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Comparative diagnostic in brain tumor evaluation makes possible to use the available information of a medical center to compare similar cases when a new patient is evaluated. By leveraging Artificial Intelligence models, the proposed system is able of retrieving the most similar cases of brain tumors for a given query. The primary objective is to enhance the diagnostic process by generating more accurate representations of medical images, with a particular focus on patient-specific normal features and pathologies. The proposed model uses Artificial Intelligence to detect patient features to recommend the most similar cases from a database. The system not only suggests similar cases but also balances the representation of healthy and abnormal features in its design. This not only encourages the generalization of its use but also aids clinicians in their decision-making processes. We conducted a comparative analysis of our approach in relation to similar studies. The proposed architecture obtains a Dice coefficient of 0.474 in both tumoral and healthy regions of the patients, which outperforms previous literature. Our proposed model excels at extracting and combining anatomical and pathological features from brain \glspl{mr}, achieving state-of-the-art results while relying on less expensive label information. This substantially reduces the overall cost of the training process. This paper provides substantial grounds for further exploration of the broader applicability and optimization of the proposed architecture to enhance clinical decision-making. The novel approach presented in this work marks a significant advancement in the field of medical diagnosis, particularly in the context of Artificial Intelligence-assisted image retrieval, and promises to reduce costs and improve the quality of patient care using Artificial Intelligence as a support tool instead of a black box system.

The integration of technology into exercise regimens has emerged as a strategy to enhance normal human capabilities and return human motor function after injury or illness by enhancing motor learning and retention. Much research has focused on how active devices, whether confined to a lab or made into a wearable format, can apply forces at set times and conditions to optimize the process of learning. However, the focus on active force production often forces devices to either be confined to simple movements or interventions. As such, in this paper, we investigate how passive device behaviors can contribute to the process of motor learning by themselves. Our approach involves using a wearable resistance (WR) device, which is outfitted with elastic bands, to apply a force field that changes in response to a person's movements while performing exercises. We develop a method to measure the produced forces from the device without impeding the function and we characterize the device's force generation abilities. We then present a study assessing the impact of the WR device on motor learning of proper squat form compared to visual or no feedback. Biometrics such as knee and hip angles were used to monitor and assess subject performance. Our findings indicate that the force fields produced while training with the WR device can improve performance in full-body exercises similarly to a more direct visual feedback mechanism, though the improvement is not consistent across all performance metrics. Through our research, we contribute important insights into the application of passive wearable resistance technology in practical exercise settings.

In the expanding field of language model applications, medical knowledge representation remains a significant challenge due to the specialized nature of the domain. Large language models, such as GPT-4, obtain reasonable scores on medical question answering tasks, but smaller models are far behind. In this work, we introduce a method to improve the proficiency of a small language model in the medical domain by employing a two-fold approach. We first fine-tune the model on a corpus of medical textbooks. Then, we use GPT-4 to generate questions similar to the downstream task, prompted with textbook knowledge, and use them to fine-tune the model. Additionally, we introduce ECN-QA, a novel medical question answering dataset containing ``progressive questions'' composed of related sequential questions. We show the benefits of our training strategy on this dataset. The study's findings highlight the potential of small language models in the medical domain when appropriately fine-tuned. The code and weights are available at //github.com/raidium-med/MQG.

Despite the recent progress in medical image segmentation with scribble-based annotations, the segmentation results of most models are still not ro-bust and generalizable enough in open environments. Evidential deep learn-ing (EDL) has recently been proposed as a promising solution to model predictive uncertainty and improve the reliability of medical image segmen-tation. However directly applying EDL to scribble-supervised medical im-age segmentation faces a tradeoff between accuracy and reliability. To ad-dress the challenge, we propose a novel framework called Dual-Branch Evi-dential Deep Learning (DuEDL). Firstly, the decoder of the segmentation network is changed to two different branches, and the evidence of the two branches is fused to generate high-quality pseudo-labels. Then the frame-work applies partial evidence loss and two-branch consistent loss for joint training of the model to adapt to the scribble supervision learning. The pro-posed method was tested on two cardiac datasets: ACDC and MSCMRseg. The results show that our method significantly enhances the reliability and generalization ability of the model without sacrificing accuracy, outper-forming state-of-the-art baselines. The code is available at //github.com/Gardnery/DuEDL.

The purpose of this study is to estimate the correlation structure between multiple assets using financial text analysis. In recent years, as the background of elevating inflation in the global economy and monetary policy tightening by central banks, the correlation structure between assets, especially interest rate sensitivity and inflation sensitivity, has changed dramatically, increasing the impact on the performance of investors' portfolios. Therefore, the importance of estimating a robust correlation structure in portfolio management has increased. On the other hand, the correlation coefficient using only the historical price data observed in the financial market is accompanied by a certain degree of time lag, and also has the aspect that prediction errors can occur due to the nonstationarity of financial time series data, and that the interpretability from the viewpoint of fundamentals is a little poor when a phase change occurs. In this study, we performed natural language processing on news text and central bank text to verify the prediction accuracy of future correlation coefficient changes. As a result, it was suggested that this method is useful in comparison with the prediction from ordinary time series data.

Eating disorders (ED), a severe mental health condition with high rates of mortality and morbidity, affect millions of people globally, especially adolescents. The proliferation of online communities that promote and normalize ED has been linked to this public health crisis. However, identifying harmful communities is challenging due to the use of coded language and other obfuscations. To address this challenge, we propose a novel framework to surface implicit attitudes of online communities by adapting large language models (LLMs) to the language of the community. We describe an alignment method and evaluate results along multiple dimensions of semantics and affect. We then use the community-aligned LLM to respond to psychometric questionnaires designed to identify ED in individuals. We demonstrate that LLMs can effectively adopt community-specific perspectives and reveal significant variations in eating disorder risks in different online communities. These findings highlight the utility of LLMs to reveal implicit attitudes and collective mindsets of communities, offering new tools for mitigating harmful content on social media.

We describe ACE0, a lightweight platform for evaluating the suitability and viability of AI methods for behaviour discovery in multiagent simulations. Specifically, ACE0 was designed to explore AI methods for multi-agent simulations used in operations research studies related to new technologies such as autonomous aircraft. Simulation environments used in production are often high-fidelity, complex, require significant domain knowledge and as a result have high R&D costs. Minimal and lightweight simulation environments can help researchers and engineers evaluate the viability of new AI technologies for behaviour discovery in a more agile and potentially cost effective manner. In this paper we describe the motivation for the development of ACE0.We provide a technical overview of the system architecture, describe a case study of behaviour discovery in the aerospace domain, and provide a qualitative evaluation of the system. The evaluation includes a brief description of collaborative research projects with academic partners, exploring different AI behaviour discovery methods.

Analyzing observational data from multiple sources can be useful for increasing statistical power to detect a treatment effect; however, practical constraints such as privacy considerations may restrict individual-level information sharing across data sets. This paper develops federated methods that only utilize summary-level information from heterogeneous data sets. Our federated methods provide doubly-robust point estimates of treatment effects as well as variance estimates. We derive the asymptotic distributions of our federated estimators, which are shown to be asymptotically equivalent to the corresponding estimators from the combined, individual-level data. We show that to achieve these properties, federated methods should be adjusted based on conditions such as whether models are correctly specified and stable across heterogeneous data sets.

Human doctors with well-structured medical knowledge can diagnose a disease merely via a few conversations with patients about symptoms. In contrast, existing knowledge-grounded dialogue systems often require a large number of dialogue instances to learn as they fail to capture the correlations between different diseases and neglect the diagnostic experience shared among them. To address this issue, we propose a more natural and practical paradigm, i.e., low-resource medical dialogue generation, which can transfer the diagnostic experience from source diseases to target ones with a handful of data for adaptation. It is capitalized on a commonsense knowledge graph to characterize the prior disease-symptom relations. Besides, we develop a Graph-Evolving Meta-Learning (GEML) framework that learns to evolve the commonsense graph for reasoning disease-symptom correlations in a new disease, which effectively alleviates the needs of a large number of dialogues. More importantly, by dynamically evolving disease-symptom graphs, GEML also well addresses the real-world challenges that the disease-symptom correlations of each disease may vary or evolve along with more diagnostic cases. Extensive experiment results on the CMDD dataset and our newly-collected Chunyu dataset testify the superiority of our approach over state-of-the-art approaches. Besides, our GEML can generate an enriched dialogue-sensitive knowledge graph in an online manner, which could benefit other tasks grounded on knowledge graph.

Knowledge graph embedding, which aims to represent entities and relations as low dimensional vectors (or matrices, tensors, etc.), has been shown to be a powerful technique for predicting missing links in knowledge graphs. Existing knowledge graph embedding models mainly focus on modeling relation patterns such as symmetry/antisymmetry, inversion, and composition. However, many existing approaches fail to model semantic hierarchies, which are common in real-world applications. To address this challenge, we propose a novel knowledge graph embedding model---namely, Hierarchy-Aware Knowledge Graph Embedding (HAKE)---which maps entities into the polar coordinate system. HAKE is inspired by the fact that concentric circles in the polar coordinate system can naturally reflect the hierarchy. Specifically, the radial coordinate aims to model entities at different levels of the hierarchy, and entities with smaller radii are expected to be at higher levels; the angular coordinate aims to distinguish entities at the same level of the hierarchy, and these entities are expected to have roughly the same radii but different angles. Experiments demonstrate that HAKE can effectively model the semantic hierarchies in knowledge graphs, and significantly outperforms existing state-of-the-art methods on benchmark datasets for the link prediction task.