In the wake of the post-pandemic era, marked by social isolation and surging rates of depression and anxiety, conversational agents based on digital psychotherapy can play an influential role compared to traditional therapy sessions. In this work, we develop a voice-capable chatbot in Farsi to guide users through Self-Attachment (SAT), a novel, self-administered, holistic psychological technique based on attachment theory. Our chatbot uses a dynamic array of rule-based and classification-based modules to comprehend user input throughout the conversation and navigates a dialogue flowchart accordingly, recommending appropriate SAT exercises that depend on the user's emotional and mental state. In particular, we collect a dataset of over 6,000 utterances and develop a novel sentiment-analysis module that classifies user sentiment into 12 classes, with accuracy above 92%. To keep the conversation novel and engaging, the chatbot's responses are retrieved from a large dataset of utterances created with the aid of Farsi GPT-2 and a reinforcement learning approach, thus requiring minimal human annotation. Our chatbot also offers a question-answering module, called SAT Teacher, to answer users' questions about the principles of Self-Attachment. Finally, we design a cross-platform application as the bot's user interface. We evaluate our platform in a ten-day human study with N=52 volunteers from the non-clinical population, who have had over 2,000 dialogues in total with the chatbot. The results indicate that the platform was engaging to most users (75%), 72% felt better after the interactions, and 74% were satisfied with the SAT Teacher's performance.
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Approximation theory plays a central role in numerical analysis, undergoing continuous evolution through a spectrum of methodologies. Notably, Lebesgue, Weierstrass, Fourier, and Chebyshev approximations stand out among these methods. However, each technique possesses inherent limitations, underscoring the critical importance of selecting an appropriate approximation method tailored to specific problem domains. This article delves into the utilization of Chebyshev polynomials at Chebyshev nodes for approximation. For sufficiently smooth functions, the partial sum of Chebyshev series expansion offers optimal polynomial approximation, rendering it a preferred choice in various applications such as digital signal processing and graph filters due to its computational efficiency. In this article, we focus on functions of bounded variation, which find numerous applications across mathematical physics, hyperbolic conservations, and optimization. We present two optimal error estimations associated with Chebyshev polynomial approximations tailored for such functions. To validate our theoretical assertions, we conduct numerical experiments. Additionally, we delineate promising future avenues aligned with this research, particularly within the realms of machine learning and related fields.
Reconfigurable Intelligent Surface (RIS) modeling and optimization are a crucial steps in developing the next generation of wireless communications. To this aim, the availability of accurate electromagnetic (EM) models is of paramount important for the design of RIS-assisted communication links. In this work, we validate a widely-used analytical multiport network for RISs by means of a well-established full-wave numerical method based on the Partial Elements Equivalent Circuit (PEEC) approach. Numerical results show good agreement between the two methods, thus demonstrating i) the considered multiport network model being effective and ii) the PEEC method being appropriate for EM modeling of RIS-assisted wireless links.
The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an efficient gene-editing system requires a deep understanding of CRISPR technology, and the complex experimental systems under investigation. While Large Language Models (LLMs) have shown promise in various tasks, they often lack specific knowledge and struggle to accurately solve biological design problems. In this work, we introduce CRISPR-GPT, an LLM agent augmented with domain knowledge and external tools to automate and enhance the design process of CRISPR-based gene-editing experiments. CRISPR-GPT leverages the reasoning ability of LLMs to facilitate the process of selecting CRISPR systems, designing guide RNAs, recommending cellular delivery methods, drafting protocols, and designing validation experiments to confirm editing outcomes. We showcase the potential of CRISPR-GPT for assisting non-expert researchers with gene-editing experiments from scratch and validate the agent's effectiveness in a real-world use case. Furthermore, we explore the ethical and regulatory considerations associated with automated gene-editing design, highlighting the need for responsible and transparent use of these tools. Our work aims to bridge the gap between beginner biological researchers and CRISPR genome engineering techniques, and demonstrate the potential of LLM agents in facilitating complex biological discovery tasks.
In the evolving landscape of digital finance, the transition from centralized to decentralized trust mechanisms, primarily driven by blockchain technology, plays a critical role in shaping the cryptocurrency ecosystem. This paradigm shift raises questions about the traditional reliance on centralized trust and introduces a novel, decentralized trust framework built upon distributed networks. Our research delves into the consequences of this shift, particularly focusing on how incidents influence trust within cryptocurrency markets, thereby affecting trade behaviors in centralized (CEXs) and decentralized exchanges (DEXs). We conduct a comprehensive analysis of various events, assessing their effects on market dynamics, including token valuation and trading volumes in both CEXs and DEXs. Our findings highlight the pivotal role of trust in directing user preferences and the fluidity of trust transfer between centralized and decentralized platforms. Despite certain anomalies, the results largely align with our initial hypotheses, revealing the intricate nature of user trust in cryptocurrency markets. This study contributes significantly to interdisciplinary research, bridging distributed systems, behavioral finance, and Decentralized Finance (DeFi). It offers valuable insights for the distributed computing community, particularly in understanding and applying distributed trust mechanisms in digital economies, paving the way for future research that could further explore the socio-economic dimensions and leverage blockchain data in this dynamic domain.
Social anxiety represents a prevalent challenge in modern society, affecting individuals across personal and professional spheres. Left unaddressed, this condition can yield substantial negative consequences, impacting social interactions and performance. Further understanding its diverse physical and emotional symptoms becomes pivotal for comprehensive diagnosis and tailored therapeutic interventions. This study analyze prevalence and frequency of social anxiety symptoms taken from Mayo Clinic, exploring diverse human experiences from utilizing a large Reddit dataset dedicated to this issue. Leveraging these platforms, the research aims to extract insights and examine a spectrum of physical and emotional symptoms linked to social anxiety disorder. Upholding ethical considerations, the study maintains strict user anonymity within the dataset. By employing a novel approach, the research utilizes BART-based multi-label zero-shot classification to identify and measure symptom prevalence and significance in the form of probability score for each symptom under consideration. Results uncover distinctive patterns: "Trembling" emerges as a prevalent physical symptom, while emotional symptoms like "Fear of being judged negatively" exhibit high frequencies. These findings offer insights into the multifaceted nature of social anxiety, aiding clinical practices and interventions tailored to its diverse expressions.
We investigate the role of various demonstration components in the in-context learning (ICL) performance of large language models (LLMs). Specifically, we explore the impacts of ground-truth labels, input distribution, and complementary explanations, particularly when these are altered or perturbed. We build on previous work, which offers mixed findings on how these elements influence ICL. To probe these questions, we employ explainable NLP (XNLP) methods and utilize saliency maps of contrastive demonstrations for both qualitative and quantitative analysis. Our findings reveal that flipping ground-truth labels significantly affects the saliency, though it's more noticeable in larger LLMs. Our analysis of the input distribution at a granular level reveals that changing sentiment-indicative terms in a sentiment analysis task to neutral ones does not have as substantial an impact as altering ground-truth labels. Finally, we find that the effectiveness of complementary explanations in boosting ICL performance is task-dependent, with limited benefits seen in sentiment analysis tasks compared to symbolic reasoning tasks. These insights are critical for understanding the functionality of LLMs and guiding the development of effective demonstrations, which is increasingly relevant in light of the growing use of LLMs in applications such as ChatGPT. Our research code is publicly available at //github.com/paihengxu/XICL.
Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for risk surveillance and diagnosis often lack adequate interpretability, fairness, and reproducibility. To address this, we proposed an Explainable AI (XAI) framework designed to answer five critical questions: why, why not, how, what if, and what else, with the goal of enhancing the explainability and transparency of AI models. We incorporated various techniques such as Local Interpretable Model-agnostic Explanations (LIME), SHapley Additive exPlanations (SHAP), counterfactual explanations, model cards, an interactive feature manipulation interface, and the identification of similar patients to address these questions. We showcased an XAI interface prototype that adheres to this framework for predicting major postoperative complications. This initial implementation has provided valuable insights into the vast explanatory potential of our XAI framework and represents an initial step towards its clinical adoption.
This article presents the affordances that Generative Artificial Intelligence can have in disinformation context, one of the major threats to our digitalized society. We present a research framework to generate customized agent-based social networks for disinformation simulations that would enable understanding and evaluation of the phenomena whilst discussing open challenges.
The rapid development of deep learning has made a great progress in segmentation, one of the fundamental tasks of computer vision. However, the current segmentation algorithms mostly rely on the availability of pixel-level annotations, which are often expensive, tedious, and laborious. To alleviate this burden, the past years have witnessed an increasing attention in building label-efficient, deep-learning-based segmentation algorithms. This paper offers a comprehensive review on label-efficient segmentation methods. To this end, we first develop a taxonomy to organize these methods according to the supervision provided by different types of weak labels (including no supervision, coarse supervision, incomplete supervision and noisy supervision) and supplemented by the types of segmentation problems (including semantic segmentation, instance segmentation and panoptic segmentation). Next, we summarize the existing label-efficient segmentation methods from a unified perspective that discusses an important question: how to bridge the gap between weak supervision and dense prediction -- the current methods are mostly based on heuristic priors, such as cross-pixel similarity, cross-label constraint, cross-view consistency, cross-image relation, etc. Finally, we share our opinions about the future research directions for label-efficient deep segmentation.
Many tasks in natural language processing can be viewed as multi-label classification problems. However, most of the existing models are trained with the standard cross-entropy loss function and use a fixed prediction policy (e.g., a threshold of 0.5) for all the labels, which completely ignores the complexity and dependencies among different labels. In this paper, we propose a meta-learning method to capture these complex label dependencies. More specifically, our method utilizes a meta-learner to jointly learn the training policies and prediction policies for different labels. The training policies are then used to train the classifier with the cross-entropy loss function, and the prediction policies are further implemented for prediction. Experimental results on fine-grained entity typing and text classification demonstrate that our proposed method can obtain more accurate multi-label classification results.
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