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The multiple testing literature has primarily dealt with three types of dependence assumptions between p-values: independence, positive regression dependence, and arbitrary dependence. In this paper, we provide what we believe are the first theoretical results under various notions of negative dependence (negative Gaussian dependence, negative regression dependence, negative association, negative orthant dependence and weak negative dependence). These include the Simes global null test and the Benjamini-Hochberg procedure, which are known experimentally to be anti-conservative under negative dependence. The anti-conservativeness of these procedures is bounded by factors smaller than that under arbitrary dependence (in particular, by factors independent of the number of hypotheses tested). We also provide new results about negatively dependent e-values, and provide several examples as to when negative dependence may arise. Our proofs are elementary and short, thus arguably amenable to extensions and generalizations. We end with a few pressing open questions that we think our paper opens a door to solving.

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TalkBank is an online database that facilitates the sharing of linguistics research data. However, the existing TalkBank's API has limited data filtering and batch processing capabilities. To overcome these limitations, this paper introduces a pipeline framework that employs a hierarchical search approach, enabling efficient complex data selection. This approach involves a quick preliminary screening of relevant corpora that a researcher may need, and then perform an in-depth search for target data based on specific criteria. The identified files are then indexed, providing easier access for future analysis. Furthermore, the paper demonstrates how data from different studies curated with the framework can be integrated by standardizing and cleaning metadata, allowing researchers to extract insights from a large, integrated dataset. While being designed for TalkBank, the framework can also be adapted to process data from other open-science platforms.

Pruning deep neural networks is a widely used strategy to alleviate the computational burden in machine learning. Overwhelming empirical evidence suggests that pruned models retain very high accuracy even with a tiny fraction of parameters. However, relatively little work has gone into characterising the small pruned networks obtained, beyond a measure of their accuracy. In this paper, we use the sparse double descent approach to identify univocally and characterise pruned models associated with classification tasks. We observe empirically that, for a given task, iterative magnitude pruning (IMP) tends to converge to networks of comparable sizes even when starting from full networks with sizes ranging over orders of magnitude. We analyse the best pruned models in a controlled experimental setup and show that their number of parameters reflects task difficulty and that they are much better than full networks at capturing the true conditional probability distribution of the labels. On real data, we similarly observe that pruned models are less prone to overconfident predictions. Our results suggest that pruned models obtained via IMP not only have advantageous computational properties but also provide a better representation of uncertainty in learning.

Quantum adversarial machine learning is an emerging field that studies the vulnerability of quantum learning systems against adversarial perturbations and develops possible defense strategies. Quantum universal adversarial perturbations are small perturbations, which can make different input samples into adversarial examples that may deceive a given quantum classifier. This is a field that was rarely looked into but worthwhile investigating because universal perturbations might simplify malicious attacks to a large extent, causing unexpected devastation to quantum machine learning models. In this paper, we take a step forward and explore the quantum universal perturbations in the context of heterogeneous classification tasks. In particular, we find that quantum classifiers that achieve almost state-of-the-art accuracy on two different classification tasks can be both conclusively deceived by one carefully-crafted universal perturbation. This result is explicitly demonstrated with well-designed quantum continual learning models with elastic weight consolidation method to avoid catastrophic forgetting, as well as real-life heterogeneous datasets from hand-written digits and medical MRI images. Our results provide a simple and efficient way to generate universal perturbations on heterogeneous classification tasks and thus would provide valuable guidance for future quantum learning technologies.

In his seminal paper "Computing Machinery and Intelligence", Alan Turing introduced the "imitation game" as part of exploring the concept of machine intelligence. The Turing Test has since been the subject of much analysis, debate, refinement and extension. Here we sidestep the question of whether a particular machine can be labeled intelligent, or can be said to match human capabilities in a given context. Instead, but inspired by Turing, we draw attention to the seemingly simpler challenge of determining whether one is interacting with a human or with a machine, in the context of everyday life. We are interested in reflecting upon the importance of this Human-or-Machine question and the use one may make of a reliable answer thereto. Whereas Turing's original test is widely considered to be more of a thought experiment, the Human-or-Machine question as discussed here has obvious practical significance. And while the jury is still not in regarding the possibility of machines that can mimic human behavior with high fidelity in everyday contexts, we argue that near-term exploration of the issues raised here can contribute to development methods for computerized systems, and may also improve our understanding of human behavior in general.

The Pearson correlation coefficient is generally not invariant under common marginal transforms, but such an invariance property may hold true for specific models such as independence. A bivariate random vector is said to have an invariant correlation if its Pearson correlation coefficient remains unchanged under any common marginal transforms. We characterize all models of such a random vector via a certain combination of independence and the strongest positive dependence called comonotonicity. In particular, we show that the class of exchangeable copulas with invariant correlation is precisely described by what we call positive Fr\'echet copulas. We then extend the concept of invariant correlation to multi-dimensional models, and characterize the set of all invariant correlation matrices via the clique partition polytope. We also propose a positive regression dependent model which admits any prescribed invariant correlation matrix. Finally, all our characterization results of invariant correlation, except one special case, remain the same if the common marginal transforms are confined to the set of increasing ones.

We examine the problem of variance components testing in general mixed effects models using the likelihood ratio test. We account for the presence of nuisance parameters, i.e. the fact that some untested variances might also be equal to zero. Two main issues arise in this context leading to a non regular setting. First, under the null hypothesis the true parameter value lies on the boundary of the parameter space. Moreover, due to the presence of nuisance parameters the exact location of these boundary points is not known, which prevents from using classical asymptotic theory of maximum likelihood estimation. Then, in the specific context of nonlinear mixed-effects models, the Fisher information matrix is singular at the true parameter value. We address these two points by proposing a shrinked parametric bootstrap procedure, which is straightforward to apply even for nonlinear models. We show that the procedure is consistent, solving both the boundary and the singularity issues, and we provide a verifiable criterion for the applicability of our theoretical results. We show through a simulation study that, compared to the asymptotic approach, our procedure has a better small sample performance and is more robust to the presence of nuisance parameters. A real data application is also provided.

In epidemiological studies, participants' disease status is often collected through self-reported outcomes in place of formal medical tests due to budget constraints. However, self-reported outcomes are often subject to measurement errors, and may lead to biased estimates if used in statistical analyses. In this paper, we propose statistical methods to correct for outcome measurement errors in survival analyses with multiple failure types through a reweighting strategy. We also discuss asymptotic properties of the proposed estimators and derive their asymptotic variances. The work is motivated by Conservation of Hearing Study (CHEARS) which aims to evaluate risk factors for hearing loss in the Nurses' Health Studies II (NHS II). We apply the proposed method to adjust for the measurement errors in self-reported hearing outcomes; the analysis results suggest that tinnitus is positively associated with moderate hearing loss at both low or mid and high sound frequencies, while the effects between different frequencies are similar.

We study a mean change point testing problem for high-dimensional data, with exponentially- or polynomially-decaying tails. In each case, depending on the $\ell_0$-norm of the mean change vector, we separately consider dense and sparse regimes. We characterise the boundary between the dense and sparse regimes under the above two tail conditions for the first time in the change point literature and propose novel testing procedures that attain optimal rates in each of the four regimes up to a poly-iterated logarithmic factor. By comparing with previous results under Gaussian assumptions, our results quantify the costs of heavy-tailedness on the fundamental difficulty of change point testing problems for high-dimensional data. To be specific, when the error vectors follow sub-Weibull distributions, a CUSUM-type statistic is shown to achieve a minimax testing rate up to $\sqrt{\log\log(8n)}$. When the error distributions have polynomially-decaying tails, admitting bounded $\alpha$-th moments for some $\alpha \geq 4$, we introduce a median-of-means-type test statistic that achieves a near-optimal testing rate in both dense and sparse regimes. In particular, in the sparse regime, we further propose a computationally-efficient test to achieve the exact optimality. Surprisingly, our investigation in the even more challenging case of $2 \leq \alpha < 4$, unveils a new phenomenon that the minimax testing rate has no sparse regime, i.e.\ testing sparse changes is information-theoretically as hard as testing dense changes. This phenomenon implies a phase transition of the minimax testing rates at $\alpha = 4$.

We consider Shor's quantum factoring algorithm in the setting of noisy quantum gates. Under a generic model of random noise for (controlled) rotation gates, we prove that the algorithm does not factor integers of the form $pq$ when the noise exceeds a vanishingly small level in terms of $n$ -- the number of bits of the integer to be factored, where $p$ and $q$ are from a well-defined set of primes of positive density. We further prove that with probability $1 - o(1)$ over random prime pairs $(p,q)$, Shor's factoring algorithm does not factor numbers of the form $pq$, with the same level of random noise present.

Image segmentation is an important component of many image understanding systems. It aims to group pixels in a spatially and perceptually coherent manner. Typically, these algorithms have a collection of parameters that control the degree of over-segmentation produced. It still remains a challenge to properly select such parameters for human-like perceptual grouping. In this work, we exploit the diversity of segments produced by different choices of parameters. We scan the segmentation parameter space and generate a collection of image segmentation hypotheses (from highly over-segmented to under-segmented). These are fed into a cost minimization framework that produces the final segmentation by selecting segments that: (1) better describe the natural contours of the image, and (2) are more stable and persistent among all the segmentation hypotheses. We compare our algorithm's performance with state-of-the-art algorithms, showing that we can achieve improved results. We also show that our framework is robust to the choice of segmentation kernel that produces the initial set of hypotheses.

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