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The world is going through a challenging phase due to the disastrous effect caused by the COVID-19 pandemic on the healthcare system and the economy. The rate of spreading, post-COVID-19 symptoms, and the occurrence of new strands of COVID-19 have put the healthcare systems in disruption across the globe. Due to this, the task of accurately screening COVID-19 cases has become of utmost priority. Since the virus infects the respiratory system, Chest X-Ray is an imaging modality that is adopted extensively for the initial screening. We have performed a comprehensive study that uses CXR images to identify COVID-19 cases and realized the necessity of having a more generalizable model. We utilize MobileNetV2 architecture as the feature extractor and integrate it into Capsule Networks to construct a fully automated and lightweight model termed as MobileCaps. MobileCaps is trained and evaluated on the publicly available dataset with the model ensembling and Bayesian optimization strategies to efficiently classify CXR images of patients with COVID-19 from non-COVID-19 pneumonia and healthy cases. The proposed model is further evaluated on two additional RT-PCR confirmed datasets to demonstrate the generalizability. We also introduce MobileCaps-S and leverage it for performing severity assessment of CXR images of COVID-19 based on the Radiographic Assessment of Lung Edema (RALE) scoring technique. Our classification model achieved an overall recall of 91.60, 94.60, 92.20, and a precision of 98.50, 88.21, 92.62 for COVID-19, non-COVID-19 pneumonia, and healthy cases, respectively. Further, the severity assessment model attained an R$^2$ coefficient of 70.51. Owing to the fact that the proposed models have fewer trainable parameters than the state-of-the-art models reported in the literature, we believe our models will go a long way in aiding healthcare systems in the battle against the pandemic.

This paper introduces a new type of nonmagnetic actuator for MRI interventions. Ultrasonic and piezoelectric motors are one the most commonly used actuators in MRI applications. However, most of these actuators are only MRI-safe, which means they cannot be operated while imaging as they cause significant visual artifacts. To cope with this issue, we developed a new pneumatic rotary servo-motor (based on the Tesla turbine) that can be effectively used during continuous MR imaging. We thoroughly tested the performance and magnetic properties of our MRI-compatible actuator with several experiments, both inside and outside an MRI scanner. The reported results confirm the feasibility to use this motor for MRI-guided robotic interventions.

Fluid flow simulation is a highly active area with applications in a wide range of engineering problems and interactive systems. Meshless methods like the Moving Particle Semi-implicit (MPS) are a great alternative to deal efficiently with large deformations and free-surface flow. However, mesh-based approaches can achieve higher numerical precision than particle-based techniques with a performance cost. This paper presents a numerically stable and parallelized system that benefits from advances in the literature and parallel computing to obtain an adaptable MPS method. The proposed technique can simulate liquids using different approaches, such as two ways to calculate the particles' pressure, turbulent flow, and multiphase interaction. The method is evaluated under traditional test cases presenting comparable results to recent techniques. This work integrates the previously mentioned advances into a single solution, which can switch on improvements, such as better momentum conservation and less spurious pressure oscillations, through a graphical interface. The code is entirely open-source under the GPLv3 free software license. The GPU-accelerated code reached speedups ranging from 3 to 43 times, depending on the total number of particles. The simulation runs at one fps for a case with approximately 200,000 particles. Code: //github.com/andreluizbvs/VoxarMPS

Although LEGO sets have entertained generations of children and adults, the challenge of designing customized builds matching the complexity of real-world or imagined scenes remains too great for the average enthusiast. In order to make this feat possible, we implement a system that generates a LEGO brick model from 2D images. We design a novel solution to this problem that uses an octree-structured autoencoder trained on 3D voxelized models to obtain a feasible latent representation for model reconstruction, and a separate network trained to predict this latent representation from 2D images. LEGO models are obtained by algorithmic conversion of the 3D voxelized model to bricks. We demonstrate first-of-its-kind conversion of photographs to 3D LEGO models. An octree architecture enables the flexibility to produce multiple resolutions to best fit a user's creative vision or design needs. In order to demonstrate the broad applicability of our system, we generate step-by-step building instructions and animations for LEGO models of objects and human faces. Finally, we test these automatically generated LEGO sets by constructing physical builds using real LEGO bricks.

In recent years Deep Learning has brought about a breakthrough in Medical Image Segmentation. U-Net is the most prominent deep network in this regard, which has been the most popular architecture in the medical imaging community. Despite outstanding overall performance in segmenting multimodal medical images, from extensive experimentations on challenging datasets, we found out that the classical U-Net architecture seems to be lacking in certain aspects. Therefore, we propose some modifications to improve upon the already state-of-the-art U-Net model. Hence, following the modifications we develop a novel architecture MultiResUNet as the potential successor to the successful U-Net architecture. We have compared our proposed architecture MultiResUNet with the classical U-Net on a vast repertoire of multimodal medical images. Albeit slight improvements in the cases of ideal images, a remarkable gain in performance has been attained for challenging images. We have evaluated our model on five different datasets, each with their own unique challenges, and have obtained a relative improvement in performance of 10.15%, 5.07%, 2.63%, 1.41%, and 0.62% respectively.

It is becoming increasingly easy to automatically replace a face of one person in a video with the face of another person by using a pre-trained generative adversarial network (GAN). Recent public scandals, e.g., the faces of celebrities being swapped onto pornographic videos, call for automated ways to detect these Deepfake videos. To help developing such methods, in this paper, we present the first publicly available set of Deepfake videos generated from videos of VidTIMIT database. We used open source software based on GANs to create the Deepfakes, and we emphasize that training and blending parameters can significantly impact the quality of the resulted videos. To demonstrate this impact, we generated videos with low and high visual quality (320 videos each) using differently tuned parameter sets. We showed that the state of the art face recognition systems based on VGG and Facenet neural networks are vulnerable to Deepfake videos, with 85.62% and 95.00% false acceptance rates respectively, which means methods for detecting Deepfake videos are necessary. By considering several baseline approaches, we found that audio-visual approach based on lip-sync inconsistency detection was not able to distinguish Deepfake videos. The best performing method, which is based on visual quality metrics and is often used in presentation attack detection domain, resulted in 8.97% equal error rate on high quality Deepfakes. Our experiments demonstrate that GAN-generated Deepfake videos are challenging for both face recognition systems and existing detection methods, and the further development of face swapping technology will make it even more so.

This work presents a region-growing image segmentation approach based on superpixel decomposition. From an initial contour-constrained over-segmentation of the input image, the image segmentation is achieved by iteratively merging similar superpixels into regions. This approach raises two key issues: (1) how to compute the similarity between superpixels in order to perform accurate merging and (2) in which order those superpixels must be merged together. In this perspective, we firstly introduce a robust adaptive multi-scale superpixel similarity in which region comparisons are made both at content and common border level. Secondly, we propose a global merging strategy to efficiently guide the region merging process. Such strategy uses an adpative merging criterion to ensure that best region aggregations are given highest priorities. This allows to reach a final segmentation into consistent regions with strong boundary adherence. We perform experiments on the BSDS500 image dataset to highlight to which extent our method compares favorably against other well-known image segmentation algorithms. The obtained results demonstrate the promising potential of the proposed approach.

Limited capture range, and the requirement to provide high quality initialization for optimization-based 2D/3D image registration methods, can significantly degrade the performance of 3D image reconstruction and motion compensation pipelines. Challenging clinical imaging scenarios, which contain significant subject motion such as fetal in-utero imaging, complicate the 3D image and volume reconstruction process. In this paper we present a learning based image registration method capable of predicting 3D rigid transformations of arbitrarily oriented 2D image slices, with respect to a learned canonical atlas co-ordinate system. Only image slice intensity information is used to perform registration and canonical alignment, no spatial transform initialization is required. To find image transformations we utilize a Convolutional Neural Network (CNN) architecture to learn the regression function capable of mapping 2D image slices to a 3D canonical atlas space. We extensively evaluate the effectiveness of our approach quantitatively on simulated Magnetic Resonance Imaging (MRI), fetal brain imagery with synthetic motion and further demonstrate qualitative results on real fetal MRI data where our method is integrated into a full reconstruction and motion compensation pipeline. Our learning based registration achieves an average spatial prediction error of 7 mm on simulated data and produces qualitatively improved reconstructions for heavily moving fetuses with gestational ages of approximately 20 weeks. Our model provides a general and computationally efficient solution to the 2D/3D registration initialization problem and is suitable for real-time scenarios.

Image segmentation is still an open problem especially when intensities of the interested objects are overlapped due to the presence of intensity inhomogeneity (also known as bias field). To segment images with intensity inhomogeneities, a bias correction embedded level set model is proposed where Inhomogeneities are Estimated by Orthogonal Primary Functions (IEOPF). In the proposed model, the smoothly varying bias is estimated by a linear combination of a given set of orthogonal primary functions. An inhomogeneous intensity clustering energy is then defined and membership functions of the clusters described by the level set function are introduced to rewrite the energy as a data term of the proposed model. Similar to popular level set methods, a regularization term and an arc length term are also included to regularize and smooth the level set function, respectively. The proposed model is then extended to multichannel and multiphase patterns to segment colourful images and images with multiple objects, respectively. It has been extensively tested on both synthetic and real images that are widely used in the literature and public BrainWeb and IBSR datasets. Experimental results and comparison with state-of-the-art methods demonstrate that advantages of the proposed model in terms of bias correction and segmentation accuracy.

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for 6-month infant brain, due to the poor image quality, among other difficulties inherent to infant brain MRI, e.g., the isointense contrast between white and gray matter and the severe partial volume effect due to small brain sizes. This study investigates the problem with an ensemble of semi-dense fully convolutional neural networks (CNNs), which employs T1-weighted and T2-weighted MR images as input. We demonstrate that the ensemble agreement is highly correlated with the segmentation errors. Therefore, our method provides measures that can guide local user corrections. To the best of our knowledge, this work is the first ensemble of 3D CNNs for suggesting annotations within images. Furthermore, inspired by the very recent success of dense networks, we propose a novel architecture, SemiDenseNet, which connects all convolutional layers directly to the end of the network. Our architecture allows the efficient propagation of gradients during training, while limiting the number of parameters, requiring one order of magnitude less parameters than popular medical image segmentation networks such as 3D U-Net. Another contribution of our work is the study of the impact that early or late fusions of multiple image modalities might have on the performances of deep architectures. We report evaluations of our method on the public data of the MICCAI iSEG-2017 Challenge on 6-month infant brain MRI segmentation, and show very competitive results among 21 teams, ranking first or second in most metrics.