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Reconfigurable intelligent surface (RIS)-aided terahertz (THz) communications have been regarded as a promising candidate for future 6G networks because of its ultra-wide bandwidth and ultra-low power consumption. However, there exists the beam split problem, especially when the base station (BS) or RIS owns the large-scale antennas, which may lead to serious array gain loss. Therefore, in this paper, we investigate the beam split and beamforming design problems in the THz RIS communications. Specifically, we first analyze the beam split effect caused by different RIS sizes, shapes and deployments. On this basis, we apply the fully connected time delayer phase shifter hybrid beamforming architecture at the BS and deploy distributed RISs to cooperatively mitigate the beam split effect. We aim to maximize the achievable sum rate by jointly optimizing the hybrid analog/digital beamforming, time delays at the BS and reflection coefficients at the RISs. To solve the formulated problem, we first design the analog beamforming and time delays based on different RISs physical directions, and then it is transformed into an optimization problem by jointly optimizing the digital beamforming and reflection coefficients. Next, we propose an alternatively iterative optimization algorithm to deal with it. Specifically, for given the reflection coefficients, we propose an iterative algorithm based on the minimum mean square error technique to obtain the digital beamforming. After, we apply LDR and MCQT methods to transform the original problem to a QCQP, which can be solved by ADMM technique to obtain the reflection coefficients. Finally, the digital beamforming and reflection coefficients are obtained via repeating the above processes until convergence. Simulation results verify that the proposed scheme can effectively alleviate the beam split effect and improve the system capacity.

This paper introduces discrete-holomorphic Perfectly Matched Layers (PMLs) specifically designed for high-order finite difference (FD) discretizations of the scalar wave equation. In contrast to standard PDE-based PMLs, the proposed method achieves the remarkable outcome of completely eliminating numerical reflections at the PML interface, in practice achieving errors at the level of machine precision. Our approach builds upon the ideas put forth in a recent publication [Journal of Computational Physics 381 (2019): 91-109] expanding the scope from the standard second-order FD method to arbitrary high-order schemes. This generalization uses additional localized PML variables to accommodate the larger stencils employed. We establish that the numerical solutions generated by our proposed schemes exhibit an exponential decay rate as they propagate within the PML domain. To showcase the effectiveness of our method, we present a variety of numerical examples, including waveguide problems. These examples highlight the importance of employing high-order schemes to effectively address and minimize undesired numerical dispersion errors, emphasizing the practical advantages and applicability of our approach.

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing the sum of the squared distances between actual observations and simulation outputs. It is shown in this paper that this method is inefficient, particularly when the epidemic models are developed based on certain simplifications of reality, also known as imperfect models which are commonly used in practice. To address this issue, a new estimator is introduced that is asymptotically consistent, has a smaller estimation variance than the least squares estimator, and achieves the semiparametric efficiency. Numerical studies are performed to examine the finite sample performance. The proposed method is applied to the analysis of the COVID-19 pandemic for 20 countries based on the SEIR (Susceptible-Exposed-Infectious-Recovered) model with both deterministic and stochastic simulations. The estimation of the parameters, including the basic reproduction number and the average incubation period, reveal the risk of disease outbreaks in each country and provide insights to the design of public health interventions.

A private cache-aided compression problem is studied, where a server has access to a database of $N$ files, $(Y_1,...,Y_N)$, each of size $F$ bits and is connected through a shared link to $K$ users, each equipped with a local cache of size $MF$ bits. In the placement phase, the server fills the users$'$ caches without knowing their demands, while the delivery phase takes place after the users send their demands to the server. We assume that each file $Y_i$ is arbitrarily correlated with a private attribute $X$, and an adversary is assumed to have access to the shared link. The users and the server have access to a shared key $W$. The goal is to design the cache contents and the delivered message $\cal C$ such that the average length of $\mathcal{C}$ is minimized, while satisfying: i. The response $\cal C$ does not reveal any information about $X$, i.e., $X$ and $\cal C$ are independent, which corresponds to the perfect privacy constraint; ii. User $i$ is able to decode its demand, $Y_{d_i}$, by using $\cal C$, its local cache $Z_i$, and the shared key $W$. Since the database is correlated with $X$, existing codes for cache-aided delivery do not satisfy the perfect privacy condition. Indeed, we propose a variable-length coding scheme that combines privacy-aware compression with coded caching techniques. In particular, we use two-part code construction and Functional Representation Lemma. Finally, we extend the results to the case, where $X$ and $\mathcal{C}$ can be correlated, i.e., non-zero leakage is allowed.

In this paper, we present distributed fault-tolerant algorithms that approximate the centroid of a set of n data points in $\mathbb{R}^d$. Our work falls into the broader area of approximate multidimensional Byzantine agreement. The standard approach used in existing algorithms is to agree on a vector inside the convex hull of all correct vectors. This strategy dismisses many possibly correct data points. As a result, the algorithm does not necessarily agree on a representative value. In fact, this does not allow us to compute a better approximation than $2d$ of the centroid in the synchronous case. To find better approximation algorithms for the centroid, we investigate the trade-off between the quality of the approximation, the resilience of the algorithm, and the validity of the solution. For the synchronous case, we show that it is possible to achieve a $1$-approximation of the centroid with up to $t<n/(d+1)$ Byzantine data points. This approach however does not give any guarantee on the validity of the solution. Therefore, we develop a second approach that reaches a $2\sqrt{d}$-approximation of the centroid, while satisfying the standard validity condition for agreement protocols. We are even able to restrict the validity condition to agreement inside the box of correct data points, while achieving optimal resilience of $t< n/3$. For the asynchronous case, we can adapt all three algorithms to reach the same approximation results (up to a constant factor). Our results suggest that it is reasonable to study the trade-off between validity conditions and the quality of the solution.

Voltage-gated sodium (Nav) channels constitute a prime target for drug design and discovery, given their implication in various diseases such as epilepsy, migraine and ataxia to name a few. In this regard, performing morphological analysis is a crucial step in comprehensively understanding their biological function and mechanism, as well as in uncovering subtle details of their mechanism that may be elusive to experimental observations. Despite their tremendous therapeutic potential, drug design resources are deficient, particularly in terms of accurate and comprehensive geometric information. This paper presents a geometric dataset of molecular surfaces that are representative of Nav channels in mammals. For each structure we provide three representations and a number of geometric measures, including length, volume and straightness of the recognized channels. To demonstrate the effective use of GEO-Nav, we have tested it on two methods belonging to two different categories of approaches: a sphere-based and a tessellation-based method.

The cornerstone of stroke care is expedient management that varies depending on the time since stroke onset. Consequently, clinical decision making is centered on accurate knowledge of timing and often requires a radiologist to interpret Computed Tomography (CT) of the brain to confirm the occurrence and age of an event. These tasks are particularly challenging due to the subtle expression of acute ischemic lesions and the dynamic nature of their appearance. Automation efforts have not yet applied deep learning to estimate lesion age and treated these two tasks independently, so, have overlooked their inherent complementary relationship. To leverage this, we propose a novel end-to-end multi-task transformer-based network optimized for concurrent segmentation and age estimation of cerebral ischemic lesions. By utilizing gated positional self-attention and CT-specific data augmentation, the proposed method can capture long-range spatial dependencies while maintaining its ability to be trained from scratch under low-data regimes commonly found in medical imaging. Furthermore, to better combine multiple predictions, we incorporate uncertainty by utilizing quantile loss to facilitate estimating a probability density function of lesion age. The effectiveness of our model is then extensively evaluated on a clinical dataset consisting of 776 CT images from two medical centers. Experimental results demonstrate that our method obtains promising performance, with an area under the curve (AUC) of 0.933 for classifying lesion ages <=4.5 hours compared to 0.858 using a conventional approach, and outperforms task-specific state-of-the-art algorithms.

We present DeepMVI, a deep learning method for missing value imputation in multidimensional time-series datasets. Missing values are commonplace in decision support platforms that aggregate data over long time stretches from disparate sources, and reliable data analytics calls for careful handling of missing data. One strategy is imputing the missing values, and a wide variety of algorithms exist spanning simple interpolation, matrix factorization methods like SVD, statistical models like Kalman filters, and recent deep learning methods. We show that often these provide worse results on aggregate analytics compared to just excluding the missing data. DeepMVI uses a neural network to combine fine-grained and coarse-grained patterns along a time series, and trends from related series across categorical dimensions. After failing with off-the-shelf neural architectures, we design our own network that includes a temporal transformer with a novel convolutional window feature, and kernel regression with learned embeddings. The parameters and their training are designed carefully to generalize across different placements of missing blocks and data characteristics. Experiments across nine real datasets, four different missing scenarios, comparing seven existing methods show that DeepMVI is significantly more accurate, reducing error by more than 50% in more than half the cases, compared to the best existing method. Although slower than simpler matrix factorization methods, we justify the increased time overheads by showing that DeepMVI is the only option that provided overall more accurate analytics than dropping missing values.

We propose novel deep joint source-channel coding (DeepJSCC) algorithms for wireless image transmission over multi-input multi-output (MIMO) Rayleigh fading channels, when channel state information (CSI) is available only at the receiver. We consider two different schemes; one exploiting the spatial diversity and the other exploiting the spatial multiplexing gain of the MIMO channel, respectively. For the former, we utilize an orthogonal space-time block code (OSTBC) to achieve full diversity and increase the robustness against channel variations. In the latter, we directly map the input to the antennas, where the additional degree of freedom can be used to send more information about the source signal. Simulation results show that the diversity scheme outperforms the multiplexing scheme for lower signal-to-noise ratio (SNR) values and a smaller number of receive antennas at the AP. When the number of transmit antennas is greater than two, however, the full-diversity scheme becomes less beneficial. We also show that both the diversity and multiplexing schemes can achieve comparable performance with the state-of-the-art BPG algorithm delivered at the instantaneous capacity of the MIMO channel, which serves as an upper bound on the performance of separation-based practical systems.

Residual networks (ResNets) have displayed impressive results in pattern recognition and, recently, have garnered considerable theoretical interest due to a perceived link with neural ordinary differential equations (neural ODEs). This link relies on the convergence of network weights to a smooth function as the number of layers increases. We investigate the properties of weights trained by stochastic gradient descent and their scaling with network depth through detailed numerical experiments. We observe the existence of scaling regimes markedly different from those assumed in neural ODE literature. Depending on certain features of the network architecture, such as the smoothness of the activation function, one may obtain an alternative ODE limit, a stochastic differential equation or neither of these. These findings cast doubts on the validity of the neural ODE model as an adequate asymptotic description of deep ResNets and point to an alternative class of differential equations as a better description of the deep network limit.