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With increasing revelations of academic fraud, detecting forged experimental images in the biomedical field has become a public concern. The challenge lies in the fact that copy-move targets can include background tissue, small foreground objects, or both, which may be out of the training domain and subject to unseen attacks, rendering standard object-detection-based approaches less effective. To address this, we reformulate the problem of detecting biomedical copy-move forgery regions as an intra-image co-saliency detection task and propose CMSeg-Net, a copy-move forgery segmentation network capable of identifying unseen duplicated areas. Built on a multi-resolution encoder-decoder architecture, CMSeg-Net incorporates self-correlation and correlation-assisted spatial-attention modules to detect intra-image regional similarities within feature tensors at each observation scale. This design helps distinguish even small copy-move targets in complex microscopic images from other similar objects. Furthermore, we created a copy-move forgery dataset of optical microscopic images, named FakeParaEgg, using open data from the ICIP 2022 Challenge to support CMSeg-Net's development and verify its performance. Extensive experiments demonstrate that our approach outperforms previous state-of-the-art methods on the FakeParaEgg dataset and other open copy-move detection datasets, including CASIA-CMFD, CoMoFoD, and CMF. The FakeParaEgg dataset, our source code, and the CMF dataset with our manually defined segmentation ground truths available at ``//github.com/YoursEver/FakeParaEgg''.

This exhaustive investigation is dedicated to delving into the intricate legal aspects that underlie the inefficiency in the advancement and utilization of sustainable energies, with a primary focus on the dynamic landscape of China and carefully selected representative nations. In an era where the global community increasingly acknowledges the pressing need for environmentally-friendly alternatives to traditional fossil fuels, renewable energy sources have rightfully garnered substantial attention as encouraging solutions. Nevertheless, notwithstanding their potential to revolutionize the energy sector and counteract climate change, a multitude of legal and regulatory barriers may present formidable hindrances that impede their seamless integration into the energy landscape. With a resolute and concentrated aim, the research sets forth on a painstaking exploration and analysis of the intricate legal frameworks, policies, and institutional arrangements in place within China and the chosen representative nations. The ultimate objective is to discern and identify potential challenges and inefficiencies that could hinder the progress of renewable energy projects and initiatives.

As learning-based methods for legged robots rapidly grow in popularity, it is important that we can provide safety assurances efficiently across different controllers and environments. Existing works either rely on a priori knowledge of the environment and safety constraints to ensure system safety or provide assurances for a specific locomotion policy. To address these limitations, we propose an observation-conditioned reachability-based (OCR) safety-filter framework. Our key idea is to use an OCR value network (OCR-VN) that predicts the optimal control-theoretic safety value function for new failure regions and dynamic uncertainty during deployment time. Specifically, the OCR-VN facilitates rapid safety adaptation through two key components: a LiDAR-based input that allows the dynamic construction of safe regions in light of new obstacles and a disturbance estimation module that accounts for dynamics uncertainty in the wild. The predicted safety value function is used to construct an adaptive safety filter that overrides the nominal quadruped controller when necessary to maintain safety. Through simulation studies and hardware experiments on a Unitree Go1 quadruped, we demonstrate that the proposed framework can automatically safeguard a wide range of hierarchical quadruped controllers, adapts to novel environments, and is robust to unmodeled dynamics without a priori access to the controllers or environments - hence, "One Filter to Deploy Them All". The experiment videos can be found on the project website.

Clinical trials are an indispensable part of the drug development process, bridging the gap between basic research and clinical application. During the development of new drugs, clinical trials are used not only to evaluate the safety and efficacy of the drug but also to explore its dosage, treatment regimens, and potential side effects. This review discusses the various stages of clinical trials, including Phase I (safety assessment), Phase II (preliminary efficacy evaluation), Phase III (large-scale validation), and Phase IV (post-marketing surveillance), highlighting the characteristics of each phase and their interrelationships. Additionally, the paper addresses the major challenges encountered in clinical trials, such as ethical issues, subject recruitment difficulties, diversity and representativeness concerns, and proposes strategies for overcoming these challenges. With the advancement of technology, innovative technologies such as artificial intelligence, big data, and digitalization are gradually transforming clinical trial design and implementation, improving trial efficiency and data quality. The article also looks forward to the future of clinical trials, particularly the impact of emerging therapies such as gene therapy and immunotherapy on trial design, as well as the importance of regulatory reforms and global collaboration. In conclusion, the core role of clinical trials in drug development will continue to drive the progress of innovative drug development and clinical treatment.

The widespread adoption of quadrotors for diverse applications, from agriculture to public safety, necessitates an understanding of the aerodynamic disturbances they create. This paper introduces a computationally lightweight model for estimating the time-averaged magnitude of the induced flow below quadrotors in hover. Unlike related approaches that rely on expensive computational fluid dynamics (CFD) simulations or drone specific time-consuming empirical measurements, our method leverages classical theory from turbulent flows. By analyzing over 16 hours of flight data from drones of varying sizes within a large motion capture system, we show for the first time that the combined flow from all drone propellers is well-approximated by a turbulent jet after 2.5 drone-diameters below the vehicle. Using a novel normalization and scaling, we experimentally identify model parameters that describe a unified mean velocity field below differently sized quadrotors. The model, which requires only the drone's mass, propeller size, and drone size for calculations, accurately describes the far-field airflow over a long-range in a very large volume which is impractical to simulate using CFD. Our model offers a practical tool for ensuring safer operations near humans, optimizing sensor placements and drone control in multi-agent scenarios. We demonstrate the latter by designing a controller that compensates for the downwash of another drone, leading to a four times lower altitude deviation when passing below.

In the burgeoning field of medical imaging, precise computation of 3D volume holds a significant importance for subsequent qualitative analysis of 3D reconstructed objects. Combining multivariate calculus, marching cube algorithm, and binary indexed tree data structure, we developed an algorithm for efficient computation of intrinsic volume of any volumetric data recovered from computed tomography (CT) or magnetic resonance (MR). We proposed the 30 configurations of volume values based on the polygonal mesh generation method. Our algorithm processes the data in scan-line order simultaneously with reconstruction algorithm to create a Fenwick tree, ensuring query time much faster and assisting users' edition of slicing or transforming model. We tested the algorithm's accuracy on simple 3D objects (e.g., sphere, cylinder) to complicated structures (e.g., lungs, cardiac chambers). The result deviated within $\pm 0.004 \text{cm}^3$ and there is still room for further improvement.

Autonomous systems are soon to be ubiquitous, from manufacturing autonomy to agricultural field robots, and from health care assistants to the entertainment industry. The majority of these systems are developed with modular sub-components for decision-making, planning, and control that may be hand-engineered or learning-based. While these existing approaches have been shown to perform well under the situations they were specifically designed for, they can perform especially poorly in rare, out-of-distribution scenarios that will undoubtedly arise at test-time. The rise of foundation models trained on multiple tasks with impressively large datasets from a variety of fields has led researchers to believe that these models may provide common sense reasoning that existing planners are missing. Researchers posit that this common sense reasoning will bridge the gap between algorithm development and deployment to out-of-distribution tasks, like how humans adapt to unexpected scenarios. Large language models have already penetrated the robotics and autonomous systems domains as researchers are scrambling to showcase their potential use cases in deployment. While this application direction is very promising empirically, foundation models are known to hallucinate and generate decisions that may sound reasonable, but are in fact poor. We argue there is a need to step back and simultaneously design systems that can quantify the certainty of a model's decision, and detect when it may be hallucinating. In this work, we discuss the current use cases of foundation models for decision-making tasks, provide a general definition for hallucinations with examples, discuss existing approaches to hallucination detection and mitigation with a focus on decision problems, and explore areas for further research in this exciting field.

In pace with developments in the research field of artificial intelligence, knowledge graphs (KGs) have attracted a surge of interest from both academia and industry. As a representation of semantic relations between entities, KGs have proven to be particularly relevant for natural language processing (NLP), experiencing a rapid spread and wide adoption within recent years. Given the increasing amount of research work in this area, several KG-related approaches have been surveyed in the NLP research community. However, a comprehensive study that categorizes established topics and reviews the maturity of individual research streams remains absent to this day. Contributing to closing this gap, we systematically analyzed 507 papers from the literature on KGs in NLP. Our survey encompasses a multifaceted review of tasks, research types, and contributions. As a result, we present a structured overview of the research landscape, provide a taxonomy of tasks, summarize our findings, and highlight directions for future work.

Deep generative modelling is a class of techniques that train deep neural networks to model the distribution of training samples. Research has fragmented into various interconnected approaches, each of which making trade-offs including run-time, diversity, and architectural restrictions. In particular, this compendium covers energy-based models, variational autoencoders, generative adversarial networks, autoregressive models, normalizing flows, in addition to numerous hybrid approaches. These techniques are drawn under a single cohesive framework, comparing and contrasting to explain the premises behind each, while reviewing current state-of-the-art advances and implementations.

We propose a novel attention gate (AG) model for medical imaging that automatically learns to focus on target structures of varying shapes and sizes. Models trained with AGs implicitly learn to suppress irrelevant regions in an input image while highlighting salient features useful for a specific task. This enables us to eliminate the necessity of using explicit external tissue/organ localisation modules of cascaded convolutional neural networks (CNNs). AGs can be easily integrated into standard CNN architectures such as the U-Net model with minimal computational overhead while increasing the model sensitivity and prediction accuracy. The proposed Attention U-Net architecture is evaluated on two large CT abdominal datasets for multi-class image segmentation. Experimental results show that AGs consistently improve the prediction performance of U-Net across different datasets and training sizes while preserving computational efficiency. The code for the proposed architecture is publicly available.