated inlier measurements have veto power. We evaluated IPC on standard benchmarks against several state-of-the-art methods. Although it is simple and relatively easy to implement, IPC competes with or outperforms the other tested methods in handling outliers while providing online performances. We release with this paper an open-source implementation of the proposed method.
Artificial intelligence holds promise to fundamentally enhance healthcare. Developing an integrated many-to-many framework leveraging multimodal data for multiple tasks is essential to unifying modern medicine. We introduce M3H, an explainable Multimodal Multitask Machine Learning for Healthcare framework that consolidates learning from tabular, time-series, language, and vision data for supervised binary/multiclass classification, regression, and unsupervised clustering. M3H encompasses an unprecedented range of medical tasks and problem domains and consistently outperforms traditional single-task models by on average 11.6% across 40 disease diagnoses from 16 medical departments, three hospital operation forecasts, and one patient phenotyping task. It features a novel attention mechanism balancing self-exploitation (learning source-task), and cross-exploration (learning cross-tasks), and offers explainability through a proposed TIM score, shedding light on the dynamics of task learning interdependencies. Its adaptable architecture supports easy customization and integration of new data modalities and tasks, establishing it as a robust, scalable solution for advancing AI-driven healthcare systems.
The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize LLMs for general business contexts that aims to achieve three fundamental objectives simultaneously: (1) aligning conversational patterns, (2) integrating in-depth domain knowledge, and (3) embodying theory-driven soft skills and core principles. We design methodologies that combine domain-specific theory with Supervised Fine Tuning (SFT) to achieve these objectives simultaneously. We instantiate our proposed framework in the context of medical consultation. Specifically, we carefully construct a large volume of real doctors' consultation records and medical knowledge from multiple professional databases. Additionally, drawing on medical theory, we identify three soft skills and core principles of human doctors: professionalism, explainability, and emotional support, and design approaches to integrate these traits into LLMs. We demonstrate the feasibility of our framework using online experiments with thousands of real patients as well as evaluation by domain experts and consumers. Experimental results show that the customized LLM model substantially outperforms untuned base model in medical expertise as well as consumer satisfaction and trustworthiness, and it substantially reduces the gap between untuned LLMs and human doctors, elevating LLMs to the level of human experts. Additionally, we delve into the characteristics of textual consultation records and adopt interpretable machine learning techniques to identify what drives the performance gain. Finally, we showcase the practical value of our model through a decision support system designed to assist human doctors in a lab experiment.
Graph-based learning approaches, due to their ability to encode tissue/organ structure information, are increasingly favored for grading colorectal cancer histology images. Recent graph-based techniques involve dividing whole slide images (WSIs) into smaller or medium-sized patches, and then building graphs on each patch for direct use in training. This method, however, fails to capture the tissue structure information present in an entire WSI and relies on training from a significantly large dataset of image patches. In this paper, we propose a novel cell-to-patch graph convolutional network (C2P-GCN), which is a two-stage graph formation-based approach. In the first stage, it forms a patch-level graph based on the cell organization on each patch of a WSI. In the second stage, it forms an image-level graph based on a similarity measure between patches of a WSI considering each patch as a node of a graph. This graph representation is then fed into a multi-layer GCN-based classification network. Our approach, through its dual-phase graph construction, effectively gathers local structural details from individual patches and establishes a meaningful connection among all patches across a WSI. As C2P-GCN integrates the structural data of an entire WSI into a single graph, it allows our model to work with significantly fewer training data compared to the latest models for colorectal cancer. Experimental validation of C2P-GCN on two distinct colorectal cancer datasets demonstrates the effectiveness of our method.
Applying artificial intelligence techniques in medical imaging is one of the most promising areas in medicine. However, most of the recent success in this area highly relies on large amounts of carefully annotated data, whereas annotating medical images is a costly process. In this paper, we propose a novel method, called FocalMix, which, to the best of our knowledge, is the first to leverage recent advances in semi-supervised learning (SSL) for 3D medical image detection. We conducted extensive experiments on two widely used datasets for lung nodule detection, LUNA16 and NLST. Results show that our proposed SSL methods can achieve a substantial improvement of up to 17.3% over state-of-the-art supervised learning approaches with 400 unlabeled CT scans.
Knowledge graphs are important resources for many artificial intelligence tasks but often suffer from incompleteness. In this work, we propose to use pre-trained language models for knowledge graph completion. We treat triples in knowledge graphs as textual sequences and propose a novel framework named Knowledge Graph Bidirectional Encoder Representations from Transformer (KG-BERT) to model these triples. Our method takes entity and relation descriptions of a triple as input and computes scoring function of the triple with the KG-BERT language model. Experimental results on multiple benchmark knowledge graphs show that our method can achieve state-of-the-art performance in triple classification, link prediction and relation prediction tasks.
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