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Magnetic resonance imaging (MRI) always suffered from the problem of long acquisition time. MRI reconstruction is one solution to reduce scan time by skipping certain phase-encoding lines and then restoring high-quality images from undersampled measurements. Recently, implicit neural representation (INR) has emerged as a new deep learning method that represents an object as a continuous function of spatial coordinates, and this function is normally parameterized by a multilayer perceptron (MLP). In this paper, we propose a novel MRI parallel reconstruction method based on INR, which represents the fully-sampled images as the function of voxel coordinates and prior feature vectors of undersampled images for overcoming the generalization problem of INR. Specifically, we introduce a scale-embedded encoder to produce scale-independent voxel-specific features from MR images with different undersampled scales and then concatenate with coordinates vectors to recover fully-sampled MR images via an MLP, thus achieving arbitrary scale reconstruction. The performance of the proposed method was assessed by experimenting on publicly available MRI datasets and compared with other reconstruction methods. Our quantitative evaluation demonstrates the superiority of the proposed method over alternative reconstruction methods.

Anomaly Detection (AD) is a critical task that involves identifying observations that do not conform to a learned model of normality. Prior work in deep AD is predominantly based on a familiarity hypothesis, where familiar features serve as the reference in a pre-trained embedding space. While this strategy has proven highly successful, it turns out that it causes consistent false negatives when anomalies consist of truly novel features that are not well captured by the pre-trained encoding. We propose a novel approach to AD using explainability to capture novel features as unexplained observations in the input space. We achieve strong performance across a wide range of anomaly benchmarks by combining similarity and novelty in a hybrid approach. Our approach establishes a new state-of-the-art across multiple benchmarks, handling diverse anomaly types while eliminating the need for expensive background models and dense matching. In particular, we show that by taking account of novel features, we reduce false negative anomalies by up to 40% on challenging benchmarks compared to the state-of-the-art. Our method gives visually inspectable explanations for pixel-level anomalies.

In Reinforcement Learning (RL), agents aim at maximizing cumulative rewards in a given environment. During the learning process, RL agents face the dilemma of exploitation and exploration: leveraging existing knowledge to acquire rewards or seeking potentially higher ones. Using uncertainty as a guiding principle provides an active and effective approach to solving this dilemma and ensemble-based methods are one of the prominent avenues for quantifying uncertainty. Nevertheless, conventional ensemble-based uncertainty estimation lacks an explicit prior, deviating from Bayesian principles. Besides, this method requires diversity among members to generate less biased uncertainty estimation results. To address the above problems, previous research has incorporated random functions as priors. Building upon these foundational efforts, our work introduces an innovative approach with delicately designed prior NNs, which can incorporate maximal diversity in the initial value functions of RL. Our method has demonstrated superior performance compared with the random prior approaches in solving classic control problems and general exploration tasks, significantly improving sample efficiency.

Fourier feature approximations have been successfully applied in the literature for scalable Gaussian Process (GP) regression. In particular, Quadrature Fourier Features (QFF) derived from Gaussian quadrature rules have gained popularity in recent years due to their improved approximation accuracy and better calibrated uncertainty estimates compared to Random Fourier Feature (RFF) methods. However, a key limitation of QFF is that its performance can suffer from well-known pathologies related to highly oscillatory quadrature, resulting in mediocre approximation with limited features. We address this critical issue via a new Trigonometric Quadrature Fourier Feature (TQFF) method, which uses a novel non-Gaussian quadrature rule specifically tailored for the desired Fourier transform. We derive an exact quadrature rule for TQFF, along with kernel approximation error bounds for the resulting feature map. We then demonstrate the improved performance of our method over RFF and Gaussian QFF in a suite of numerical experiments and applications, and show the TQFF enjoys accurate GP approximations over a broad range of length-scales using fewer features.

The graphical structure of Probabilistic Graphical Models (PGMs) represents the conditional independence (CI) relations that hold in the modeled distribution. Every separator in the graph represents a conditional independence relation in the distribution, making them the vehicle through which new conditional independencies are inferred and verified. The notion of separation in graphs depends on whether the graph is directed (i.e., a Bayesian Network), or undirected (i.e., a Markov Network). The premise of all current systems-of-inference for deriving CIs in PGMs, is that the set of CIs used for the construction of the PGM hold exactly. In practice, algorithms for extracting the structure of PGMs from data discover approximate CIs that do not hold exactly in the distribution. In this paper, we ask how the error in this set propagates to the inferred CIs read off the graphical structure. More precisely, what guarantee can we provide on the inferred CI when the set of CIs that entailed it hold only approximately? It has recently been shown that in the general case, no such guarantee can be provided. In this work, we prove new negative and positive results concerning this problem. We prove that separators in undirected PGMs do not necessarily represent approximate CIs. That is, no guarantee can be provided for CIs inferred from the structure of undirected graphs. We prove that such a guarantee exists for the set of CIs inferred in directed graphical models, making the $d$-separation algorithm a sound and complete system for inferring approximate CIs. We also establish improved approximation guarantees for independence relations derived from marginal and saturated CIs.

To promote the generalization ability of breast tumor segmentation models, as well as to improve the segmentation performance for breast tumors with smaller size, low-contrast amd irregular shape, we propose a progressive dual priori network (PDPNet) to segment breast tumors from dynamic enhanced magnetic resonance images (DCE-MRI) acquired at different sites. The PDPNet first cropped tumor regions with a coarse-segmentation based localization module, then the breast tumor mask was progressively refined by using the weak semantic priori and cross-scale correlation prior knowledge. To validate the effectiveness of PDPNet, we compared it with several state-of-the-art methods on multi-center datasets. The results showed that, comparing against the suboptimal method, the DSC, SEN, KAPPA and HD95 of PDPNet were improved 3.63\%, 8.19\%, 5.52\%, and 3.66\% respectively. In addition, through ablations, we demonstrated that the proposed localization module can decrease the influence of normal tissues and therefore improve the generalization ability of the model. The weak semantic priors allow focusing on tumor regions to avoid missing small tumors and low-contrast tumors. The cross-scale correlation priors are beneficial for promoting the shape-aware ability for irregual tumors. Thus integrating them in a unified framework improved the multi-center breast tumor segmentation performance.

Recent contrastive representation learning methods rely on estimating mutual information (MI) between multiple views of an underlying context. E.g., we can derive multiple views of a given image by applying data augmentation, or we can split a sequence into views comprising the past and future of some step in the sequence. Contrastive lower bounds on MI are easy to optimize, but have a strong underestimation bias when estimating large amounts of MI. We propose decomposing the full MI estimation problem into a sum of smaller estimation problems by splitting one of the views into progressively more informed subviews and by applying the chain rule on MI between the decomposed views. This expression contains a sum of unconditional and conditional MI terms, each measuring modest chunks of the total MI, which facilitates approximation via contrastive bounds. To maximize the sum, we formulate a contrastive lower bound on the conditional MI which can be approximated efficiently. We refer to our general approach as Decomposed Estimation of Mutual Information (DEMI). We show that DEMI can capture a larger amount of MI than standard non-decomposed contrastive bounds in a synthetic setting, and learns better representations in a vision domain and for dialogue generation.

Recently, a considerable literature has grown up around the theme of Graph Convolutional Network (GCN). How to effectively leverage the rich structural information in complex graphs, such as knowledge graphs with heterogeneous types of entities and relations, is a primary open challenge in the field. Most GCN methods are either restricted to graphs with a homogeneous type of edges (e.g., citation links only), or focusing on representation learning for nodes only instead of jointly propagating and updating the embeddings of both nodes and edges for target-driven objectives. This paper addresses these limitations by proposing a novel framework, namely the Knowledge Embedding based Graph Convolutional Network (KE-GCN), which combines the power of GCNs in graph-based belief propagation and the strengths of advanced knowledge embedding (a.k.a. knowledge graph embedding) methods, and goes beyond. Our theoretical analysis shows that KE-GCN offers an elegant unification of several well-known GCN methods as specific cases, with a new perspective of graph convolution. Experimental results on benchmark datasets show the advantageous performance of KE-GCN over strong baseline methods in the tasks of knowledge graph alignment and entity classification.

Multi-relation Question Answering is a challenging task, due to the requirement of elaborated analysis on questions and reasoning over multiple fact triples in knowledge base. In this paper, we present a novel model called Interpretable Reasoning Network that employs an interpretable, hop-by-hop reasoning process for question answering. The model dynamically decides which part of an input question should be analyzed at each hop; predicts a relation that corresponds to the current parsed results; utilizes the predicted relation to update the question representation and the state of the reasoning process; and then drives the next-hop reasoning. Experiments show that our model yields state-of-the-art results on two datasets. More interestingly, the model can offer traceable and observable intermediate predictions for reasoning analysis and failure diagnosis, thereby allowing manual manipulation in predicting the final answer.