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Accurate and early prediction of a disease allows to plan and improve a patient's quality of future life. During pandemic situations, the medical decision becomes a speed challenge in which physicians have to act fast to diagnose and predict the risk of the severity of the disease, moreover this is also of high priority for neurodegenerative diseases like Parkinson's disease. Machine Learning (ML) models with Features Selection (FS) techniques can be applied to help physicians to quickly diagnose a disease. FS optimally subset features that improve a model performance and help reduce the number of needed tests for a patient and hence speeding up the diagnosis. This study shows the result of three Feature Selection (FS) techniques pre-applied to a classifier algorithm, Logistic Regression, on non-invasive test results data. The three FS are Analysis of Variance (ANOVA) as filter based method, Least Absolute Shrinkage and Selection Operator (LASSO) as embedded method and Sequential Feature Selection (SFS) as wrapper method. The outcome shows that FS technique can help to build an efficient and effective classifier, hence improving the performance of the classifier while reducing the computation time.

With increasing memory demands for datacenter applications and the emergence of coherent interfaces like CXL that enable main memory expansion, we are about to observe a wide adoption of tiered-memory subsystems in hyperscalers. In such systems, main memory can constitute different memory technologies with varied performance characteristics. In this paper, we characterize the memory usage of a wide range of datacenter applications across the server fleet of a hyperscaler (Meta) to get insights into an application's memory access patterns and performance on a tiered memory system. Our characterizations show that datacenter applications can benefit from tiered memory systems as there exist opportunities for offloading colder pages to slower memory tiers. Without efficient memory management, however, such systems can significantly degrade performance. We propose a novel OS-level application-transparent page placement mechanism (TPP) for efficient memory management. TPP employs a lightweight mechanism to identify and place hot and cold pages to appropriate memory tiers. It enables page allocation to work independently from page reclamation logic that is, otherwise, tightly coupled in today's Linux kernel. As a result, the local memory tier has memory headroom for new allocations. At the same time, TPP can promptly promote performance-critical hot pages trapped in the slow memory tiers to the fast tier node. Both promotion and demotion mechanisms work transparently without any prior knowledge of an application's memory access behavior. We evaluate TPP with diverse workloads that consume significant portions of DRAM on Meta's server fleet and are sensitive to memory subsystem performance. TPP's efficient page placement improves Linux's performance by up to 18%. TPP outperforms NUMA balancing and AutoTiering, state-of-the-art solutions for tiered memory, by 10-17%.

Despite the recent success of machine learning algorithms, most of these models still face several drawbacks when considering more complex tasks requiring interaction between different sources, such as multimodal input data and logical time sequence. On the other hand, the biological brain is highly sharpened in this sense, empowered to automatically manage and integrate such a stream of information through millions of years of evolution. In this context, this paper finds inspiration from recent discoveries on cortical circuits in the brain to propose a more biologically plausible self-supervised machine learning approach that combines multimodal information using intra-layer modulations together with canonical correlation analysis (CCA), as well as a memory mechanism to keep track of temporal data, the so-called Canonical Cortical Graph Neural networks. The approach outperformed recent state-of-the-art results considering both better clean audio reconstruction and energy efficiency, described by a reduced and smother neuron firing rate distribution, suggesting the model as a suitable approach for speech enhancement in future audio-visual hearing aid devices.

Power and information asymmetries between people and digital technology companies have predominantly been legitimized through contractual agreements that have failed to provide diverse people with meaningful consent and contestability. We offer an interdisciplinary multidimensional perspective on the future of regulatory frameworks - the Terms-we-Serve-with (TwSw) social, computational, and legal contract for restructuring power asymmetries and center-periphery dynamics to enable improved human agency in individual and collective experiences of algorithmic harms.

When neural network model and data are outsourced to cloud server for inference, it is desired to preserve the confidentiality of model and data as the involved parties (i.e., cloud server, model providing client and data providing client) may not trust mutually. Solutions were proposed based on multi-party computation, trusted execution environment (TEE) and leveled or fully homomorphic encryption (LHE/FHE), but their limitations hamper practical application. We propose a new framework based on synergistic integration of LHE and TEE, which enables collaboration among mutually-untrusted three parties, while minimizing the involvement of (relatively) resource-constrained TEE and allowing the full utilization of the untrusted but more resource-rich part of server. We also propose a generic and efficient LHE-based inference scheme as an important performance-determining component of the framework. We implemented/evaluated the proposed system on a moderate platform and show that, our proposed scheme is more applicable/scalable to various settings, and has better performance, compared to the state-of-the-art LHE-based solutions.

Mesh degeneration is a bottleneck for fluid-structure interaction (FSI) simulations and for shape optimization via the method of mappings. In both cases, an appropriate mesh motion technique is required. The choice is typically based on heuristics, e.g., the solution operators of partial differential equations (PDE), such as the Laplace or biharmonic equation. Especially the latter, which shows good numerical performance for large displacements, is expensive. Moreover, from a continuous perspective, choosing the mesh motion technique is to a certain extent arbitrary and has no influence on the physically relevant quantities. Therefore, we consider approaches inspired by machine learning. We present a hybrid PDE-NN approach, where the neural network (NN) serves as parameterization of a coefficient in a second order nonlinear PDE. We ensure existence of solutions for the nonlinear PDE by the choice of the neural network architecture. Moreover, we propose a splitting of the monolithic FSI system into three smaller subsystems, in order to segregate the mesh motion. We assess the quality of the learned mesh motion technique by applying it to a FSI benchmark problem.

The quintessential model-based reinforcement-learning agent iteratively refines its estimates or prior beliefs about the true underlying model of the environment. Recent empirical successes in model-based reinforcement learning with function approximation, however, eschew the true model in favor of a surrogate that, while ignoring various facets of the environment, still facilitates effective planning over behaviors. Recently formalized as the value equivalence principle, this algorithmic technique is perhaps unavoidable as real-world reinforcement learning demands consideration of a simple, computationally-bounded agent interacting with an overwhelmingly complex environment, whose underlying dynamics likely exceed the agent's capacity for representation. In this work, we consider the scenario where agent limitations may entirely preclude identifying an exactly value-equivalent model, immediately giving rise to a trade-off between identifying a model that is simple enough to learn while only incurring bounded sub-optimality. To address this problem, we introduce an algorithm that, using rate-distortion theory, iteratively computes an approximately-value-equivalent, lossy compression of the environment which an agent may feasibly target in lieu of the true model. We prove an information-theoretic, Bayesian regret bound for our algorithm that holds for any finite-horizon, episodic sequential decision-making problem. Crucially, our regret bound can be expressed in one of two possible forms, providing a performance guarantee for finding either the simplest model that achieves a desired sub-optimality gap or, alternatively, the best model given a limit on agent capacity.

Several deep neural networks have recently been shown to generate activations similar to those of the brain in response to the same input. These algorithms, however, remain largely implausible: they require (1) extraordinarily large amounts of data, (2) unobtainable supervised labels, (3) textual rather than raw sensory input, and / or (4) implausibly large memory (e.g. thousands of contextual words). These elements highlight the need to identify algorithms that, under these limitations, would suffice to account for both behavioral and brain responses. Focusing on the issue of speech processing, we here hypothesize that self-supervised algorithms trained on the raw waveform constitute a promising candidate. Specifically, we compare a recent self-supervised architecture, Wav2Vec 2.0, to the brain activity of 412 English, French, and Mandarin individuals recorded with functional Magnetic Resonance Imaging (fMRI), while they listened to ~1h of audio books. Our results are four-fold. First, we show that this algorithm learns brain-like representations with as little as 600 hours of unlabelled speech -- a quantity comparable to what infants can be exposed to during language acquisition. Second, its functional hierarchy aligns with the cortical hierarchy of speech processing. Third, different training regimes reveal a functional specialization akin to the cortex: Wav2Vec 2.0 learns sound-generic, speech-specific and language-specific representations similar to those of the prefrontal and temporal cortices. Fourth, we confirm the similarity of this specialization with the behavior of 386 additional participants. These elements, resulting from the largest neuroimaging benchmark to date, show how self-supervised learning can account for a rich organization of speech processing in the brain, and thus delineate a path to identify the laws of language acquisition which shape the human brain.

It has been a long time that computer architecture and systems are optimized to enable efficient execution of machine learning (ML) algorithms or models. Now, it is time to reconsider the relationship between ML and systems, and let ML transform the way that computer architecture and systems are designed. This embraces a twofold meaning: the improvement of designers' productivity, and the completion of the virtuous cycle. In this paper, we present a comprehensive review of work that applies ML for system design, which can be grouped into two major categories, ML-based modelling that involves predictions of performance metrics or some other criteria of interest, and ML-based design methodology that directly leverages ML as the design tool. For ML-based modelling, we discuss existing studies based on their target level of system, ranging from the circuit level to the architecture/system level. For ML-based design methodology, we follow a bottom-up path to review current work, with a scope of (micro-)architecture design (memory, branch prediction, NoC), coordination between architecture/system and workload (resource allocation and management, data center management, and security), compiler, and design automation. We further provide a future vision of opportunities and potential directions, and envision that applying ML for computer architecture and systems would thrive in the community.

Reinforcement learning is one of the core components in designing an artificial intelligent system emphasizing real-time response. Reinforcement learning influences the system to take actions within an arbitrary environment either having previous knowledge about the environment model or not. In this paper, we present a comprehensive study on Reinforcement Learning focusing on various dimensions including challenges, the recent development of different state-of-the-art techniques, and future directions. The fundamental objective of this paper is to provide a framework for the presentation of available methods of reinforcement learning that is informative enough and simple to follow for the new researchers and academics in this domain considering the latest concerns. First, we illustrated the core techniques of reinforcement learning in an easily understandable and comparable way. Finally, we analyzed and depicted the recent developments in reinforcement learning approaches. My analysis pointed out that most of the models focused on tuning policy values rather than tuning other things in a particular state of reasoning.