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Recent studies revealed that convolutional neural networks do not generalize well to small image transformations, e.g. rotations by a few degrees or translations of a few pixels. To improve the robustness to such transformations, we propose to introduce data augmentation at intermediate layers of the neural architecture, in addition to the common data augmentation applied on the input images. By introducing small perturbations to activation maps (features) at various levels, we develop the capacity of the neural network to cope with such transformations. We conduct experiments on three image classification benchmarks (Tiny ImageNet, Caltech-256 and Food-101), considering two different convolutional architectures (ResNet-18 and DenseNet-121). When compared with two state-of-the-art methods, the empirical results show that our approach consistently attains the best trade-off between accuracy and mean flip rate.

Technology has evolved over the years, making our lives easier. It has impacted the healthcare sector, increasing the average life expectancy of human beings. Still, there are gaps that remain unaddressed. There is a lack of transparency in the healthcare system, which results in inherent trust problems between patients and hospitals. In the present day, a patient does not know whether he or she will get the proper treatment from the hospital for the fee charged. A patient can claim reimbursement of the medical bill from any insurance company. However, today there is minimal scope for the Insurance Company to verify the validity of such bills or medical records. A patient can provide fake details to get financial benefits from the insurance company. Again, there are trust issues between the patient (i.e., the insurance claimer) and the insurance company. Blockchain integrated with the smart contract is a well-known disruptive technology that builds trust by providing transparency to the system. In this paper, we propose a blockchain-enabled Secure and Smart HealthCare System. Fairness of all the entities: patient, hospital, or insurance company involved in the system is guaranteed with no one trusting each other. Privacy and security of patients' medical data are ensured as well. We also propose a method for privacy-preserving sharing of aggregated data with the research community for their own purpose. Shared data must not be personally identifiable, i.e, no one can link the acquired data to the identity of any patient or their medical history. We have implemented the prototype in the Ethereum platform and Ropsten test network, and have included the analysis as well.

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this characteristic also raises security and privacy concerns. In order to balance the risks and benefits, governance mechanisms including regulatory and ethical controls have been established, which are prone to human errors and create hindrance for collaboration. Over the past decade, technological methods are also catching up that can support critical discoveries responsibly. In this paper, we explore regulations and ethical guidelines and propose our visions of secure/private genomic data storage/processing/sharing platforms. Then, we present some available techniques and a conceptual system model that can support our visions. Finally, we highlight the open issues that need further investigation.

Existing Collaborative Filtering (CF) methods are mostly designed based on the idea of matching, i.e., by learning user and item embeddings from data using shallow or deep models, they try to capture the associative relevance patterns in data, so that a user embedding can be matched with relevant item embeddings using designed or learned similarity functions. However, as a cognition rather than a perception intelligent task, recommendation requires not only the ability of pattern recognition and matching from data, but also the ability of cognitive reasoning in data. In this paper, we propose to advance Collaborative Filtering (CF) to Collaborative Reasoning (CR), which means that each user knows part of the reasoning space, and they collaborate for reasoning in the space to estimate preferences for each other. Technically, we propose a Neural Collaborative Reasoning (NCR) framework to bridge learning and reasoning. Specifically, we integrate the power of representation learning and logical reasoning, where representations capture similarity patterns in data from perceptual perspectives, and logic facilitates cognitive reasoning for informed decision making. An important challenge, however, is to bridge differentiable neural networks and symbolic reasoning in a shared architecture for optimization and inference. To solve the problem, we propose a modularized reasoning architecture, which learns logical operations such as AND ($\wedge$), OR ($\vee$) and NOT ($\neg$) as neural modules for implication reasoning ($\rightarrow$). In this way, logical expressions can be equivalently organized as neural networks, so that logical reasoning and prediction can be conducted in a continuous space. Experiments on real-world datasets verified the advantages of our framework compared with both shallow, deep and reasoning models.

Understanding the inner workings of deep neural networks (DNNs) is essential to provide trustworthy artificial intelligence techniques for practical applications. Existing studies typically involve linking semantic concepts to units or layers of DNNs, but fail to explain the inference process. In this paper, we introduce neural architecture disentanglement (NAD) to fill the gap. Specifically, NAD learns to disentangle a pre-trained DNN into sub-architectures according to independent tasks, forming information flows that describe the inference processes. We investigate whether, where, and how the disentanglement occurs through experiments conducted with handcrafted and automatically-searched network architectures, on both object-based and scene-based datasets. Based on the experimental results, we present three new findings that provide fresh insights into the inner logic of DNNs. First, DNNs can be divided into sub-architectures for independent tasks. Second, deeper layers do not always correspond to higher semantics. Third, the connection type in a DNN affects how the information flows across layers, leading to different disentanglement behaviors. With NAD, we further explain why DNNs sometimes give wrong predictions. Experimental results show that misclassified images have a high probability of being assigned to task sub-architectures similar to the correct ones. Code will be available at: //github.com/hujiecpp/NAD.

Potential Drug-Drug Interaction(DDI) occurring while treating complex or co-existing diseases with drug combinations may cause changes in drugs' pharmacological activity. Therefore, DDI prediction has been an important task in the medical healthy machine learning community. Graph-based learning methods have recently aroused widespread interest and are proved to be a priority for this task. However, these methods are often limited to exploiting the inter-view drug molecular structure and ignoring the drug's intra-view interaction relationship, vital to capturing the complex DDI patterns. This study presents a new method, multi-view graph contrastive representation learning for drug-drug interaction prediction, MIRACLE for brevity, to capture inter-view molecule structure and intra-view interactions between molecules simultaneously. MIRACLE treats a DDI network as a multi-view graph where each node in the interaction graph itself is a drug molecular graph instance. We use GCN to encode DDI relationships and a bond-aware attentive message propagating method to capture drug molecular structure information in the MIRACLE learning stage. Also, we propose a novel unsupervised contrastive learning component to balance and integrate the multi-view information. Comprehensive experiments on multiple real datasets show that MIRACLE outperforms the state-of-the-art DDI prediction models consistently.

Graph neural networks (GNNs) are a popular class of machine learning models whose major advantage is their ability to incorporate a sparse and discrete dependency structure between data points. Unfortunately, GNNs can only be used when such a graph-structure is available. In practice, however, real-world graphs are often noisy and incomplete or might not be available at all. With this work, we propose to jointly learn the graph structure and the parameters of graph convolutional networks (GCNs) by approximately solving a bilevel program that learns a discrete probability distribution on the edges of the graph. This allows one to apply GCNs not only in scenarios where the given graph is incomplete or corrupted but also in those where a graph is not available. We conduct a series of experiments that analyze the behavior of the proposed method and demonstrate that it outperforms related methods by a significant margin.

Being able to predict the crowd flows in each and every part of a city, especially in irregular regions, is strategically important for traffic control, risk assessment, and public safety. However, it is very challenging because of interactions and spatial correlations between different regions. In addition, it is affected by many factors: i) multiple temporal correlations among different time intervals: closeness, period, trend; ii) complex external influential factors: weather, events; iii) meta features: time of the day, day of the week, and so on. In this paper, we formulate crowd flow forecasting in irregular regions as a spatio-temporal graph (STG) prediction problem in which each node represents a region with time-varying flows. By extending graph convolution to handle the spatial information, we propose using spatial graph convolution to build a multi-view graph convolutional network (MVGCN) for the crowd flow forecasting problem, where different views can capture different factors as mentioned above. We evaluate MVGCN using four real-world datasets (taxicabs and bikes) and extensive experimental results show that our approach outperforms the adaptations of state-of-the-art methods. And we have developed a crowd flow forecasting system for irregular regions that can now be used internally.

Predictive models of student success in Massive Open Online Courses (MOOCs) are a critical component of effective content personalization and adaptive interventions. In this article we review the state of the art in predictive models of student success in MOOCs and present a categorization of MOOC research according to the predictors (features), prediction (outcomes), and underlying theoretical model. We critically survey work across each category, providing data on the raw data source, feature engineering, statistical model, evaluation method, prediction architecture, and other aspects of these experiments. Such a review is particularly useful given the rapid expansion of predictive modeling research in MOOCs since the emergence of major MOOC platforms in 2012. This survey reveals several key methodological gaps, which include extensive filtering of experimental subpopulations, ineffective student model evaluation, and the use of experimental data which would be unavailable for real-world student success prediction and intervention, which is the ultimate goal of such models. Finally, we highlight opportunities for future research, which include temporal modeling, research bridging predictive and explanatory student models, work which contributes to learning theory, and evaluating long-term learner success in MOOCs.

We introduce a guide to help deep learning practitioners understand and manipulate convolutional neural network architectures. The guide clarifies the relationship between various properties (input shape, kernel shape, zero padding, strides and output shape) of convolutional, pooling and transposed convolutional layers, as well as the relationship between convolutional and transposed convolutional layers. Relationships are derived for various cases, and are illustrated in order to make them intuitive.