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In this paper, we introduce QuST-LLM, an innovative extension of QuPath that utilizes the capabilities of large language models (LLMs) to analyze and interpret spatial transcriptomics (ST) data. This tool effectively simplifies the intricate and high-dimensional nature of ST data by offering a comprehensive workflow that includes data loading, region selection, gene expression analysis, and functional annotation. QuST-LLM employs LLMs to transform complex ST data into understandable and detailed biological narratives based on gene ontology annotations, thereby significantly improving the interpretability of ST data. Consequently, users can interact with their own ST data using natural language. Hence, QuST-LLM provides researchers with a potent functionality to unravel the spatial and functional complexities of tissues, fostering novel insights and advancements in biomedical research.

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We present Knesset-DictaBERT, a large Hebrew language model fine-tuned on the Knesset Corpus, which comprises Israeli parliamentary proceedings. The model is based on the DictaBERT architecture and demonstrates significant improvements in understanding parliamentary language according to the MLM task. We provide a detailed evaluation of the model's performance, showing improvements in perplexity and accuracy over the baseline DictaBERT model.

Recent advances in Automated Theorem Proving have shown the effectiveness of leveraging a (large) language model that generates tactics (i.e. proof steps) to search through proof states. The current model, while trained solely on successful proof paths, faces a discrepancy at the inference stage, as it must sample and try various tactics at each proof state until finding success, unlike its training which does not incorporate learning from failed attempts. Intuitively, a tactic that leads to a failed search path would indicate that similar tactics should receive less attention during the following trials. In this paper, we demonstrate the benefit of training models that additionally learn from failed search paths. Facing the lack of such trial-and-error data in existing open-source theorem-proving datasets, we curate a dataset on intuitionistic propositional logic theorems and formalize it in Lean, such that we can reliably check the correctness of proofs. We compare our model trained on relatively short trial-and-error information (TrialMaster) with models trained only on the correct paths and discover that the former solves more unseen theorems with lower trial searches.

We introduce MIA-Bench, a new benchmark designed to evaluate multimodal large language models (MLLMs) on their ability to strictly adhere to complex instructions. Our benchmark comprises a diverse set of 400 image-prompt pairs, each crafted to challenge the models' compliance with layered instructions in generating accurate responses that satisfy specific requested patterns. Evaluation results from a wide array of state-of-the-art MLLMs reveal significant variations in performance, highlighting areas for improvement in instruction fidelity. Additionally, we create extra training data and explore supervised fine-tuning to enhance the models' ability to strictly follow instructions without compromising performance on other tasks. We hope this benchmark not only serves as a tool for measuring MLLM adherence to instructions, but also guides future developments in MLLM training methods.

Large language models (LLMs) and their fine-tuning techniques have demonstrated superior performance in various language understanding and generation tasks. This paper explores fine-tuning LLMs for stock return forecasting with financial newsflow. In quantitative investing, return forecasting is fundamental for subsequent tasks like stock picking, portfolio optimization, etc. We formulate the model to include text representation and forecasting modules. We propose to compare the encoder-only and decoder-only LLMs, considering they generate text representations in distinct ways. The impact of these different representations on forecasting performance remains an open question. Meanwhile, we compare two simple methods of integrating LLMs' token-level representations into the forecasting module. The experiments on real news and investment universes reveal that: (1) aggregated representations from LLMs' token-level embeddings generally produce return predictions that enhance the performance of long-only and long-short portfolios; (2) in the relatively large investment universe, the decoder LLMs-based prediction model leads to stronger portfolios, whereas in the small universes, there are no consistent winners. Among the three LLMs studied (DeBERTa, Mistral, Llama), Mistral performs more robustly across different universes; (3) return predictions derived from LLMs' text representations are a strong signal for portfolio construction, outperforming conventional sentiment scores.

Generative artificial intelligence (AI) and large language models (LLMs) have gained rapid popularity through publicly available tools such as ChatGPT. The adoption of LLMs for personal and professional use is fueled by the natural interactions between human users and computer applications such as ChatGPT, along with powerful summarization and text generation capabilities. Given the widespread use of such generative AI tools, in this work we investigate how these tools can be deployed in a non-safety critical, strategic traffic flow management setting. Specifically, we train an LLM, CHATATC, based on a large historical data set of Ground Delay Program (GDP) issuances, spanning 2000-2023 and consisting of over 80,000 GDP implementations, revisions, and cancellations. We test the query and response capabilities of CHATATC, documenting successes (e.g., providing correct GDP rates, durations, and reason) and shortcomings (e.g,. superlative questions). We also detail the design of a graphical user interface for future users to interact and collaborate with the CHATATC conversational agent.

Hallucination has been a major problem for large language models and remains a critical challenge when it comes to multimodality in which vision-language models (VLMs) have to deal with not just textual but also visual inputs. Despite rapid progress in VLMs, resources for evaluating and addressing multimodal hallucination are limited and mostly focused on evaluation. This work introduces HaloQuest, a novel visual question answering dataset that captures various aspects of multimodal hallucination such as false premises, insufficient contexts, and visual challenges. A novel idea from HaloQuest is to leverage synthetic images, apart from real ones, to enable dataset creation at scale. With over 7.7K examples spanning across a wide variety of categories, HaloQuest was designed to be both a challenging benchmark for VLMs and a fine-tuning dataset for advancing multimodal reasoning. Our experiments reveal that current models struggle with HaloQuest, with all open-source VLMs achieving below 36% accuracy. On the other hand, fine-tuning on HaloQuest significantly reduces hallucination rates while preserving performance on standard reasoning tasks. Our results discover that benchmarking with generated images is highly correlated (r=0.97) with real images. Last but not least, we propose a novel Auto-Eval mechanism that is highly correlated with human raters (r=0.99) for evaluating VLMs. In sum, this work makes concrete strides towards understanding, evaluating, and mitigating hallucination in VLMs, serving as an important step towards more reliable multimodal AI systems in the future.

In this paper, we present SPVLoc, a global indoor localization method that accurately determines the six-dimensional (6D) camera pose of a query image and requires minimal scene-specific prior knowledge and no scene-specific training. Our approach employs a novel matching procedure to localize the perspective camera's viewport, given as an RGB image, within a set of panoramic semantic layout representations of the indoor environment. The panoramas are rendered from an untextured 3D reference model, which only comprises approximate structural information about room shapes, along with door and window annotations. We demonstrate that a straightforward convolutional network structure can successfully achieve image-to-panorama and ultimately image-to-model matching. Through a viewport classification score, we rank reference panoramas and select the best match for the query image. Then, a 6D relative pose is estimated between the chosen panorama and query image. Our experiments demonstrate that this approach not only efficiently bridges the domain gap but also generalizes well to previously unseen scenes that are not part of the training data. Moreover, it achieves superior localization accuracy compared to the state of the art methods and also estimates more degrees of freedom of the camera pose. Our source code is publicly available at //fraunhoferhhi.github.io/spvloc .

Large language models (LLMs) have demonstrated great success in various fields, benefiting from their huge amount of parameters that store knowledge. However, LLMs still suffer from several key issues, such as hallucination problems, knowledge update issues, and lacking domain-specific expertise. The appearance of retrieval-augmented generation (RAG), which leverages an external knowledge database to augment LLMs, makes up those drawbacks of LLMs. This paper reviews all significant techniques of RAG, especially in the retriever and the retrieval fusions. Besides, tutorial codes are provided for implementing the representative techniques in RAG. This paper further discusses the RAG training, including RAG with/without datastore update. Then, we introduce the application of RAG in representative natural language processing tasks and industrial scenarios. Finally, this paper discusses the future directions and challenges of RAG for promoting its development.

Since the launch of ChatGPT, a powerful AI Chatbot developed by OpenAI, large language models (LLMs) have made significant advancements in both academia and industry, bringing about a fundamental engineering paradigm shift in many areas. While LLMs are powerful, it is also crucial to best use their power where "prompt'' plays a core role. However, the booming LLMs themselves, including excellent APIs like ChatGPT, have several inherent limitations: 1) temporal lag of training data, and 2) the lack of physical capabilities to perform external actions. Recently, we have observed the trend of utilizing prompt-based tools to better utilize the power of LLMs for downstream tasks, but a lack of systematic literature and standardized terminology, partly due to the rapid evolution of this field. Therefore, in this work, we survey related prompting tools and promote the concept of the "Prompting Framework" (PF), i.e. the framework for managing, simplifying, and facilitating interaction with large language models. We define the lifecycle of the PF as a hierarchical structure, from bottom to top, namely: Data Level, Base Level, Execute Level, and Service Level. We also systematically depict the overall landscape of the emerging PF field and discuss potential future research and challenges. To continuously track the developments in this area, we maintain a repository at //github.com/lxx0628/Prompting-Framework-Survey, which can be a useful resource sharing platform for both academic and industry in this field.

The emergence of large language models (LLMs) has substantially influenced natural language processing, demonstrating exceptional results across various tasks. In this study, we employ ``Introspective Tips" to facilitate LLMs in self-optimizing their decision-making. By introspectively examining trajectories, LLM refines its policy by generating succinct and valuable tips. Our method enhances the agent's performance in both few-shot and zero-shot learning situations by considering three essential scenarios: learning from the agent's past experiences, integrating expert demonstrations, and generalizing across diverse games. Importantly, we accomplish these improvements without fine-tuning the LLM parameters; rather, we adjust the prompt to generalize insights from the three aforementioned situations. Our framework not only supports but also emphasizes the advantage of employing LLM in in-contxt decision-making. Experiments involving over 100 games in TextWorld illustrate the superior performance of our approach.

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