Accurate predictions, as with machine learning, may not suffice to provide optimal healthcare for every patient. Indeed, prediction can be driven by shortcuts in the data, such as racial biases. Causal thinking is needed for data-driven decisions. Here, we give an introduction to the key elements, focusing on routinely-collected data, electronic health records (EHRs) and claims data. Using such data to assess the value of an intervention requires care: temporal dependencies and existing practices easily confound the causal effect. We present a step-by-step framework to help build valid decision making from real-life patient records by emulating a randomized trial before individualizing decisions, eg with machine learning. Our framework highlights the most important pitfalls and considerations in analysing EHRs or claims data to draw causal conclusions. We illustrate the various choices in studying the effect of albumin on sepsis mortality in the Medical Information Mart for Intensive Care database (MIMIC-IV). We study the impact of various choices at every step, from feature extraction to causal-estimator selection. In a tutorial spirit, the code and the data are openly available.
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Recently, there has been a growing focus and interest in applying machine learning (ML) to the field of cybersecurity, particularly in malware detection and prevention. Several research works on malware analysis have been proposed, offering promising results for both academic and practical applications. In these works, the use of Generative Adversarial Networks (GANs) or Reinforcement Learning (RL) can aid malware creators in crafting metamorphic malware that evades antivirus software. In this study, we propose a mutation system to counteract ensemble learning-based detectors by combining GANs and an RL model, overcoming the limitations of the MalGAN model. Our proposed FeaGAN model is built based on MalGAN by incorporating an RL model called the Deep Q-network anti-malware Engines Attacking Framework (DQEAF). The RL model addresses three key challenges in performing adversarial attacks on Windows Portable Executable malware, including format preservation, executability preservation, and maliciousness preservation. In the FeaGAN model, ensemble learning is utilized to enhance the malware detector's evasion ability, with the generated adversarial patterns. The experimental results demonstrate that 100\% of the selected mutant samples preserve the format of executable files, while certain successes in both executability preservation and maliciousness preservation are achieved, reaching a stable success rate.
It is a long-standing desire of industry and research to automate the software development and testing process as much as possible. In this process, requirements engineering (RE) plays a fundamental role for all other steps that build on it. Model-based design and testing methods have been developed to handle the growing complexity and variability of software systems. However, major effort is still required to create specification models from a large set of functional requirements provided in natural language. Numerous approaches based on natural language processing (NLP) have been proposed in the literature to generate requirements models using mainly syntactic properties. Recent advances in NLP show that semantic quantities can also be identified and used to provide better assistance in the requirements formalization process. In this work, we present and discuss principal ideas and state-of-the-art methodologies from the field of NLP in order to guide the readers on how to create a set of rules and methods for the semi-automated formalization of requirements according to their specific use case and needs. We discuss two different approaches in detail and highlight the iterative development of rule sets. The requirements models are represented in a human- and machine-readable format in the form of pseudocode. The presented methods are demonstrated on two industrial use cases from the automotive and railway domains. It shows that using current pre-trained NLP models requires less effort to create a set of rules and can be easily adapted to specific use cases and domains. In addition, findings and shortcomings of this research area are highlighted and an outlook on possible future developments is given.
Multimodal medical data fusion has emerged as a transformative approach in smart healthcare, enabling a comprehensive understanding of patient health and personalized treatment plans. In this paper, a journey from data to information to knowledge to wisdom (DIKW) is explored through multimodal fusion for smart healthcare. We present a comprehensive review of multimodal medical data fusion focused on the integration of various data modalities. The review explores different approaches such as feature selection, rule-based systems, machine learning, deep learning, and natural language processing, for fusing and analyzing multimodal data. This paper also highlights the challenges associated with multimodal fusion in healthcare. By synthesizing the reviewed frameworks and theories, it proposes a generic framework for multimodal medical data fusion that aligns with the DIKW model. Moreover, it discusses future directions related to the four pillars of healthcare: Predictive, Preventive, Personalized, and Participatory approaches. The components of the comprehensive survey presented in this paper form the foundation for more successful implementation of multimodal fusion in smart healthcare. Our findings can guide researchers and practitioners in leveraging the power of multimodal fusion with the state-of-the-art approaches to revolutionize healthcare and improve patient outcomes.
With the advent of the IoT, AI and ML/DL algorithms, the landscape of data-driven medical applications has emerged as a promising avenue for designing robust and scalable diagnostic and prognostic models from medical data. Consequently, the realm of data-driven medical applications has garnered significant attention spanning academia and industry, ushering in marked enhancements in healthcare delivery quality. Despite these strides, the adoption of AI-driven medical applications remains hindered by formidable challenges, including the arduous task of meeting security, privacy, and quality of service (QoS) standards. Recent developments in federated learning have made it possible to train complex machine-learned models in a distributed manner and has become an active research domain, particularly processing the medical data at the edge of the network in a decentralized way to preserve privacy and address security concerns. To this end, this survey paper highlights the current and future of FL technology in medical applications where data sharing is a significant burden. We delve into the contemporary research trends and their outcomes, unravelling the intricacies of designing reliable and scalable FL models. Our survey outlines the foundational statistical predicaments of FL, confronts device-related obstacles, delves into security challenges, and navigates the intricate terrain of privacy concerns, all while spotlighting its transformative potential within the medical domain. A primary focus of our study rests on medical applications, where we underscore the weighty burden of global cancer and illuminate the potency of FL in engendering computer-aided diagnosis tools that address this challenge with heightened efficacy.
In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.
In contrast to batch learning where all training data is available at once, continual learning represents a family of methods that accumulate knowledge and learn continuously with data available in sequential order. Similar to the human learning process with the ability of learning, fusing, and accumulating new knowledge coming at different time steps, continual learning is considered to have high practical significance. Hence, continual learning has been studied in various artificial intelligence tasks. In this paper, we present a comprehensive review of the recent progress of continual learning in computer vision. In particular, the works are grouped by their representative techniques, including regularization, knowledge distillation, memory, generative replay, parameter isolation, and a combination of the above techniques. For each category of these techniques, both its characteristics and applications in computer vision are presented. At the end of this overview, several subareas, where continuous knowledge accumulation is potentially helpful while continual learning has not been well studied, are discussed.
Influenced by the stunning success of deep learning in computer vision and language understanding, research in recommendation has shifted to inventing new recommender models based on neural networks. In recent years, we have witnessed significant progress in developing neural recommender models, which generalize and surpass traditional recommender models owing to the strong representation power of neural networks. In this survey paper, we conduct a systematic review on neural recommender models, aiming to summarize the field to facilitate future progress. Distinct from existing surveys that categorize existing methods based on the taxonomy of deep learning techniques, we instead summarize the field from the perspective of recommendation modeling, which could be more instructive to researchers and practitioners working on recommender systems. Specifically, we divide the work into three types based on the data they used for recommendation modeling: 1) collaborative filtering models, which leverage the key source of user-item interaction data; 2) content enriched models, which additionally utilize the side information associated with users and items, like user profile and item knowledge graph; and 3) context enriched models, which account for the contextual information associated with an interaction, such as time, location, and the past interactions. After reviewing representative works for each type, we finally discuss some promising directions in this field, including benchmarking recommender systems, graph reasoning based recommendation models, and explainable and fair recommendations for social good.
Deep learning techniques have received much attention in the area of image denoising. However, there are substantial differences in the various types of deep learning methods dealing with image denoising. Specifically, discriminative learning based on deep learning can ably address the issue of Gaussian noise. Optimization models based on deep learning are effective in estimating the real noise. However, there has thus far been little related research to summarize the different deep learning techniques for image denoising. In this paper, we offer a comparative study of deep techniques in image denoising. We first classify the deep convolutional neural networks (CNNs) for additive white noisy images; the deep CNNs for real noisy images; the deep CNNs for blind denoising and the deep CNNs for hybrid noisy images, which represents the combination of noisy, blurred and low-resolution images. Then, we analyze the motivations and principles of the different types of deep learning methods. Next, we compare the state-of-the-art methods on public denoising datasets in terms of quantitative and qualitative analysis. Finally, we point out some potential challenges and directions of future research.
With the advent of deep neural networks, learning-based approaches for 3D reconstruction have gained popularity. However, unlike for images, in 3D there is no canonical representation which is both computationally and memory efficient yet allows for representing high-resolution geometry of arbitrary topology. Many of the state-of-the-art learning-based 3D reconstruction approaches can hence only represent very coarse 3D geometry or are limited to a restricted domain. In this paper, we propose occupancy networks, a new representation for learning-based 3D reconstruction methods. Occupancy networks implicitly represent the 3D surface as the continuous decision boundary of a deep neural network classifier. In contrast to existing approaches, our representation encodes a description of the 3D output at infinite resolution without excessive memory footprint. We validate that our representation can efficiently encode 3D structure and can be inferred from various kinds of input. Our experiments demonstrate competitive results, both qualitatively and quantitatively, for the challenging tasks of 3D reconstruction from single images, noisy point clouds and coarse discrete voxel grids. We believe that occupancy networks will become a useful tool in a wide variety of learning-based 3D tasks.
Object detection typically assumes that training and test data are drawn from an identical distribution, which, however, does not always hold in practice. Such a distribution mismatch will lead to a significant performance drop. In this work, we aim to improve the cross-domain robustness of object detection. We tackle the domain shift on two levels: 1) the image-level shift, such as image style, illumination, etc, and 2) the instance-level shift, such as object appearance, size, etc. We build our approach based on the recent state-of-the-art Faster R-CNN model, and design two domain adaptation components, on image level and instance level, to reduce the domain discrepancy. The two domain adaptation components are based on H-divergence theory, and are implemented by learning a domain classifier in adversarial training manner. The domain classifiers on different levels are further reinforced with a consistency regularization to learn a domain-invariant region proposal network (RPN) in the Faster R-CNN model. We evaluate our newly proposed approach using multiple datasets including Cityscapes, KITTI, SIM10K, etc. The results demonstrate the effectiveness of our proposed approach for robust object detection in various domain shift scenarios.
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