Detection of Volatile Organic Compounds (VOCs) from the breath is becoming a viable route for the early detection of diseases non-invasively. This paper presents a sensor array with three metal oxide electrodes that can use machine learning methods to identify four distinct VOCs in a mixture. The metal oxide sensor array was subjected to various VOC concentrations, including ethanol, acetone, toluene and chloroform. The dataset obtained from individual gases and their mixtures were analyzed using multiple machine learning algorithms, such as Random Forest (RF), K-Nearest Neighbor (KNN), Decision Tree, Linear Regression, Logistic Regression, Naive Bayes, Linear Discriminant Analysis, Artificial Neural Network, and Support Vector Machine. KNN and RF have shown more than 99% accuracy in classifying different varying chemicals in the gas mixtures. In regression analysis, KNN has delivered the best results with R2 value of more than 0.99 and LOD of 0.012, 0.015, 0.014 and 0.025 PPM for predicting the concentrations of varying chemicals Acetone, Toluene, Ethanol, and Chloroform, respectively in complex mixtures. Therefore, it is demonstrated that the array utilizing the provided algorithms can classify and predict the concentrations of the four gases simultaneously for disease diagnosis and treatment monitoring.
Mitigation of gender bias in NLP has a long history tied to debiasing static word embeddings. More recently, attention has shifted to debiasing pre-trained language models. We study to what extent the simplest projective debiasing methods, developed for word embeddings, can help when applied to BERT's internal representations. Projective methods are fast to implement, use a small number of saved parameters, and make no updates to the existing model parameters. We evaluate the efficacy of the methods in reducing both intrinsic bias, as measured by BERT's next sentence prediction task, and in mitigating observed bias in a downstream setting when fine-tuned. To this end, we also provide a critical analysis of a popular gender-bias assessment test for quantifying intrinsic bias, resulting in an enhanced test set and new bias measures. We find that projective methods can be effective at both intrinsic bias and downstream bias mitigation, but that the two outcomes are not necessarily correlated. This finding serves as a warning that intrinsic bias test sets, based either on language modeling tasks or next sentence prediction, should not be the only benchmark in developing a debiased language model.
Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial cancer is important for effective patient management and determining the best treatment modalities. This study introduces EndoNet, which uses convolutional neural networks for extracting histologic features and a vision transformer for aggregating these features and classifying slides based on their visual characteristics into high- and low- grade. The model was trained on 929 digitized hematoxylin and eosin-stained whole-slide images of endometrial cancer from hysterectomy cases at Dartmouth-Health. It classifies these slides into low-grade (Endometroid Grades 1 and 2) and high-grade (endometroid carcinoma FIGO grade 3, uterine serous carcinoma, carcinosarcoma) categories. EndoNet was evaluated on an internal test set of 110 patients and an external test set of 100 patients from the public TCGA database. The model achieved a weighted average F1-score of 0.91 (95% CI: 0.86-0.95) and an AUC of 0.95 (95% CI: 0.89-0.99) on the internal test, and 0.86 (95% CI: 0.80-0.94) for F1-score and 0.86 (95% CI: 0.75-0.93) for AUC on the external test. Pending further validation, EndoNet has the potential to support pathologists without the need of manual annotations in classifying the grades of gynecologic pathology tumors.
Detecting Type 2 Diabetes (T2D) and Prediabetes (PD) is a real challenge for medicine due to the absence of pathogenic symptoms and the lack of known associated risk factors. Even though some proposals for machine learning models enable the identification of people at risk, the nature of the condition makes it so that a model suitable for one population may not necessarily be suitable for another. In this article, the development and assessment of predictive models to identify people at risk for T2D and PD specifically in Argentina are discussed. First, the database was thoroughly preprocessed and three specific datasets were generated considering a compromise between the number of records and the amount of available variables. After applying 5 different classification models, the results obtained show that a very good performance was observed for two datasets with some of these models. In particular, RF, DT, and ANN demonstrated great classification power, with good values for the metrics under consideration. Given the lack of this type of tool in Argentina, this work represents the first step towards the development of more sophisticated models.
Reinforcement Learning-based Recommender Systems (RLRS) have shown promise across a spectrum of applications, from e-commerce platforms to streaming services. Yet, they grapple with challenges, notably in crafting reward functions and harnessing large pre-existing datasets within the RL framework. Recent advancements in offline RLRS provide a solution for how to address these two challenges. However, existing methods mainly rely on the transformer architecture, which, as sequence lengths increase, can introduce challenges associated with computational resources and training costs. Additionally, the prevalent methods employ fixed-length input trajectories, restricting their capacity to capture evolving user preferences. In this study, we introduce a new offline RLRS method to deal with the above problems. We reinterpret the RLRS challenge by modeling sequential decision-making as an inference task, leveraging adaptive masking configurations. This adaptive approach selectively masks input tokens, transforming the recommendation task into an inference challenge based on varying token subsets, thereby enhancing the agent's ability to infer across diverse trajectory lengths. Furthermore, we incorporate a multi-scale segmented retention mechanism that facilitates efficient modeling of long sequences, significantly enhancing computational efficiency. Our experimental analysis, conducted on both online simulator and offline datasets, clearly demonstrates the advantages of our proposed method.
Haptic feedback is essential for humans to successfully perform complex and delicate manipulation tasks. A recent rise in tactile sensors has enabled robots to leverage the sense of touch and expand their capability drastically. However, many tasks still need human intervention/guidance. For this reason, we present a teleoperation framework designed to provide haptic feedback to human operators based on the data from camera-based tactile sensors mounted on the robot gripper. Partial autonomy is introduced to prevent slippage of grasped objects during task execution. Notably, we rely exclusively on low-cost off-the-shelf hardware to realize an affordable solution. We demonstrate the versatility of the framework on nine different objects ranging from rigid to soft and fragile ones, using three different operators on real hardware.
The advancement of knowledge distillation has played a crucial role in enabling the transfer of knowledge from larger teacher models to smaller and more efficient student models, and is particularly beneficial for online and resource-constrained applications. The effectiveness of the student model heavily relies on the quality of the distilled knowledge received from the teacher. Given the accessibility of unlabelled remote sensing data, semi-supervised learning has become a prevalent strategy for enhancing model performance. However, relying solely on semi-supervised learning with smaller models may be insufficient due to their limited capacity for feature extraction. This limitation restricts their ability to exploit training data. To address this issue, we propose an integrated approach that combines knowledge distillation and semi-supervised learning methods. This hybrid approach leverages the robust capabilities of large models to effectively utilise large unlabelled data whilst subsequently providing the small student model with rich and informative features for enhancement. The proposed semi-supervised learning-based knowledge distillation (SSLKD) approach demonstrates a notable improvement in the performance of the student model, in the application of road segmentation, surpassing the effectiveness of traditional semi-supervised learning methods.
Instruction-tuned Large Language Models (LLMs) have exhibited impressive language understanding and the capacity to generate responses that follow specific prompts. However, due to the computational demands associated with training these models, their applications often adopt a zero-shot setting. In this paper, we evaluate the zero-shot performance of two publicly accessible LLMs, ChatGPT and OpenAssistant, in the context of six Computational Social Science classification tasks, while also investigating the effects of various prompting strategies. Our experiments investigate the impact of prompt complexity, including the effect of incorporating label definitions into the prompt; use of synonyms for label names; and the influence of integrating past memories during foundation model training. The findings indicate that in a zero-shot setting, current LLMs are unable to match the performance of smaller, fine-tuned baseline transformer models (such as BERT-large). Additionally, we find that different prompting strategies can significantly affect classification accuracy, with variations in accuracy and F1 scores exceeding 10\%.
We propose a Dynamical System (DS) approach to learn complex, possibly periodic motion plans from kinesthetic demonstrations using Neural Ordinary Differential Equations (NODE). To ensure reactivity and robustness to disturbances, we propose a novel approach that selects a target point at each time step for the robot to follow, by combining tools from control theory and the target trajectory generated by the learned NODE. A correction term to the NODE model is computed online by solving a quadratic program that guarantees stability and safety using control Lyapunov functions and control barrier functions, respectively. Our approach outperforms baseline DS learning techniques on the LASA handwriting dataset and complex periodic trajectories. It is also validated on the Franka Emika robot arm to produce stable motions for wiping and stirring tasks that do not have a single attractor, while being robust to perturbations and safe around humans and obstacles.
Graph Neural Networks (GNNs) have recently become increasingly popular due to their ability to learn complex systems of relations or interactions arising in a broad spectrum of problems ranging from biology and particle physics to social networks and recommendation systems. Despite the plethora of different models for deep learning on graphs, few approaches have been proposed thus far for dealing with graphs that present some sort of dynamic nature (e.g. evolving features or connectivity over time). In this paper, we present Temporal Graph Networks (TGNs), a generic, efficient framework for deep learning on dynamic graphs represented as sequences of timed events. Thanks to a novel combination of memory modules and graph-based operators, TGNs are able to significantly outperform previous approaches being at the same time more computationally efficient. We furthermore show that several previous models for learning on dynamic graphs can be cast as specific instances of our framework. We perform a detailed ablation study of different components of our framework and devise the best configuration that achieves state-of-the-art performance on several transductive and inductive prediction tasks for dynamic graphs.
Clinical Named Entity Recognition (CNER) aims to identify and classify clinical terms such as diseases, symptoms, treatments, exams, and body parts in electronic health records, which is a fundamental and crucial task for clinical and translational research. In recent years, deep neural networks have achieved significant success in named entity recognition and many other Natural Language Processing (NLP) tasks. Most of these algorithms are trained end to end, and can automatically learn features from large scale labeled datasets. However, these data-driven methods typically lack the capability of processing rare or unseen entities. Previous statistical methods and feature engineering practice have demonstrated that human knowledge can provide valuable information for handling rare and unseen cases. In this paper, we address the problem by incorporating dictionaries into deep neural networks for the Chinese CNER task. Two different architectures that extend the Bi-directional Long Short-Term Memory (Bi-LSTM) neural network and five different feature representation schemes are proposed to handle the task. Computational results on the CCKS-2017 Task 2 benchmark dataset show that the proposed method achieves the highly competitive performance compared with the state-of-the-art deep learning methods.