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Despite the availability of large amounts of genomics data, medical treatment recommendations have not successfully used them. In this paper, we consider the utility of high dimensional genomic-clinical data and nonparametric methods for making cancer treatment recommendations. This builds upon the framework of the individualized treatment rule [Qian and Murphy 2011] but we aim to overcome their method's limitations, specifically in the instances when the method encounters a large number of covariates and an issue of model misspecification. We tackle this problem using a dimension reduction method, namely Sliced Inverse Regression (SIR, [Li 1991]), with a rich class of models for the treatment response. Notably, SIR defines a feature space for high-dimensional data, offering an advantage similar to those found in the popular neural network models. With the features obtained from SIR, a simple visualization is used to compare different treatment options and present the recommended treatment. Additionally, we derive the consistency and the convergence rate of the proposed recommendation approach through a value function. The effectiveness of the proposed approach is demonstrated through simulation studies and the promising results from a real-data example of the treatment of multiple myeloma.

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ACM/IEEE第23屆模型驅動工程語言和系統國際會議,是模型驅動軟件和系統工程的首要會議系列,由ACM-SIGSOFT和IEEE-TCSE支持組織。自1998年以來,模型涵蓋了建模的各個方面,從語言和方法到工具和應用程序。模特的參加者來自不同的背景,包括研究人員、學者、工程師和工業專業人士。MODELS 2019是一個論壇,參與者可以圍繞建模和模型驅動的軟件和系統交流前沿研究成果和創新實踐經驗。今年的版本將為建模社區提供進一步推進建模基礎的機會,并在網絡物理系統、嵌入式系統、社會技術系統、云計算、大數據、機器學習、安全、開源等新興領域提出建模的創新應用以及可持續性。 官網鏈接: · 代碼 · 模型評估 · 模式識別 · Performer ·
2022 年 4 月 20 日

Modern code review is a critical and indispensable practice in a pull-request development paradigm that prevails in Open Source Software (OSS) development. Finding a suitable reviewer in projects with massive participants thus becomes an increasingly challenging task. Many reviewer recommendation approaches (recommenders) have been developed to support this task which apply a similar strategy, i.e. modeling the review history first then followed by predicting/recommending a reviewer based on the model. Apparently, the better the model reflects the reality in review history, the higher recommender's performance we may expect. However, one typical scenario in a pull-request development paradigm, i.e. one Pull-Request (PR) (such as a revision or addition submitted by a contributor) may have multiple reviewers and they may impact each other through publicly posted comments, has not been modeled well in existing recommenders. We adopted the hypergraph technique to model this high-order relationship (i.e. one PR with multiple reviewers herein) and developed a new recommender, namely HGRec, which is evaluated by 12 OSS projects with more than 87K PRs, 680K comments in terms of accuracy and recommendation distribution. The results indicate that HGRec outperforms the state-of-the-art recommenders on recommendation accuracy. Besides, among the top three accurate recommenders, HGRec is more likely to recommend a diversity of reviewers, which can help to relieve the core reviewers' workload congestion issue. Moreover, since HGRec is based on hypergraph, which is a natural and interpretable representation to model review history, it is easy to accommodate more types of entities and realistic relationships in modern code review scenarios. As the first attempt, this study reveals the potentials of hypergraph on advancing the pragmatic solutions for code reviewer recommendation.

In this work, we aim to consider the application of contrastive learning in the scenario of the recommendation system adequately, making it more suitable for recommendation task. We propose a learning paradigm called supervised contrastive learning(SCL) to support the graph convolutional neural network. Specifically, we will calculate the similarity between different nodes in user side and item side respectively during data preprocessing, and then when applying contrastive learning, not only will the augmented views be regarded as the positive samples, but also a certain number of similar samples will be regarded as the positive samples, which is different with SimCLR that treats other samples in a batch as negative samples. We apply SCL on the most advanced LightGCN. In addition, in order to consider the uncertainty of node interaction, we also propose a new data augment method called node replication. Empirical research and ablation study on Gowalla, Yelp2018, Amazon-Book datasets prove the effectiveness of SCL and node replication, which improve the accuracy of recommendations and robustness to interactive noise.

A knowledge graph (KG) consists of a set of interconnected typed entities and their attributes. Recently, KGs are popularly used as the auxiliary information to enable more accurate, explainable, and diverse user preference recommendations. Specifically, existing KG-based recommendation methods target modeling high-order relations/dependencies from long connectivity user-item interactions hidden in KG. However, most of them ignore the cold-start problems (i.e., user cold-start and item cold-start) of recommendation analytics, which restricts their performance in scenarios when involving new users or new items. Inspired by the success of meta-learning on scarce training samples, we propose a novel meta-learning based framework called MetaKG, which encompasses a collaborative-aware meta learner and a knowledge-aware meta learner, to capture meta users' preference and entities' knowledge for cold-start recommendations. The collaborative-aware meta learner aims to locally aggregate user preferences for each user preference learning task. In contrast, the knowledge-aware meta learner is to globally generalize knowledge representation across different user preference learning tasks. Guided by two meta learners, MetaKG can effectively capture the high-order collaborative relations and semantic representations, which could be easily adapted to cold-start scenarios. Besides, we devise a novel adaptive task scheduler which can adaptively select the informative tasks for meta learning in order to prevent the model from being corrupted by noisy tasks. Extensive experiments on various cold-start scenarios using three real data sets demonstrate that our presented MetaKG outperforms all the existing state-of-the-art competitors in terms of effectiveness, efficiency, and scalability.

Sequential recommendation as an emerging topic has attracted increasing attention due to its important practical significance. Models based on deep learning and attention mechanism have achieved good performance in sequential recommendation. Recently, the generative models based on Variational Autoencoder (VAE) have shown the unique advantage in collaborative filtering. In particular, the sequential VAE model as a recurrent version of VAE can effectively capture temporal dependencies among items in user sequence and perform sequential recommendation. However, VAE-based models suffer from a common limitation that the representational ability of the obtained approximate posterior distribution is limited, resulting in lower quality of generated samples. This is especially true for generating sequences. To solve the above problem, in this work, we propose a novel method called Adversarial and Contrastive Variational Autoencoder (ACVAE) for sequential recommendation. Specifically, we first introduce the adversarial training for sequence generation under the Adversarial Variational Bayes (AVB) framework, which enables our model to generate high-quality latent variables. Then, we employ the contrastive loss. The latent variables will be able to learn more personalized and salient characteristics by minimizing the contrastive loss. Besides, when encoding the sequence, we apply a recurrent and convolutional structure to capture global and local relationships in the sequence. Finally, we conduct extensive experiments on four real-world datasets. The experimental results show that our proposed ACVAE model outperforms other state-of-the-art methods.

Graph Convolution Networks (GCNs) manifest great potential in recommendation. This is attributed to their capability on learning good user and item embeddings by exploiting the collaborative signals from the high-order neighbors. Like other GCN models, the GCN based recommendation models also suffer from the notorious over-smoothing problem - when stacking more layers, node embeddings become more similar and eventually indistinguishable, resulted in performance degradation. The recently proposed LightGCN and LR-GCN alleviate this problem to some extent, however, we argue that they overlook an important factor for the over-smoothing problem in recommendation, that is, high-order neighboring users with no common interests of a user can be also involved in the user's embedding learning in the graph convolution operation. As a result, the multi-layer graph convolution will make users with dissimilar interests have similar embeddings. In this paper, we propose a novel Interest-aware Message-Passing GCN (IMP-GCN) recommendation model, which performs high-order graph convolution inside subgraphs. The subgraph consists of users with similar interests and their interacted items. To form the subgraphs, we design an unsupervised subgraph generation module, which can effectively identify users with common interests by exploiting both user feature and graph structure. To this end, our model can avoid propagating negative information from high-order neighbors into embedding learning. Experimental results on three large-scale benchmark datasets show that our model can gain performance improvement by stacking more layers and outperform the state-of-the-art GCN-based recommendation models significantly.

Collaborative filtering often suffers from sparsity and cold start problems in real recommendation scenarios, therefore, researchers and engineers usually use side information to address the issues and improve the performance of recommender systems. In this paper, we consider knowledge graphs as the source of side information. We propose MKR, a Multi-task feature learning approach for Knowledge graph enhanced Recommendation. MKR is a deep end-to-end framework that utilizes knowledge graph embedding task to assist recommendation task. The two tasks are associated by cross&compress units, which automatically share latent features and learn high-order interactions between items in recommender systems and entities in the knowledge graph. We prove that cross&compress units have sufficient capability of polynomial approximation, and show that MKR is a generalized framework over several representative methods of recommender systems and multi-task learning. Through extensive experiments on real-world datasets, we demonstrate that MKR achieves substantial gains in movie, book, music, and news recommendation, over state-of-the-art baselines. MKR is also shown to be able to maintain a decent performance even if user-item interactions are sparse.

Providing model-generated explanations in recommender systems is important to user experience. State-of-the-art recommendation algorithms -- especially the collaborative filtering (CF) based approaches with shallow or deep models -- usually work with various unstructured information sources for recommendation, such as textual reviews, visual images, and various implicit or explicit feedbacks. Though structured knowledge bases were considered in content-based approaches, they have been largely ignored recently due to the availability of vast amount of data and the learning power of many complex models. However, structured knowledge bases exhibit unique advantages in personalized recommendation systems. When the explicit knowledge about users and items is considered for recommendation, the system could provide highly customized recommendations based on users' historical behaviors and the knowledge is helpful for providing informed explanations regarding the recommended items. In this work, we propose to reason over knowledge base embeddings for explainable recommendation. Specifically, we propose a knowledge base representation learning framework to embed heterogeneous entities for recommendation, and based on the embedded knowledge base, a soft matching algorithm is proposed to generate personalized explanations for the recommended items. Experimental results on real-world e-commerce datasets verified the superior recommendation performance and the explainability power of our approach compared with state-of-the-art baselines.

The cross-domain recommendation technique is an effective way of alleviating the data sparsity in recommender systems by leveraging the knowledge from relevant domains. Transfer learning is a class of algorithms underlying these techniques. In this paper, we propose a novel transfer learning approach for cross-domain recommendation by using neural networks as the base model. We assume that hidden layers in two base networks are connected by cross mappings, leading to the collaborative cross networks (CoNet). CoNet enables dual knowledge transfer across domains by introducing cross connections from one base network to another and vice versa. CoNet is achieved in multi-layer feedforward networks by adding dual connections and joint loss functions, which can be trained efficiently by back-propagation. The proposed model is evaluated on two real-world datasets and it outperforms baseline models by relative improvements of 3.56\% in MRR and 8.94\% in NDCG, respectively.

State-of-the-art recommendation algorithms -- especially the collaborative filtering (CF) based approaches with shallow or deep models -- usually work with various unstructured information sources for recommendation, such as textual reviews, visual images, and various implicit or explicit feedbacks. Though structured knowledge bases were considered in content-based approaches, they have been largely neglected recently due to the availability of vast amount of data, and the learning power of many complex models. However, structured knowledge bases exhibit unique advantages in personalized recommendation systems. When the explicit knowledge about users and items is considered for recommendation, the system could provide highly customized recommendations based on users' historical behaviors. A great challenge for using knowledge bases for recommendation is how to integrated large-scale structured and unstructured data, while taking advantage of collaborative filtering for highly accurate performance. Recent achievements on knowledge base embedding sheds light on this problem, which makes it possible to learn user and item representations while preserving the structure of their relationship with external knowledge. In this work, we propose to reason over knowledge base embeddings for personalized recommendation. Specifically, we propose a knowledge base representation learning approach to embed heterogeneous entities for recommendation. Experimental results on real-world dataset verified the superior performance of our approach compared with state-of-the-art baselines.

Recommender systems play a crucial role in mitigating the problem of information overload by suggesting users' personalized items or services. The vast majority of traditional recommender systems consider the recommendation procedure as a static process and make recommendations following a fixed strategy. In this paper, we propose a novel recommender system with the capability of continuously improving its strategies during the interactions with users. We model the sequential interactions between users and a recommender system as a Markov Decision Process (MDP) and leverage Reinforcement Learning (RL) to automatically learn the optimal strategies via recommending trial-and-error items and receiving reinforcements of these items from users' feedbacks. In particular, we introduce an online user-agent interacting environment simulator, which can pre-train and evaluate model parameters offline before applying the model online. Moreover, we validate the importance of list-wise recommendations during the interactions between users and agent, and develop a novel approach to incorporate them into the proposed framework LIRD for list-wide recommendations. The experimental results based on a real-world e-commerce dataset demonstrate the effectiveness of the proposed framework.

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