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Lesion images are frequently taken in open-set settings. Because of this, the image data generated is extremely varied in nature.It is difficult for a convolutional neural network to find proper features and generalise well, as a result content based image retrieval (CBIR) system for lesion images are difficult to build. This paper explores this domain and proposes multiple similarity measures which uses Style Loss and Dice Coefficient via a novel similarity measure called I1-Score. Out of the CBIR similarity measures proposed, pure style loss approach achieves a remarkable accuracy increase over traditional approaches like Euclidean Distance and Cosine Similarity. The I1-Scores using style loss performed better than traditional approaches by a small margin, whereas, I1-Scores with dice-coefficient faired very poorly. The model used is trained using ensemble learning for better generalization.

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Image segmentation is a key topic in image processing and computer vision with applications such as scene understanding, medical image analysis, robotic perception, video surveillance, augmented reality, and image compression, among many others. Various algorithms for image segmentation have been developed in the literature. Recently, due to the success of deep learning models in a wide range of vision applications, there has been a substantial amount of works aimed at developing image segmentation approaches using deep learning models. In this survey, we provide a comprehensive review of the literature at the time of this writing, covering a broad spectrum of pioneering works for semantic and instance-level segmentation, including fully convolutional pixel-labeling networks, encoder-decoder architectures, multi-scale and pyramid based approaches, recurrent networks, visual attention models, and generative models in adversarial settings. We investigate the similarity, strengths and challenges of these deep learning models, examine the most widely used datasets, report performances, and discuss promising future research directions in this area.

In this paper, we aim to improve the performance of semantic image segmentation in a semi-supervised setting in which training is effectuated with a reduced set of annotated images and additional non-annotated images. We present a method based on an ensemble of deep segmentation models. Each model is trained on a subset of the annotated data, and uses the non-annotated images to exchange information with the other models, similar to co-training. Even if each model learns on the same non-annotated images, diversity is preserved with the use of adversarial samples. Our results show that this ability to simultaneously train models, which exchange knowledge while preserving diversity, leads to state-of-the-art results on two challenging medical image datasets.

Fast and scalable Content-Based Image Retrieval using visual features is required for document analysis, Medical image analysis, etc. in the present age. Convolutional Neural Network (CNN) activations as features achieved their outstanding performance in this area. Deep Convolutional representations using the softmax function in the output layer are also ones among visual features. However, almost all the image retrieval systems hold their index of visual features on main memory in order to high responsiveness, limiting their applicability for big data applications. In this paper, we propose a fast calculation method of cosine similarity with L2 norm indexed in advance on Elasticsearch. We evaluate our approach with ImageNet Dataset and VGG-16 pre-trained model. The evaluation results show the effectiveness and efficiency of our proposed method.

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own strengths and weaknesses, and by unifying them together, one may be able to achieve more accurate results. In this paper, we propose a new ensemble learning framework for 3D biomedical image segmentation that combines the merits of 2D and 3D models. First, we develop a fully convolutional network based meta-learner to learn how to improve the results from 2D and 3D models (base-learners). Then, to minimize over-fitting for our sophisticated meta-learner, we devise a new training method that uses the results of the base-learners as multiple versions of "ground truths". Furthermore, since our new meta-learner training scheme does not depend on manual annotation, it can utilize abundant unlabeled 3D image data to further improve the model. Extensive experiments on two public datasets (the HVSMR 2016 Challenge dataset and the mouse piriform cortex dataset) show that our approach is effective under fully-supervised, semi-supervised, and transductive settings, and attains superior performance over state-of-the-art image segmentation methods.

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate the problem, constrained image sizes and model complexities can lead to unnecessary increase in computational cost and decrease in performance. As many common morphological features are usually shared by different classification tasks of an organ, it is greatly beneficial if we can extract such features to improve classification with limited samples. Therefore, inspired by the idea of curriculum learning, we propose a strategy for building medical image classifiers using features from segmentation networks. By using a segmentation network pre-trained on similar data as the classification task, the machine can first learn the simpler shape and structural concepts before tackling the actual classification problem which usually involves more complicated concepts. Using our proposed framework on a 3D three-class brain tumor type classification problem, we achieved 82% accuracy on 191 testing samples with 91 training samples. When applying to a 2D nine-class cardiac semantic level classification problem, we achieved 86% accuracy on 263 testing samples with 108 training samples. Comparisons with ImageNet pre-trained classifiers and classifiers trained from scratch are presented.

Learning compact binary codes for image retrieval problem using deep neural networks has attracted increasing attention recently. However, training deep hashing networks is challenging due to the binary constraints on the hash codes, the similarity preserving property, and the requirement for a vast amount of labelled images. To the best of our knowledge, none of the existing methods has tackled all of these challenges completely in a unified framework. In this work, we propose a novel end-to-end deep hashing approach, which is trained to produce binary codes directly from image pixels without the need of manual annotation. In particular, we propose a novel pairwise binary constrained loss function, which simultaneously encodes the distances between pairs of hash codes, and the binary quantization error. In order to train the network with the proposed loss function, we also propose an efficient parameter learning algorithm. In addition, to provide similar/dissimilar training images to train the network, we exploit 3D models reconstructed from unlabelled images for automatic generation of enormous similar/dissimilar pairs. Extensive experiments on three image retrieval benchmark datasets demonstrate the superior performance of the proposed method over the state-of-the-art hashing methods on the image retrieval problem.

Deep Convolutional Neural Networks have pushed the state-of-the art for semantic segmentation provided that a large amount of images together with pixel-wise annotations is available. Data collection is expensive and a solution to alleviate it is to use transfer learning. This reduces the amount of annotated data required for the network training but it does not get rid of this heavy processing step. We propose a method of transfer learning without annotations on the target task for datasets with redundant content and distinct pixel distributions. Our method takes advantage of the approximate content alignment of the images between two datasets when the approximation error prevents the reuse of annotation from one dataset to another. Given the annotations for only one dataset, we train a first network in a supervised manner. This network autonomously learns to generate deep data representations relevant to the semantic segmentation. Then the images in the new dataset, we train a new network to generate a deep data representation that matches the one from the first network on the previous dataset. The training consists in a regression between feature maps and does not require any annotations on the new dataset. We show that this method reaches performances similar to a classic transfer learning on the PASCAL VOC dataset with synthetic transformations.

We propose a novel locally adaptive learning estimator for enhancing the inter- and intra- discriminative capabilities of Deep Neural Networks, which can be used as improved loss layer for semantic image segmentation tasks. Most loss layers compute pixel-wise cost between feature maps and ground truths, ignoring spatial layouts and interactions between neighboring pixels with same object category, and thus networks cannot be effectively sensitive to intra-class connections. Stride by stride, our method firstly conducts adaptive pooling filter operating over predicted feature maps, aiming to merge predicted distributions over a small group of neighboring pixels with same category, and then it computes cost between the merged distribution vector and their category label. Such design can make groups of neighboring predictions from same category involved into estimations on predicting correctness with respect to their category, and hence train networks to be more sensitive to regional connections between adjacent pixels based on their categories. In the experiments on Pascal VOC 2012 segmentation datasets, the consistently improved results show that our proposed approach achieves better segmentation masks against previous counterparts.

Recently, ensemble has been applied to deep metric learning to yield state-of-the-art results. Deep metric learning aims to learn deep neural networks for feature embeddings, distances of which satisfy given constraint. In deep metric learning, ensemble takes average of distances learned by multiple learners. As one important aspect of ensemble, the learners should be diverse in their feature embeddings. To this end, we propose an attention-based ensemble, which uses multiple attention masks, so that each learner can attend to different parts of the object. We also propose a divergence loss, which encourages diversity among the learners. The proposed method is applied to the standard benchmarks of deep metric learning and experimental results show that it outperforms the state-of-the-art methods by a significant margin on image retrieval tasks.

Hash coding has been widely used in the approximate nearest neighbor search for large-scale image retrieval. Recently, many deep hashing methods have been proposed and shown largely improved performance over traditional feature-learning-based methods. Most of these methods examine the pairwise similarity on the semantic-level labels, where the pairwise similarity is generally defined in a hard-assignment way. That is, the pairwise similarity is '1' if they share no less than one class label and '0' if they do not share any. However, such similarity definition cannot reflect the similarity ranking for pairwise images that hold multiple labels. In this paper, a new deep hashing method is proposed for multi-label image retrieval by re-defining the pairwise similarity into an instance similarity, where the instance similarity is quantified into a percentage based on the normalized semantic labels. Based on the instance similarity, a weighted cross-entropy loss and a minimum mean square error loss are tailored for loss-function construction, and are efficiently used for simultaneous feature learning and hash coding. Experiments on three popular datasets demonstrate that, the proposed method outperforms the competing methods and achieves the state-of-the-art performance in multi-label image retrieval.

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