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This paper presents a new framework for human body part segmentation based on Deep Convolutional Neural Networks trained using only synthetic data. The proposed approach achieves cutting-edge results without the need of training the models with real annotated data of human body parts. Our contributions include a data generation pipeline, that exploits a game engine for the creation of the synthetic data used for training the network, and a novel pre-processing module, that combines edge response maps and adaptive histogram equalization to guide the network to learn the shape of the human body parts ensuring robustness to changes in the illumination conditions. For selecting the best candidate architecture, we perform exhaustive tests on manually annotated images of real human body limbs. We further compare our method against several high-end commercial segmentation tools on the body parts segmentation task. The results show that our method outperforms the other models by a significant margin. Finally, we present an ablation study to validate our pre-processing module. With this paper, we release an implementation of the proposed approach along with the acquired datasets.

State-of-the-art computer vision models are mostly trained with supervised learning using human-labeled images, which limits their scalability due to the expensive annotation cost. While self-supervised representation learning has achieved impressive progress, it still requires a second stage of finetuning on labeled data. On the other hand, models pre-trained with large-scale text-image supervision (e.g., CLIP) have enabled zero-shot transfer to downstream image classification tasks. However, the zero-shot performance of CLIP-like models are often insufficient for real-world adoption. In this paper, we aim to leverage the abundant unlabeled data to improve the performance of a pre-trained zero-shot classifier on downstream tasks. We propose Masked Unsupervised Self-Training (MUST), a new approach which leverages two different and complimentary sources of supervision: pseudo-labels and raw images. MUST jointly optimizes three objectives to learn both class-level global feature and pixel-level local feature and enforces a regularization between the two. We demonstrate the efficacy of MUST on 8 downstream tasks across a variety of domains, where it improves upon CLIP by a large margin and narrows the performance gap between unsupervised and supervised classification. For instance, MUST achieves a zero-shot top-1 accuracy of 77.7% on ImageNet using ViT-B, +9.4% higher than CLIP. Our code is available at //github.com/salesforce/MUST.

Combining information from multi-view images is crucial to improve the performance and robustness of automated methods for disease diagnosis. However, due to the non-alignment characteristics of multi-view images, building correlation and data fusion across views largely remain an open problem. In this study, we present TransFusion, a Transformer-based architecture to merge divergent multi-view imaging information using convolutional layers and powerful attention mechanisms. In particular, the Divergent Fusion Attention (DiFA) module is proposed for rich cross-view context modeling and semantic dependency mining, addressing the critical issue of capturing long-range correlations between unaligned data from different image views. We further propose the Multi-Scale Attention (MSA) to collect global correspondence of multi-scale feature representations. We evaluate TransFusion on the Multi-Disease, Multi-View \& Multi-Center Right Ventricular Segmentation in Cardiac MRI (M\&Ms-2) challenge cohort. TransFusion demonstrates leading performance against the state-of-the-art methods and opens up new perspectives for multi-view imaging integration towards robust medical image segmentation.

In this paper we present Mask DINO, a unified object detection and segmentation framework. Mask DINO extends DINO (DETR with Improved Denoising Anchor Boxes) by adding a mask prediction branch which supports all image segmentation tasks (instance, panoptic, and semantic). It makes use of the query embeddings from DINO to dot-product a high-resolution pixel embedding map to predict a set of binary masks. Some key components in DINO are extended for segmentation through a shared architecture and training process. Mask DINO is simple, efficient, scalable, and benefits from joint large-scale detection and segmentation datasets. Our experiments show that Mask DINO significantly outperforms all existing specialized segmentation methods, both on a ResNet-50 backbone and a pre-trained model with SwinL backbone. Notably, Mask DINO establishes the best results to date on instance segmentation (54.5 AP on COCO), panoptic segmentation (59.4 PQ on COCO), and semantic segmentation (60.8 mIoU on ADE20K). Code will be avaliable at \url{//github.com/IDEACVR/MaskDINO}.

Accurate brain tumor segmentation from Magnetic Resonance Imaging (MRI) is desirable to joint learning of multimodal images. However, in clinical practice, it is not always possible to acquire a complete set of MRIs, and the problem of missing modalities causes severe performance degradation in existing multimodal segmentation methods. In this work, we present the first attempt to exploit the Transformer for multimodal brain tumor segmentation that is robust to any combinatorial subset of available modalities. Concretely, we propose a novel multimodal Medical Transformer (mmFormer) for incomplete multimodal learning with three main components: the hybrid modality-specific encoders that bridge a convolutional encoder and an intra-modal Transformer for both local and global context modeling within each modality; an inter-modal Transformer to build and align the long-range correlations across modalities for modality-invariant features with global semantics corresponding to tumor region; a decoder that performs a progressive up-sampling and fusion with the modality-invariant features to generate robust segmentation. Besides, auxiliary regularizers are introduced in both encoder and decoder to further enhance the model's robustness to incomplete modalities. We conduct extensive experiments on the public BraTS $2018$ dataset for brain tumor segmentation. The results demonstrate that the proposed mmFormer outperforms the state-of-the-art methods for incomplete multimodal brain tumor segmentation on almost all subsets of incomplete modalities, especially by an average 19.07% improvement of Dice on tumor segmentation with only one available modality. The code is available at //github.com/YaoZhang93/mmFormer.

Contrastive learning has shown great promise over annotation scarcity problems in the context of medical image segmentation. Existing approaches typically assume a balanced class distribution for both labeled and unlabeled medical images. However, medical image data in reality is commonly imbalanced (i.e., multi-class label imbalance), which naturally yields blurry contours and usually incorrectly labels rare objects. Moreover, it remains unclear whether all negative samples are equally negative. In this work, we present ACTION, an Anatomical-aware ConTrastive dIstillatiON framework, for semi-supervised medical image segmentation. Specifically, we first develop an iterative contrastive distillation algorithm by softly labeling the negatives rather than binary supervision between positive and negative pairs. We also capture more semantically similar features from the randomly chosen negative set compared to the positives to enforce the diversity of the sampled data. Second, we raise a more important question: Can we really handle imbalanced samples to yield better performance? Hence, the key innovation in ACTION is to learn global semantic relationship across the entire dataset and local anatomical features among the neighbouring pixels with minimal additional memory footprint. During the training, we introduce anatomical contrast by actively sampling a sparse set of hard negative pixels, which can generate smoother segmentation boundaries and more accurate predictions. Extensive experiments across two benchmark datasets and different unlabeled settings show that ACTION performs comparable or better than the current state-of-the-art supervised and semi-supervised methods. Our code and models will be publicly available.

Human perception is routinely assessing the similarity between images, both for decision making and creative thinking. But the underlying cognitive process is not really well understood yet, hence difficult to be mimicked by computer vision systems. State-of-the-art approaches using deep architectures are often based on the comparison of images described as feature vectors learned for image categorization task. As a consequence, such features are powerful to compare semantically related images but not really efficient to compare images visually similar but semantically unrelated. Inspired by previous works on neural features adaptation to psycho-cognitive representations, we focus here on the specific task of learning visual image similarities when analogy matters. We propose to compare different supervised, semi-supervised and self-supervised networks, pre-trained on distinct scales and contents datasets (such as ImageNet-21k, ImageNet-1K or VGGFace2) to conclude which model may be the best to approximate the visual cortex and learn only an adaptation function corresponding to the approximation of the the primate IT cortex through the metric learning framework. Our experiments conducted on the Totally Looks Like image dataset highlight the interest of our method, by increasing the retrieval scores of the best model @1 by 2.25x. This research work was recently accepted for publication at the ICIP 2021 international conference [1]. In this new article, we expand on this previous work by using and comparing new pre-trained feature extractors on other datasets.

We seek to provide an interpretable framework for segmenting users in a population for personalized decision-making. We propose a general methodology, Market Segmentation Trees (MSTs), for learning market segmentations explicitly driven by identifying differences in user response patterns. To demonstrate the versatility of our methodology, we design two new, specialized MST algorithms: (i) Choice Model Trees (CMTs), which can be used to predict a user's choice amongst multiple options and (ii) Isotonic Regression Trees (IRTs), which can be used to solve the bid landscape forecasting problem. We provide a theoretical analysis of the asymptotic running times of our algorithmic methods, which validates their computational tractability on large datasets. We also provide a customizable, open-source code base for training MSTs in Python which employs several strategies for scalability, including parallel processing and warm starts. Finally, we assess the practical performance of MSTs on several synthetic and real world datasets, showing that our method reliably finds market segmentations which accurately model response behavior. Moreover, MSTs are interpretable since the market segments can easily be described by a decision tree and often require only a fraction of the number of market segments generated by traditional approaches.

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8% of benchmark performance using only two labeled MRI volumes for training, corresponding to only 4% (for ACDC) of the training data used to train the benchmark.