In pediatric cardiology, the accurate and immediate assessment of cardiac function through echocardiography is important since it can determine whether urgent intervention is required in many emergencies. However, echocardiography is characterized by ambiguity and heavy background noise interference, bringing more difficulty to accurate segmentation. Present methods lack efficiency and are also prone to mistakenly segmenting some background noise areas as the left ventricular area due to noise disturbance. To relieve the two issues, we introduce P-Mamba for efficient pediatric echocardiographic left ventricular segmentation. Specifically, we turn to the recently proposed vision mamba layers in our vision mamba encoder branch to improve the computing and memory efficiency of our model while modeling global dependencies. In the other DWT-based PMD encoder branch, we devise DWT-based Perona-Malik Diffusion (PMD) Blocks that utilize PMD for noise suppression, while simultaneously preserving the local shape cues of the left ventricle. Leveraging the strengths of both the two encoder branches, P-Mamba achieves superior accuracy and efficiency to established models, such as vision transformers with quadratic and linear computational complexity. This innovative approach promises significant advancements in pediatric cardiac imaging and beyond.
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In an era where the volume of data drives the effectiveness of self-supervised learning, the specificity and clarity of data semantics play a crucial role in model training. Addressing this, we introduce HYPerbolic Entailment filtering (HYPE), a novel methodology designed to meticulously extract modality-wise meaningful and well-aligned data from extensive, noisy image-text pair datasets. Our approach leverages hyperbolic embeddings and the concept of entailment cones to evaluate and filter out samples with meaningless or underspecified semantics, focusing on enhancing the specificity of each data sample. HYPE not only demonstrates a significant improvement in filtering efficiency but also sets a new state-of-the-art in the DataComp benchmark when combined with existing filtering techniques. This breakthrough showcases the potential of HYPE to refine the data selection process, thereby contributing to the development of more accurate and efficient self-supervised learning models. Additionally, the image specificity $\epsilon_{i}$ can be independently applied to induce an image-only dataset from an image-text or image-only data pool for training image-only self-supervised models and showed superior performance when compared to the dataset induced by CLIP score.
The proliferation of large language models (LLMs) and their integration into multi-agent systems has paved the way for sophisticated automation in various domains. This paper introduces AutoGenesisAgent, a multi-agent system that autonomously designs and deploys other multi-agent systems tailored for specific tasks. AutoGenesisAgent comprises several specialized agents including System Understanding, System Design, Agent Generator, and several others that collectively manage the lifecycle of creating functional multi-agent systems from initial concept to deployment. Each agent in AutoGenesisAgent has distinct responsibilities ranging from interpreting input prompts to optimizing system performance, culminating, in the deployment of a ready-to-use system. This proof-of-concept study discusses the design, implementation, and lessons learned from developing AutoGenesisAgent, highlighting its capability to generate and refine multi-agent systems autonomously, thereby reducing the need for extensive human oversight in the initial stages of system design. Keywords: multi-agent systems, large language models, system design automation, agent architecture, autonomous systems, software deployment
The biomedical field is among the sectors most impacted by the increasing regulation of Artificial Intelligence (AI) and data protection legislation, given the sensitivity of patient information. However, the rise of synthetic data generation methods offers a promising opportunity for data-driven technologies. In this study, we propose a statistical approach for synthetic data generation applicable in classification problems. We assess the utility and privacy implications of synthetic data generated by Kernel Density Estimator and K-Nearest Neighbors sampling (KDE-KNN) within a real-world context, specifically focusing on its application in sepsis detection. The detection of sepsis is a critical challenge in clinical practice due to its rapid progression and potentially life-threatening consequences. Moreover, we emphasize the benefits of KDE-KNN compared to current synthetic data generation methodologies. Additionally, our study examines the effects of incorporating synthetic data into model training procedures. This investigation provides valuable insights into the effectiveness of synthetic data generation techniques in mitigating regulatory constraints within the biomedical field.
Data imbalance in training data often leads to biased predictions from trained models, which in turn causes ethical and social issues. A straightforward solution is to carefully curate training data, but given the enormous scale of modern neural networks, this is prohibitively labor-intensive and thus impractical. Inspired by recent developments in generative models, this paper explores the potential of synthetic data to address the data imbalance problem. To be specific, our method, dubbed SYNAuG, leverages synthetic data to equalize the unbalanced distribution of training data. Our experiments demonstrate that, although a domain gap between real and synthetic data exists, training with SYNAuG followed by fine-tuning with a few real samples allows to achieve impressive performance on diverse tasks with different data imbalance issues, surpassing existing task-specific methods for the same purpose.
Current recommendation systems are significantly affected by a serious issue of temporal data shift, which is the inconsistency between the distribution of historical data and that of online data. Most existing models focus on utilizing updated data, overlooking the transferable, temporal data shift-free information that can be learned from shifting data. We propose the Temporal Invariance of Association theorem, which suggests that given a fixed search space, the relationship between the data and the data in the search space keeps invariant over time. Leveraging this principle, we designed a retrieval-based recommendation system framework that can train a data shift-free relevance network using shifting data, significantly enhancing the predictive performance of the original model in the recommendation system. However, retrieval-based recommendation models face substantial inference time costs when deployed online. To address this, we further designed a distill framework that can distill information from the relevance network into a parameterized module using shifting data. The distilled model can be deployed online alongside the original model, with only a minimal increase in inference time. Extensive experiments on multiple real datasets demonstrate that our framework significantly improves the performance of the original model by utilizing shifting data.
Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between natural and medical images in general and ultrasound images in particular hinders fine-tuning models trained on natural images to the task at hand. In this work, we address the performance degradation of segmentation models in low-data regimes and propose a prompt-less segmentation method harnessing the ability of segmentation foundation models to segment abstract shapes. We do that via our novel prompt point generation algorithm which uses coarse semantic segmentation masks as input and a zero-shot prompt-able foundation model as an optimization target. We demonstrate our method on a segmentation findings task (pathologic anomalies) in ultrasound images. Our method's advantages are brought to light in varying degrees of low-data regime experiments on a small-scale musculoskeletal ultrasound images dataset, yielding a larger performance gain as the training set size decreases.
Spiking neural networks drawing inspiration from biological constraints of the brain promise an energy-efficient paradigm for artificial intelligence. However, challenges exist in identifying guiding principles to train these networks in a robust fashion. In addition, training becomes an even more difficult problem when incorporating biological constraints of excitatory and inhibitory connections. In this work, we identify several key factors, such as low initial firing rates and diverse inhibitory spiking patterns, that determine the overall ability to train spiking networks with various ratios of excitatory to inhibitory neurons on AI-relevant datasets. The results indicate networks with the biologically realistic 80:20 excitatory:inhibitory balance can reliably train at low activity levels and in noisy environments. Additionally, the Van Rossum distance, a measure of spike train synchrony, provides insight into the importance of inhibitory neurons to increase network robustness to noise. This work supports further biologically-informed large-scale networks and energy efficient hardware implementations.
Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly difficult and costly to obtain especially in the medical imaging domain where only experts can provide reliable and accurate annotations. Semi-supervised learning has emerged as an appealing strategy and been widely applied to medical image segmentation tasks to train deep models with limited annotations. In this paper, we present a comprehensive review of recently proposed semi-supervised learning methods for medical image segmentation and summarized both the technical novelties and empirical results. Furthermore, we analyze and discuss the limitations and several unsolved problems of existing approaches. We hope this review could inspire the research community to explore solutions for this challenge and further promote the developments in medical image segmentation field.
The incredible development of federated learning (FL) has benefited various tasks in the domains of computer vision and natural language processing, and the existing frameworks such as TFF and FATE has made the deployment easy in real-world applications. However, federated graph learning (FGL), even though graph data are prevalent, has not been well supported due to its unique characteristics and requirements. The lack of FGL-related framework increases the efforts for accomplishing reproducible research and deploying in real-world applications. Motivated by such strong demand, in this paper, we first discuss the challenges in creating an easy-to-use FGL package and accordingly present our implemented package FederatedScope-GNN (FS-G), which provides (1) a unified view for modularizing and expressing FGL algorithms; (2) comprehensive DataZoo and ModelZoo for out-of-the-box FGL capability; (3) an efficient model auto-tuning component; and (4) off-the-shelf privacy attack and defense abilities. We validate the effectiveness of FS-G by conducting extensive experiments, which simultaneously gains many valuable insights about FGL for the community. Moreover, we employ FS-G to serve the FGL application in real-world E-commerce scenarios, where the attained improvements indicate great potential business benefits. We publicly release FS-G, as submodules of FederatedScope, at //github.com/alibaba/FederatedScope to promote FGL's research and enable broad applications that would otherwise be infeasible due to the lack of a dedicated package.
There recently has been a surge of interest in developing a new class of deep learning (DL) architectures that integrate an explicit time dimension as a fundamental building block of learning and representation mechanisms. In turn, many recent results show that topological descriptors of the observed data, encoding information on the shape of the dataset in a topological space at different scales, that is, persistent homology of the data, may contain important complementary information, improving both performance and robustness of DL. As convergence of these two emerging ideas, we propose to enhance DL architectures with the most salient time-conditioned topological information of the data and introduce the concept of zigzag persistence into time-aware graph convolutional networks (GCNs). Zigzag persistence provides a systematic and mathematically rigorous framework to track the most important topological features of the observed data that tend to manifest themselves over time. To integrate the extracted time-conditioned topological descriptors into DL, we develop a new topological summary, zigzag persistence image, and derive its theoretical stability guarantees. We validate the new GCNs with a time-aware zigzag topological layer (Z-GCNETs), in application to traffic forecasting and Ethereum blockchain price prediction. Our results indicate that Z-GCNET outperforms 13 state-of-the-art methods on 4 time series datasets.
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