Weakly Supervised Semantic Segmentation (WSSS) with only image-level supervision has garnered increasing attention due to its low annotation cost compared to pixel-level annotation. Most existing methods rely on Class Activation Maps (CAM) to generate pixel-level pseudo labels for supervised training. However, it is well known that CAM often suffers from partial activation -- activating the most discriminative part instead of the entire object area, and false activation -- unnecessarily activating the background around the object. In this study, we introduce a simple yet effective approach to address these limitations by harnessing the recently released Segment Anything Model (SAM) to generate higher-quality pseudo labels with CAM. SAM is a segmentation foundation model that demonstrates strong zero-shot ability in partitioning images into segments but lacks semantic labels for these regions. To circumvent this, we employ pseudo labels for a specific class as the signal to select the most relevant masks and label them to generate the refined pseudo labels for this class. The segments generated by SAM are highly precise, leading to substantial improvements in partial and false activation. Moreover, existing post-processing modules for producing pseudo labels, such as AffinityNet, are often computationally heavy, with a significantly long training time. Surprisingly, we discovered that using the initial CAM with SAM can achieve on-par performance as the post-processed pseudo label generated from these modules with much less computational cost. Our approach is highly versatile and capable of seamless integration into existing WSSS models without modification to base networks or pipelines. Despite its simplicity, our approach improves the mean Intersection over Union (mIoU) of pseudo labels from five state-of-the-art WSSS methods by 6.2\% on average on the PASCAL VOC 2012 dataset.
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Medical image segmentation of gadolinium enhancement magnetic resonance imaging (GE MRI) is an important task in clinical applications. However, manual annotation is time-consuming and requires specialized expertise. Semi-supervised segmentation methods that leverage both labeled and unlabeled data have shown promise, with contrastive learning emerging as a particularly effective approach. In this paper, we propose a contrastive learning strategy of foreground and background representations for semi-supervised 3D medical image segmentation (FBA-Net). Specifically, we leverage the contrastive loss to learn representations of both the foreground and background regions in the images. By training the network to distinguish between foreground-background pairs, we aim to learn a representation that can effectively capture the anatomical structures of interest. Experiments on three medical segmentation datasets demonstrate state-of-the-art performance. Notably, our method achieves a Dice score of 91.31% with only 20% labeled data, which is remarkably close to the 91.62% score of the fully supervised method that uses 100% labeled data on the left atrium dataset. Our framework has the potential to advance the field of semi-supervised 3D medical image segmentation and enable more efficient and accurate analysis of medical images with a limited amount of annotated labels.
For the task of semantic segmentation (SS) under domain shift, active learning (AL) acquisition strategies based on image regions and pseudo labels are state-of-the-art (SoA). The presence of diverse pseudo-labels within a region identifies pixels between different classes, which is a labeling efficient active learning data acquisition strategy. However, by design, pseudo-label variations are limited to only select the contours of classes, limiting the final AL performance. We approach AL for SS in the Poincar\'e hyperbolic ball model for the first time and leverage the variations of the radii of pixel embeddings within regions as a novel data acquisition strategy. This stems from a novel geometric property of a hyperbolic space trained without enforced hierarchies, which we experimentally prove. Namely, classes are mapped into compact hyperbolic areas with a comparable intra-class radii variance, as the model places classes of increasing explainable difficulty at denser hyperbolic areas, i.e. closer to the Poincar\'e ball edge. The variation of pixel embedding radii identifies well the class contours, but they also select a few intra-class peculiar details, which boosts the final performance. Our proposed HALO (Hyperbolic Active Learning Optimization) surpasses the supervised learning performance for the first time in AL for SS under domain shift, by only using a small portion of labels (i.e., 1%). The extensive experimental analysis is based on two established benchmarks, i.e. GTAV $\rightarrow$ Cityscapes and SYNTHIA $\rightarrow$ Cityscapes, where we set a new SoA. The code will be released.
The Segment Anything Model (SAM) has recently emerged as a groundbreaking model in the field of image segmentation. Nevertheless, both the original SAM and its medical adaptations necessitate slice-by-slice annotations, which directly increase the annotation workload with the size of the dataset. We propose MedLSAM to address this issue, ensuring a constant annotation workload irrespective of dataset size and thereby simplifying the annotation process. Our model introduces a few-shot localization framework capable of localizing any target anatomical part within the body. To achieve this, we develop a Localize Anything Model for 3D Medical Images (MedLAM), utilizing two self-supervision tasks: relative distance regression (RDR) and multi-scale similarity (MSS) across a comprehensive dataset of 14,012 CT scans. We then establish a methodology for accurate segmentation by integrating MedLAM with SAM. By annotating only six extreme points across three directions on a few templates, our model can autonomously identify the target anatomical region on all data scheduled for annotation. This allows our framework to generate a 2D bounding box for every slice of the image, which are then leveraged by SAM to carry out segmentations. We conducted experiments on two 3D datasets covering 38 organs and found that MedLSAM matches the performance of SAM and its medical adaptations while requiring only minimal extreme point annotations for the entire dataset. Furthermore, MedLAM has the potential to be seamlessly integrated with future 3D SAM models, paving the way for enhanced performance. Our code is public at \href{//github.com/openmedlab/MedLSAM}{//github.com/openmedlab/MedLSAM}.
Video anomaly detection under weak supervision is challenging due to the absence of frame-level annotations during the training phase. Previous work has employed graph convolution networks or self-attention mechanisms to model temporal relations, along with multiple instance learning (MIL)-based classification loss to learn discriminative features. However, most of them utilize multi-branches to capture local and global dependencies separately, leading to increased parameters and computational cost. Furthermore, the binarized constraint of the MIL-based loss only ensures coarse-grained interclass separability, ignoring fine-grained discriminability within anomalous classes. In this paper, we propose a weakly supervised anomaly detection framework that emphasizes efficient context modeling and enhanced semantic discriminability. To this end, we first construct a temporal context aggregation (TCA) module that captures complete contextual information by reusing similarity matrix and adaptive fusion. Additionally, we propose a prompt-enhanced learning (PEL) module that incorporates semantic priors into the model by utilizing knowledge-based prompts, aiming at enhancing the discriminative capacity of context features while ensuring separability between anomaly sub-classes. Furthermore, we introduce a score smoothing (SS) module in the testing phase to suppress individual bias and reduce false alarms. Extensive experiments demonstrate the effectiveness of various components of our method, which achieves competitive performance with fewer parameters and computational effort on three challenging benchmarks: the UCF-crime, XD-violence, and ShanghaiTech datasets. The detection accuracy of some anomaly sub-classes is also improved with a great margin.
Semi-supervised learning has demonstrated great potential in medical image segmentation by utilizing knowledge from unlabeled data. However, most existing approaches do not explicitly capture high-level semantic relations between distant regions, which limits their performance. In this paper, we focus on representation learning for semi-supervised learning, by developing a novel Multi-Scale Cross Supervised Contrastive Learning (MCSC) framework, to segment structures in medical images. We jointly train CNN and Transformer models, regularising their features to be semantically consistent across different scales. Our approach contrasts multi-scale features based on ground-truth and cross-predicted labels, in order to extract robust feature representations that reflect intra- and inter-slice relationships across the whole dataset. To tackle class imbalance, we take into account the prevalence of each class to guide contrastive learning and ensure that features adequately capture infrequent classes. Extensive experiments on two multi-structure medical segmentation datasets demonstrate the effectiveness of MCSC. It not only outperforms state-of-the-art semi-supervised methods by more than 3.0% in Dice, but also greatly reduces the performance gap with fully supervised methods.
Partially-supervised instance segmentation is a task which requests segmenting objects from novel unseen categories via learning on limited seen categories with annotated masks thus eliminating demands of heavy annotation burden. The key to addressing this task is to build an effective class-agnostic mask segmentation model. Unlike previous methods that learn such models only on seen categories, in this paper, we propose a new method, named ContrastMask, which learns a mask segmentation model on both seen and unseen categories under a unified pixel-level contrastive learning framework. In this framework, annotated masks of seen categories and pseudo masks of unseen categories serve as a prior for contrastive learning, where features from the mask regions (foreground) are pulled together, and are contrasted against those from the background, and vice versa. Through this framework, feature discrimination between foreground and background is largely improved, facilitating learning of the class-agnostic mask segmentation model. Exhaustive experiments on the COCO dataset demonstrate the superiority of our method, which outperforms previous state-of-the-arts.
What matters for contrastive learning? We argue that contrastive learning heavily relies on informative features, or "hard" (positive or negative) features. Early works include more informative features by applying complex data augmentations and large batch size or memory bank, and recent works design elaborate sampling approaches to explore informative features. The key challenge toward exploring such features is that the source multi-view data is generated by applying random data augmentations, making it infeasible to always add useful information in the augmented data. Consequently, the informativeness of features learned from such augmented data is limited. In response, we propose to directly augment the features in latent space, thereby learning discriminative representations without a large amount of input data. We perform a meta learning technique to build the augmentation generator that updates its network parameters by considering the performance of the encoder. However, insufficient input data may lead the encoder to learn collapsed features and therefore malfunction the augmentation generator. A new margin-injected regularization is further added in the objective function to avoid the encoder learning a degenerate mapping. To contrast all features in one gradient back-propagation step, we adopt the proposed optimization-driven unified contrastive loss instead of the conventional contrastive loss. Empirically, our method achieves state-of-the-art results on several benchmark datasets.
Image-level weakly supervised semantic segmentation (WSSS) is a fundamental yet challenging computer vision task facilitating scene understanding and automatic driving. Most existing methods resort to classification-based Class Activation Maps (CAMs) to play as the initial pseudo labels, which tend to focus on the discriminative image regions and lack customized characteristics for the segmentation task. To alleviate this issue, we propose a novel activation modulation and recalibration (AMR) scheme, which leverages a spotlight branch and a compensation branch to obtain weighted CAMs that can provide recalibration supervision and task-specific concepts. Specifically, an attention modulation module (AMM) is employed to rearrange the distribution of feature importance from the channel-spatial sequential perspective, which helps to explicitly model channel-wise interdependencies and spatial encodings to adaptively modulate segmentation-oriented activation responses. Furthermore, we introduce a cross pseudo supervision for dual branches, which can be regarded as a semantic similar regularization to mutually refine two branches. Extensive experiments show that AMR establishes a new state-of-the-art performance on the PASCAL VOC 2012 dataset, surpassing not only current methods trained with the image-level of supervision but also some methods relying on stronger supervision, such as saliency label. Experiments also reveal that our scheme is plug-and-play and can be incorporated with other approaches to boost their performance.
A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8% of benchmark performance using only two labeled MRI volumes for training, corresponding to only 4% (for ACDC) of the training data used to train the benchmark.
Deep Convolutional Neural Networks have pushed the state-of-the art for semantic segmentation provided that a large amount of images together with pixel-wise annotations is available. Data collection is expensive and a solution to alleviate it is to use transfer learning. This reduces the amount of annotated data required for the network training but it does not get rid of this heavy processing step. We propose a method of transfer learning without annotations on the target task for datasets with redundant content and distinct pixel distributions. Our method takes advantage of the approximate content alignment of the images between two datasets when the approximation error prevents the reuse of annotation from one dataset to another. Given the annotations for only one dataset, we train a first network in a supervised manner. This network autonomously learns to generate deep data representations relevant to the semantic segmentation. Then the images in the new dataset, we train a new network to generate a deep data representation that matches the one from the first network on the previous dataset. The training consists in a regression between feature maps and does not require any annotations on the new dataset. We show that this method reaches performances similar to a classic transfer learning on the PASCAL VOC dataset with synthetic transformations.
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