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The capabilities of large language models (LLMs) have been progressing at a breathtaking speed, leaving even their own developers grappling with the depth of their potential and risks. While initial steps have been taken to evaluate the safety and alignment of general-knowledge LLMs, exposing some weaknesses, to our knowledge, the safety and alignment of medical LLMs has not been evaluated despite their risks for personal health and safety, public health and safety, and human rights. To this end, we carry out the first safety evaluation for medical LLMs. Specifically, we set forth a definition of medical safety and alignment for medical artificial intelligence systems, develop a dataset of harmful medical questions to evaluate the medical safety and alignment of an LLM, evaluate both general and medical safety and alignment of medical LLMs, demonstrate fine-tuning as an effective mitigation strategy, and discuss broader, large-scale approaches used by the machine learning community to develop safe and aligned LLMs. We hope that this work casts light on the safety and alignment of medical LLMs and motivates future work to study it and develop additional mitigation strategies, minimizing the risks of harm of LLMs in medicine.

With growing popularity, deep learning (DL) models are becoming larger-scale, and only the companies with vast training datasets and immense computing power can manage their business serving such large models. Most of those DL models are proprietary to the companies who thus strive to keep their private models safe from the model extraction attack (MEA), whose aim is to steal the model by training surrogate models. Nowadays, companies are inclined to offload the models from central servers to edge/endpoint devices. As revealed in the latest studies, adversaries exploit this opportunity as new attack vectors to launch side-channel attack (SCA) on the device running victim model and obtain various pieces of the model information, such as the model architecture (MA) and image dimension (ID). Our work provides a comprehensive understanding of such a relationship for the first time and would benefit future MEA studies in both offensive and defensive sides in that they may learn which pieces of information exposed by SCA are more important than the others. Our analysis additionally reveals that by grasping the victim model information from SCA, MEA can get highly effective and successful even without any prior knowledge of the model. Finally, to evince the practicality of our analysis results, we empirically apply SCA, and subsequently, carry out MEA under realistic threat assumptions. The results show up to 5.8 times better performance than when the adversary has no model information about the victim model.

Fast-evolving artificial intelligence (AI) algorithms such as large language models have been driving the ever-increasing computing demands in today's data centers. Heterogeneous computing with domain-specific architectures (DSAs) brings many opportunities when scaling up and scaling out the computing system. In particular, heterogeneous chiplet architecture is favored to keep scaling up and scaling out the system as well as to reduce the design complexity and the cost stemming from the traditional monolithic chip design. However, how to interconnect computing resources and orchestrate heterogeneous chiplets is the key to success. In this paper, we first discuss the diversity and evolving demands of different AI workloads. We discuss how chiplet brings better cost efficiency and shorter time to market. Then we discuss the challenges in establishing chiplet interface standards, packaging, and security issues. We further discuss the software programming challenges in chiplet systems.

Diffusion models are a powerful class of generative models which simulate stochastic differential equations (SDEs) to generate data from noise. While diffusion models have achieved remarkable progress, they have limitations in unpaired image-to-image (I2I) translation tasks due to the Gaussian prior assumption. Schr\"{o}dinger Bridge (SB), which learns an SDE to translate between two arbitrary distributions, have risen as an attractive solution to this problem. Yet, to our best knowledge, none of SB models so far have been successful at unpaired translation between high-resolution images. In this work, we propose Unpaired Neural Schr\"{o}dinger Bridge (UNSB), which expresses the SB problem as a sequence of adversarial learning problems. This allows us to incorporate advanced discriminators and regularization to learn a SB between unpaired data. We show that UNSB is scalable and successfully solves various unpaired I2I translation tasks. Code: \url{//github.com/cyclomon/UNSB}

Integer linear programming (ILP) models a wide range of practical combinatorial optimization problems and significantly impacts industry and management sectors. This work proposes new characterizations of ILP with the concept of boundary solutions. Motivated by the new characterizations, we develop a new local search algorithm Local-ILP, which is efficient for solving general ILP validated on a large heterogeneous problem dataset. We propose a new local search framework that switches between three modes, namely Search, Improve, and Restore modes. Two new operators are proposed, namely the tight move and the lift move operators, which are associated with appropriate scoring functions. Different modes apply different operators to realize different search strategies and the algorithm switches between three modes according to the current search state. Putting these together, we develop a local search ILP solver called Local-ILP. Experiments conducted on the MIPLIB dataset show the effectiveness of our algorithm in solving large-scale hard ILP problems. In the aspect of finding a good feasible solution quickly, Local-ILP is competitive and complementary to the state-of-the-art commercial solver Gurobi and significantly outperforms the state-of-the-art non-commercial solver SCIP. Moreover, our algorithm establishes new records for 6 MIPLIB open instances. The theoretical analysis of our algorithm is also presented, which shows our algorithm could avoid visiting unnecessary regions.

Conventional methods for object detection typically require a substantial amount of training data and preparing such high-quality training data is very labor-intensive. In this paper, we propose a novel few-shot object detection network that aims at detecting objects of unseen categories with only a few annotated examples. Central to our method are our Attention-RPN, Multi-Relation Detector and Contrastive Training strategy, which exploit the similarity between the few shot support set and query set to detect novel objects while suppressing false detection in the background. To train our network, we contribute a new dataset that contains 1000 categories of various objects with high-quality annotations. To the best of our knowledge, this is one of the first datasets specifically designed for few-shot object detection. Once our few-shot network is trained, it can detect objects of unseen categories without further training or fine-tuning. Our method is general and has a wide range of potential applications. We produce a new state-of-the-art performance on different datasets in the few-shot setting. The dataset link is //github.com/fanq15/Few-Shot-Object-Detection-Dataset.

Pre-trained deep neural network language models such as ELMo, GPT, BERT and XLNet have recently achieved state-of-the-art performance on a variety of language understanding tasks. However, their size makes them impractical for a number of scenarios, especially on mobile and edge devices. In particular, the input word embedding matrix accounts for a significant proportion of the model's memory footprint, due to the large input vocabulary and embedding dimensions. Knowledge distillation techniques have had success at compressing large neural network models, but they are ineffective at yielding student models with vocabularies different from the original teacher models. We introduce a novel knowledge distillation technique for training a student model with a significantly smaller vocabulary as well as lower embedding and hidden state dimensions. Specifically, we employ a dual-training mechanism that trains the teacher and student models simultaneously to obtain optimal word embeddings for the student vocabulary. We combine this approach with learning shared projection matrices that transfer layer-wise knowledge from the teacher model to the student model. Our method is able to compress the BERT_BASE model by more than 60x, with only a minor drop in downstream task metrics, resulting in a language model with a footprint of under 7MB. Experimental results also demonstrate higher compression efficiency and accuracy when compared with other state-of-the-art compression techniques.

We introduce a multi-task setup of identifying and classifying entities, relations, and coreference clusters in scientific articles. We create SciERC, a dataset that includes annotations for all three tasks and develop a unified framework called Scientific Information Extractor (SciIE) for with shared span representations. The multi-task setup reduces cascading errors between tasks and leverages cross-sentence relations through coreference links. Experiments show that our multi-task model outperforms previous models in scientific information extraction without using any domain-specific features. We further show that the framework supports construction of a scientific knowledge graph, which we use to analyze information in scientific literature.

High spectral dimensionality and the shortage of annotations make hyperspectral image (HSI) classification a challenging problem. Recent studies suggest that convolutional neural networks can learn discriminative spatial features, which play a paramount role in HSI interpretation. However, most of these methods ignore the distinctive spectral-spatial characteristic of hyperspectral data. In addition, a large amount of unlabeled data remains an unexploited gold mine for efficient data use. Therefore, we proposed an integration of generative adversarial networks (GANs) and probabilistic graphical models for HSI classification. Specifically, we used a spectral-spatial generator and a discriminator to identify land cover categories of hyperspectral cubes. Moreover, to take advantage of a large amount of unlabeled data, we adopted a conditional random field to refine the preliminary classification results generated by GANs. Experimental results obtained using two commonly studied datasets demonstrate that the proposed framework achieved encouraging classification accuracy using a small number of data for training.

In this paper, we propose the joint learning attention and recurrent neural network (RNN) models for multi-label classification. While approaches based on the use of either model exist (e.g., for the task of image captioning), training such existing network architectures typically require pre-defined label sequences. For multi-label classification, it would be desirable to have a robust inference process, so that the prediction error would not propagate and thus affect the performance. Our proposed model uniquely integrates attention and Long Short Term Memory (LSTM) models, which not only addresses the above problem but also allows one to identify visual objects of interests with varying sizes without the prior knowledge of particular label ordering. More importantly, label co-occurrence information can be jointly exploited by our LSTM model. Finally, by advancing the technique of beam search, prediction of multiple labels can be efficiently achieved by our proposed network model.