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Untargeted metabolomics based on liquid chromatography-mass spectrometry technology is quickly gaining widespread application given its ability to depict the global metabolic pattern in biological samples. However, the data is noisy and plagued by the lack of clear identity of data features measured from samples. Multiple potential matchings exist between data features and known metabolites, while the truth can only be one-to-one matches. Some existing methods attempt to reduce the matching uncertainty, but are far from being able to remove the uncertainty for most features. The existence of the uncertainty causes major difficulty in downstream functional analysis. To address these issues, we develop a novel approach for Bayesian Analysis of Untargeted Metabolomics data (BAUM) to integrate previously separate tasks into a single framework, including matching uncertainty inference, metabolite selection, and functional analysis. By incorporating the knowledge graph between variables and using relatively simple assumptions, BAUM can analyze datasets with small sample sizes. By allowing different confidence levels of feature-metabolite matching, the method is applicable to datasets in which feature identities are partially known. Simulation studies demonstrate that, compared with other existing methods, BAUM achieves better accuracy in selecting important metabolites that tend to be functionally consistent and assigning confidence scores to feature-metabolite matches. We analyze a COVID-19 metabolomics dataset and a mouse brain metabolomics dataset using BAUM. Even with a very small sample size of 16 mice per group, BAUM is robust and stable. It finds pathways that conform to existing knowledge, as well as novel pathways that are biologically plausible.

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High-level synthesis, source-to-source compilers, and various Design Space Exploration techniques for pragma insertion have significantly improved the Quality of Results of generated designs. These tools offer benefits such as reduced development time and enhanced performance. However, achieving high-quality results often requires additional manual code transformations and tiling selections, which are typically performed separately or as pre-processing steps. Although DSE techniques enable code transformation upfront, the vastness of the search space often limits the exploration of all possible code transformations, making it challenging to determine which transformations are necessary. Additionally, ensuring correctness remains challenging, especially for complex transformations and optimizations. To tackle this obstacle, we first propose a comprehensive framework leveraging HLS compilers. Our system streamlines code transformation, pragma insertion, and tiles size selection for on-chip data caching through a unified optimization problem, aiming to enhance parallelization, particularly beneficial for computation-bound kernels. Them employing a novel Non-Linear Programming (NLP) approach, we simultaneously ascertain transformations, pragmas, and tile sizes, focusing on regular loop-based kernels. Our evaluation demonstrates that our framework adeptly identifies the appropriate transformations, including scenarios where no transformation is necessary, and inserts pragmas to achieve a favorable Quality of Results.

While recommender systems with multi-modal item representations (image, audio, and text), have been widely explored, learning recommendations from multi-modal user interactions (e.g., clicks and speech) remains an open problem. We study the case of multi-modal user interactions in a setting where users engage with a service provider through multiple channels (website and call center). In such cases, incomplete modalities naturally occur, since not all users interact through all the available channels. To address these challenges, we publish a real-world dataset that allows progress in this under-researched area. We further present and benchmark various methods for leveraging multi-modal user interactions for item recommendations, and propose a novel approach that specifically deals with missing modalities by mapping user interactions to a common feature space. Our analysis reveals important interactions between the different modalities and that a frequently occurring modality can enhance learning from a less frequent one.

Contemporary recommender systems predominantly rely on collaborative filtering techniques, employing ID-embedding to capture latent associations among users and items. However, this approach overlooks the wealth of semantic information embedded within textual descriptions of items, leading to suboptimal performance in cold-start scenarios and long-tail user recommendations. Leveraging the capabilities of Large Language Models (LLMs) pretrained on massive text corpus presents a promising avenue for enhancing recommender systems by integrating open-world domain knowledge. In this paper, we propose an Llm-driven knowlEdge Adaptive RecommeNdation (LEARN) framework that synergizes open-world knowledge with collaborative knowledge. We address computational complexity concerns by utilizing pretrained LLMs as item encoders and freezing LLM parameters to avoid catastrophic forgetting and preserve open-world knowledge. To bridge the gap between the open-world and collaborative domains, we design a twin-tower structure supervised by the recommendation task and tailored for practical industrial application. Through offline experiments on the large-scale industrial dataset and online experiments on A/B tests, we demonstrate the efficacy of our approach.

With the increased use of data-driven approaches and machine learning-based methods in material science, the importance of reliable uncertainty quantification (UQ) of the predicted variables for informed decision-making cannot be overstated. UQ in material property prediction poses unique challenges, including the multi-scale and multi-physics nature of advanced materials, intricate interactions between numerous factors, limited availability of large curated datasets for model training, etc. Recently, Bayesian Neural Networks (BNNs) have emerged as a promising approach for UQ, offering a probabilistic framework for capturing uncertainties within neural networks. In this work, we introduce an approach for UQ within physics-informed BNNs, which integrates knowledge from governing laws in material modeling to guide the models toward physically consistent predictions. To evaluate the effectiveness of this approach, we present case studies for predicting the creep rupture life of steel alloys. Experimental validation with three datasets of collected measurements from creep tests demonstrates the ability of BNNs to produce accurate point and uncertainty estimates that are competitive or exceed the performance of the conventional method of Gaussian Process Regression. Similarly, we evaluated the suitability of BNNs for UQ in an active learning application and reported competitive performance. The most promising framework for creep life prediction is BNNs based on Markov Chain Monte Carlo approximation of the posterior distribution of network parameters, as it provided more reliable results in comparison to BNNs based on variational inference approximation or related NNs with probabilistic outputs. The codes are available at: //github.com/avakanski/Creep-uncertainty-quantification.

Matrix-vector multiplication forms the basis of many iterative solution algorithms and as such is an important algorithm also for hierarchical matrices. However, due to its low computational intensity, its performance is typically limited by the available memory bandwidth. By optimizing the storage representation of the data within such matrices, this limitation can be lifted and the performance increased. This applies not only to hierarchical matrices but for also for other low-rank approximation schemes, e.g. block low-rank matrices.

By concatenating a polar transform with a convolutional transform, polarization-adjusted convolutional (PAC) codes can reach the dispersion approximation bound in certain rate cases. However, the sequential decoding nature of traditional PAC decoding algorithms results in high decoding latency. Due to the parallel computing capability, deep neural network (DNN) decoders have emerged as a promising solution. In this paper, we propose three types of DNN decoders for PAC codes: multi-layer perceptron (MLP), convolutional neural network (CNN), and recurrent neural network (RNN). The performance of these DNN decoders is evaluated through extensive simulation. Numerical results show that the MLP decoder has the best error-correction performance under a similar model parameter number.

In the context of the Internet of Things (IoT), reliable and energy-efficient provision of IoT applications has become critical. Equipping IoT systems with tools that enable a flexible, well-performing, and automated way of monitoring and managing IoT edge devices is an essential prerequisite. In current IoT systems, low-power edge appliances have been utilized in a way that can not be controlled and re-configured in a timely manner. Hence, conducting a trade-off solution between manageability, performance and design requirements are demanded. This paper introduces a novel approach for fine-grained monitoring and managing individual micro-services within low-power edge devices, which improves system reliability and energy efficiency. The proposed method enables operational flexibility for IoT edge devices by leveraging a modularization technique. Following a review of existing solutions for remote-managed IoT services, a detailed description of the suggested approach is presented. Also, to explore the essential design principles that must be considered in this approach, the suggested architecture is elaborated in detail. Finally, the advantages of the proposed solution to deal with disruptions are demonstrated in the proof of concept-based experiments.

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution by generating artificial data that mimics real-world patterns. This paper provides an overview of synthetic data research, discussing its applications, challenges, and future directions. We present empirical evidence from prior art to demonstrate its effectiveness and highlight the importance of ensuring its factuality, fidelity, and unbiasedness. We emphasize the need for responsible use of synthetic data to build more powerful, inclusive, and trustworthy language models.

Translational distance-based knowledge graph embedding has shown progressive improvements on the link prediction task, from TransE to the latest state-of-the-art RotatE. However, N-1, 1-N and N-N predictions still remain challenging. In this work, we propose a novel translational distance-based approach for knowledge graph link prediction. The proposed method includes two-folds, first we extend the RotatE from 2D complex domain to high dimension space with orthogonal transforms to model relations for better modeling capacity. Second, the graph context is explicitly modeled via two directed context representations. These context representations are used as part of the distance scoring function to measure the plausibility of the triples during training and inference. The proposed approach effectively improves prediction accuracy on the difficult N-1, 1-N and N-N cases for knowledge graph link prediction task. The experimental results show that it achieves better performance on two benchmark data sets compared to the baseline RotatE, especially on data set (FB15k-237) with many high in-degree connection nodes.

Image segmentation is considered to be one of the critical tasks in hyperspectral remote sensing image processing. Recently, convolutional neural network (CNN) has established itself as a powerful model in segmentation and classification by demonstrating excellent performances. The use of a graphical model such as a conditional random field (CRF) contributes further in capturing contextual information and thus improving the segmentation performance. In this paper, we propose a method to segment hyperspectral images by considering both spectral and spatial information via a combined framework consisting of CNN and CRF. We use multiple spectral cubes to learn deep features using CNN, and then formulate deep CRF with CNN-based unary and pairwise potential functions to effectively extract the semantic correlations between patches consisting of three-dimensional data cubes. Effective piecewise training is applied in order to avoid the computationally expensive iterative CRF inference. Furthermore, we introduce a deep deconvolution network that improves the segmentation masks. We also introduce a new dataset and experimented our proposed method on it along with several widely adopted benchmark datasets to evaluate the effectiveness of our method. By comparing our results with those from several state-of-the-art models, we show the promising potential of our method.

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