Decoding the human brain has been a hallmark of neuroscientists and Artificial Intelligence researchers alike. Reconstruction of visual images from brain Electroencephalography (EEG) signals has garnered a lot of interest due to its applications in brain-computer interfacing. This study proposes a two-stage method where the first step is to obtain EEG-derived features for robust learning of deep representations and subsequently utilize the learned representation for image generation and classification. We demonstrate the generalizability of our feature extraction pipeline across three different datasets using deep-learning architectures with supervised and contrastive learning methods. We have performed the zero-shot EEG classification task to support the generalizability claim further. We observed that a subject invariant linearly separable visual representation was learned using EEG data alone in an unimodal setting that gives better k-means accuracy as compared to a joint representation learning between EEG and images. Finally, we propose a novel framework to transform unseen images into the EEG space and reconstruct them with approximation, showcasing the potential for image reconstruction from EEG signals. Our proposed image synthesis method from EEG shows 62.9% and 36.13% inception score improvement on the EEGCVPR40 and the Thoughtviz datasets, which is better than state-of-the-art performance in GAN.
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The emergence of ChatGPT has once again sparked research in generative artificial intelligence (GAI). While people have been amazed by the generated results, they have also noticed the reasoning potential reflected in the generated textual content. However, this current ability for causal reasoning is primarily limited to the domain of language generation, such as in models like GPT-3. In visual modality, there is currently no equivalent research. Considering causal reasoning in visual content generation is significant. This is because visual information contains infinite granularity. Particularly, images can provide more intuitive and specific demonstrations for certain reasoning tasks, especially when compared to coarse-grained text. Hence, we propose a new image generation task called visual question answering with image (VQAI) and establish a dataset of the same name based on the classic \textit{Tom and Jerry} animated series. Additionally, we develop a new paradigm for image generation to tackle the challenges of this task. Finally, we perform extensive experiments and analyses, including visualizations of the generated content and discussions on the potentials and limitations. The code and data are publicly available under the license of CC BY-NC-SA 4.0 for academic and non-commercial usage. The code and dataset are publicly available at: //github.com/IEIT-AGI/MIX-Shannon/blob/main/projects/VQAI/lgd_vqai.md.
With the escalating complexity and volume of genomic data, the capacity of biology institutions' HPC faces limitations. While the Cloud presents a viable solution for short-term elasticity, its intricacies pose challenges for bioinformatics users. Alternatively, serverless computing allows for workload scalability with minimal developer burden. However, porting a scientific application to serverless is not a straightforward process. In this article, we present a Variant Calling genomics pipeline migrated from single-node HPC to a serverless architecture. We describe the inherent challenges of this approach and the engineering efforts required to achieve scalability. We contribute by open-sourcing the pipeline for future systems research and as a scalable user-friendly tool for the bioinformatics community.
The Spiking Neural Network (SNN), as one of the biologically inspired neural network infrastructures, has drawn increasing attention recently. It adopts binary spike activations to transmit information, thus the multiplications of activations and weights can be substituted by additions, which brings high energy efficiency. However, in the paper, we theoretically and experimentally prove that the binary spike activation map cannot carry enough information, thus causing information loss and resulting in accuracy decreasing. To handle the problem, we propose a ternary spike neuron to transmit information. The ternary spike neuron can also enjoy the event-driven and multiplication-free operation advantages of the binary spike neuron but will boost the information capacity. Furthermore, we also embed a trainable factor in the ternary spike neuron to learn the suitable spike amplitude, thus our SNN will adopt different spike amplitudes along layers, which can better suit the phenomenon that the membrane potential distributions are different along layers. To retain the efficiency of the vanilla ternary spike, the trainable ternary spike SNN will be converted to a standard one again via a re-parameterization technique in the inference. Extensive experiments with several popular network structures over static and dynamic datasets show that the ternary spike can consistently outperform state-of-the-art methods. Our code is open-sourced at //github.com/yfguo91/Ternary-Spike.
Multiple robot systems are favored for object manipulation and transportation, especially for large objects. However, in more complex manipulation such as flipping, these systems encounter a new challenge, configuration disconnectivity of manipulators. Grasping objects by manipulators will impose closed-chain constraints on the system, which in turn limits the feasible motions of manipulators and further compromises the configuration connectivity. Multiple mobile manipulator systems show much more flexibility in object manipulation with the mobility of the mobile platform and have the potential to address the above problem. In this paper, a novel planning framework is proposed for complex flipping manipulation by incorporating platform motions and regrasping. Firstly, two types of trajectories, mobile manipulator planning and regrasping planning, are classified and can be assigned different priorities for different tasks. Secondly, corresponding planning methods are designed for each type of trajectory. Specifically, in mobile manipulator planning, the configuration of the platform is determined through optimization to ensure connectivity when the manipulator approaches configuration boundaries. In regrasping planning, closed-chain constraints are temporarily disregarded and the manipulation capabilities are prioritized to facilitate subsequent planning. Finally, the structure of the overall planning framework is provided. Experimental results demonstrate that the proposed planner efficiently plans the motions of the system to accomplish flipping manipulation. Additionally, a comprehensive experiment emphasizes the significance of our planner in extending the capabilities of multiple mobile manipulator systems in complex tasks.
Learning from human preferences is crucial for language models (LMs) to effectively cater to human needs and societal values. Previous research has made notable progress by leveraging human feedback to follow instructions. However, these approaches rely primarily on online learning techniques like Proximal Policy Optimization (PPO), which have been proven unstable and challenging to tune for language models. Moreover, PPO requires complex distributed system implementation, hindering the efficiency of large-scale distributed training. In this study, we propose an offline learning from human feedback framework to align LMs without interacting with environments. Specifically, we explore filtering alignment (FA), reward-weighted regression (RWR), and conditional alignment (CA) to align language models to human preferences. By employing a loss function similar to supervised fine-tuning, our methods ensure more stable model training than PPO with a simple machine learning system~(MLSys) and much fewer (around 9\%) computing resources. Experimental results demonstrate that conditional alignment outperforms other offline alignment methods and is comparable to PPO.
Large Language Models have difficulty communicating uncertainty, which is a significant obstacle to applying LLMs to complex medical tasks. This study evaluates methods to measure LLM confidence when suggesting a diagnosis for challenging clinical vignettes. GPT4 was asked a series of challenging case questions using Chain of Thought and Self Consistency prompting. Multiple methods were investigated to assess model confidence and evaluated on their ability to predict the models observed accuracy. The methods evaluated were Intrinsic Confidence, SC Agreement Frequency and CoT Response Length. SC Agreement Frequency correlated with observed accuracy, yielding a higher Area under the Receiver Operating Characteristic Curve compared to Intrinsic Confidence and CoT Length analysis. SC agreement is the most useful proxy for model confidence, especially for medical diagnosis. Model Intrinsic Confidence and CoT Response Length exhibit a weaker ability to differentiate between correct and incorrect answers, preventing them from being reliable and interpretable markers for model confidence. We conclude GPT4 has a limited ability to assess its own diagnostic accuracy. SC Agreement Frequency is the most useful method to measure GPT4 confidence.
Improving neural machine translation (NMT) systems with prompting has achieved significant progress in recent years. In this work, we focus on how to integrate multi-knowledge, multiple types of knowledge, into NMT models to enhance the performance with prompting. We propose a unified framework, which can integrate effectively multiple types of knowledge including sentences, terminologies/phrases and translation templates into NMT models. We utilize multiple types of knowledge as prefix-prompts of input for the encoder and decoder of NMT models to guide the translation process. The approach requires no changes to the model architecture and effectively adapts to domain-specific translation without retraining. The experiments on English-Chinese and English-German translation demonstrate that our approach significantly outperform strong baselines, achieving high translation quality and terminology match accuracy.
Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to physicians has long been viewed as one such grand challenge. Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67.2% on the MedQA dataset. However, this and other prior work suggested significant room for improvement, especially when models' answers were compared to clinicians' answers. Here we present Med-PaLM 2, which bridges these gaps by leveraging a combination of base LLM improvements (PaLM 2), medical domain finetuning, and prompting strategies including a novel ensemble refinement approach. Med-PaLM 2 scored up to 86.5% on the MedQA dataset, improving upon Med-PaLM by over 19% and setting a new state-of-the-art. We also observed performance approaching or exceeding state-of-the-art across MedMCQA, PubMedQA, and MMLU clinical topics datasets. We performed detailed human evaluations on long-form questions along multiple axes relevant to clinical applications. In pairwise comparative ranking of 1066 consumer medical questions, physicians preferred Med-PaLM 2 answers to those produced by physicians on eight of nine axes pertaining to clinical utility (p < 0.001). We also observed significant improvements compared to Med-PaLM on every evaluation axis (p < 0.001) on newly introduced datasets of 240 long-form "adversarial" questions to probe LLM limitations. While further studies are necessary to validate the efficacy of these models in real-world settings, these results highlight rapid progress towards physician-level performance in medical question answering.
We consider the problem of explaining the predictions of graph neural networks (GNNs), which otherwise are considered as black boxes. Existing methods invariably focus on explaining the importance of graph nodes or edges but ignore the substructures of graphs, which are more intuitive and human-intelligible. In this work, we propose a novel method, known as SubgraphX, to explain GNNs by identifying important subgraphs. Given a trained GNN model and an input graph, our SubgraphX explains its predictions by efficiently exploring different subgraphs with Monte Carlo tree search. To make the tree search more effective, we propose to use Shapley values as a measure of subgraph importance, which can also capture the interactions among different subgraphs. To expedite computations, we propose efficient approximation schemes to compute Shapley values for graph data. Our work represents the first attempt to explain GNNs via identifying subgraphs explicitly and directly. Experimental results show that our SubgraphX achieves significantly improved explanations, while keeping computations at a reasonable level.
Recently, a considerable literature has grown up around the theme of Graph Convolutional Network (GCN). How to effectively leverage the rich structural information in complex graphs, such as knowledge graphs with heterogeneous types of entities and relations, is a primary open challenge in the field. Most GCN methods are either restricted to graphs with a homogeneous type of edges (e.g., citation links only), or focusing on representation learning for nodes only instead of jointly propagating and updating the embeddings of both nodes and edges for target-driven objectives. This paper addresses these limitations by proposing a novel framework, namely the Knowledge Embedding based Graph Convolutional Network (KE-GCN), which combines the power of GCNs in graph-based belief propagation and the strengths of advanced knowledge embedding (a.k.a. knowledge graph embedding) methods, and goes beyond. Our theoretical analysis shows that KE-GCN offers an elegant unification of several well-known GCN methods as specific cases, with a new perspective of graph convolution. Experimental results on benchmark datasets show the advantageous performance of KE-GCN over strong baseline methods in the tasks of knowledge graph alignment and entity classification.
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