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Federated learning (FL) is an active area of research. One of the most suitable areas for adopting FL is the medical domain, where patient privacy must be respected. Previous research, however, does not provide a practical guide to applying FL in the medical domain. We propose empirical benchmarks and experimental settings for three representative medical datasets with different modalities: longitudinal electronic health records, skin cancer images, and electrocardiogram signals. The likely users of FL such as medical institutions and IT companies can take these benchmarks as guides for adopting FL and minimize their trial and error. For each dataset, each client data is from a different source to preserve real-world heterogeneity. We evaluate six FL algorithms designed for addressing data heterogeneity among clients, and a hybrid algorithm combining the strengths of two representative FL algorithms. Based on experiment results from three modalities, we discover that simple FL algorithms tend to outperform more sophisticated ones, while the hybrid algorithm consistently shows good, if not the best performance. We also find that a frequent global model update leads to better performance under a fixed training iteration budget. As the number of participating clients increases, higher cost is incurred due to increased IT administrators and GPUs, but the performance consistently increases. We expect future users will refer to these empirical benchmarks to design the FL experiments in the medical domain considering their clinical tasks and obtain stronger performance with lower costs.

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Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and self-supervised learning, promise a more universal approach that can be applied flexibly across these diverse conditions. To measure and drive progress in this direction, we present BenchMD: a benchmark that tests how well unified, modality-agnostic methods, including architectures and training techniques (e.g. self-supervised learning, ImageNet pretraining),perform on a diverse array of clinically-relevant medical tasks. BenchMD combines 19 publicly available datasets for 7 medical modalities, including 1D sensor data, 2D images, and 3D volumetric scans. Our benchmark reflects real-world data constraints by evaluating methods across a range of dataset sizes, including challenging few-shot settings that incentivize the use of pretraining. Finally, we evaluate performance on out-of-distribution data collected at different hospitals than the training data, representing naturally-occurring distribution shifts that frequently degrade the performance of medical AI models. Our baseline results demonstrate that no unified learning technique achieves strong performance across all modalities, leaving ample room for improvement on the benchmark. Code is released at //github.com/rajpurkarlab/BenchMD.

Although data-driven methods usually have noticeable performance on disease diagnosis and treatment, they are suspected of leakage of privacy due to collecting data for model training. Recently, federated learning provides a secure and trustable alternative to collaboratively train model without any exchange of medical data among multiple institutes. Therefore, it has draw much attention due to its natural merit on privacy protection. However, when heterogenous medical data exists between different hospitals, federated learning usually has to face with degradation of performance. In the paper, we propose a new personalized framework of federated learning to handle the problem. It successfully yields personalized models based on awareness of similarity between local data, and achieves better tradeoff between generalization and personalization than existing methods. After that, we further design a differentially sparse regularizer to improve communication efficiency during procedure of model training. Additionally, we propose an effective method to reduce the computational cost, which improves computation efficiency significantly. Furthermore, we collect 5 real medical datasets, including 2 public medical image datasets and 3 private multi-center clinical diagnosis datasets, and evaluate its performance by conducting nodule classification, tumor segmentation, and clinical risk prediction tasks. Comparing with 13 existing related methods, the proposed method successfully achieves the best model performance, and meanwhile up to 60% improvement of communication efficiency. Source code is public, and can be accessed at: //github.com/ApplicationTechnologyOfMedicalBigData/pFedNet-code.

Most existing federated learning algorithms are based on the vanilla FedAvg scheme. However, with the increase of data complexity and the number of model parameters, the amount of communication traffic and the number of iteration rounds for training such algorithms increases significantly, especially in non-independently and homogeneously distributed scenarios, where they do not achieve satisfactory performance. In this work, we propose FedND: federated learning with noise distillation. The main idea is to use knowledge distillation to optimize the model training process. In the client, we propose a self-distillation method to train the local model. In the server, we generate noisy samples for each client and use them to distill other clients. Finally, the global model is obtained by the aggregation of local models. Experimental results show that the algorithm achieves the best performance and is more communication-efficient than state-of-the-art methods.

Federated learning (FL) has been a hot topic in recent years. Ever since it was introduced, researchers have endeavored to devise FL systems that protect privacy or ensure fair results, with most research focusing on one or the other. As two crucial ethical notions, the interactions between privacy and fairness are comparatively less studied. However, since privacy and fairness compete, considering each in isolation will inevitably come at the cost of the other. To provide a broad view of these two critical topics, we presented a detailed literature review of privacy and fairness issues, highlighting unique challenges posed by FL and solutions in federated settings. We further systematically surveyed different interactions between privacy and fairness, trying to reveal how privacy and fairness could affect each other and point out new research directions in fair and private FL.

This study aims to compare multiple deep learning-based forecasters for the task of predicting volatility using multivariate data. The paper evaluates a range of models, starting from simpler and shallower ones and progressing to deeper and more complex architectures. Additionally, the performance of these models is compared against naive predictions and variations of classical GARCH models. The prediction of volatility for five assets, namely S&P500, NASDAQ100, gold, silver, and oil, is specifically addressed using GARCH models, Multi-Layer Perceptrons, Recurrent Neural Networks, Temporal Convolutional Networks, and the Temporal Fusion Transformer. In the majority of cases, the Temporal Fusion Transformer, followed by variants of the Temporal Convolutional Network, outperformed classical approaches and shallow networks. These experiments were repeated, and the differences observed between the competing models were found to be statistically significant, thus providing strong encouragement for their practical application.

Generative Adversarial Networks (GANs) are powerful models able to synthesize data samples closely resembling the distribution of real data, yet the diversity of those generated samples is limited due to the so-called mode collapse phenomenon observed in GANs. Especially prone to mode collapse are conditional GANs, which tend to ignore the input noise vector and focus on the conditional information. Recent methods proposed to mitigate this limitation increase the diversity of generated samples, yet they reduce the performance of the models when similarity of samples is required. To address this shortcoming, we propose a novel method to selectively increase the diversity of GAN-generated samples. By adding a simple, yet effective regularization to the training loss function we encourage the generator to discover new data modes for inputs related to diverse outputs while generating consistent samples for the remaining ones. More precisely, we maximise the ratio of distances between generated images and input latent vectors scaling the effect according to the diversity of samples for a given conditional input. We show the superiority of our method in a synthetic benchmark as well as a real-life scenario of simulating data from the Zero Degree Calorimeter of ALICE experiment in LHC, CERN.

Federated Learning (FL) enables multiple clients to collaboratively learn a machine learning model without exchanging their own local data. In this way, the server can exploit the computational power of all clients and train the model on a larger set of data samples among all clients. Although such a mechanism is proven to be effective in various fields, existing works generally assume that each client preserves sufficient data for training. In practice, however, certain clients may only contain a limited number of samples (i.e., few-shot samples). For example, the available photo data taken by a specific user with a new mobile device is relatively rare. In this scenario, existing FL efforts typically encounter a significant performance drop on these clients. Therefore, it is urgent to develop a few-shot model that can generalize to clients with limited data under the FL scenario. In this paper, we refer to this novel problem as federated few-shot learning. Nevertheless, the problem remains challenging due to two major reasons: the global data variance among clients (i.e., the difference in data distributions among clients) and the local data insufficiency in each client (i.e., the lack of adequate local data for training). To overcome these two challenges, we propose a novel federated few-shot learning framework with two separately updated models and dedicated training strategies to reduce the adverse impact of global data variance and local data insufficiency. Extensive experiments on four prevalent datasets that cover news articles and images validate the effectiveness of our framework compared with the state-of-the-art baselines. Our code is provided at //github.com/SongW-SW/F2L.

Federated learning (FL) has been proposed to protect data privacy and virtually assemble the isolated data silos by cooperatively training models among organizations without breaching privacy and security. However, FL faces heterogeneity from various aspects, including data space, statistical, and system heterogeneity. For example, collaborative organizations without conflict of interest often come from different areas and have heterogeneous data from different feature spaces. Participants may also want to train heterogeneous personalized local models due to non-IID and imbalanced data distribution and various resource-constrained devices. Therefore, heterogeneous FL is proposed to address the problem of heterogeneity in FL. In this survey, we comprehensively investigate the domain of heterogeneous FL in terms of data space, statistical, system, and model heterogeneity. We first give an overview of FL, including its definition and categorization. Then, We propose a precise taxonomy of heterogeneous FL settings for each type of heterogeneity according to the problem setting and learning objective. We also investigate the transfer learning methodologies to tackle the heterogeneity in FL. We further present the applications of heterogeneous FL. Finally, we highlight the challenges and opportunities and envision promising future research directions toward new framework design and trustworthy approaches.

Deep neural networks have achieved remarkable success in computer vision tasks. Existing neural networks mainly operate in the spatial domain with fixed input sizes. For practical applications, images are usually large and have to be downsampled to the predetermined input size of neural networks. Even though the downsampling operations reduce computation and the required communication bandwidth, it removes both redundant and salient information obliviously, which results in accuracy degradation. Inspired by digital signal processing theories, we analyze the spectral bias from the frequency perspective and propose a learning-based frequency selection method to identify the trivial frequency components which can be removed without accuracy loss. The proposed method of learning in the frequency domain leverages identical structures of the well-known neural networks, such as ResNet-50, MobileNetV2, and Mask R-CNN, while accepting the frequency-domain information as the input. Experiment results show that learning in the frequency domain with static channel selection can achieve higher accuracy than the conventional spatial downsampling approach and meanwhile further reduce the input data size. Specifically for ImageNet classification with the same input size, the proposed method achieves 1.41% and 0.66% top-1 accuracy improvements on ResNet-50 and MobileNetV2, respectively. Even with half input size, the proposed method still improves the top-1 accuracy on ResNet-50 by 1%. In addition, we observe a 0.8% average precision improvement on Mask R-CNN for instance segmentation on the COCO dataset.

We study the problem of named entity recognition (NER) from electronic medical records, which is one of the most fundamental and critical problems for medical text mining. Medical records which are written by clinicians from different specialties usually contain quite different terminologies and writing styles. The difference of specialties and the cost of human annotation makes it particularly difficult to train a universal medical NER system. In this paper, we propose a label-aware double transfer learning framework (La-DTL) for cross-specialty NER, so that a medical NER system designed for one specialty could be conveniently applied to another one with minimal annotation efforts. The transferability is guaranteed by two components: (i) we propose label-aware MMD for feature representation transfer, and (ii) we perform parameter transfer with a theoretical upper bound which is also label aware. We conduct extensive experiments on 12 cross-specialty NER tasks. The experimental results demonstrate that La-DTL provides consistent accuracy improvement over strong baselines. Besides, the promising experimental results on non-medical NER scenarios indicate that La-DTL is potential to be seamlessly adapted to a wide range of NER tasks.

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