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Simulated patient systems play a crucial role in modern medical education and research, providing safe, integrative learning environments and enabling clinical decision-making simulations. Large Language Models (LLM) could advance simulated patient systems by replicating medical conditions and patient-doctor interactions with high fidelity and low cost. However, ensuring the effectiveness and trustworthiness of these systems remains a challenge, as they require a large, diverse, and precise patient knowledgebase, along with a robust and stable knowledge diffusion to users. Here, we developed AIPatient, an advanced simulated patient system with AIPatient Knowledge Graph (AIPatient KG) as the input and the Reasoning Retrieval-Augmented Generation (Reasoning RAG) agentic workflow as the generation backbone. AIPatient KG samples data from Electronic Health Records (EHRs) in the Medical Information Mart for Intensive Care (MIMIC)-III database, producing a clinically diverse and relevant cohort of 1,495 patients with high knowledgebase validity (F1 0.89). Reasoning RAG leverages six LLM powered agents spanning tasks including retrieval, KG query generation, abstraction, checker, rewrite, and summarization. This agentic framework reaches an overall accuracy of 94.15% in EHR-based medical Question Answering (QA), outperforming benchmarks that use either no agent or only partial agent integration. Our system also presents high readability (median Flesch Reading Ease 77.23; median Flesch Kincaid Grade 5.6), robustness (ANOVA F-value 0.6126, p<0.1), and stability (ANOVA F-value 0.782, p<0.1). The promising performance of the AIPatient system highlights its potential to support a wide range of applications, including medical education, model evaluation, and system integration.

The successful deployment of deep learning-based techniques for autonomous systems is highly dependent on the data availability for the respective system in its deployment environment. Especially for unstructured outdoor environments, very few datasets exist for even fewer robotic platforms and scenarios. In an earlier work, we presented the German Outdoor and Offroad Dataset (GOOSE) framework along with 10000 multimodal frames from an offroad vehicle to enhance the perception capabilities in unstructured environments. In this work, we address the generalizability of the GOOSE framework. To accomplish this, we open-source the GOOSE-Ex dataset, which contains additional 5000 labeled multimodal frames from various completely different environments, recorded on a robotic excavator and a quadruped platform. We perform a comprehensive analysis of the semantic segmentation performance on different platforms and sensor modalities in unseen environments. In addition, we demonstrate how the combined datasets can be utilized for different downstream applications or competitions such as offroad navigation, object manipulation or scene completion. The dataset, its platform documentation and pre-trained state-of-the-art models for offroad perception will be made available on //goose-dataset.de/. \

Context: In software development organizations employing weak or collective ownership, different teams are allowed and expected to autonomously perform changes in various components. This creates diversity both in the knowledge of, and in the responsibility for, individual components. Objective: Our objective is to understand how and why different teams introduce technical debt in the form of code clones as they change different components. Method: We collected data about change size and clone introductions made by ten teams in eight components which was part of a large industrial software system. We then designed a Multi-Level Generalized Linear Model (MLGLM), to illustrate the teams' differing behavior. Finally, we discussed the results with three development teams, plus line manager and the architect team, evaluating whether the model inferences aligned with what they expected. Responses were recorded and thematically coded. Results: The results show that teams do behave differently in different components, and the feedback from the teams indicates that this method of illustrating team behavior can be useful as a complement to traditional summary statistics of ownership. Conclusions: We find that our model-based approach produces useful visualizations of team introductions of code clones as they change different components. Practitioners stated that the visualizations gave them insights that were useful, and by comparing with an average team, inter-team comparisons can be avoided. Thus, this has the potential to be a useful feedback tool for teams in software development organizations that employ weak or collective ownership.

We present a novel autonomous driving framework, DualAD, designed to imitate human reasoning during driving. DualAD comprises two layers: a rule-based motion planner at the bottom layer that handles routine driving tasks requiring minimal reasoning, and an upper layer featuring a rule-based text encoder that converts driving scenarios from absolute states into text description. This text is then processed by a large language model (LLM) to make driving decisions. The upper layer intervenes in the bottom layer's decisions when potential danger is detected, mimicking human reasoning in critical situations. Closed-loop experiments demonstrate that DualAD, using a zero-shot pre-trained model, significantly outperforms rule-based motion planners that lack reasoning abilities. Our experiments also highlight the effectiveness of the text encoder, which considerably enhances the model's scenario understanding. Additionally, the integrated DualAD model improves with stronger LLMs, indicating the framework's potential for further enhancement. We make code and benchmarks publicly available.

Analyzing sequences of interactions between users and items, sequential recommendation models can learn user intent and make predictions about the next item. Next to item interactions, most systems also have interactions with what we call non-item pages: these pages are not related to specific items but still can provide insights of the user's interests, as, for example, navigation pages. We therefore propose a general way to include these non-item pages in sequential recommendation models to enhance next-item prediction. First, we demonstrate the influence of non-item pages on following interactions with the hypotheses testing framework HypTrails and propose methods for representing non-item pages in sequential recommendation models. Subsequently, we adapt popular sequential recommender models to integrate non-item pages and investigate their performance with different item representation strategies as well as their ability to handle noisy data. To show the general capabilities of the models to integrate non-item pages, we create a synthetic dataset for a controlled setting and then evaluate the improvements from including non-item pages on two real-world datasets. Our results show that non-item pages are a valuable source of information, and incorporating them in sequential recommendation models increases the performance of next-item prediction across all analyzed model architectures.

Recent advances of data-driven machine learning have revolutionized fields like computer vision, reinforcement learning, and many scientific and engineering domains. In many real-world and scientific problems, systems that generate data are governed by physical laws. Recent work shows that it provides potential benefits for machine learning models by incorporating the physical prior and collected data, which makes the intersection of machine learning and physics become a prevailing paradigm. In this survey, we present this learning paradigm called Physics-Informed Machine Learning (PIML) which is to build a model that leverages empirical data and available physical prior knowledge to improve performance on a set of tasks that involve a physical mechanism. We systematically review the recent development of physics-informed machine learning from three perspectives of machine learning tasks, representation of physical prior, and methods for incorporating physical prior. We also propose several important open research problems based on the current trends in the field. We argue that encoding different forms of physical prior into model architectures, optimizers, inference algorithms, and significant domain-specific applications like inverse engineering design and robotic control is far from fully being explored in the field of physics-informed machine learning. We believe that this study will encourage researchers in the machine learning community to actively participate in the interdisciplinary research of physics-informed machine learning.

Existing recommender systems extract the user preference based on learning the correlation in data, such as behavioral correlation in collaborative filtering, feature-feature, or feature-behavior correlation in click-through rate prediction. However, regretfully, the real world is driven by causality rather than correlation, and correlation does not imply causation. For example, the recommender systems can recommend a battery charger to a user after buying a phone, in which the latter can serve as the cause of the former, and such a causal relation cannot be reversed. Recently, to address it, researchers in recommender systems have begun to utilize causal inference to extract causality, enhancing the recommender system. In this survey, we comprehensively review the literature on causal inference-based recommendation. At first, we present the fundamental concepts of both recommendation and causal inference as the basis of later content. We raise the typical issues that the non-causality recommendation is faced. Afterward, we comprehensively review the existing work of causal inference-based recommendation, based on a taxonomy of what kind of problem causal inference addresses. Last, we discuss the open problems in this important research area, along with interesting future works.

Autonomic computing investigates how systems can achieve (user) specified control outcomes on their own, without the intervention of a human operator. Autonomic computing fundamentals have been substantially influenced by those of control theory for closed and open-loop systems. In practice, complex systems may exhibit a number of concurrent and inter-dependent control loops. Despite research into autonomic models for managing computer resources, ranging from individual resources (e.g., web servers) to a resource ensemble (e.g., multiple resources within a data center), research into integrating Artificial Intelligence (AI) and Machine Learning (ML) to improve resource autonomy and performance at scale continues to be a fundamental challenge. The integration of AI/ML to achieve such autonomic and self-management of systems can be achieved at different levels of granularity, from full to human-in-the-loop automation. In this article, leading academics, researchers, practitioners, engineers, and scientists in the fields of cloud computing, AI/ML, and quantum computing join to discuss current research and potential future directions for these fields. Further, we discuss challenges and opportunities for leveraging AI and ML in next generation computing for emerging computing paradigms, including cloud, fog, edge, serverless and quantum computing environments.

Recommender systems exploit interaction history to estimate user preference, having been heavily used in a wide range of industry applications. However, static recommendation models are difficult to answer two important questions well due to inherent shortcomings: (a) What exactly does a user like? (b) Why does a user like an item? The shortcomings are due to the way that static models learn user preference, i.e., without explicit instructions and active feedback from users. The recent rise of conversational recommender systems (CRSs) changes this situation fundamentally. In a CRS, users and the system can dynamically communicate through natural language interactions, which provide unprecedented opportunities to explicitly obtain the exact preference of users. Considerable efforts, spread across disparate settings and applications, have been put into developing CRSs. Existing models, technologies, and evaluation methods for CRSs are far from mature. In this paper, we provide a systematic review of the techniques used in current CRSs. We summarize the key challenges of developing CRSs into five directions: (1) Question-based user preference elicitation. (2) Multi-turn conversational recommendation strategies. (3) Dialogue understanding and generation. (4) Exploitation-exploration trade-offs. (5) Evaluation and user simulation. These research directions involve multiple research fields like information retrieval (IR), natural language processing (NLP), and human-computer interaction (HCI). Based on these research directions, we discuss some future challenges and opportunities. We provide a road map for researchers from multiple communities to get started in this area. We hope this survey helps to identify and address challenges in CRSs and inspire future research.

Since hardware resources are limited, the objective of training deep learning models is typically to maximize accuracy subject to the time and memory constraints of training and inference. We study the impact of model size in this setting, focusing on Transformer models for NLP tasks that are limited by compute: self-supervised pretraining and high-resource machine translation. We first show that even though smaller Transformer models execute faster per iteration, wider and deeper models converge in significantly fewer steps. Moreover, this acceleration in convergence typically outpaces the additional computational overhead of using larger models. Therefore, the most compute-efficient training strategy is to counterintuitively train extremely large models but stop after a small number of iterations. This leads to an apparent trade-off between the training efficiency of large Transformer models and the inference efficiency of small Transformer models. However, we show that large models are more robust to compression techniques such as quantization and pruning than small models. Consequently, one can get the best of both worlds: heavily compressed, large models achieve higher accuracy than lightly compressed, small models.