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Although unsupervised domain adaptation methods have achieved remarkable performance in semantic scene segmentation in visual perception for self-driving cars, these approaches remain impractical in real-world use cases. In practice, the segmentation models may encounter new data that have not been seen yet. Also, the previous data training of segmentation models may be inaccessible due to privacy problems. Therefore, to address these problems, in this work, we propose a Continual Unsupervised Domain Adaptation (CONDA) approach that allows the model to continuously learn and adapt with respect to the presence of the new data. Moreover, our proposed approach is designed without the requirement of accessing previous training data. To avoid the catastrophic forgetting problem and maintain the performance of the segmentation models, we present a novel Bijective Maximum Likelihood loss to impose the constraint of predicted segmentation distribution shifts. The experimental results on the benchmark of continual unsupervised domain adaptation have shown the advanced performance of the proposed CONDA method.

Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising treatments have been developed, their effectiveness is low in advanced stages. This emphasizes the importance of large-scale screening programs. Nevertheless, implementing such programs for AMD is usually unfeasible, since the population at risk is large and the diagnosis is challenging. All this motivates the development of automatic methods. In this sense, several works have achieved positive results for AMD diagnosis using convolutional neural networks (CNNs). However, none incorporates explainability mechanisms, which limits their use in clinical practice. In that regard, we propose an explainable deep learning approach for the diagnosis of AMD via the joint identification of its associated retinal lesions. In our proposal, a CNN is trained end-to-end for the joint task using image-level labels. The provided lesion information is of clinical interest, as it allows to assess the developmental stage of AMD. Additionally, the approach allows to explain the diagnosis from the identified lesions. This is possible thanks to the use of a CNN with a custom setting that links the lesions and the diagnosis. Furthermore, the proposed setting also allows to obtain coarse lesion segmentation maps in a weakly-supervised way, further improving the explainability. The training data for the approach can be obtained without much extra work by clinicians. The experiments conducted demonstrate that our approach can identify AMD and its associated lesions satisfactorily, while providing adequate coarse segmentation maps for most common lesions.

Vision-Centric Bird-Eye-View (BEV) perception has shown promising potential and attracted increasing attention in autonomous driving. Recent works mainly focus on improving efficiency or accuracy but neglect the domain shift problem, resulting in severe degradation of transfer performance. With extensive observations, we figure out the significant domain gaps existing in the scene, weather, and day-night changing scenarios and make the first attempt to solve the domain adaption problem for multi-view 3D object detection. Since BEV perception approaches are usually complicated and contain several components, the domain shift accumulation on multi-latent spaces makes BEV domain adaptation challenging. In this paper, we propose a novel Multi-level Multi-space Alignment Teacher-Student ($M^{2}ATS$) framework to ease the domain shift accumulation, which consists of a Depth-Aware Teacher (DAT) and a Multi-space Feature Aligned (MFA) student model. Specifically, DAT model adopts uncertainty guidance to sample reliable depth information in target domain. After constructing domain-invariant BEV perception, it then transfers pixel and instance-level knowledge to student model. To further alleviate the domain shift at the global level, MFA student model is introduced to align task-relevant multi-space features of two domains. To verify the effectiveness of $M^{2}ATS$, we conduct BEV 3D object detection experiments on four cross domain scenarios and achieve state-of-the-art performance (e.g., +12.6% NDS and +9.1% mAP on Day-Night). Code and dataset will be released.

Deep metric learning aims to learn an embedding space, where semantically similar samples are close together and dissimilar ones are repelled against. To explore more hard and informative training signals for augmentation and generalization, recent methods focus on generating synthetic samples to boost metric learning losses. However, these methods just use the deterministic and class-independent generations (e.g., simple linear interpolation), which only can cover the limited part of distribution spaces around original samples. They have overlooked the wide characteristic changes of different classes and can not model abundant intra-class variations for generations. Therefore, generated samples not only lack rich semantics within the certain class, but also might be noisy signals to disturb training. In this paper, we propose a novel intra-class adaptive augmentation (IAA) framework for deep metric learning. We reasonably estimate intra-class variations for every class and generate adaptive synthetic samples to support hard samples mining and boost metric learning losses. Further, for most datasets that have a few samples within the class, we propose the neighbor correction to revise the inaccurate estimations, according to our correlation discovery where similar classes generally have similar variation distributions. Extensive experiments on five benchmarks show our method significantly improves and outperforms the state-of-the-art methods on retrieval performances by 3%-6%. Our code is available at //github.com/darkpromise98/IAA

Transformers have dominated the field of natural language processing, and recently impacted the computer vision area. In the field of medical image analysis, Transformers have also been successfully applied to full-stack clinical applications, including image synthesis/reconstruction, registration, segmentation, detection, and diagnosis. Our paper presents both a position paper and a primer, promoting awareness and application of Transformers in the field of medical image analysis. Specifically, we first overview the core concepts of the attention mechanism built into Transformers and other basic components. Second, we give a new taxonomy of various Transformer architectures tailored for medical image applications and discuss their limitations. Within this review, we investigate key challenges revolving around the use of Transformers in different learning paradigms, improving the model efficiency, and their coupling with other techniques. We hope this review can give a comprehensive picture of Transformers to the readers in the field of medical image analysis.

Recently, contrastive learning (CL) has emerged as a successful method for unsupervised graph representation learning. Most graph CL methods first perform stochastic augmentation on the input graph to obtain two graph views and maximize the agreement of representations in the two views. Despite the prosperous development of graph CL methods, the design of graph augmentation schemes -- a crucial component in CL -- remains rarely explored. We argue that the data augmentation schemes should preserve intrinsic structures and attributes of graphs, which will force the model to learn representations that are insensitive to perturbation on unimportant nodes and edges. However, most existing methods adopt uniform data augmentation schemes, like uniformly dropping edges and uniformly shuffling features, leading to suboptimal performance. In this paper, we propose a novel graph contrastive representation learning method with adaptive augmentation that incorporates various priors for topological and semantic aspects of the graph. Specifically, on the topology level, we design augmentation schemes based on node centrality measures to highlight important connective structures. On the node attribute level, we corrupt node features by adding more noise to unimportant node features, to enforce the model to recognize underlying semantic information. We perform extensive experiments of node classification on a variety of real-world datasets. Experimental results demonstrate that our proposed method consistently outperforms existing state-of-the-art baselines and even surpasses some supervised counterparts, which validates the effectiveness of the proposed contrastive framework with adaptive augmentation.

This paper focuses on the expected difference in borrower's repayment when there is a change in the lender's credit decisions. Classical estimators overlook the confounding effects and hence the estimation error can be magnificent. As such, we propose another approach to construct the estimators such that the error can be greatly reduced. The proposed estimators are shown to be unbiased, consistent, and robust through a combination of theoretical analysis and numerical testing. Moreover, we compare the power of estimating the causal quantities between the classical estimators and the proposed estimators. The comparison is tested across a wide range of models, including linear regression models, tree-based models, and neural network-based models, under different simulated datasets that exhibit different levels of causality, different degrees of nonlinearity, and different distributional properties. Most importantly, we apply our approaches to a large observational dataset provided by a global technology firm that operates in both the e-commerce and the lending business. We find that the relative reduction of estimation error is strikingly substantial if the causal effects are accounted for correctly.

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to pre-train a neural network with unlabeled data, followed by fine-tuning for a downstream task with limited annotations. Contrastive learning, a particular variant of SSL, is a powerful technique for learning image-level representations. In this work, we propose strategies for extending the contrastive learning framework for segmentation of volumetric medical images in the semi-supervised setting with limited annotations, by leveraging domain-specific and problem-specific cues. Specifically, we propose (1) novel contrasting strategies that leverage structural similarity across volumetric medical images (domain-specific cue) and (2) a local version of the contrastive loss to learn distinctive representations of local regions that are useful for per-pixel segmentation (problem-specific cue). We carry out an extensive evaluation on three Magnetic Resonance Imaging (MRI) datasets. In the limited annotation setting, the proposed method yields substantial improvements compared to other self-supervision and semi-supervised learning techniques. When combined with a simple data augmentation technique, the proposed method reaches within 8% of benchmark performance using only two labeled MRI volumes for training, corresponding to only 4% (for ACDC) of the training data used to train the benchmark.

Deep Convolutional Neural Networks have pushed the state-of-the art for semantic segmentation provided that a large amount of images together with pixel-wise annotations is available. Data collection is expensive and a solution to alleviate it is to use transfer learning. This reduces the amount of annotated data required for the network training but it does not get rid of this heavy processing step. We propose a method of transfer learning without annotations on the target task for datasets with redundant content and distinct pixel distributions. Our method takes advantage of the approximate content alignment of the images between two datasets when the approximation error prevents the reuse of annotation from one dataset to another. Given the annotations for only one dataset, we train a first network in a supervised manner. This network autonomously learns to generate deep data representations relevant to the semantic segmentation. Then the images in the new dataset, we train a new network to generate a deep data representation that matches the one from the first network on the previous dataset. The training consists in a regression between feature maps and does not require any annotations on the new dataset. We show that this method reaches performances similar to a classic transfer learning on the PASCAL VOC dataset with synthetic transformations.

This paper reviews recent studies in understanding neural-network representations and learning neural networks with interpretable/disentangled middle-layer representations. Although deep neural networks have exhibited superior performance in various tasks, the interpretability is always the Achilles' heel of deep neural networks. At present, deep neural networks obtain high discrimination power at the cost of low interpretability of their black-box representations. We believe that high model interpretability may help people to break several bottlenecks of deep learning, e.g., learning from very few annotations, learning via human-computer communications at the semantic level, and semantically debugging network representations. We focus on convolutional neural networks (CNNs), and we revisit the visualization of CNN representations, methods of diagnosing representations of pre-trained CNNs, approaches for disentangling pre-trained CNN representations, learning of CNNs with disentangled representations, and middle-to-end learning based on model interpretability. Finally, we discuss prospective trends in explainable artificial intelligence.