Recent advancements in large language models (LLMs) have led to the development of highly potent models like OpenAI's ChatGPT. These models have exhibited exceptional performance in a variety of tasks, such as question answering, essay composition, and code generation. However, their effectiveness in the healthcare sector remains uncertain. In this study, we seek to investigate the potential of ChatGPT to aid in clinical text mining by examining its ability to extract structured information from unstructured healthcare texts, with a focus on biological named entity recognition and relation extraction. However, our preliminary results indicate that employing ChatGPT directly for these tasks resulted in poor performance and raised privacy concerns associated with uploading patients' information to the ChatGPT API. To overcome these limitations, we propose a new training paradigm that involves generating a vast quantity of high-quality synthetic data with labels utilizing ChatGPT and fine-tuning a local model for the downstream task. Our method has resulted in significant improvements in the performance of downstream tasks, improving the F1-score from 23.37% to 63.99% for the named entity recognition task and from 75.86% to 83.59% for the relation extraction task. Furthermore, generating data using ChatGPT can significantly reduce the time and effort required for data collection and labeling, as well as mitigate data privacy concerns. In summary, the proposed framework presents a promising solution to enhance the applicability of LLM models to clinical text mining.
Objective: To assess the performance of the OpenAI GPT API in accurately and efficiently identifying relevant titles and abstracts from real-world clinical review datasets and compare its performance against ground truth labelling by two independent human reviewers. Methods: We introduce a novel workflow using the OpenAI GPT API for screening titles and abstracts in clinical reviews. A Python script was created to make calls to the GPT API with the screening criteria in natural language and a corpus of title and abstract datasets that have been filtered by a minimum of two human reviewers. We compared the performance of our model against human-reviewed papers across six review papers, screening over 24,000 titles and abstracts. Results: Our results show an accuracy of 0.91, a sensitivity of excluded papers of 0.91, and a sensitivity of included papers of 0.76. On a randomly selected subset of papers, the GPT API demonstrated the ability to provide reasoning for its decisions and corrected its initial decision upon being asked to explain its reasoning for a subset of incorrect classifications. Conclusion: The GPT API has the potential to streamline the clinical review process, save valuable time and effort for researchers, and contribute to the overall quality of clinical reviews. By prioritizing the workflow and acting as an aid rather than a replacement for researchers and reviewers, the GPT API can enhance efficiency and lead to more accurate and reliable conclusions in medical research.
As foundation models continue to exponentially scale in size, efficient methods of adaptation become increasingly critical. Parameter-efficient fine-tuning (PEFT), a recent class of techniques that require only modifying a small percentage of the model parameters, is currently the most popular method for adapting large language models (LLMs). Several PEFT techniques have recently been proposed with varying tradeoffs. We provide a comprehensive and uniform benchmark of various PEFT techniques across a representative LLM, the FLAN-T5 model, and evaluate model performance across different data scales of classification and generation datasets. Based on this, we provide a framework for choosing the optimal fine-tuning techniques given the task type and data availability. Contrary to popular belief, we also empirically prove that PEFT techniques converge slower than full tuning in low data scenarios, and posit the amount of data required for PEFT methods to both perform well and converge efficiently. Lastly, we further optimize these PEFT techniques by selectively choosing which parts of the model to train, and find that these techniques can be applied with significantly fewer parameters while maintaining and even improving performance.
Recent advancements in the field of natural language generation have facilitated the use of large language models to assess the quality of generated text. Although these models have shown promising results in tasks such as machine translation and summarization, their applicability in code generation tasks remains limited without human involvement. The complexity of programming concepts required for such tasks makes it difficult to develop evaluation metrics that align with human judgment. Token-matching-based metrics, such as BLEU, have demonstrated weak correlations with human practitioners in code generation tasks. Moreover, the utilization of human-written test suites to evaluate functional correctness can be challenging in domains with low resources. To overcome these obstacles, we propose a new evaluation framework based on the GPT-3.5 (\texttt{GPT-3.5-turbo}), for code generation assessments. Our framework addresses the limitations of existing approaches by achieving superior correlations with functional correctness and human preferences, without the need for test oracles or references. We evaluate the efficacy of our framework on two different tasks and four programming languages, comparing its performance with the state-of-the-art CodeBERTScore metric, which relies on a pre-trained model. Our results demonstrate that our framework surpasses CodeBERTScore, delivering high levels of accuracy and consistency across various programming languages and tasks. We also make our evaluation framework and datasets available to the public at \url{//github.com/terryyz/llm-code-eval}, encouraging further research in the evaluation of code generation.
Large language models generate fluent texts and can follow natural language instructions to solve a wide range of tasks without task-specific training. Nevertheless, it is notoriously difficult to control their generation to satisfy the various constraints required by different applications. In this work, we present InstructCTG, a controlled text generation framework that incorporates different constraints by conditioning on natural language descriptions and demonstrations of the constraints. In particular, we first extract the underlying constraints of natural texts through a combination of off-the-shelf NLP tools and simple heuristics. We then verbalize the constraints into natural language instructions to form weakly supervised training data. By prepending natural language descriptions of the constraints and a few demonstrations, we fine-tune a pre-trained language model to incorporate various types of constraints. Compared to existing search-based or score-based methods, InstructCTG is more flexible to different constraint types and has a much smaller impact on the generation quality and speed because it does not modify the decoding procedure. Additionally, InstructCTG allows the model to adapt to new constraints without re-training through the use of few-shot task generalization and in-context learning abilities of instruction-tuned language models.
Large multimodal datasets have been instrumental in recent breakthroughs such as CLIP, Stable Diffusion, and GPT-4. At the same time, datasets rarely receive the same research attention as model architectures or training algorithms. To address this shortcoming in the machine learning ecosystem, we introduce DataComp, a benchmark where the training code is fixed and researchers innovate by proposing new training sets. We provide a testbed for dataset experiments centered around a new candidate pool of 12.8B image-text pairs from Common Crawl. Participants in our benchmark design new filtering techniques or curate new data sources and then evaluate their new dataset by running our standardized CLIP training code and testing on 38 downstream test sets. Our benchmark consists of multiple scales, with four candidate pool sizes and associated compute budgets ranging from 12.8M to 12.8B samples seen during training. This multi-scale design facilitates the study of scaling trends and makes the benchmark accessible to researchers with varying resources. Our baseline experiments show that the DataComp workflow is a promising way of improving multimodal datasets. We introduce DataComp-1B, a dataset created by applying a simple filtering algorithm to the 12.8B candidate pool. The resulting 1.4B subset enables training a CLIP ViT-L/14 from scratch to 79.2% zero-shot accuracy on ImageNet. Our new ViT-L/14 model outperforms a larger ViT-g/14 trained on LAION-2B by 0.7 percentage points while requiring 9x less training compute. We also outperform OpenAI's CLIP ViT-L/14 by 3.7 percentage points, which is trained with the same compute budget as our model. These gains highlight the potential for improving model performance by carefully curating training sets. We view DataComp-1B as only the first step and hope that DataComp paves the way toward the next generation of multimodal datasets.
Zero-resource cross-lingual transfer approaches aim to apply supervised models from a source language to unlabelled target languages. In this paper we perform an in-depth study of the two main techniques employed so far for cross-lingual zero-resource sequence labelling, based either on data or model transfer. Although previous research has proposed translation and annotation projection (data-based cross-lingual transfer) as an effective technique for cross-lingual sequence labelling, in this paper we experimentally demonstrate that high capacity multilingual language models applied in a zero-shot (model-based cross-lingual transfer) setting consistently outperform data-based cross-lingual transfer approaches. A detailed analysis of our results suggests that this might be due to important differences in language use. More specifically, machine translation often generates a textual signal which is different to what the models are exposed to when using gold standard data, which affects both the fine-tuning and evaluation processes. Our results also indicate that data-based cross-lingual transfer approaches remain a competitive option when high-capacity multilingual language models are not available.
The extraordinary performance of large language models (LLMs) heightens the importance of detecting whether the context is generated by an AI system. More importantly, while more and more companies and institutions release their LLMs, the origin can be hard to trace. Since LLMs are heading towards the time of AGI, similar to the origin tracing in anthropology, it is of great importance to trace the origin of LLMs. In this paper, we first raise the concern of the origin tracing of LLMs and propose an effective method to trace and detect AI-generated contexts. We introduce a novel algorithm that leverages the contrastive features between LLMs and extracts model-wise features to trace the text origins. Our proposed method works under both white-box and black-box settings therefore can be widely generalized to detect various LLMs.(e.g. can be generalized to detect GPT-3 models without the GPT-3 models). Also, our proposed method requires only limited data compared with the supervised learning methods and can be extended to trace new-coming model origins. We construct extensive experiments to examine whether we can trace the origins of given texts. We provide valuable observations based on the experimental results, such as the difficulty level of AI origin tracing, and the AI origin similarities, and call for ethical concerns of LLM providers. We are releasing all codes and data as a toolkit and benchmark for future AI origin tracing and detecting studies. \footnote{We are releasing all available resource at \url{//github.com/OpenLMLab/}.}
Graphs are important data representations for describing objects and their relationships, which appear in a wide diversity of real-world scenarios. As one of a critical problem in this area, graph generation considers learning the distributions of given graphs and generating more novel graphs. Owing to their wide range of applications, generative models for graphs, which have a rich history, however, are traditionally hand-crafted and only capable of modeling a few statistical properties of graphs. Recent advances in deep generative models for graph generation is an important step towards improving the fidelity of generated graphs and paves the way for new kinds of applications. This article provides an extensive overview of the literature in the field of deep generative models for graph generation. Firstly, the formal definition of deep generative models for the graph generation and the preliminary knowledge are provided. Secondly, taxonomies of deep generative models for both unconditional and conditional graph generation are proposed respectively; the existing works of each are compared and analyzed. After that, an overview of the evaluation metrics in this specific domain is provided. Finally, the applications that deep graph generation enables are summarized and five promising future research directions are highlighted.
Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from using traditional methods to infer potential causal structures from observational data to the field of pattern recognition involved in deep learning. The rapid accumulation of massive data promotes the emergence of causal search methods with brilliant scalability. Existing summaries of causal discovery methods mainly focus on traditional methods based on constraints, scores and FCMs, there is a lack of perfect sorting and elaboration for deep learning-based methods, also lacking some considers and exploration of causal discovery methods from the perspective of variable paradigms. Therefore, we divide the possible causal discovery tasks into three types according to the variable paradigm and give the definitions of the three tasks respectively, define and instantiate the relevant datasets for each task and the final causal model constructed at the same time, then reviews the main existing causal discovery methods for different tasks. Finally, we propose some roadmaps from different perspectives for the current research gaps in the field of causal discovery and point out future research directions.
Generating texts which express complex ideas spanning multiple sentences requires a structured representation of their content (document plan), but these representations are prohibitively expensive to manually produce. In this work, we address the problem of generating coherent multi-sentence texts from the output of an information extraction system, and in particular a knowledge graph. Graphical knowledge representations are ubiquitous in computing, but pose a significant challenge for text generation techniques due to their non-hierarchical nature, collapsing of long-distance dependencies, and structural variety. We introduce a novel graph transforming encoder which can leverage the relational structure of such knowledge graphs without imposing linearization or hierarchical constraints. Incorporated into an encoder-decoder setup, we provide an end-to-end trainable system for graph-to-text generation that we apply to the domain of scientific text. Automatic and human evaluations show that our technique produces more informative texts which exhibit better document structure than competitive encoder-decoder methods.