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Multiomics data fusion integrates diverse data modalities, ranging from transcriptomics to proteomics, to gain a comprehensive understanding of biological systems and enhance predictions on outcomes of interest related to disease phenotypes and treatment responses. Cooperative learning, a recently proposed method, unifies the commonly-used fusion approaches, including early and late fusion, and offers a systematic framework for leveraging the shared underlying relationships across omics to strengthen signals. However, the challenge of acquiring large-scale labeled data remains, and there are cases where multiomics data are available but in the absence of annotated labels. To harness the potential of unlabeled multiomcis data, we introduce semi-supervised cooperative learning. By utilizing an "agreement penalty", our method incorporates the additional unlabeled data in the learning process and achieves consistently superior predictive performance on simulated data and a real multiomics study of aging. It offers an effective solution to multiomics data fusion in settings with both labeled and unlabeled data and maximizes the utility of available data resources, with the potential of significantly improving predictive models for diagnostics and therapeutics in an increasingly multiomics world.

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Integrating logical reasoning and machine learning by approximating logical inference with differentiable operators is a widely used technique in Neuro-Symbolic systems. However, some differentiable operators could bring a significant bias during backpropagation and degrade the performance of Neuro-Symbolic learning. In this paper, we reveal that this bias, named \textit{Implication Bias} is common in loss functions derived from fuzzy logic operators. Furthermore, we propose a simple yet effective method to transform the biased loss functions into \textit{Reduced Implication-bias Logic Loss (RILL)} to address the above problem. Empirical study shows that RILL can achieve significant improvements compared with the biased logic loss functions, especially when the knowledge base is incomplete, and keeps more robust than the compared methods when labelled data is insufficient.

The theory underlying robust distributed learning algorithms, designed to resist adversarial machines, matches empirical observations when data is homogeneous. Under data heterogeneity however, which is the norm in practical scenarios, established lower bounds on the learning error are essentially vacuous and greatly mismatch empirical observations. This is because the heterogeneity model considered is too restrictive and does not cover basic learning tasks such as least-squares regression. We consider in this paper a more realistic heterogeneity model, namely (G,B)-gradient dissimilarity, and show that it covers a larger class of learning problems than existing theory. Notably, we show that the breakdown point under heterogeneity is lower than the classical fraction 1/2. We also prove a new lower bound on the learning error of any distributed learning algorithm. We derive a matching upper bound for a robust variant of distributed gradient descent, and empirically show that our analysis reduces the gap between theory and practice.

Ordered sequences of data, specified with a join operation to combine sequences, serve as a foundation for the implementation of parallel functional algorithms. This abstract data type can be elegantly and efficiently implemented using balanced binary trees, where a join operation is provided to combine two trees and rebalance as necessary. In this work, we present a verified implementation and cost analysis of joinable red-black trees in $\textbf{calf}$, a dependent type theory for cost analysis. We implement red-black trees and auxiliary intermediate data structures in such a way that all correctness invariants are intrinsically maintained. Then, we describe and verify precise cost bounds on the operations, making use of the red-black tree invariants. Finally, we implement standard algorithms on sequences using the simple join-based signature and bound their cost in the case that red-black trees are used as the underlying implementation. All proofs are formally mechanized using the embedding of $\textbf{calf}$ in the Agda theorem prover.

Diffusion models have gained prominence in the image domain for their capabilities in data generation and transformation, achieving state-of-the-art performance in various tasks in both image and audio domains. In the rapidly evolving field of audio-based machine learning, safeguarding model integrity and establishing data copyright are of paramount importance. This paper presents the first watermarking technique applied to audio diffusion models trained on mel-spectrograms. This offers a novel approach to the aforementioned challenges. Our model excels not only in benign audio generation, but also incorporates an invisible watermarking trigger mechanism for model verification. This watermark trigger serves as a protective layer, enabling the identification of model ownership and ensuring its integrity. Through extensive experiments, we demonstrate that invisible watermark triggers can effectively protect against unauthorized modifications while maintaining high utility in benign audio generation tasks.

We introduce a general random model of a combinatorial optimization problem with geometric structure that encapsulates both linear programming and integer linear programming. Let $Q$ be a bounded set called the feasible set, $E$ be an arbitrary set called the constraint set, and $A$ be a random linear transform. We introduce and study the $\ell^q$-\textit{margin},$M_q := d_q(AQ, E)$. The margin quantifies the feasibility of finding $y \in AQ$ satisfying the constraint $y \in E$. Our contribution is to establish strong concentration of the margin for any $q \in (2,\infty]$, assuming only that $E$ has permutation symmetry. The case of $q = \infty$ is of particular interest in applications -- specifically to combinatorial ``balancing'' problems -- and is markedly out of the reach of the classical isoperimetric and concentration-of-measure tools that suffice for $q \le 2$. Generality is a key feature of this result: we assume permutation symmetry of the constraint set and nothing else. This allows us to encode many optimization problems in terms of the margin, including random versions of: the closest vector problem, integer linear feasibility, perceptron-type problems, $\ell^q$-combinatorial discrepancy for $2 \le q \le \infty$, and matrix balancing. Concentration of the margin implies a host of new sharp threshold results in these models, and also greatly simplifies and extends some key known results.

Conventional entity typing approaches are based on independent classification paradigms, which make them difficult to recognize inter-dependent, long-tailed and fine-grained entity types. In this paper, we argue that the implicitly entailed extrinsic and intrinsic dependencies between labels can provide critical knowledge to tackle the above challenges. To this end, we propose \emph{Label Reasoning Network(LRN)}, which sequentially reasons fine-grained entity labels by discovering and exploiting label dependencies knowledge entailed in the data. Specifically, LRN utilizes an auto-regressive network to conduct deductive reasoning and a bipartite attribute graph to conduct inductive reasoning between labels, which can effectively model, learn and reason complex label dependencies in a sequence-to-set, end-to-end manner. Experiments show that LRN achieves the state-of-the-art performance on standard ultra fine-grained entity typing benchmarks, and can also resolve the long tail label problem effectively.

Humans perceive the world by concurrently processing and fusing high-dimensional inputs from multiple modalities such as vision and audio. Machine perception models, in stark contrast, are typically modality-specific and optimised for unimodal benchmarks, and hence late-stage fusion of final representations or predictions from each modality (`late-fusion') is still a dominant paradigm for multimodal video classification. Instead, we introduce a novel transformer based architecture that uses `fusion bottlenecks' for modality fusion at multiple layers. Compared to traditional pairwise self-attention, our model forces information between different modalities to pass through a small number of bottleneck latents, requiring the model to collate and condense the most relevant information in each modality and only share what is necessary. We find that such a strategy improves fusion performance, at the same time reducing computational cost. We conduct thorough ablation studies, and achieve state-of-the-art results on multiple audio-visual classification benchmarks including Audioset, Epic-Kitchens and VGGSound. All code and models will be released.

We present self-supervised geometric perception (SGP), the first general framework to learn a feature descriptor for correspondence matching without any ground-truth geometric model labels (e.g., camera poses, rigid transformations). Our first contribution is to formulate geometric perception as an optimization problem that jointly optimizes the feature descriptor and the geometric models given a large corpus of visual measurements (e.g., images, point clouds). Under this optimization formulation, we show that two important streams of research in vision, namely robust model fitting and deep feature learning, correspond to optimizing one block of the unknown variables while fixing the other block. This analysis naturally leads to our second contribution -- the SGP algorithm that performs alternating minimization to solve the joint optimization. SGP iteratively executes two meta-algorithms: a teacher that performs robust model fitting given learned features to generate geometric pseudo-labels, and a student that performs deep feature learning under noisy supervision of the pseudo-labels. As a third contribution, we apply SGP to two perception problems on large-scale real datasets, namely relative camera pose estimation on MegaDepth and point cloud registration on 3DMatch. We demonstrate that SGP achieves state-of-the-art performance that is on-par or superior to the supervised oracles trained using ground-truth labels.

Most object recognition approaches predominantly focus on learning discriminative visual patterns while overlooking the holistic object structure. Though important, structure modeling usually requires significant manual annotations and therefore is labor-intensive. In this paper, we propose to "look into object" (explicitly yet intrinsically model the object structure) through incorporating self-supervisions into the traditional framework. We show the recognition backbone can be substantially enhanced for more robust representation learning, without any cost of extra annotation and inference speed. Specifically, we first propose an object-extent learning module for localizing the object according to the visual patterns shared among the instances in the same category. We then design a spatial context learning module for modeling the internal structures of the object, through predicting the relative positions within the extent. These two modules can be easily plugged into any backbone networks during training and detached at inference time. Extensive experiments show that our look-into-object approach (LIO) achieves large performance gain on a number of benchmarks, including generic object recognition (ImageNet) and fine-grained object recognition tasks (CUB, Cars, Aircraft). We also show that this learning paradigm is highly generalizable to other tasks such as object detection and segmentation (MS COCO). Project page: //github.com/JDAI-CV/LIO.

Object detection typically assumes that training and test data are drawn from an identical distribution, which, however, does not always hold in practice. Such a distribution mismatch will lead to a significant performance drop. In this work, we aim to improve the cross-domain robustness of object detection. We tackle the domain shift on two levels: 1) the image-level shift, such as image style, illumination, etc, and 2) the instance-level shift, such as object appearance, size, etc. We build our approach based on the recent state-of-the-art Faster R-CNN model, and design two domain adaptation components, on image level and instance level, to reduce the domain discrepancy. The two domain adaptation components are based on H-divergence theory, and are implemented by learning a domain classifier in adversarial training manner. The domain classifiers on different levels are further reinforced with a consistency regularization to learn a domain-invariant region proposal network (RPN) in the Faster R-CNN model. We evaluate our newly proposed approach using multiple datasets including Cityscapes, KITTI, SIM10K, etc. The results demonstrate the effectiveness of our proposed approach for robust object detection in various domain shift scenarios.

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