As a basic task in computer vision, semantic segmentation can provide fundamental information for object detection and instance segmentation to help the artificial intelligence better understand real world. Since the proposal of fully convolutional neural network (FCNN), it has been widely used in semantic segmentation because of its high accuracy of pixel-wise classification as well as high precision of localization. In this paper, we apply several famous FCNN to brain tumor segmentation, making comparisons and adjusting network architectures to achieve better performance measured by metrics such as precision, recall, mean of intersection of union (mIoU) and dice score coefficient (DSC). The adjustments to the classic FCNN include adding more connections between convolutional layers, enlarging decoders after up sample layers and changing the way shallower layers' information is reused. Besides the structure modification, we also propose a new classifier with a hierarchical dice loss. Inspired by the containing relationship between classes, the loss function converts multiple classification to multiple binary classification in order to counteract the negative effect caused by imbalance data set. Massive experiments have been done on the training set and testing set in order to assess our refined fully convolutional neural networks and new types of loss function. Competitive figures prove they are more effective than their predecessors.
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U-Net has been providing state-of-the-art performance in many medical image segmentation problems. Many modifications have been proposed for U-Net, such as attention U-Net, recurrent residual convolutional U-Net (R2-UNet), and U-Net with residual blocks or blocks with dense connections. However, all these modifications have an encoder-decoder structure with skip connections, and the number of paths for information flow is limited. We propose LadderNet in this paper, which can be viewed as a chain of multiple U-Nets. Instead of only one pair of encoder branch and decoder branch in U-Net, a LadderNet has multiple pairs of encoder-decoder branches, and has skip connections between every pair of adjacent decoder and decoder branches in each level. Inspired by the success of ResNet and R2-UNet, we use modified residual blocks where two convolutional layers in one block share the same weights. A LadderNet has more paths for information flow because of skip connections and residual blocks, and can be viewed as an ensemble of Fully Convolutional Networks (FCN). The equivalence to an ensemble of FCNs improves segmentation accuracy, while the shared weights within each residual block reduce parameter number. Semantic segmentation is essential for retinal disease detection. We tested LadderNet on two benchmark datasets for blood vessel segmentation in retinal images, and achieved superior performance over methods in the literature. The implementation is provided \url{//github.com/juntang-zhuang/LadderNet}
Radiologist is "doctor's doctor", biomedical image segmentation plays a central role in quantitative analysis, clinical diagnosis, and medical intervention. In the light of the fully convolutional networks (FCN) and U-Net, deep convolutional networks (DNNs) have made significant contributions in biomedical image segmentation applications. In this paper, based on U-Net, we propose MDUnet, a multi-scale densely connected U-net for biomedical image segmentation. we propose three different multi-scale dense connections for U shaped architectures encoder, decoder and across them. The highlights of our architecture is directly fuses the neighboring different scale feature maps from both higher layers and lower layers to strengthen feature propagation in current layer. Which can largely improves the information flow encoder, decoder and across them. Multi-scale dense connections, which means containing shorter connections between layers close to the input and output, also makes much deeper U-net possible. We adopt the optimal model based on the experiment and propose a novel Multi-scale Dense U-Net (MDU-Net) architecture with quantization. Which reduce overfitting in MDU-Net for better accuracy. We evaluate our purpose model on the MICCAI 2015 Gland Segmentation dataset (GlaS). The three multi-scale dense connections improve U-net performance by up to 1.8% on test A and 3.5% on test B in the MICCAI Gland dataset. Meanwhile the MDU-net with quantization achieves the superiority over U-Net performance by up to 3% on test A and 4.1% on test B.
In recent years, the sequence-to-sequence learning neural networks with attention mechanism have achieved great progress. However, there are still challenges, especially for Neural Machine Translation (NMT), such as lower translation quality on long sentences. In this paper, we present a hierarchical deep neural network architecture to improve the quality of long sentences translation. The proposed network embeds sequence-to-sequence neural networks into a two-level category hierarchy by following the coarse-to-fine paradigm. Long sentences are input by splitting them into shorter sequences, which can be well processed by the coarse category network as the long distance dependencies for short sentences is able to be handled by network based on sequence-to-sequence neural network. Then they are concatenated and corrected by the fine category network. The experiments shows that our method can achieve superior results with higher BLEU(Bilingual Evaluation Understudy) scores, lower perplexity and better performance in imitating expression style and words usage than the traditional networks.
We present an end-to-end method for the task of panoptic segmentation. The method makes instance segmentation and semantic segmentation predictions in a single network, and combines these outputs using heuristics to create a single panoptic segmentation output. The architecture consists of a ResNet-50 feature extractor shared by the semantic segmentation and instance segmentation branch. For instance segmentation, a Mask R-CNN type of architecture is used, while the semantic segmentation branch is augmented with a Pyramid Pooling Module. Results for this method are submitted to the COCO and Mapillary Joint Recognition Challenge 2018. Our approach achieves a PQ score of 17.6 on the Mapillary Vistas validation set and 27.2 on the COCO test-dev set.
Deep neural network architectures have traditionally been designed and explored with human expertise in a long-lasting trial-and-error process. This process requires huge amount of time, expertise, and resources. To address this tedious problem, we propose a novel algorithm to optimally find hyperparameters of a deep network architecture automatically. We specifically focus on designing neural architectures for medical image segmentation task. Our proposed method is based on a policy gradient reinforcement learning for which the reward function is assigned a segmentation evaluation utility (i.e., dice index). We show the efficacy of the proposed method with its low computational cost in comparison with the state-of-the-art medical image segmentation networks. We also present a new architecture design, a densely connected encoder-decoder CNN, as a strong baseline architecture to apply the proposed hyperparameter search algorithm. We apply the proposed algorithm to each layer of the baseline architectures. As an application, we train the proposed system on cine cardiac MR images from Automated Cardiac Diagnosis Challenge (ACDC) MICCAI 2017. Starting from a baseline segmentation architecture, the resulting network architecture obtains the state-of-the-art results in accuracy without performing any trial-and-error based architecture design approaches or close supervision of the hyperparameters changes.
For the challenging semantic image segmentation task the most efficient models have traditionally combined the structured modelling capabilities of Conditional Random Fields (CRFs) with the feature extraction power of CNNs. In more recent works however, CRF post-processing has fallen out of favour. We argue that this is mainly due to the slow training and inference speeds of CRFs, as well as the difficulty of learning the internal CRF parameters. To overcome both issues we propose to add the assumption of conditional independence to the framework of fully-connected CRFs. This allows us to reformulate the inference in terms of convolutions, which can be implemented highly efficiently on GPUs. Doing so speeds up inference and training by a factor of more then 100. All parameters of the convolutional CRFs can easily be optimized using backpropagation. To facilitating further CRF research we make our implementation publicly available. Please visit: //github.com/MarvinTeichmann/ConvCRF
State-of-the-art semantic segmentation approaches increase the receptive field of their models by using either a downsampling path composed of poolings/strided convolutions or successive dilated convolutions. However, it is not clear which operation leads to best results. In this paper, we systematically study the differences introduced by distinct receptive field enlargement methods and their impact on the performance of a novel architecture, called Fully Convolutional DenseResNet (FC-DRN). FC-DRN has a densely connected backbone composed of residual networks. Following standard image segmentation architectures, receptive field enlargement operations that change the representation level are interleaved among residual networks. This allows the model to exploit the benefits of both residual and dense connectivity patterns, namely: gradient flow, iterative refinement of representations, multi-scale feature combination and deep supervision. In order to highlight the potential of our model, we test it on the challenging CamVid urban scene understanding benchmark and make the following observations: 1) downsampling operations outperform dilations when the model is trained from scratch, 2) dilations are useful during the finetuning step of the model, 3) coarser representations require less refinement steps, and 4) ResNets (by model construction) are good regularizers, since they can reduce the model capacity when needed. Finally, we compare our architecture to alternative methods and report state-of-the-art result on the Camvid dataset, with at least twice fewer parameters.
Glaucoma is a chronic eye disease that leads to irreversible vision loss. The cup to disc ratio (CDR) plays an important role in the screening and diagnosis of glaucoma. Thus, the accurate and automatic segmentation of optic disc (OD) and optic cup (OC) from fundus images is a fundamental task. Most existing methods segment them separately, and rely on hand-crafted visual feature from fundus images. In this paper, we propose a deep learning architecture, named M-Net, which solves the OD and OC segmentation jointly in a one-stage multi-label system. The proposed M-Net mainly consists of multi-scale input layer, U-shape convolutional network, side-output layer, and multi-label loss function. The multi-scale input layer constructs an image pyramid to achieve multiple level receptive field sizes. The U-shape convolutional network is employed as the main body network structure to learn the rich hierarchical representation, while the side-output layer acts as an early classifier that produces a companion local prediction map for different scale layers. Finally, a multi-label loss function is proposed to generate the final segmentation map. For improving the segmentation performance further, we also introduce the polar transformation, which provides the representation of the original image in the polar coordinate system. The experiments show that our M-Net system achieves state-of-the-art OD and OC segmentation result on ORIGA dataset. Simultaneously, the proposed method also obtains the satisfactory glaucoma screening performances with calculated CDR value on both ORIGA and SCES datasets.
Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for 6-month infant brain, due to the poor image quality, among other difficulties inherent to infant brain MRI, e.g., the isointense contrast between white and gray matter and the severe partial volume effect due to small brain sizes. This study investigates the problem with an ensemble of semi-dense fully convolutional neural networks (CNNs), which employs T1-weighted and T2-weighted MR images as input. We demonstrate that the ensemble agreement is highly correlated with the segmentation errors. Therefore, our method provides measures that can guide local user corrections. To the best of our knowledge, this work is the first ensemble of 3D CNNs for suggesting annotations within images. Furthermore, inspired by the very recent success of dense networks, we propose a novel architecture, SemiDenseNet, which connects all convolutional layers directly to the end of the network. Our architecture allows the efficient propagation of gradients during training, while limiting the number of parameters, requiring one order of magnitude less parameters than popular medical image segmentation networks such as 3D U-Net. Another contribution of our work is the study of the impact that early or late fusions of multiple image modalities might have on the performances of deep architectures. We report evaluations of our method on the public data of the MICCAI iSEG-2017 Challenge on 6-month infant brain MRI segmentation, and show very competitive results among 21 teams, ranking first or second in most metrics.
Convolutional networks are powerful visual models that yield hierarchies of features. We show that convolutional networks by themselves, trained end-to-end, pixels-to-pixels, exceed the state-of-the-art in semantic segmentation. Our key insight is to build "fully convolutional" networks that take input of arbitrary size and produce correspondingly-sized output with efficient inference and learning. We define and detail the space of fully convolutional networks, explain their application to spatially dense prediction tasks, and draw connections to prior models. We adapt contemporary classification networks (AlexNet, the VGG net, and GoogLeNet) into fully convolutional networks and transfer their learned representations by fine-tuning to the segmentation task. We then define a novel architecture that combines semantic information from a deep, coarse layer with appearance information from a shallow, fine layer to produce accurate and detailed segmentations. Our fully convolutional network achieves state-of-the-art segmentation of PASCAL VOC (20% relative improvement to 62.2% mean IU on 2012), NYUDv2, and SIFT Flow, while inference takes one third of a second for a typical image.
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