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Red-lesions, i.e., microaneurysms (MAs) and hemorrhages (HMs), are the early signs of diabetic retinopathy (DR). The automatic detection of MAs and HMs on retinal fundus images is a challenging task. Most of the existing methods detect either only MAs or only HMs because of the difference in their texture, sizes, and morphology. Though some methods detect both MAs and HMs, they suffer from the curse of dimensionality of shape and colors features and fail to detect all shape variations of HMs such as flame-shaped HM. Leveraging the progress in deep learning, we proposed a two-stream red lesions detection system dealing simultaneously with small and large red lesions. For this system, we introduced a new ROIs candidates generation method for large red lesions fundus images; it is based on blood vessel segmentation and morphological operations, and reduces the computational complexity, and enhances the detection accuracy by generating a small number of potential candidates. For detection, we adapted the Faster RCNN framework with two streams. We used pre-trained VGGNet as a bone model and carried out several extensive experiments to tune it for vessels segmentation and candidates generation, and finally learning the appropriate mapping, which yields better detection of the red lesions comparing with the state-of-the-art methods. The experimental results validated the effectiveness of the system in the detection of both MAs and HMs; the method yields higher performance for per lesion detection according to sensitivity under 4 FPIs on DiaretDB1-MA and DiaretDB1-HM datasets, and 1 FPI on e-ophtha and ROCh datasets than the state of the art methods w.r.t. various evaluation metrics. For DR screening, the system outperforms other methods on DiaretDB1-MA, DiaretDB1-HM, and e-ophtha datasets.

Weakly-Supervised Object Detection (WSOD) and Localization (WSOL), i.e., detecting multiple and single instances with bounding boxes in an image using image-level labels, are long-standing and challenging tasks in the CV community. With the success of deep neural networks in object detection, both WSOD and WSOL have received unprecedented attention. Hundreds of WSOD and WSOL methods and numerous techniques have been proposed in the deep learning era. To this end, in this paper, we consider WSOL is a sub-task of WSOD and provide a comprehensive survey of the recent achievements of WSOD. Specifically, we firstly describe the formulation and setting of the WSOD, including the background, challenges, basic framework. Meanwhile, we summarize and analyze all advanced techniques and training tricks for improving detection performance. Then, we introduce the widely-used datasets and evaluation metrics of WSOD. Lastly, we discuss the future directions of WSOD. We believe that these summaries can help pave a way for future research on WSOD and WSOL.

Domain generalization (DG), i.e., out-of-distribution generalization, has attracted increased interests in recent years. Domain generalization deals with a challenging setting where one or several different but related domain(s) are given, and the goal is to learn a model that can generalize to an unseen test domain. For years, great progress has been achieved. This paper presents the first review for recent advances in domain generalization. First, we provide a formal definition of domain generalization and discuss several related fields. Next, we thoroughly review the theories related to domain generalization and carefully analyze the theory behind generalization. Then, we categorize recent algorithms into three classes and present them in detail: data manipulation, representation learning, and learning strategy, each of which contains several popular algorithms. Third, we introduce the commonly used datasets and applications. Finally, we summarize existing literature and present some potential research topics for the future.

Deep Learning (DL) is vulnerable to out-of-distribution and adversarial examples resulting in incorrect outputs. To make DL more robust, several posthoc anomaly detection techniques to detect (and discard) these anomalous samples have been proposed in the recent past. This survey tries to provide a structured and comprehensive overview of the research on anomaly detection for DL based applications. We provide a taxonomy for existing techniques based on their underlying assumptions and adopted approaches. We discuss various techniques in each of the categories and provide the relative strengths and weaknesses of the approaches. Our goal in this survey is to provide an easier yet better understanding of the techniques belonging to different categories in which research has been done on this topic. Finally, we highlight the unsolved research challenges while applying anomaly detection techniques in DL systems and present some high-impact future research directions.

Compared with model architectures, the training process, which is also crucial to the success of detectors, has received relatively less attention in object detection. In this work, we carefully revisit the standard training practice of detectors, and find that the detection performance is often limited by the imbalance during the training process, which generally consists in three levels - sample level, feature level, and objective level. To mitigate the adverse effects caused thereby, we propose Libra R-CNN, a simple but effective framework towards balanced learning for object detection. It integrates three novel components: IoU-balanced sampling, balanced feature pyramid, and balanced L1 loss, respectively for reducing the imbalance at sample, feature, and objective level. Benefitted from the overall balanced design, Libra R-CNN significantly improves the detection performance. Without bells and whistles, it achieves 2.5 points and 2.0 points higher Average Precision (AP) than FPN Faster R-CNN and RetinaNet respectively on MSCOCO.

Deep learning based models have had great success in object detection, but the state of the art models have not yet been widely applied to biological image data. We apply for the first time an object detection model previously used on natural images to identify cells and recognize their stages in brightfield microscopy images of malaria-infected blood. Many micro-organisms like malaria parasites are still studied by expert manual inspection and hand counting. This type of object detection task is challenging due to factors like variations in cell shape, density, and color, and uncertainty of some cell classes. In addition, annotated data useful for training is scarce, and the class distribution is inherently highly imbalanced due to the dominance of uninfected red blood cells. We use Faster Region-based Convolutional Neural Network (Faster R-CNN), one of the top performing object detection models in recent years, pre-trained on ImageNet but fine tuned with our data, and compare it to a baseline, which is based on a traditional approach consisting of cell segmentation, extraction of several single-cell features, and classification using random forests. To conduct our initial study, we collect and label a dataset of 1300 fields of view consisting of around 100,000 individual cells. We demonstrate that Faster R-CNN outperforms our baseline and put the results in context of human performance.

There is growing interest in object detection in advanced driver assistance systems and autonomous robots and vehicles. To enable such innovative systems, we need faster object detection. In this work, we investigate the trade-off between accuracy and speed with domain-specific approximations, i.e. category-aware image size scaling and proposals scaling, for two state-of-the-art deep learning-based object detection meta-architectures. We study the effectiveness of applying approximation both statically and dynamically to understand the potential and the applicability of them. By conducting experiments on the ImageNet VID dataset, we show that domain-specific approximation has great potential to improve the speed of the system without deteriorating the accuracy of object detectors, i.e. up to 7.5x speedup for dynamic domain-specific approximation. To this end, we present our insights toward harvesting domain-specific approximation as well as devise a proof-of-concept runtime, AutoFocus, that exploits dynamic domain-specific approximation.

Generic object detection, aiming at locating object instances from a large number of predefined categories in natural images, is one of the most fundamental and challenging problems in computer vision. Deep learning techniques have emerged in recent years as powerful methods for learning feature representations directly from data, and have led to remarkable breakthroughs in the field of generic object detection. Given this time of rapid evolution, the goal of this paper is to provide a comprehensive survey of the recent achievements in this field brought by deep learning techniques. More than 250 key contributions are included in this survey, covering many aspects of generic object detection research: leading detection frameworks and fundamental subproblems including object feature representation, object proposal generation, context information modeling and training strategies; evaluation issues, specifically benchmark datasets, evaluation metrics, and state of the art performance. We finish by identifying promising directions for future research.

Deep convolutional neural networks have become a key element in the recent breakthrough of salient object detection. However, existing CNN-based methods are based on either patch-wise (region-wise) training and inference or fully convolutional networks. Methods in the former category are generally time-consuming due to severe storage and computational redundancies among overlapping patches. To overcome this deficiency, methods in the second category attempt to directly map a raw input image to a predicted dense saliency map in a single network forward pass. Though being very efficient, it is arduous for these methods to detect salient objects of different scales or salient regions with weak semantic information. In this paper, we develop hybrid contrast-oriented deep neural networks to overcome the aforementioned limitations. Each of our deep networks is composed of two complementary components, including a fully convolutional stream for dense prediction and a segment-level spatial pooling stream for sparse saliency inference. We further propose an attentional module that learns weight maps for fusing the two saliency predictions from these two streams. A tailored alternate scheme is designed to train these deep networks by fine-tuning pre-trained baseline models. Finally, a customized fully connected CRF model incorporating a salient contour feature embedding can be optionally applied as a post-processing step to improve spatial coherence and contour positioning in the fused result from these two streams. Extensive experiments on six benchmark datasets demonstrate that our proposed model can significantly outperform the state of the art in terms of all popular evaluation metrics.

Object detection typically assumes that training and test data are drawn from an identical distribution, which, however, does not always hold in practice. Such a distribution mismatch will lead to a significant performance drop. In this work, we aim to improve the cross-domain robustness of object detection. We tackle the domain shift on two levels: 1) the image-level shift, such as image style, illumination, etc, and 2) the instance-level shift, such as object appearance, size, etc. We build our approach based on the recent state-of-the-art Faster R-CNN model, and design two domain adaptation components, on image level and instance level, to reduce the domain discrepancy. The two domain adaptation components are based on H-divergence theory, and are implemented by learning a domain classifier in adversarial training manner. The domain classifiers on different levels are further reinforced with a consistency regularization to learn a domain-invariant region proposal network (RPN) in the Faster R-CNN model. We evaluate our newly proposed approach using multiple datasets including Cityscapes, KITTI, SIM10K, etc. The results demonstrate the effectiveness of our proposed approach for robust object detection in various domain shift scenarios.