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Artificial intelligence and machine learning are poised to disrupt PET imaging from bench to clinic. In this perspective we offer insights into how the technology could be applied to improve the design and synthesis of new radiopharmaceuticals for PET imaging, including identification of an optimal labeling approach as well as strategies for radiolabeling reaction optimization.

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機(ji)器(qi)學(xue)(xue)習(Machine Learning)是(shi)一個(ge)研(yan)(yan)究(jiu)(jiu)(jiu)計算(suan)學(xue)(xue)習方(fang)(fang)(fang)法的(de)國際論(lun)壇。該(gai)(gai)雜志(zhi)發表(biao)文章,報告廣(guang)泛的(de)學(xue)(xue)習方(fang)(fang)(fang)法應(ying)用(yong)于各種學(xue)(xue)習問(wen)題的(de)實(shi)質(zhi)性結(jie)果。該(gai)(gai)雜志(zhi)的(de)特色論(lun)文描(miao)述研(yan)(yan)究(jiu)(jiu)(jiu)的(de)問(wen)題和方(fang)(fang)(fang)法,應(ying)用(yong)研(yan)(yan)究(jiu)(jiu)(jiu)和研(yan)(yan)究(jiu)(jiu)(jiu)方(fang)(fang)(fang)法的(de)問(wen)題。有(you)關(guan)學(xue)(xue)習問(wen)題或方(fang)(fang)(fang)法的(de)論(lun)文通過實(shi)證(zheng)研(yan)(yan)究(jiu)(jiu)(jiu)、理(li)論(lun)分析或與(yu)心理(li)現象的(de)比較提(ti)供了堅實(shi)的(de)支持。應(ying)用(yong)論(lun)文展示(shi)了如何應(ying)用(yong)學(xue)(xue)習方(fang)(fang)(fang)法來解決重(zhong)要的(de)應(ying)用(yong)問(wen)題。研(yan)(yan)究(jiu)(jiu)(jiu)方(fang)(fang)(fang)法論(lun)文改進(jin)了機(ji)器(qi)學(xue)(xue)習的(de)研(yan)(yan)究(jiu)(jiu)(jiu)方(fang)(fang)(fang)法。所有(you)的(de)論(lun)文都以其(qi)他研(yan)(yan)究(jiu)(jiu)(jiu)人員可(ke)以驗證(zheng)或復制的(de)方(fang)(fang)(fang)式(shi)描(miao)述了支持證(zheng)據(ju)。論(lun)文還詳(xiang)細(xi)說明(ming)了學(xue)(xue)習的(de)組成(cheng)部分,并(bing)討論(lun)了關(guan)于知(zhi)識表(biao)示(shi)和性能任務的(de)假(jia)設。 官網地址:

Many powerful Artificial Intelligence (AI) techniques have been engineered with the goals of high performance and accuracy. Recently, AI algorithms have been integrated into diverse and real-world applications. It has become an important topic to explore the impact of AI on society from a people-centered perspective. Previous works in citizen science have identified methods of using AI to engage the public in research, such as sustaining participation, verifying data quality, classifying and labeling objects, predicting user interests, and explaining data patterns. These works investigated the challenges regarding how scientists design AI systems for citizens to participate in research projects at a large geographic scale in a generalizable way, such as building applications for citizens globally to participate in completing tasks. In contrast, we are interested in another area that receives significantly less attention: how scientists co-design AI systems "with" local communities to influence a particular geographical region, such as community-based participatory projects. Specifically, this article discusses the challenges of applying AI in Community Citizen Science, a framework to create social impact through community empowerment at an intensely place-based local scale. We provide insights in this under-explored area of focus to connect scientific research closely to social issues and citizen needs.

We live in momentous times. The science community is empowered with an arsenal of cosmic messengers to study the Universe in unprecedented detail. Gravitational waves, electromagnetic waves, neutrinos and cosmic rays cover a wide range of wavelengths and time scales. Combining and processing these datasets that vary in volume, speed and dimensionality requires new modes of instrument coordination, funding and international collaboration with a specialized human and technological infrastructure. In tandem with the advent of large-scale scientific facilities, the last decade has experienced an unprecedented transformation in computing and signal processing algorithms. The combination of graphics processing units, deep learning, and the availability of open source, high-quality datasets, have powered the rise of artificial intelligence. This digital revolution now powers a multi-billion dollar industry, with far-reaching implications in technology and society. In this chapter we describe pioneering efforts to adapt artificial intelligence algorithms to address computational grand challenges in Multi-Messenger Astrophysics. We review the rapid evolution of these disruptive algorithms, from the first class of algorithms introduced in early 2017, to the sophisticated algorithms that now incorporate domain expertise in their architectural design and optimization schemes. We discuss the importance of scientific visualization and extreme-scale computing in reducing time-to-insight and obtaining new knowledge from the interplay between models and data.

Human-in-the-loop aims to train an accurate prediction model with minimum cost by integrating human knowledge and experience. Humans can provide training data for machine learning applications and directly accomplish some tasks that are hard for computers in the pipeline with the help of machine-based approaches. In this paper, we survey existing works on human-in-the-loop from a data perspective and classify them into three categories with a progressive relationship: (1) the work of improving model performance from data processing, (2) the work of improving model performance through interventional model training, and (3) the design of the system independent human-in-the-loop. Using the above categorization, we summarize major approaches in the field, along with their technical strengths/ weaknesses, we have simple classification and discussion in natural language processing, computer vision, and others. Besides, we provide some open challenges and opportunities. This survey intends to provide a high-level summarization for human-in-the-loop and motivates interested readers to consider approaches for designing effective human-in-the-loop solutions.

Recent advances in sensor and mobile devices have enabled an unprecedented increase in the availability and collection of urban trajectory data, thus increasing the demand for more efficient ways to manage and analyze the data being produced. In this survey, we comprehensively review recent research trends in trajectory data management, ranging from trajectory pre-processing, storage, common trajectory analytic tools, such as querying spatial-only and spatial-textual trajectory data, and trajectory clustering. We also explore four closely related analytical tasks commonly used with trajectory data in interactive or real-time processing. Deep trajectory learning is also reviewed for the first time. Finally, we outline the essential qualities that a trajectory management system should possess in order to maximize flexibility.

We present a continuous formulation of machine learning, as a problem in the calculus of variations and differential-integral equations, very much in the spirit of classical numerical analysis and statistical physics. We demonstrate that conventional machine learning models and algorithms, such as the random feature model, the shallow neural network model and the residual neural network model, can all be recovered as particular discretizations of different continuous formulations. We also present examples of new models, such as the flow-based random feature model, and new algorithms, such as the smoothed particle method and spectral method, that arise naturally from this continuous formulation. We discuss how the issues of generalization error and implicit regularization can be studied under this framework.

The demand for artificial intelligence has grown significantly over the last decade and this growth has been fueled by advances in machine learning techniques and the ability to leverage hardware acceleration. However, in order to increase the quality of predictions and render machine learning solutions feasible for more complex applications, a substantial amount of training data is required. Although small machine learning models can be trained with modest amounts of data, the input for training larger models such as neural networks grows exponentially with the number of parameters. Since the demand for processing training data has outpaced the increase in computation power of computing machinery, there is a need for distributing the machine learning workload across multiple machines, and turning the centralized into a distributed system. These distributed systems present new challenges, first and foremost the efficient parallelization of the training process and the creation of a coherent model. This article provides an extensive overview of the current state-of-the-art in the field by outlining the challenges and opportunities of distributed machine learning over conventional (centralized) machine learning, discussing the techniques used for distributed machine learning, and providing an overview of the systems that are available.

Machine learning techniques have deeply rooted in our everyday life. However, since it is knowledge- and labor-intensive to pursue good learning performance, human experts are heavily involved in every aspect of machine learning. In order to make machine learning techniques easier to apply and reduce the demand for experienced human experts, automated machine learning (AutoML) has emerged as a hot topic with both industrial and academic interest. In this paper, we provide an up to date survey on AutoML. First, we introduce and define the AutoML problem, with inspiration from both realms of automation and machine learning. Then, we propose a general AutoML framework that not only covers most existing approaches to date but also can guide the design for new methods. Subsequently, we categorize and review the existing works from two aspects, i.e., the problem setup and the employed techniques. Finally, we provide a detailed analysis of AutoML approaches and explain the reasons underneath their successful applications. We hope this survey can serve as not only an insightful guideline for AutoML beginners but also an inspiration for future research.

Deep reinforcement learning is the combination of reinforcement learning (RL) and deep learning. This field of research has been able to solve a wide range of complex decision-making tasks that were previously out of reach for a machine. Thus, deep RL opens up many new applications in domains such as healthcare, robotics, smart grids, finance, and many more. This manuscript provides an introduction to deep reinforcement learning models, algorithms and techniques. Particular focus is on the aspects related to generalization and how deep RL can be used for practical applications. We assume the reader is familiar with basic machine learning concepts.

Deep learning (DL) is a high dimensional data reduction technique for constructing high-dimensional predictors in input-output models. DL is a form of machine learning that uses hierarchical layers of latent features. In this article, we review the state-of-the-art of deep learning from a modeling and algorithmic perspective. We provide a list of successful areas of applications in Artificial Intelligence (AI), Image Processing, Robotics and Automation. Deep learning is predictive in its nature rather then inferential and can be viewed as a black-box methodology for high-dimensional function estimation.

Our experience of the world is multimodal - we see objects, hear sounds, feel texture, smell odors, and taste flavors. Modality refers to the way in which something happens or is experienced and a research problem is characterized as multimodal when it includes multiple such modalities. In order for Artificial Intelligence to make progress in understanding the world around us, it needs to be able to interpret such multimodal signals together. Multimodal machine learning aims to build models that can process and relate information from multiple modalities. It is a vibrant multi-disciplinary field of increasing importance and with extraordinary potential. Instead of focusing on specific multimodal applications, this paper surveys the recent advances in multimodal machine learning itself and presents them in a common taxonomy. We go beyond the typical early and late fusion categorization and identify broader challenges that are faced by multimodal machine learning, namely: representation, translation, alignment, fusion, and co-learning. This new taxonomy will enable researchers to better understand the state of the field and identify directions for future research.

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