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In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM.We consider the construction of foundational models from the perspectives of dataset construction, model design, and thorough evaluation. Our contribution can be concluded as follows: (i), we construct a large-scale Medical Multi-modal Dataset, MedMD, which consists of 16M 2D and 3D medical scans with high-quality text descriptions or reports across various data formats, modalities, and tasks, covering over 5000 distinct diseases. To the best of our knowledge, this is the first large-scale, high-quality, medical visual-language dataset, with both 2D and 3D scans; (ii ), we propose an architecture that enables visually conditioned generative pre-training, i.e., allowing for integration of text input with 2D or 3D medical scans, and generate responses for diverse radiologic tasks. The model was initially pre-trained on MedMD and subsequently fine-tuned on the domain-specific dataset, which is a radiologic cleaned version of MedMD, containing 3M radiologic visual-language pairs, termed as RadMD; (iii), we propose a new evaluation benchmark, RadBench, that comprises five tasks, including modality recognition, disease diagnosis, visual question answering, report generation and rationale diagnosis, aiming to comprehensively assess the capability of foundation models in handling practical clinical problems. We conduct both automatic and human evaluation on RadBench, in both cases, RadFM significantly outperforms existing multi-modal foundation models. The codes, data, and model checkpoint will all be made publicly available to promote further research and development in the field.

Diffusion models are getting popular in generative image and video synthesis. However, due to the diffusion process, they require a large number of steps to converge. To tackle this issue, in this paper, we propose to perform the diffusion process in the gradient domain, where the convergence becomes faster. There are two reasons. First, thanks to the Poisson equation, the gradient domain is mathematically equivalent to the original image domain. Therefore, each diffusion step in the image domain has a unique corresponding gradient domain representation. Second, the gradient domain is much sparser than the image domain. As a result, gradient domain diffusion models converge faster. Several numerical experiments confirm that the gradient domain diffusion models are more efficient than the original diffusion models. The proposed method can be applied in a wide range of applications such as image processing, computer vision and machine learning tasks.

Robots must make and break contact to interact with the world and perform useful tasks. However, planning and control through contact remains a formidable challenge. In this work, we achieve real-time contact-implicit model predictive control with a surprisingly simple method: inverse dynamics trajectory optimization. While trajectory optimization with inverse dynamics is not new, we introduce a series of incremental innovations that collectively enable fast model predictive control on a variety of challenging manipulation and locomotion tasks. We implement these innovations in an open-source solver, and present a variety of simulation examples to support the effectiveness of the proposed approach. Additionally, we demonstrate contact-implicit model predictive control on hardware at over 100 Hz for a 20 degree-of-freedom bi-manual manipulation task.

To consider model uncertainty in global Fr\'{e}chet regression and improve density response prediction, we propose a frequentist model averaging method. The weights are chosen by minimizing a cross-validation criterion based on Wasserstein distance. In the cases where all candidate models are misspecified, we prove that the corresponding model averaging estimator has asymptotic optimality, achieving the lowest possible Wasserstein distance. When there are correctly specified candidate models, we prove that our method asymptotically assigns all weights to the correctly specified models. Numerical results of extensive simulations and a real data analysis on intracerebral hemorrhage data strongly favour our method.

Serverless computing has become an important model in cloud computing and influenced the design of many applications. Here, we provide our perspective on how the recent landscape of serverless computing for scientific applications looks like. We discuss the advantages and problems with serverless computing for scientific applications, and based on the analysis of existing solutions and approaches, we propose a science-oriented architecture for a serverless computing framework that is based on the existing designs. Finally, we provide an outlook of current trends and future directions.

As surgical interventions trend towards minimally invasive approaches, Concentric Tube Robots (CTRs) have been explored for various interventions such as brain, eye, fetoscopic, lung, cardiac and prostate surgeries. Arranged concentrically, each tube is rotated and translated independently to move the robot end-effector position, making kinematics and control challenging. Classical model-based approaches have been previously investigated with developments in deep learning based approaches outperforming more classical approaches in both forward kinematics and shape estimation. We propose a deep reinforcement learning approach to control where we generalise across two to four systems, an element not yet achieved in any other deep learning approach for CTRs. In this way we explore the likely robustness of the control approach. Also investigated is the impact of rotational constraints applied on tube actuation and the effects on error metrics. We evaluate inverse kinematics errors and tracking error for path following tasks and compare the results to those achieved using state of the art methods. Additionally, as current results are performed in simulation, we also investigate a domain transfer approach known as domain randomization and evaluate error metrics as an initial step towards hardware implementation. Finally, we compare our method to a Jacobian approach found in literature.

LiDAR segmentation is crucial for autonomous driving perception. Recent trends favor point- or voxel-based methods as they often yield better performance than the traditional range view representation. In this work, we unveil several key factors in building powerful range view models. We observe that the "many-to-one" mapping, semantic incoherence, and shape deformation are possible impediments against effective learning from range view projections. We present RangeFormer -- a full-cycle framework comprising novel designs across network architecture, data augmentation, and post-processing -- that better handles the learning and processing of LiDAR point clouds from the range view. We further introduce a Scalable Training from Range view (STR) strategy that trains on arbitrary low-resolution 2D range images, while still maintaining satisfactory 3D segmentation accuracy. We show that, for the first time, a range view method is able to surpass the point, voxel, and multi-view fusion counterparts in the competing LiDAR semantic and panoptic segmentation benchmarks, i.e., SemanticKITTI, nuScenes, and ScribbleKITTI.

Invariant risk minimization (IRM) has recently emerged as a promising alternative for domain generalization. Nevertheless, the loss function is difficult to optimize for nonlinear classifiers and the original optimization objective could fail when pseudo-invariant features and geometric skews exist. Inspired by IRM, in this paper we propose a novel formulation for domain generalization, dubbed invariant information bottleneck (IIB). IIB aims at minimizing invariant risks for nonlinear classifiers and simultaneously mitigating the impact of pseudo-invariant features and geometric skews. Specifically, we first present a novel formulation for invariant causal prediction via mutual information. Then we adopt the variational formulation of the mutual information to develop a tractable loss function for nonlinear classifiers. To overcome the failure modes of IRM, we propose to minimize the mutual information between the inputs and the corresponding representations. IIB significantly outperforms IRM on synthetic datasets, where the pseudo-invariant features and geometric skews occur, showing the effectiveness of proposed formulation in overcoming failure modes of IRM. Furthermore, experiments on DomainBed show that IIB outperforms $13$ baselines by $0.9\%$ on average across $7$ real datasets.

In the era of deep learning, modeling for most NLP tasks has converged to several mainstream paradigms. For example, we usually adopt the sequence labeling paradigm to solve a bundle of tasks such as POS-tagging, NER, Chunking, and adopt the classification paradigm to solve tasks like sentiment analysis. With the rapid progress of pre-trained language models, recent years have observed a rising trend of Paradigm Shift, which is solving one NLP task by reformulating it as another one. Paradigm shift has achieved great success on many tasks, becoming a promising way to improve model performance. Moreover, some of these paradigms have shown great potential to unify a large number of NLP tasks, making it possible to build a single model to handle diverse tasks. In this paper, we review such phenomenon of paradigm shifts in recent years, highlighting several paradigms that have the potential to solve different NLP tasks.

In this paper, we propose a conceptually simple and geometrically interpretable objective function, i.e. additive margin Softmax (AM-Softmax), for deep face verification. In general, the face verification task can be viewed as a metric learning problem, so learning large-margin face features whose intra-class variation is small and inter-class difference is large is of great importance in order to achieve good performance. Recently, Large-margin Softmax and Angular Softmax have been proposed to incorporate the angular margin in a multiplicative manner. In this work, we introduce a novel additive angular margin for the Softmax loss, which is intuitively appealing and more interpretable than the existing works. We also emphasize and discuss the importance of feature normalization in the paper. Most importantly, our experiments on LFW BLUFR and MegaFace show that our additive margin softmax loss consistently performs better than the current state-of-the-art methods using the same network architecture and training dataset. Our code has also been made available at //github.com/happynear/AMSoftmax