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Brain tumor growth is unique to each glioma patient and extends beyond what is visible in imaging scans, infiltrating surrounding brain tissue. Understanding these hidden patient-specific progressions is essential for effective therapies. Current treatment plans for brain tumors, such as radiotherapy, typically involve delineating a uniform margin around the visible tumor on pre-treatment scans to target this invisible tumor growth. This "one size fits all" approach is derived from population studies and often fails to account for the nuances of individual patient conditions. We present the GliODIL framework, which infers the full spatial distribution of tumor cell concentration from available multi-modal imaging, leveraging a Fisher-Kolmogorov type physics model to describe tumor growth. This is achieved through the newly introduced method of Optimizing the Discrete Loss (ODIL), where both data and physics-based constraints are softly assimilated into the solution. Our test dataset comprises 152 glioblastoma patients with pre-treatment imaging and post-treatment follow-ups for tumor recurrence monitoring. By blending data-driven techniques with physics-based constraints, GliODIL enhances recurrence prediction in radiotherapy planning, challenging traditional uniform margins and strict adherence to the Fisher-Kolmogorov partial differential equation (PDE) model, which is adapted for complex cases.

When addressing the challenge of complex multi-objective optimization problems, particularly those with non-convex and non-uniform Pareto fronts, Decomposition-based Multi-Objective Evolutionary Algorithms (MOEADs) often converge to local optima, thereby limiting solution diversity. Despite its significance, this issue has received limited theoretical exploration. Through a comprehensive geometric analysis, we identify that the traditional method of Reference Point (RP) selection fundamentally contributes to this challenge. In response, we introduce an innovative RP selection strategy, the Weight Vector-Guided and Gaussian-Hybrid method, designed to overcome the local optima issue. This approach employs a novel RP type that aligns with weight vector directions and integrates a Gaussian distribution to combine three distinct RP categories. Our research comprises two main experimental components: an ablation study involving 14 algorithms within the MOEADs framework, spanning from 2014 to 2022, to validate our theoretical framework, and a series of empirical tests to evaluate the effectiveness of our proposed method against both traditional and cutting-edge alternatives. Results demonstrate that our method achieves remarkable improvements in both population diversity and convergence.

The VT and Helberg codes, both in binary and non-binary forms, stand as elegant solutions for rectifying insertion and deletion errors. In this paper we consider the quaternary versions of these codes. It is well known that many optimal binary non-linear codes like Kerdock and Prepreta can be depicted as Gray images (isometry) of codes defined over $\mathbb{Z}_4$. Thus a natural question arises: Can we find similar maps between quaternary and binary spaces which gives interesting properties when applied to the VT and Helberg codes. We found several such maps called Naisargik (natural) maps and we study the images of quaternary VT and Helberg codes under these maps. Naisargik and inverse Naisargik images gives interesting error-correcting properties for VT and Helberg codes. If two Naisargik images of VT code generates an intersecting one deletion sphere, then the images holds the same weights. A quaternary Helberg code designed to correct $s$ deletions can effectively rectify $s+1$ deletion errors when considering its Naisargik image, and $s$-deletion correcting binary Helberg code can corrects $\lfloor\frac{s}{2}\rfloor$ errors with inverse Naisargik image.

Modeling the kinematics and dynamics of robotics systems with suspended loads using dual quaternions has not been explored so far. This paper introduces a new innovative control strategy using dual quaternions for UAVs with cable-suspended loads, focusing on the sling load lifting and tracking problems. By utilizing the mathematical efficiency and compactness of dual quaternions, a unified representation of the UAV and its suspended load's dynamics and kinematics is achieved, facilitating the realization of load lifting and trajectory tracking. The simulation results have tested the proposed strategy's accuracy, efficiency, and robustness. This study makes a substantial contribution to present this novel control strategy that harnesses the benefits of dual quaternions for cargo UAVs. Our work also holds promise for inspiring future innovations in under-actuated systems control using dual quaternions.

Adversarial attacks on machine learning algorithms have been a key deterrent to the adoption of AI in many real-world use cases. They significantly undermine the ability of high-performance neural networks by forcing misclassifications. These attacks introduce minute and structured perturbations or alterations in the test samples, imperceptible to human annotators in general, but trained neural networks and other models are sensitive to it. Historically, adversarial attacks have been first identified and studied in the domain of image processing. In this paper, we study adversarial examples in the field of natural language processing, specifically text classification tasks. We investigate the reasons for adversarial vulnerability, particularly in relation to the inherent dimensionality of the model. Our key finding is that there is a very strong correlation between the embedding dimensionality of the adversarial samples and their effectiveness on models tuned with input samples with same embedding dimension. We utilize this sensitivity to design an adversarial defense mechanism. We use ensemble models of varying inherent dimensionality to thwart the attacks. This is tested on multiple datasets for its efficacy in providing robustness. We also study the problem of measuring adversarial perturbation using different distance metrics. For all of the aforementioned studies, we have run tests on multiple models with varying dimensionality and used a word-vector level adversarial attack to substantiate the findings.

Coding theory revolves around the incorporation of redundancy into transmitted symbols, computation tasks, and stored data to guard against adversarial manipulation. However, error correction in coding theory is contingent upon a strict trust assumption. In the context of computation and storage, it is required that honest nodes outnumber adversarial ones by a certain margin. However, in several emerging real-world cases, particularly, in decentralized blockchain-oriented applications, such assumptions are often unrealistic. Consequently, despite the important role of coding in addressing significant challenges within decentralized systems, its applications become constrained. Still, in decentralized platforms, a distinctive characteristic emerges, offering new avenues for secure coding beyond the constraints of conventional methods. In these scenarios, the adversary benefits when the legitimate decoder recovers the data, and preferably with a high estimation error. This incentive motivates them to act rationally, trying to maximize their gains. In this paper, we propose a game theoretic formulation for coding, called the game of coding, that captures this unique dynamic where each of the adversary and the data collector (decoder) have a utility function to optimize. The utility functions reflect the fact that both the data collector and the adversary are interested in increasing the chance of data being recoverable by the data collector. Moreover, the utility functions express the interest of the data collector to estimate the input with lower estimation error, but the opposite interest of the adversary. As a first, still highly non-trivial step, we characterize the equilibrium of the game for the repetition code with a repetition factor of 2, for a wide class of utility functions with minimal assumptions.

One of the current challenges in physically-based simulations, and, more specifically, fluid simulations, is to produce visually appealing results at interactive rates, capable of being used in multiple forms of media. In recent times, a lot of effort has been made with regards to this with the use of multi-core architectures, as many of the computations involved in the algorithms for these simulations are very well suited for these architectures. Although there is a considerable amount of works regarding acceleration techniques in this field, there is yet room to further explore and analyze some of them. To investigate this problem, we surveyed the topic of fluid simulations and some of the recent contributions towards this field. Additionally, we implemented two versions of a fluid simulation algorithm, one on the CPU and the other on the GPU using NVIDIA's CUDA framework, with the intent of gaining a better understanding of the effort needed to move these simulations to a multi-core architecture and the performance gains that we get with it.

We study evaluating a policy under best- and worst-case perturbations to a Markov decision process (MDP), given transition observations from the original MDP, whether under the same or different policy. This is an important problem when there is the possibility of a shift between historical and future environments, due to e.g. unmeasured confounding, distributional shift, or an adversarial environment. We propose a perturbation model that can modify transition kernel densities up to a given multiplicative factor or its reciprocal, which extends the classic marginal sensitivity model (MSM) for single time step decision making to infinite-horizon RL. We characterize the sharp bounds on policy value under this model, that is, the tightest possible bounds given by the transition observations from the original MDP, and we study the estimation of these bounds from such transition observations. We develop an estimator with several appealing guarantees: it is semiparametrically efficient, and remains so even when certain necessary nuisance functions such as worst-case Q-functions are estimated at slow nonparametric rates. It is also asymptotically normal, enabling easy statistical inference using Wald confidence intervals. In addition, when certain nuisances are estimated inconsistently we still estimate a valid, albeit possibly not sharp bounds on the policy value. We validate these properties in numeric simulations. The combination of accounting for environment shifts from train to test (robustness), being insensitive to nuisance-function estimation (orthogonality), and accounting for having only finite samples to learn from (inference) together leads to credible and reliable policy evaluation.

Existing recommender systems extract the user preference based on learning the correlation in data, such as behavioral correlation in collaborative filtering, feature-feature, or feature-behavior correlation in click-through rate prediction. However, regretfully, the real world is driven by causality rather than correlation, and correlation does not imply causation. For example, the recommender systems can recommend a battery charger to a user after buying a phone, in which the latter can serve as the cause of the former, and such a causal relation cannot be reversed. Recently, to address it, researchers in recommender systems have begun to utilize causal inference to extract causality, enhancing the recommender system. In this survey, we comprehensively review the literature on causal inference-based recommendation. At first, we present the fundamental concepts of both recommendation and causal inference as the basis of later content. We raise the typical issues that the non-causality recommendation is faced. Afterward, we comprehensively review the existing work of causal inference-based recommendation, based on a taxonomy of what kind of problem causal inference addresses. Last, we discuss the open problems in this important research area, along with interesting future works.

Meta-reinforcement learning algorithms can enable robots to acquire new skills much more quickly, by leveraging prior experience to learn how to learn. However, much of the current research on meta-reinforcement learning focuses on task distributions that are very narrow. For example, a commonly used meta-reinforcement learning benchmark uses different running velocities for a simulated robot as different tasks. When policies are meta-trained on such narrow task distributions, they cannot possibly generalize to more quickly acquire entirely new tasks. Therefore, if the aim of these methods is to enable faster acquisition of entirely new behaviors, we must evaluate them on task distributions that are sufficiently broad to enable generalization to new behaviors. In this paper, we propose an open-source simulated benchmark for meta-reinforcement learning and multi-task learning consisting of 50 distinct robotic manipulation tasks. Our aim is to make it possible to develop algorithms that generalize to accelerate the acquisition of entirely new, held-out tasks. We evaluate 6 state-of-the-art meta-reinforcement learning and multi-task learning algorithms on these tasks. Surprisingly, while each task and its variations (e.g., with different object positions) can be learned with reasonable success, these algorithms struggle to learn with multiple tasks at the same time, even with as few as ten distinct training tasks. Our analysis and open-source environments pave the way for future research in multi-task learning and meta-learning that can enable meaningful generalization, thereby unlocking the full potential of these methods.