In causal inference, it is a fundamental task to estimate the causal effect from observational data. However, latent confounders pose major challenges in causal inference in observational data, for example, confounding bias and M-bias. Recent data-driven causal effect estimators tackle the confounding bias problem via balanced representation learning, but assume no M-bias in the system, thus they fail to handle the M-bias. In this paper, we identify a challenging and unsolved problem caused by a variable that leads to confounding bias and M-bias simultaneously. To address this problem with co-occurring M-bias and confounding bias, we propose a novel Disentangled Latent Representation learning framework for learning latent representations from proxy variables for unbiased Causal effect Estimation (DLRCE) from observational data. Specifically, DLRCE learns three sets of latent representations from the measured proxy variables to adjust for the confounding bias and M-bias. Extensive experiments on both synthetic and three real-world datasets demonstrate that DLRCE significantly outperforms the state-of-the-art estimators in the case of the presence of both confounding bias and M-bias.
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A comprehensive understanding of the organizational principles in the human brain requires, among other factors, well-quantifiable descriptors of nerve fiber architecture. Three-dimensional polarized light imaging (3D-PLI) is a microscopic imaging technique that enables insights into the fine-grained organization of myelinated nerve fibers with high resolution. Descriptors characterizing the fiber architecture observed in 3D-PLI would enable downstream analysis tasks such as multimodal correlation studies, clustering, and mapping. However, best practices for observer-independent characterization of fiber architecture in 3D-PLI are not yet available. To this end, we propose the application of a fully data-driven approach to characterize nerve fiber architecture in 3D-PLI images using self-supervised representation learning. We introduce a 3D-Context Contrastive Learning (CL-3D) objective that utilizes the spatial neighborhood of texture examples across histological brain sections of a 3D reconstructed volume to sample positive pairs for contrastive learning. We combine this sampling strategy with specifically designed image augmentations to gain robustness to typical variations in 3D-PLI parameter maps. The approach is demonstrated for the 3D reconstructed occipital lobe of a vervet monkey brain. We show that extracted features are highly sensitive to different configurations of nerve fibers, yet robust to variations between consecutive brain sections arising from histological processing. We demonstrate their practical applicability for retrieving clusters of homogeneous fiber architecture and performing data mining for interactively selected templates of specific components of fiber architecture such as U-fibers.
Recently, low-resource dialogue state tracking (DST) has received increasing attention. First obtaining state values then based on values to generate slot types has made great progress in this task. However, obtaining state values is still an under-studied problem. Existing extraction-based approaches cannot capture values that require the understanding of context and are not generalizable either. To address these issues, we propose a novel State VAlue Generation based framework (SVAG), decomposing DST into state value generation and domain slot generation. Specifically, we propose to generate state values and use self-training to further improve state value generation. Moreover, we design an estimator aiming at detecting incomplete generation and incorrect generation for pseudo-labeled data selection during self-training. Experimental results on the MultiWOZ 2.1 dataset show that our method which has only less than 1 billion parameters achieves state-of-the-art performance under the data ratio settings of 5%, 10%, and 25% when limited to models under 100 billion parameters. Compared to models with more than 100 billion parameters, SVAG still reaches competitive results.
Missing data is a pernicious problem in epidemiologic research. Research on the validity of complete case analysis for missing data has typically focused on estimating the average treatment effect (ATE) in the whole population. However, other target populations like the treated (ATT) or external targets can be of substantive interest. In such cases, whether missing covariate data occurs within or outside the target population may impact the validity of complete case analysis. We sought to assess bias in complete case analysis when covariate data is missing outside the target (e.g., missing covariate data among the untreated when estimating the ATT). We simulated a study of the effect of a binary treatment X on a binary outcome Y in the presence of 3 confounders C1-C3 that modified the risk difference (RD). We induced missingness in C1 only among the untreated under 4 scenarios: completely randomly (similar to MCAR); randomly based on C2 and C3 (similar to MAR); randomly based on C1 (similar to MNAR); or randomly based on Y (similar to MAR). We estimated the ATE and ATT using weighting and averaged results across the replicates. We conducted a parallel simulation transporting trial results to a target population in the presence of missing covariate data in the trial. In the complete case analysis, estimated ATE was unbiased only when C1 was MCAR among the untreated. The estimated ATT, on the other hand, was unbiased in all scenarios except when Y caused missingness. The parallel simulation of generalizing and transporting trial results saw similar bias patterns. If missing covariate data is only present outside the target population, complete case analysis is unbiased except when missingness is associated with the outcome.
The assumption that data are invariant under the action of a compact group is implicit in many statistical modeling assumptions such as normality, or the assumption of independence and identical distributions. Hence, testing for the presence of such invariances offers a principled way to falsify various statistical models. In this article, we develop sequential, anytime-valid tests of distributional symmetry under the action of general compact groups. The tests that are developed allow for the continuous monitoring of data as it is collected while keeping type-I error guarantees, and include tests for exchangeability and rotational symmetry as special examples. The main tool to this end is the machinery developed for conformal prediction. The resulting test statistic, called a conformal martingale, can be interpreted as a likelihood ratio. We use this interpretation to show that the test statistics are optimal -- in a specific log-optimality sense -- against certain alternatives. Furthermore, we draw a connection between conformal prediction, anytime-valid tests of distributional invariance, and current developments on anytime-valid testing. In particular, we extend existing anytime-valid tests of independence, which leverage exchangeability, to work under general group invariances. Additionally, we discuss testing for invariance under subgroups of the permutation group and orthogonal group, the latter of which corresponds to testing the assumptions behind linear regression models.
Solving partially observable Markov decision processes (POMDPs) with high dimensional and continuous observations, such as camera images, is required for many real life robotics and planning problems. Recent researches suggested machine learned probabilistic models as observation models, but their use is currently too computationally expensive for online deployment. We deal with the question of what would be the implication of using simplified observation models for planning, while retaining formal guarantees on the quality of the solution. Our main contribution is a novel probabilistic bound based on a statistical total variation distance of the simplified model. We show that it bounds the theoretical POMDP value w.r.t. original model, from the empirical planned value with the simplified model, by generalizing recent results of particle-belief MDP concentration bounds. Our calculations can be separated into offline and online parts, and we arrive at formal guarantees without having to access the costly model at all during planning, which is also a novel result. Finally, we demonstrate in simulation how to integrate the bound into the routine of an existing continuous online POMDP solver.
Causal effect estimation from observational data is a fundamental task in empirical sciences. It becomes particularly challenging when unobserved confounders are involved in a system. This paper focuses on front-door adjustment -- a classic technique which, using observed mediators allows to identify causal effects even in the presence of unobserved confounding. While the statistical properties of the front-door estimation are quite well understood, its algorithmic aspects remained unexplored for a long time. In 2022, Jeong, Tian, and Bareinboim presented the first polynomial-time algorithm for finding sets satisfying the front-door criterion in a given directed acyclic graph (DAG), with an $O(n^3(n+m))$ run time, where $n$ denotes the number of variables and $m$ the number of edges of the causal graph. In our work, we give the first linear-time, i.e., $O(n+m)$, algorithm for this task, which thus reaches the asymptotically optimal time complexity. This result implies an $O(n(n+m))$ delay enumeration algorithm of all front-door adjustment sets, again improving previous work by a factor of $n^3$. Moreover, we provide the first linear-time algorithm for finding a minimal front-door adjustment set. We offer implementations of our algorithms in multiple programming languages to facilitate practical usage and empirically validate their feasibility, even for large graphs.
Recently, the emergence of a large number of Synthetic Aperture Radar (SAR) sensors and target datasets has made it possible to unify downstream tasks with self-supervised learning techniques, which can pave the way for building the foundation model in the SAR target recognition field. The major challenge of self-supervised learning for SAR target recognition lies in the generalizable representation learning in low data quality and noise.To address the aforementioned problem, we propose a knowledge-guided predictive architecture that uses local masked patches to predict the multiscale SAR feature representations of unseen context. The core of the proposed architecture lies in combining traditional SAR domain feature extraction with state-of-the-art scalable self-supervised learning for accurate generalized feature representations. The proposed framework is validated on various downstream datasets (MSTAR, FUSAR-Ship, SAR-ACD and SSDD), and can bring consistent performance improvement for SAR target recognition. The experimental results strongly demonstrate the unified performance improvement of the self-supervised learning technique for SAR target recognition across diverse targets, scenes and sensors.
Randomized controlled trials (RCTs) serve as the cornerstone for understanding causal effects, yet extending inferences to target populations presents challenges due to effect heterogeneity and underrepresentation. Our paper addresses the critical issue of identifying and characterizing underrepresented subgroups in RCTs, proposing a novel framework for refining target populations to improve generalizability. We introduce an optimization-based approach, Rashomon Set of Optimal Trees (ROOT), to characterize underrepresented groups. ROOT optimizes the target subpopulation distribution by minimizing the variance of the target average treatment effect estimate, ensuring more precise treatment effect estimations. Notably, ROOT generates interpretable characteristics of the underrepresented population, aiding researchers in effective communication. Our approach demonstrates improved precision and interpretability compared to alternatives, as illustrated with synthetic data experiments. We apply our methodology to extend inferences from the Starting Treatment with Agonist Replacement Therapies (START) trial -- investigating the effectiveness of medication for opioid use disorder -- to the real-world population represented by the Treatment Episode Dataset: Admissions (TEDS-A). By refining target populations using ROOT, our framework offers a systematic approach to enhance decision-making accuracy and inform future trials in diverse populations.
In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.
Object detection typically assumes that training and test data are drawn from an identical distribution, which, however, does not always hold in practice. Such a distribution mismatch will lead to a significant performance drop. In this work, we aim to improve the cross-domain robustness of object detection. We tackle the domain shift on two levels: 1) the image-level shift, such as image style, illumination, etc, and 2) the instance-level shift, such as object appearance, size, etc. We build our approach based on the recent state-of-the-art Faster R-CNN model, and design two domain adaptation components, on image level and instance level, to reduce the domain discrepancy. The two domain adaptation components are based on H-divergence theory, and are implemented by learning a domain classifier in adversarial training manner. The domain classifiers on different levels are further reinforced with a consistency regularization to learn a domain-invariant region proposal network (RPN) in the Faster R-CNN model. We evaluate our newly proposed approach using multiple datasets including Cityscapes, KITTI, SIM10K, etc. The results demonstrate the effectiveness of our proposed approach for robust object detection in various domain shift scenarios.
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