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Designs for screening experiments usually include factors with two levels only. Adding a few four-level factors allows for the inclusion of multi-level categorical factors or quantitative factors with possible quadratic or third-order effects. Three examples motivated us to generate a large catalog of designs with two-level factors as well as four-level factors. To create the catalog, we considered three methods. In the first method, we select designs using a search table, and in the second method, we use a procedure that selects candidate designs based on the properties of their projections into fewer factors. The third method is actually a benchmark method, in which we use a general orthogonal array enumeration algorithm. We compare the efficiencies of the new methods for generating complete sets of non-isomorphic designs. Finally, we use the most efficient method to generate a catalog of designs with up to three four-level factors and up to 20 two-level factors for run sizes 16, 32, 64, and 128. In some cases, a complete enumeration was infeasible. For these cases, we used a bounded enumeration strategy instead. We demonstrate the usefulness of the catalog by revisiting the motivating examples.

Fine-grained supervision based on object annotations has been widely used for vision and language pre-training (VLP). However, in real-world application scenarios, aligned multi-modal data is usually in the image-caption format, which only provides coarse-grained supervision. It is cost-expensive to collect object annotations and build object annotation pre-extractor for different scenarios. In this paper, we propose a fine-grained self-supervision signal without object annotations from a replacement perspective. First, we propose a homonym sentence rewriting (HSR) algorithm to provide token-level supervision. The algorithm replaces a verb/noun/adjective/quantifier word of the caption with its homonyms from WordNet. Correspondingly, we propose a replacement vision-language modeling (RVLM) framework to exploit the token-level supervision. Two replaced modeling tasks, i.e., replaced language contrastive (RLC) and replaced language modeling (RLM), are proposed to learn the fine-grained alignment. Extensive experiments on several downstream tasks demonstrate the superior performance of the proposed method.

Video retrieval is becoming increasingly important owing to the rapid emergence of videos on the Internet. The dominant paradigm for video retrieval learns video-text representations by pushing the distance between the similarity of positive pairs and that of negative pairs apart from a fixed margin. However, negative pairs used for training are sampled randomly, which indicates that the semantics between negative pairs may be related or even equivalent, while most methods still enforce dissimilar representations to decrease their similarity. This phenomenon leads to inaccurate supervision and poor performance in learning video-text representations. While most video retrieval methods overlook that phenomenon, we propose an adaptive margin changed with the distance between positive and negative pairs to solve the aforementioned issue. First, we design the calculation framework of the adaptive margin, including the method of distance measurement and the function between the distance and the margin. Then, we explore a novel implementation called "Cross-Modal Generalized Self-Distillation" (CMGSD), which can be built on the top of most video retrieval models with few modifications. Notably, CMGSD adds few computational overheads at train time and adds no computational overhead at test time. Experimental results on three widely used datasets demonstrate that the proposed method can yield significantly better performance than the corresponding backbone model, and it outperforms state-of-the-art methods by a large margin.

Training a 3D scene understanding model requires complicated human annotations, which are laborious to collect and result in a model only encoding close-set object semantics. In contrast, vision-language pre-training models (e.g., CLIP) have shown remarkable open-world reasoning properties. To this end, we propose directly transferring CLIP's feature space to 3D scene understanding model without any form of supervision. We first modify CLIP's input and forwarding process so that it can be adapted to extract dense pixel features for 3D scene contents. We then project multi-view image features to the point cloud and train a 3D scene understanding model with feature distillation. Without any annotations or additional training, our model achieves promising annotation-free semantic segmentation results on open-vocabulary semantics and long-tailed concepts. Besides, serving as a cross-modal pre-training framework, our method can be used to improve data efficiency during fine-tuning. Our model outperforms previous SOTA methods in various zero-shot and data-efficient learning benchmarks. Most importantly, our model successfully inherits CLIP's rich-structured knowledge, allowing 3D scene understanding models to recognize not only object concepts but also open-world semantics.

For robot manipulation, a complete and accurate object shape is desirable. Here, we present a method that combines visual and haptic reconstruction in a closed-loop pipeline. From an initial viewpoint, the object shape is reconstructed using an implicit surface deep neural network. The location with highest uncertainty is selected for haptic exploration, the object is touched, the new information from touch and a new point cloud from the camera are added, object position is re-estimated and the cycle is repeated. We extend Rustler et al. (2022) by using a new theoretically grounded method to determine the points with highest uncertainty, and we increase the yield of every haptic exploration by adding not only the contact points to the point cloud but also incorporating the empty space established through the robot movement to the object. Additionally, the solution is compact in that the jaws of a closed two-finger gripper are directly used for exploration. The object position is re-estimated after every robot action and multiple objects can be present simultaneously on the table. We achieve a steady improvement with every touch using three different metrics and demonstrate the utility of the better shape reconstruction in grasping experiments on the real robot. On average, grasp success rate increases from 63.3% to 70.4% after a single exploratory touch and to 82.7% after five touches. The collected data and code are publicly available (//osf.io/j6rkd/, //github.com/ctu-vras/vishac)

We study the problem of extrapolative controlled generation, i.e., generating sequences with attribute values beyond the range seen in training. This task is of significant importance in automated design, especially drug discovery, where the goal is to design novel proteins that are \textit{better} (e.g., more stable) than existing sequences. Thus, by definition, the target sequences and their attribute values are out of the training distribution, posing challenges to existing methods that aim to directly generate the target sequence. Instead, in this work, we propose Iterative Controlled Extrapolation (ICE) which iteratively makes local edits to a sequence to enable extrapolation. We train the model on synthetically generated sequence pairs that demonstrate small improvement in the attribute value. Results on one natural language task (sentiment analysis) and two protein engineering tasks (ACE2 stability and AAV fitness) show that ICE considerably outperforms state-of-the-art approaches despite its simplicity. Our code and models are available at: //github.com/vishakhpk/iter-extrapolation.

Temporal relational modeling in video is essential for human action understanding, such as action recognition and action segmentation. Although Graph Convolution Networks (GCNs) have shown promising advantages in relation reasoning on many tasks, it is still a challenge to apply graph convolution networks on long video sequences effectively. The main reason is that large number of nodes (i.e., video frames) makes GCNs hard to capture and model temporal relations in videos. To tackle this problem, in this paper, we introduce an effective GCN module, Dilated Temporal Graph Reasoning Module (DTGRM), designed to model temporal relations and dependencies between video frames at various time spans. In particular, we capture and model temporal relations via constructing multi-level dilated temporal graphs where the nodes represent frames from different moments in video. Moreover, to enhance temporal reasoning ability of the proposed model, an auxiliary self-supervised task is proposed to encourage the dilated temporal graph reasoning module to find and correct wrong temporal relations in videos. Our DTGRM model outperforms state-of-the-art action segmentation models on three challenging datasets: 50Salads, Georgia Tech Egocentric Activities (GTEA), and the Breakfast dataset. The code is available at //github.com/redwang/DTGRM.

In this paper, we adopt 3D Convolutional Neural Networks to segment volumetric medical images. Although deep neural networks have been proven to be very effective on many 2D vision tasks, it is still challenging to apply them to 3D tasks due to the limited amount of annotated 3D data and limited computational resources. We propose a novel 3D-based coarse-to-fine framework to effectively and efficiently tackle these challenges. The proposed 3D-based framework outperforms the 2D counterpart to a large margin since it can leverage the rich spatial infor- mation along all three axes. We conduct experiments on two datasets which include healthy and pathological pancreases respectively, and achieve the current state-of-the-art in terms of Dice-S{\o}rensen Coefficient (DSC). On the NIH pancreas segmentation dataset, we outperform the previous best by an average of over 2%, and the worst case is improved by 7% to reach almost 70%, which indicates the reliability of our framework in clinical applications.

Person Re-identification (re-id) faces two major challenges: the lack of cross-view paired training data and learning discriminative identity-sensitive and view-invariant features in the presence of large pose variations. In this work, we address both problems by proposing a novel deep person image generation model for synthesizing realistic person images conditional on pose. The model is based on a generative adversarial network (GAN) and used specifically for pose normalization in re-id, thus termed pose-normalization GAN (PN-GAN). With the synthesized images, we can learn a new type of deep re-id feature free of the influence of pose variations. We show that this feature is strong on its own and highly complementary to features learned with the original images. Importantly, we now have a model that generalizes to any new re-id dataset without the need for collecting any training data for model fine-tuning, thus making a deep re-id model truly scalable. Extensive experiments on five benchmarks show that our model outperforms the state-of-the-art models, often significantly. In particular, the features learned on Market-1501 can achieve a Rank-1 accuracy of 68.67% on VIPeR without any model fine-tuning, beating almost all existing models fine-tuned on the dataset.

Recurrent neural nets (RNN) and convolutional neural nets (CNN) are widely used on NLP tasks to capture the long-term and local dependencies, respectively. Attention mechanisms have recently attracted enormous interest due to their highly parallelizable computation, significantly less training time, and flexibility in modeling dependencies. We propose a novel attention mechanism in which the attention between elements from input sequence(s) is directional and multi-dimensional (i.e., feature-wise). A light-weight neural net, "Directional Self-Attention Network (DiSAN)", is then proposed to learn sentence embedding, based solely on the proposed attention without any RNN/CNN structure. DiSAN is only composed of a directional self-attention with temporal order encoded, followed by a multi-dimensional attention that compresses the sequence into a vector representation. Despite its simple form, DiSAN outperforms complicated RNN models on both prediction quality and time efficiency. It achieves the best test accuracy among all sentence encoding methods and improves the most recent best result by 1.02% on the Stanford Natural Language Inference (SNLI) dataset, and shows state-of-the-art test accuracy on the Stanford Sentiment Treebank (SST), Multi-Genre natural language inference (MultiNLI), Sentences Involving Compositional Knowledge (SICK), Customer Review, MPQA, TREC question-type classification and Subjectivity (SUBJ) datasets.