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Sensors measuring real-life physical processes are ubiquitous in today's interconnected world. These sensors inherently bear noise that often adversely affects performance and reliability of the systems they support. Classic filtering-based approaches introduce strong assumptions on the time or frequency characteristics of sensory measurements, while learning-based denoising approaches typically rely on using ground truth clean data to train a denoising model, which is often challenging or prohibitive to obtain for many real-world applications. We observe that in many scenarios, the relationships between different sensor measurements (e.g., location and acceleration) are analytically described by laws of physics (e.g., second-order differential equation). By incorporating such physics constraints, we can guide the denoising process to improve even in the absence of ground truth data. In light of this, we design a physics-informed denoising model that leverages the inherent algebraic relationships between different measurements governed by the underlying physics. By obviating the need for ground truth clean data, our method offers a practical denoising solution for real-world applications. We conducted experiments in various domains, including inertial navigation, CO2 monitoring, and HVAC control, and achieved state-of-the-art performance compared with existing denoising methods. Our method can denoise data in real time (4ms for a sequence of 1s) for low-cost noisy sensors and produces results that closely align with those from high-precision, high-cost alternatives, leading to an efficient, cost-effective approach for more accurate sensor-based systems.

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Missingness is ubiquitous in multivariate time series and poses an obstacle to reliable downstream analysis. Although recurrent network imputation achieved the SOTA, existing models do not scale to deep architectures that can potentially alleviate issues arising in complex data. Moreover, imputation carries the risk of biased estimations of the ground truth. Yet, confidence in the imputed values is always unmeasured or computed post hoc from model output. We propose DEep Attention Recurrent Imputation (DEARI), which jointly estimates missing values and their associated uncertainty in heterogeneous multivariate time series. By jointly representing feature-wise correlations and temporal dynamics, we adopt a self attention mechanism, along with an effective residual component, to achieve a deep recurrent neural network with good imputation performance and stable convergence. We also leverage self-supervised metric learning to boost performance by optimizing sample similarity. Finally, we transform DEARI into a Bayesian neural network through a novel Bayesian marginalization strategy to produce stochastic DEARI, which outperforms its deterministic equivalent. Experiments show that DEARI surpasses the SOTA in diverse imputation tasks using real-world datasets, namely air quality control, healthcare and traffic.

RGB-T semantic segmentation is a key technique for autonomous driving scenes understanding. For the existing RGB-T semantic segmentation methods, however, the effective exploration of the complementary relationship between different modalities is not implemented in the information interaction between multiple levels. To address such an issue, the Context-Aware Interaction Network (CAINet) is proposed for RGB-T semantic segmentation, which constructs interaction space to exploit auxiliary tasks and global context for explicitly guided learning. Specifically, we propose a Context-Aware Complementary Reasoning (CACR) module aimed at establishing the complementary relationship between multimodal features with the long-term context in both spatial and channel dimensions. Further, considering the importance of global contextual and detailed information, we propose the Global Context Modeling (GCM) module and Detail Aggregation (DA) module, and we introduce specific auxiliary supervision to explicitly guide the context interaction and refine the segmentation map. Extensive experiments on two benchmark datasets of MFNet and PST900 demonstrate that the proposed CAINet achieves state-of-the-art performance. The code is available at //github.com/YingLv1106/CAINet.

Harnessing the power of human-annotated data through Supervised Fine-Tuning (SFT) is pivotal for advancing Large Language Models (LLMs). In this paper, we delve into the prospect of growing a strong LLM out of a weak one without the need for acquiring additional human-annotated data. We propose a new fine-tuning method called Self-Play fIne-tuNing (SPIN), which starts from a supervised fine-tuned model. At the heart of SPIN lies a self-play mechanism, where the LLM refines its capability by playing against instances of itself. More specifically, the LLM generates its own training data from its previous iterations, refining its policy by discerning these self-generated responses from those obtained from human-annotated data. Our method progressively elevates the LLM from a nascent model to a formidable one, unlocking the full potential of human-annotated demonstration data for SFT. Theoretically, we prove that the global optimum to the training objective function of our method is achieved only when the LLM policy aligns with the target data distribution. Empirically, we evaluate our method on several benchmark datasets including the HuggingFace Open LLM Leaderboard, MT-Bench, and datasets from Big-Bench. Our results show that SPIN can significantly improve the LLM's performance across a variety of benchmarks and even outperform models trained through direct preference optimization (DPO) supplemented with extra GPT-4 preference data. This sheds light on the promise of self-play, enabling the achievement of human-level performance in LLMs without the need for expert opponents.

Our brains extract durable, generalizable knowledge from transient experiences of the world. Artificial neural networks come nowhere close to this ability. When tasked with learning to classify objects by training on non-repeating video frames in temporal order (online stream learning), models that learn well from shuffled datasets catastrophically forget old knowledge upon learning new stimuli. We propose a new continual learning algorithm, Compositional Replay Using Memory Blocks (CRUMB), which mitigates forgetting by replaying feature maps reconstructed by combining generic parts. CRUMB concatenates trainable and re-usable "memory block" vectors to compositionally reconstruct feature map tensors in convolutional neural networks. Storing the indices of memory blocks used to reconstruct new stimuli enables memories of the stimuli to be replayed during later tasks. This reconstruction mechanism also primes the neural network to minimize catastrophic forgetting by biasing it towards attending to information about object shapes more than information about image textures, and stabilizes the network during stream learning by providing a shared feature-level basis for all training examples. These properties allow CRUMB to outperform an otherwise identical algorithm that stores and replays raw images, while occupying only 3.6% as much memory. We stress-tested CRUMB alongside 13 competing methods on 7 challenging datasets. To address the limited number of existing online stream learning datasets, we introduce 2 new benchmarks by adapting existing datasets for stream learning. With only 3.7-4.1% as much memory and 15-43% as much runtime, CRUMB mitigates catastrophic forgetting more effectively than the state-of-the-art. Our code is available at //github.com/MorganBDT/crumb.git.

In robust optimization problems, the magnitude of perturbations is relatively small. Consequently, solutions within certain regions are less likely to represent the robust optima when perturbations are introduced. Hence, a more efficient search process would benefit from increased opportunities to explore promising regions where global optima or good local optima are situated. In this paper, we introduce a novel robust evolutionary algorithm named the dual-stage robust evolutionary algorithm (DREA) aimed at discovering robust solutions. DREA operates in two stages: the peak-detection stage and the robust solution-searching stage. The primary objective of the peak-detection stage is to identify peaks in the fitness landscape of the original optimization problem. Conversely, the robust solution-searching stage focuses on swiftly identifying the robust optimal solution using information obtained from the peaks discovered in the initial stage. These two stages collectively enable the proposed DREA to efficiently obtain the robust optimal solution for the optimization problem. This approach achieves a balance between solution optimality and robustness by separating the search processes for optimal and robust optimal solutions. Experimental results demonstrate that DREA significantly outperforms five state-of-the-art algorithms across 18 test problems characterized by diverse complexities. Moreover, when evaluated on higher-dimensional robust optimization problems (100-$D$ and 200-$D$), DREA also demonstrates superior performance compared to all five counterpart algorithms.

The goal of Continual Learning (CL) is to continuously learn from new data streams and accomplish the corresponding tasks. Previously studied CL assumes that data are given in sequence nose-to-tail for different tasks, thus indeed belonging to Serial Continual Learning (SCL). This paper studies the novel paradigm of Parallel Continual Learning (PCL) in dynamic multi-task scenarios, where a diverse set of tasks is encountered at different time points. PCL presents challenges due to the training of an unspecified number of tasks with varying learning progress, leading to the difficulty of guaranteeing effective model updates for all encountered tasks. In our previous conference work, we focused on measuring and reducing the discrepancy among gradients in a multi-objective optimization problem, which, however, may still contain negative transfers in every model update. To address this issue, in the dynamic multi-objective optimization problem, we introduce task-specific elastic factors to adjust the descent direction towards the Pareto front. The proposed method, called Elastic Multi-Gradient Descent (EMGD), ensures that each update follows an appropriate Pareto descent direction, minimizing any negative impact on previously learned tasks. To balance the training between old and new tasks, we also propose a memory editing mechanism guided by the gradient computed using EMGD. This editing process updates the stored data points, reducing interference in the Pareto descent direction from previous tasks. Experiments on public datasets validate the effectiveness of our EMGD in the PCL setting.

Scientists are adopting new approaches to scale up their activities and goals. Progress in neurotechnologies, artificial intelligence, automation, and tools for collaboration promises new bursts of discoveries. However, compared to other disciplines and the industry, neuroscience laboratories have been slow to adopt key technologies to support collaboration, reproducibility, and automation. Drawing on progress in other fields, we define a roadmap for implementing automated research workflows for diverse research teams. We propose establishing a five-level capability maturity model for operations in neuroscience research. Achieving higher levels of operational maturity requires new technology-enabled methodologies, which we describe as ``SciOps''. The maturity model provides guidelines for evaluating and upgrading operations in multidisciplinary neuroscience teams.

Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to physicians has long been viewed as one such grand challenge. Large language models (LLMs) have catalyzed significant progress in medical question answering; Med-PaLM was the first model to exceed a "passing" score in US Medical Licensing Examination (USMLE) style questions with a score of 67.2% on the MedQA dataset. However, this and other prior work suggested significant room for improvement, especially when models' answers were compared to clinicians' answers. Here we present Med-PaLM 2, which bridges these gaps by leveraging a combination of base LLM improvements (PaLM 2), medical domain finetuning, and prompting strategies including a novel ensemble refinement approach. Med-PaLM 2 scored up to 86.5% on the MedQA dataset, improving upon Med-PaLM by over 19% and setting a new state-of-the-art. We also observed performance approaching or exceeding state-of-the-art across MedMCQA, PubMedQA, and MMLU clinical topics datasets. We performed detailed human evaluations on long-form questions along multiple axes relevant to clinical applications. In pairwise comparative ranking of 1066 consumer medical questions, physicians preferred Med-PaLM 2 answers to those produced by physicians on eight of nine axes pertaining to clinical utility (p < 0.001). We also observed significant improvements compared to Med-PaLM on every evaluation axis (p < 0.001) on newly introduced datasets of 240 long-form "adversarial" questions to probe LLM limitations. While further studies are necessary to validate the efficacy of these models in real-world settings, these results highlight rapid progress towards physician-level performance in medical question answering.

Vast amount of data generated from networks of sensors, wearables, and the Internet of Things (IoT) devices underscores the need for advanced modeling techniques that leverage the spatio-temporal structure of decentralized data due to the need for edge computation and licensing (data access) issues. While federated learning (FL) has emerged as a framework for model training without requiring direct data sharing and exchange, effectively modeling the complex spatio-temporal dependencies to improve forecasting capabilities still remains an open problem. On the other hand, state-of-the-art spatio-temporal forecasting models assume unfettered access to the data, neglecting constraints on data sharing. To bridge this gap, we propose a federated spatio-temporal model -- Cross-Node Federated Graph Neural Network (CNFGNN) -- which explicitly encodes the underlying graph structure using graph neural network (GNN)-based architecture under the constraint of cross-node federated learning, which requires that data in a network of nodes is generated locally on each node and remains decentralized. CNFGNN operates by disentangling the temporal dynamics modeling on devices and spatial dynamics on the server, utilizing alternating optimization to reduce the communication cost, facilitating computations on the edge devices. Experiments on the traffic flow forecasting task show that CNFGNN achieves the best forecasting performance in both transductive and inductive learning settings with no extra computation cost on edge devices, while incurring modest communication cost.

We investigate the problem of automatically determining what type of shoe left an impression found at a crime scene. This recognition problem is made difficult by the variability in types of crime scene evidence (ranging from traces of dust or oil on hard surfaces to impressions made in soil) and the lack of comprehensive databases of shoe outsole tread patterns. We find that mid-level features extracted by pre-trained convolutional neural nets are surprisingly effective descriptors for this specialized domains. However, the choice of similarity measure for matching exemplars to a query image is essential to good performance. For matching multi-channel deep features, we propose the use of multi-channel normalized cross-correlation and analyze its effectiveness. Our proposed metric significantly improves performance in matching crime scene shoeprints to laboratory test impressions. We also show its effectiveness in other cross-domain image retrieval problems: matching facade images to segmentation labels and aerial photos to map images. Finally, we introduce a discriminatively trained variant and fine-tune our system through our proposed metric, obtaining state-of-the-art performance.

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