As the world progresses in technology and health, awareness of disease by revealing asymptomatic signs improves. It is important to detect and treat tumors in early stage as it can be life-threatening. Computer-aided technologies are used to overcome lingering limitations facing disease diagnosis, while brain tumor segmentation remains a difficult process, especially when multi-modality data is involved. This is mainly attributed to ineffective training due to lack of data and corresponding labelling. This work investigates the feasibility of employing deep-fake image generation for effective brain tumor segmentation. To this end, a Generative Adversarial Network was used for image-to-image translation for increasing dataset size, followed by image segmentation using a U-Net-based convolutional neural network trained with deepfake images. Performance of the proposed approach is compared with ground truth of four publicly available datasets. Results show improved performance in terms of image segmentation quality metrics, and could potentially assist when training with limited data.
The openness of modern IT systems and their permanent change make it challenging to keep these systems secure. A combination of regression and security testing called security regression testing, which ensures that changes made to a system do not harm its security, are therefore of high significance and the interest in such approaches has steadily increased. In this article we present a systematic classification of available security regression testing approaches based on a solid study of background and related work to sketch which parts of the research area seem to be well understood and evaluated, and which ones require further research. For this purpose we extract approaches relevant to security regression testing from computer science digital libraries based on a rigorous search and selection strategy. Then, we provide a classification of these according to security regression approach criteria: abstraction level, security issue, regression testing techniques, and tool support, as well as evaluation criteria, for instance evaluated system, maturity of the system, and evaluation measures. From the resulting classification we derive observations with regard to the abstraction level, regression testing techniques, tool support as well as evaluation, and finally identify several potential directions of future research.
Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the broad applications of medical imaging classification driven by DNN with large-scale training data have been largely hindered. For example, when training the DNN from one domain (e.g., with data only from one hospital), the generalization capability to another domain (e.g., data from another hospital) could be largely lacking. In this paper, we aim to tackle this problem by developing the privacy-preserving constrained domain generalization method, aiming to improve the generalization capability under the privacy-preserving condition. In particular, We propose to improve the information aggregation process on the centralized server-side with a novel gradient alignment loss, expecting that the trained model can be better generalized to the "unseen" but related medical images. The rationale and effectiveness of our proposed method can be explained by connecting our proposed method with the Maximum Mean Discrepancy (MMD) which has been widely adopted as the distribution distance measurement. Experimental results on two challenging medical imaging classification tasks indicate that our method can achieve better cross-domain generalization capability compared to the state-of-the-art federated learning methods.
The majority of prior work on information retrieval (IR) assumes that the corpus is static, whereas in the real world, the documents are continually updated. In this paper, we incorporate often overlooked dynamic nature of knowledge into the retrieval systems. Our work treats retrieval not as static archives but as dynamic knowledge bases better aligned with real-world environments. We conduct a comprehensive evaluation of dual encoders and generative retrieval, utilizing the StreamingQA benchmark designed for the temporal knowledge updates. Our initial results show that while generative retrieval outperforms dual encoders in static settings, the opposite is true in dynamic settings. Surprisingly, however, when we utilize a parameter-efficient pre-training method to enhance adaptability of generative retrieval to new corpora, our resulting model, Dynamic Generative Retrieval (DynamicGR), exhibits unexpected findings. It (1) efficiently compresses new knowledge in their internal index, attaining a remarkable storage capacity due to its fully parametric architecture and (2) outperforms dual encoders not only in static settings but in dynamic scenarios with a 5% margin in hit@5, requiring 4 times less training time.
Scarcity of health care resources could result in the unavoidable consequence of rationing. For example, ventilators are often limited in supply, especially during public health emergencies or in resource-constrained health care settings, such as amid the pandemic of COVID-19. Currently, there is no universally accepted standard for health care resource allocation protocols, resulting in different governments prioritizing patients based on various criteria and heuristic-based protocols. In this study, we investigate the use of reinforcement learning for critical care resource allocation policy optimization to fairly and effectively ration resources. We propose a transformer-based deep Q-network to integrate the disease progression of individual patients and the interaction effects among patients during the critical care resource allocation. We aim to improve both fairness of allocation and overall patient outcomes. Our experiments demonstrate that our method significantly reduces excess deaths and achieves a more equitable distribution under different levels of ventilator shortage, when compared to existing severity-based and comorbidity-based methods in use by different governments. Our source code is included in the supplement and will be released on Github upon publication.
Glioma is a prevalent brain tumor that poses a significant health risk to individuals. Accurate segmentation of brain tumor is essential for clinical diagnosis and treatment. The Segment Anything Model(SAM), released by Meta AI, is a fundamental model in image segmentation and has excellent zero-sample generalization capabilities. Thus, it is interesting to apply SAM to the task of brain tumor segmentation. In this study, we evaluated the performance of SAM on brain tumor segmentation and found that without any model fine-tuning, there is still a gap between SAM and the current state-of-the-art(SOTA) model.
Graph algorithms are widely used for decision making and knowledge discovery. To ensure their effectiveness, it is essential that their output remains stable even when subjected to small perturbations to the input because frequent output changes can result in costly decisions, reduced user trust, potential security concerns, and lack of replicability. In this study, we consider the Lipschitz continuity of algorithms as a stability measure and initiate a systematic study of the Lipschitz continuity of algorithms for (weighted) graph problems. Depending on how we embed the output solution to a metric space, we can think of several Lipschitzness notions. We mainly consider the one that is invariant under scaling of weights, and we provide Lipschitz continuous algorithms and lower bounds for the minimum spanning tree problem, the shortest path problem, and the maximum weight matching problem. In particular, our shortest path algorithm is obtained by first designing an algorithm for unweighted graphs that are robust against edge contractions and then applying it to the unweighted graph constructed from the original weighted graph. Then, we consider another Lipschitzness notion induced by a natural mapping that maps the output solution to its characteristic vector. It turns out that no Lipschitz continuous algorithm exists for this Lipschitz notion, and we instead design algorithms with bounded pointwise Lipschitz constants for the minimum spanning tree problem and the maximum weight bipartite matching problem. Our algorithm for the latter problem is based on an LP relaxation with entropy regularization.
AMR is widely used in factories to replace manual labor to reduce costs and improve efficiency. However, it is often difficult for logistics robots to plan the optimal trajectory and unreasonable trajectory planning can lead to low transport efficiency and high energy consumption. In this paper, we propose a method to directly calculate the optimal trajectory for short distance on the basis of the Dubins set, which completes the calculation of the Dubins path. Additionally, as an improvement of Dubins path, we smooth the Dubins path based on clothoid, which makes the curvature varies linearly. AMR can adjust the steering wheels while following this trajectory. The experiments show that the Dubins path can be calculated quickly and well smoothed.
Text to speech (TTS), or speech synthesis, which aims to synthesize intelligible and natural speech given text, is a hot research topic in speech, language, and machine learning communities and has broad applications in the industry. As the development of deep learning and artificial intelligence, neural network-based TTS has significantly improved the quality of synthesized speech in recent years. In this paper, we conduct a comprehensive survey on neural TTS, aiming to provide a good understanding of current research and future trends. We focus on the key components in neural TTS, including text analysis, acoustic models and vocoders, and several advanced topics, including fast TTS, low-resource TTS, robust TTS, expressive TTS, and adaptive TTS, etc. We further summarize resources related to TTS (e.g., datasets, opensource implementations) and discuss future research directions. This survey can serve both academic researchers and industry practitioners working on TTS.
It has been shown that deep neural networks are prone to overfitting on biased training data. Towards addressing this issue, meta-learning employs a meta model for correcting the training bias. Despite the promising performances, super slow training is currently the bottleneck in the meta learning approaches. In this paper, we introduce a novel Faster Meta Update Strategy (FaMUS) to replace the most expensive step in the meta gradient computation with a faster layer-wise approximation. We empirically find that FaMUS yields not only a reasonably accurate but also a low-variance approximation of the meta gradient. We conduct extensive experiments to verify the proposed method on two tasks. We show our method is able to save two-thirds of the training time while still maintaining the comparable or achieving even better generalization performance. In particular, our method achieves the state-of-the-art performance on both synthetic and realistic noisy labels, and obtains promising performance on long-tailed recognition on standard benchmarks.
Relation prediction for knowledge graphs aims at predicting missing relationships between entities. Despite the importance of inductive relation prediction, most previous works are limited to a transductive setting and cannot process previously unseen entities. The recent proposed subgraph-based relation reasoning models provided alternatives to predict links from the subgraph structure surrounding a candidate triplet inductively. However, we observe that these methods often neglect the directed nature of the extracted subgraph and weaken the role of relation information in the subgraph modeling. As a result, they fail to effectively handle the asymmetric/anti-symmetric triplets and produce insufficient embeddings for the target triplets. To this end, we introduce a \textbf{C}\textbf{o}mmunicative \textbf{M}essage \textbf{P}assing neural network for \textbf{I}nductive re\textbf{L}ation r\textbf{E}asoning, \textbf{CoMPILE}, that reasons over local directed subgraph structures and has a vigorous inductive bias to process entity-independent semantic relations. In contrast to existing models, CoMPILE strengthens the message interactions between edges and entitles through a communicative kernel and enables a sufficient flow of relation information. Moreover, we demonstrate that CoMPILE can naturally handle asymmetric/anti-symmetric relations without the need for explosively increasing the number of model parameters by extracting the directed enclosing subgraphs. Extensive experiments show substantial performance gains in comparison to state-of-the-art methods on commonly used benchmark datasets with variant inductive settings.