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Biomedical Engineering's Internet of Medical Things (IoMT) is helping to improve the accuracy, dependability, and productivity of electronic equipment in the healthcare business. Real-time sensory data from patients may be delivered and subsequently analyzed through rapid development of wearable IoMT devices, such as neuro-stimulation devices with a range of functions. Data from the Internet of Things is gathered, analyzed, and stored in a single location. However, single-point failure, data manipulation, privacy difficulties, and other challenges might arise as a result of centralization. Due to its decentralized nature, blockchain (BC) can alleviate these issues. The viability of establishing a non-invasive remote neurostimulation system employing IoMT-based transcranial Direct Current Stimulation is investigated in this work (tDCS). A hardware-based prototype tDCS device has been developed that can be operated over the internet using an android application. Our suggested framework addresses the problems of IoMTBC-based systems, meets the criteria of real-time remote patient monitoring systems, and incorporates literature best practices in the relevant fields.

Single image super-resolution (SISR) is a challenging ill-posed problem that aims to up-sample a given low-resolution (LR) image to a high-resolution (HR) counterpart. Due to the difficulty in obtaining real LR-HR training pairs, recent approaches are trained on simulated LR images degraded by simplified down-sampling operators, e.g., bicubic. Such an approach can be problematic in practice because of the large gap between the synthesized and real-world LR images. To alleviate the issue, we propose a novel Invertible scale-Conditional Function (ICF), which can scale an input image and then restore the original input with different scale conditions. By leveraging the proposed ICF, we construct a novel self-supervised SISR framework (ICF-SRSR) to handle the real-world SR task without using any paired/unpaired training data. Furthermore, our ICF-SRSR can generate realistic and feasible LR-HR pairs, which can make existing supervised SISR networks more robust. Extensive experiments demonstrate the effectiveness of the proposed method in handling SISR in a fully self-supervised manner. Our ICF-SRSR demonstrates superior performance compared to the existing methods trained on synthetic paired images in real-world scenarios and exhibits comparable performance compared to state-of-the-art supervised/unsupervised methods on public benchmark datasets.

Medical image segmentation methods often rely on fully supervised approaches to achieve excellent performance, which is contingent upon having an extensive set of labeled images for training. However, annotating medical images is both expensive and time-consuming. Semi-supervised learning offers a solution by leveraging numerous unlabeled images alongside a limited set of annotated ones. In this paper, we introduce a semi-supervised medical image segmentation method based on the mean-teacher model, referred to as Dual-Decoder Consistency via Pseudo-Labels Guided Data Augmentation (DCPA). This method combines consistency regularization, pseudo-labels, and data augmentation to enhance the efficacy of semi-supervised segmentation. Firstly, the proposed model comprises both student and teacher models with a shared encoder and two distinct decoders employing different up-sampling strategies. Minimizing the output discrepancy between decoders enforces the generation of consistent representations, serving as regularization during student model training. Secondly, we introduce mixup operations to blend unlabeled data with labeled data, creating mixed data and thereby achieving data augmentation. Lastly, pseudo-labels are generated by the teacher model and utilized as labels for mixed data to compute unsupervised loss. We compare the segmentation results of the DCPA model with six state-of-the-art semi-supervised methods on three publicly available medical datasets. Beyond classical 10\% and 20\% semi-supervised settings, we investigate performance with less supervision (5\% labeled data). Experimental outcomes demonstrate that our approach consistently outperforms existing semi-supervised medical image segmentation methods across the three semi-supervised settings.

The assessment of regression models with discrete outcomes is challenging and has many fundamental issues. With discrete outcomes, standard regression model assessment tools such as Pearson and deviance residuals do not follow the conventional reference distribution (normal) under the true model, calling into question the legitimacy of model assessment based on these tools. To fill this gap, we construct a new type of residuals for general discrete outcomes, including ordinal and count outcomes. The proposed residuals are based on two layers of probability integral transformation. When at least one continuous covariate is available, the proposed residuals closely follow a uniform distribution (a normal distribution after transformation) under the correctly specified model. One can construct visualizations such as QQ plots to check the overall fit of a model straightforwardly, and the shape of QQ plots can further help identify possible causes of misspecification such as overdispersion. We provide theoretical justification for the proposed residuals by establishing their asymptotic properties. Moreover, in order to assess the mean structure and identify potential covariates, we develop an ordered curve as a supplementary tool, which is based on the comparison between the partial sum of outcomes and of fitted means. Through simulation, we demonstrate empirically that the proposed tools outperform commonly used residuals for various model assessment tasks. We also illustrate the workflow of model assessment using the proposed tools in data analysis.

Pose-free neural radiance fields (NeRF) aim to train NeRF with unposed multi-view images and it has achieved very impressive success in recent years. Most existing works share the pipeline of training a coarse pose estimator with rendered images at first, followed by a joint optimization of estimated poses and neural radiance field. However, as the pose estimator is trained with only rendered images, the pose estimation is usually biased or inaccurate for real images due to the domain gap between real images and rendered images, leading to poor robustness for the pose estimation of real images and further local minima in joint optimization. We design IR-NeRF, an innovative pose-free NeRF that introduces implicit pose regularization to refine pose estimator with unposed real images and improve the robustness of the pose estimation for real images. With a collection of 2D images of a specific scene, IR-NeRF constructs a scene codebook that stores scene features and captures the scene-specific pose distribution implicitly as priors. Thus, the robustness of pose estimation can be promoted with the scene priors according to the rationale that a 2D real image can be well reconstructed from the scene codebook only when its estimated pose lies within the pose distribution. Extensive experiments show that IR-NeRF achieves superior novel view synthesis and outperforms the state-of-the-art consistently across multiple synthetic and real datasets.

Recently, graph neural networks (GNNs) have been widely used for document classification. However, most existing methods are based on static word co-occurrence graphs without sentence-level information, which poses three challenges:(1) word ambiguity, (2) word synonymity, and (3) dynamic contextual dependency. To address these challenges, we propose a novel GNN-based sparse structure learning model for inductive document classification. Specifically, a document-level graph is initially generated by a disjoint union of sentence-level word co-occurrence graphs. Our model collects a set of trainable edges connecting disjoint words between sentences and employs structure learning to sparsely select edges with dynamic contextual dependencies. Graphs with sparse structures can jointly exploit local and global contextual information in documents through GNNs. For inductive learning, the refined document graph is further fed into a general readout function for graph-level classification and optimization in an end-to-end manner. Extensive experiments on several real-world datasets demonstrate that the proposed model outperforms most state-of-the-art results, and reveal the necessity to learn sparse structures for each document.

Graph Neural Networks (GNNs) are widely used for analyzing graph-structured data. Most GNN methods are highly sensitive to the quality of graph structures and usually require a perfect graph structure for learning informative embeddings. However, the pervasiveness of noise in graphs necessitates learning robust representations for real-world problems. To improve the robustness of GNN models, many studies have been proposed around the central concept of Graph Structure Learning (GSL), which aims to jointly learn an optimized graph structure and corresponding representations. Towards this end, in the presented survey, we broadly review recent progress of GSL methods for learning robust representations. Specifically, we first formulate a general paradigm of GSL, and then review state-of-the-art methods classified by how they model graph structures, followed by applications that incorporate the idea of GSL in other graph tasks. Finally, we point out some issues in current studies and discuss future directions.

Translational distance-based knowledge graph embedding has shown progressive improvements on the link prediction task, from TransE to the latest state-of-the-art RotatE. However, N-1, 1-N and N-N predictions still remain challenging. In this work, we propose a novel translational distance-based approach for knowledge graph link prediction. The proposed method includes two-folds, first we extend the RotatE from 2D complex domain to high dimension space with orthogonal transforms to model relations for better modeling capacity. Second, the graph context is explicitly modeled via two directed context representations. These context representations are used as part of the distance scoring function to measure the plausibility of the triples during training and inference. The proposed approach effectively improves prediction accuracy on the difficult N-1, 1-N and N-N cases for knowledge graph link prediction task. The experimental results show that it achieves better performance on two benchmark data sets compared to the baseline RotatE, especially on data set (FB15k-237) with many high in-degree connection nodes.

Answering questions that require reading texts in an image is challenging for current models. One key difficulty of this task is that rare, polysemous, and ambiguous words frequently appear in images, e.g., names of places, products, and sports teams. To overcome this difficulty, only resorting to pre-trained word embedding models is far from enough. A desired model should utilize the rich information in multiple modalities of the image to help understand the meaning of scene texts, e.g., the prominent text on a bottle is most likely to be the brand. Following this idea, we propose a novel VQA approach, Multi-Modal Graph Neural Network (MM-GNN). It first represents an image as a graph consisting of three sub-graphs, depicting visual, semantic, and numeric modalities respectively. Then, we introduce three aggregators which guide the message passing from one graph to another to utilize the contexts in various modalities, so as to refine the features of nodes. The updated nodes have better features for the downstream question answering module. Experimental evaluations show that our MM-GNN represents the scene texts better and obviously facilitates the performances on two VQA tasks that require reading scene texts.

Visual Question Answering (VQA) models have struggled with counting objects in natural images so far. We identify a fundamental problem due to soft attention in these models as a cause. To circumvent this problem, we propose a neural network component that allows robust counting from object proposals. Experiments on a toy task show the effectiveness of this component and we obtain state-of-the-art accuracy on the number category of the VQA v2 dataset without negatively affecting other categories, even outperforming ensemble models with our single model. On a difficult balanced pair metric, the component gives a substantial improvement in counting over a strong baseline by 6.6%.