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Large-scale public datasets with high-quality annotations are rarely available for intelligent medical imaging research, due to data privacy concerns and the cost of annotations. In this paper, we release SynFundus-1M, a high-quality synthetic dataset containing over one million fundus images in terms of \textbf{eleven disease types}. Furthermore, we deliberately assign four readability labels to the key regions of the fundus images. To the best of our knowledge, SynFundus-1M is currently the largest fundus dataset with the most sophisticated annotations. Leveraging over 1.3 million private authentic fundus images from various scenarios, we trained a powerful Denoising Diffusion Probabilistic Model, named SynFundus-Generator. The released SynFundus-1M are generated by SynFundus-Generator under predefined conditions. To demonstrate the value of SynFundus-1M, extensive experiments are designed in terms of the following aspect: 1) Authenticity of the images: we randomly blend the synthetic images with authentic fundus images, and find that experienced annotators can hardly distinguish the synthetic images from authentic ones. Moreover, we show that the disease-related vision features (e.g. lesions) are well simulated in the synthetic images. 2) Effectiveness for down-stream fine-tuning and pretraining: we demonstrate that retinal disease diagnosis models of either convolutional neural networks (CNN) or Vision Transformer (ViT) architectures can benefit from SynFundus-1M, and compared to the datasets commonly used for pretraining, models trained on SynFundus-1M not only achieve superior performance but also demonstrate faster convergence on various downstream tasks. SynFundus-1M is already public available for the open-source community.

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數據集,又稱為資料集、數據集合或資料集合,是一種由數據所組成的集合。
Data set(或dataset)是一個數據的集合,通常以表格形式出現。每一列代表一個特定變量。每一行都對應于某一成員的數據集的問題。它列出的價值觀為每一個變量,如身高和體重的一個物體或價值的隨機數。每個數值被稱為數據資料。對應于行數,該數據集的數據可能包括一個或多個成員。

Radiology report generation (RRG) aims to automatically generate free-text descriptions from clinical radiographs, e.g., chest X-Ray images. RRG plays an essential role in promoting clinical automation and presents significant help to provide practical assistance for inexperienced doctors and alleviate radiologists' workloads. Therefore, consider these meaningful potentials, research on RRG is experiencing explosive growth in the past half-decade, especially with the rapid development of deep learning approaches. Existing studies perform RRG from the perspective of enhancing different modalities, provide insights on optimizing the report generation process with elaborated features from both visual and textual information, and further facilitate RRG with the cross-modal interactions among them. In this paper, we present a comprehensive review of deep learning-based RRG from various perspectives. Specifically, we firstly cover pivotal RRG approaches based on the task-specific features of radiographs, reports, and the cross-modal relations between them, and then illustrate the benchmark datasets conventionally used for this task with evaluation metrics, subsequently analyze the performance of different approaches and finally offer our summary on the challenges and the trends in future directions. Overall, the goal of this paper is to serve as a tool for understanding existing literature and inspiring potential valuable research in the field of RRG.

The recent prevalence of publicly accessible, large medical imaging datasets has led to a proliferation of artificial intelligence (AI) models for cardiovascular image classification and analysis. At the same time, the potentially significant impacts of these models have motivated the development of a range of explainable AI (XAI) methods that aim to explain model predictions given certain image inputs. However, many of these methods are not developed or evaluated with domain experts, and explanations are not contextualized in terms of medical expertise or domain knowledge. In this paper, we propose a novel framework and python library, MiMICRI, that provides domain-centered counterfactual explanations of cardiovascular image classification models. MiMICRI helps users interactively select and replace segments of medical images that correspond to morphological structures. From the counterfactuals generated, users can then assess the influence of each segment on model predictions, and validate the model against known medical facts. We evaluate this library with two medical experts. Our evaluation demonstrates that a domain-centered XAI approach can enhance the interpretability of model explanations, and help experts reason about models in terms of relevant domain knowledge. However, concerns were also surfaced about the clinical plausibility of the counterfactuals generated. We conclude with a discussion on the generalizability and trustworthiness of the MiMICRI framework, as well as the implications of our findings on the development of domain-centered XAI methods for model interpretability in healthcare contexts.

In mesh simplification, common requirements like accuracy, triangle quality, and feature alignment are often considered as a trade-off. Existing algorithms concentrate on just one or a few specific aspects of these requirements. For example, the well-known Quadric Error Metrics (QEM) approach prioritizes accuracy and can preserve strong feature lines/points as well but falls short in ensuring high triangle quality and may degrade weak features that are not as distinctive as strong ones. In this paper, we propose a smooth functional that simultaneously considers all of these requirements. The functional comprises a normal anisotropy term and a Centroidal Voronoi Tessellation (CVT) energy term, with the variables being a set of movable points lying on the surface. The former inherits the spirit of QEM but operates in a continuous setting, while the latter encourages even point distribution, allowing various surface metrics. We further introduce a decaying weight to automatically balance the two terms. We selected 100 CAD models from the ABC dataset, along with 21 organic models, to compare the existing mesh simplification algorithms with ours. Experimental results reveal an important observation: the introduction of a decaying weight effectively reduces the conflict between the two terms and enables the alignment of weak features. This distinctive feature sets our approach apart from most existing mesh simplification methods and demonstrates significant potential in shape understanding.

Recently, implicit neural representations (INR) have made significant strides in various vision-related domains, providing a novel solution for Multispectral and Hyperspectral Image Fusion (MHIF) tasks. However, INR is prone to losing high-frequency information and is confined to the lack of global perceptual capabilities. To address these issues, this paper introduces a Fourier-enhanced Implicit Neural Fusion Network (FeINFN) specifically designed for MHIF task, targeting the following phenomena: The Fourier amplitudes of the HR-HSI latent code and LR-HSI are remarkably similar; however, their phases exhibit different patterns. In FeINFN, we innovatively propose a spatial and frequency implicit fusion function (Spa-Fre IFF), helping INR capture high-frequency information and expanding the receptive field. Besides, a new decoder employing a complex Gabor wavelet activation function, called Spatial-Frequency Interactive Decoder (SFID), is invented to enhance the interaction of INR features. Especially, we further theoretically prove that the Gabor wavelet activation possesses a time-frequency tightness property that favors learning the optimal bandwidths in the decoder. Experiments on two benchmark MHIF datasets verify the state-of-the-art (SOTA) performance of the proposed method, both visually and quantitatively. Also, ablation studies demonstrate the mentioned contributions. The code will be available on Anonymous GitHub (//anonymous.4open.science/r/FeINFN-15C9/) after possible acceptance.

With the advanced ability to capture longitudinal sensed data and model human behavior, behavioral sensing technologies are progressing toward numerous wellbeing applications. However, the widespread use of top-down design approaches, often based on assumptions made by technology builders about user goals, needs, and preferences, can result in a lack of context sensitivity. Such oversights may lead to technologies that do not fully support the diverse needs of users and may even introduce potential harms. In this paper, we highlight two primary areas of potential harm in behavioral sensing technologies: identity-based and situation-based harms. By adopting a theory-driven approach, we propose a framework for identifying and mitigating these harms. To validate this framework, we applied it to two real-world studies of behavioral sensing as tools for systematic evaluation. Our analysis provides empirical evidence of potential harms and demonstrates the framework's effectiveness in identifying and addressing these issues. The insights derived from our evaluations, coupled with the reflection on the framework, contribute both conceptually and practically to the field. Our goal is to guide technology builders in designing more context-sensitive sensing technologies, thereby supporting responsible decision-making in this rapidly evolving field.

Data-driven applications and services have been increasingly deployed in all aspects of life including healthcare and medical services in which a huge amount of personal data is collected, aggregated, and processed in a centralised server from various sources. As a consequence, preserving the data privacy and security of these applications is of paramount importance. Since May 2018, the new data protection legislation in the EU/UK, namely the General Data Protection Regulation (GDPR), has come into force and this has called for a critical need for modelling compliance with the GDPR's sophisticated requirements. Existing threat modelling techniques are not designed to model GDPR compliance, particularly in a complex system where personal data is collected, processed, manipulated, and shared with third parties. In this paper, we present a novel comprehensive solution for developing a threat modelling technique to address threats of non-compliance and mitigate them by taking GDPR requirements as the baseline and combining them with the existing security and privacy modelling techniques (i.e., \textit{STRIDE} and \textit{LINDDUN}, respectively). For this purpose, we propose a new data flow diagram integrated with the GDPR principles, develop a knowledge base for the non-compliance threats, and leverage an inference engine for reasoning the GDPR non-compliance threats over the knowledge base. Finally, we demonstrate our solution for threats of non-compliance with legal basis and accountability in a telehealth system to show the feasibility and effectiveness of the proposed solution.

In recent years, the neural network backdoor hidden in the parameters of the federated learning model has been proved to have great security risks. Considering the characteristics of trigger generation, data poisoning and model training in backdoor attack, this paper designs a backdoor attack method based on federated learning. Firstly, aiming at the concealment of the backdoor trigger, a TrojanGan steganography model with encoder-decoder structure is designed. The model can encode specific attack information as invisible noise and attach it to the image as a backdoor trigger, which improves the concealment and data transformations of the backdoor trigger.Secondly, aiming at the problem of single backdoor trigger mode, an image poisoning attack method called combination trigger attack is proposed. This method realizes multi-backdoor triggering by multiplexing combined triggers and improves the robustness of backdoor attacks. Finally, aiming at the problem that the local training mechanism leads to the decrease of the success rate of backdoor attack, a dual model replacement backdoor attack algorithm based on federated learning is designed. This method can improve the success rate of backdoor attack while maintaining the performance of the federated learning aggregation model. Experiments show that the attack strategy in this paper can not only achieve high backdoor concealment and diversification of trigger forms under federated learning, but also achieve good attack success rate in multi-target attacks.door concealment and diversification of trigger forms but also achieve good results in multi-target attacks.

Unsupervised Representation Learning on graphs is gaining traction due to the increasing abundance of unlabelled network data and the compactness, richness, and usefulness of the representations generated. In this context, the need to consider fairness and bias constraints while generating the representations has been well-motivated and studied to some extent in prior works. One major limitation of most of the prior works in this setting is that they do not aim to address the bias generated due to connectivity patterns in the graphs, such as varied node centrality, which leads to a disproportionate performance across nodes. In our work, we aim to address this issue of mitigating bias due to inherent graph structure in an unsupervised setting. To this end, we propose CAFIN, a centrality-aware fairness-inducing framework that leverages the structural information of graphs to tune the representations generated by existing frameworks. We deploy it on GraphSAGE (a popular framework in this domain) and showcase its efficacy on two downstream tasks - Node Classification and Link Prediction. Empirically, CAFIN consistently reduces the performance disparity across popular datasets (varying from 18 to 80% reduction in performance disparity) from various domains while incurring only a minimal cost of fairness.

Largely due to their implicit nature, neural fields lack a direct mechanism for filtering, as Fourier analysis from discrete signal processing is not directly applicable to these representations. Effective filtering of neural fields is critical to enable level-of-detail processing in downstream applications, and support operations that involve sampling the field on regular grids (e.g. marching cubes). Existing methods that attempt to decompose neural fields in the frequency domain either resort to heuristics or require extensive modifications to the neural field architecture. We show that via a simple modification, one can obtain neural fields that are low-pass filtered, and in turn show how this can be exploited to obtain a frequency decomposition of the entire signal. We demonstrate the validity of our technique by investigating level-of-detail reconstruction, and showing how coarser representations can be computed effectively.

Recently, graph neural networks have been gaining a lot of attention to simulate dynamical systems due to their inductive nature leading to zero-shot generalizability. Similarly, physics-informed inductive biases in deep-learning frameworks have been shown to give superior performance in learning the dynamics of physical systems. There is a growing volume of literature that attempts to combine these two approaches. Here, we evaluate the performance of thirteen different graph neural networks, namely, Hamiltonian and Lagrangian graph neural networks, graph neural ODE, and their variants with explicit constraints and different architectures. We briefly explain the theoretical formulation highlighting the similarities and differences in the inductive biases and graph architecture of these systems. We evaluate these models on spring, pendulum, gravitational, and 3D deformable solid systems to compare the performance in terms of rollout error, conserved quantities such as energy and momentum, and generalizability to unseen system sizes. Our study demonstrates that GNNs with additional inductive biases, such as explicit constraints and decoupling of kinetic and potential energies, exhibit significantly enhanced performance. Further, all the physics-informed GNNs exhibit zero-shot generalizability to system sizes an order of magnitude larger than the training system, thus providing a promising route to simulate large-scale realistic systems.

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