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In observational studies, covariates with substantial missing data are often omitted, despite their strong predictive capabilities. These excluded covariates are generally believed not to simultaneously affect both treatment and outcome, indicating that they are not genuine confounders and do not impact the identification of the average treatment effect (ATE). In this paper, we introduce an alternative doubly robust (DR) estimator that fully leverages non-confounding predictive covariates to enhance efficiency, while also allowing missing values in such covariates. Beyond the double robustness property, our proposed estimator is designed to be more efficient than the standard DR estimator. Specifically, when the propensity score model is correctly specified, it achieves the smallest asymptotic variance among the class of DR estimators, and brings additional efficiency gains by further integrating predictive covariates. Simulation studies demonstrate the notable performance of the proposed estimator over current popular methods. An illustrative example is provided to assess the effectiveness of right heart catheterization (RHC) for critically ill patients.

Vessel segmentation and centerline extraction are two crucial preliminary tasks for many computer-aided diagnosis tools dealing with vascular diseases. Recently, deep-learning based methods have been widely applied to these tasks. However, classic deep-learning approaches struggle to capture the complex geometry and specific topology of vascular networks, which is of the utmost importance in most applications. To overcome these limitations, the clDice loss, a topological loss that focuses on the vessel centerlines, has been recently proposed. This loss requires computing, with a proposed soft-skeleton algorithm, the skeletons of both the ground truth and the predicted segmentation. However, the soft-skeleton algorithm provides suboptimal results on 3D images, which makes the clDice hardly suitable on 3D images. In this paper, we propose to replace the soft-skeleton algorithm by a U-Net which computes the vascular skeleton directly from the segmentation. We show that our method provides more accurate skeletons than the soft-skeleton algorithm. We then build upon this network a cascaded U-Net trained with the clDice loss to embed topological constraints during the segmentation. The resulting model is able to predict both the vessel segmentation and centerlines with a more accurate topology.

Laminated glass achieves improved post-critical response through the composite effect of stiff glass layers and more compliant polymer films, manifested in progressive layer failure by multiple localized cracks. As a result, laminated glass exhibits greater ductility than non-laminated glass, making structures made with it suitable for safety-critical applications while maintaining their aesthetic qualities. However, such post-critical response is challenging to reproduce using deterministic failure models, which mostly predict failure through a single through-thickness crack localized simultaneously in all layers. This numerical-experimental study explores the extent to which progressive failure can be predicted by a simple randomized model, where layer-wise tensile strength is modeled by independent, identically distributed Weibull variables. On the numerical side, we employ a computationally efficient, dimensionally-reduced phase field formulation -- with each layer considered to be a Timoshenko beam -- to study progressive failure through combinatorial analysis and detailed Monte Carlo simulations. The reference experimental data were obtained from displacement-controlled four-point bending tests performed on multi-layer laminated glass beams. For certain combinations of the glass layer strengths, results show that the randomized model can reproduce progressive structural failure and the formation of multiple localized cracks in the glass layers. However, the predicted response was less ductile than that observed in experiments, and the model could not reproduce the most frequent glass layer failure sequence. These findings highlight the need to consider strength variability along the length of a beam and to include it in phase-field formulations.

In this work, we analyze a sublinear-time algorithm for selecting a few rows and columns of a matrix for low-rank approximation purposes. The algorithm is based on an initial uniformly random selection of rows and columns, followed by a refinement of this choice using a strong rank-revealing QR factorization. We prove bounds on the error of the corresponding low-rank approximation (more precisely, the CUR approximation error) when the matrix is a perturbation of a low-rank matrix that can be factorized into the product of matrices with suitable incoherence and/or sparsity assumptions.

This paper focuses on coordinating a robot swarm orbiting a convex path without collisions among the individuals. The individual robots lack braking capabilities and can only adjust their courses while maintaining their constant but different speeds. Instead of controlling the spatial relations between the robots, our formation control algorithm aims to deploy a dense robot swarm that mimics the behavior of tornado schooling fish. To achieve this objective safely, we employ a combination of a scalable overtaking rule, a guiding vector field, and a control barrier function with an adaptive radius to facilitate smooth overtakes. The decision-making process of the robots is distributed, relying only on local information. Practical applications include defensive structures or escorting missions with the added resiliency of a swarm without a centralized command. We provide a rigorous analysis of the proposed strategy and validate its effectiveness through numerical simulations involving a high density of unicycles.

In this study, we systematically evaluate the impact of common design choices in Mixture of Experts (MoEs) on validation performance, uncovering distinct influences at token and sequence levels. We also present empirical evidence showing comparable performance between a learned router and a frozen, randomly initialized router, suggesting that learned routing may not be essential. Our study further reveals that Sequence-level routing can result in topic-specific weak expert specialization, in contrast to syntax specialization observed with Token-level routing.

In this work, we address parametric non-stationary fluid dynamics problems within a model order reduction setting based on domain decomposition. Starting from the optimisation-based domain decomposition approach, we derive an optimal control problem, for which we present a convergence analysis in the case of non-stationary incompressible Navier-Stokes equations. We discretize the problem with the finite element method and we compare different model order reduction techniques: POD-Galerkin and a non-intrusive neural network procedure. We show that the classical POD-Galerkin is more robust and accurate also in transient areas, while the neural network can obtain simulations very quickly though being less precise in the presence of discontinuities in time or parameter domain. We test the proposed methodologies on two fluid dynamics benchmarks with physical parameters and time dependency: the non-stationary backward-facing step and lid-driven cavity flow.

Deep neural network based recommendation systems have achieved great success as information filtering techniques in recent years. However, since model training from scratch requires sufficient data, deep learning-based recommendation methods still face the bottlenecks of insufficient data and computational inefficiency. Meta-learning, as an emerging paradigm that learns to improve the learning efficiency and generalization ability of algorithms, has shown its strength in tackling the data sparsity issue. Recently, a growing number of studies on deep meta-learning based recommenddation systems have emerged for improving the performance under recommendation scenarios where available data is limited, e.g. user cold-start and item cold-start. Therefore, this survey provides a timely and comprehensive overview of current deep meta-learning based recommendation methods. Specifically, we propose a taxonomy to discuss existing methods according to recommendation scenarios, meta-learning techniques, and meta-knowledge representations, which could provide the design space for meta-learning based recommendation methods. For each recommendation scenario, we further discuss technical details about how existing methods apply meta-learning to improve the generalization ability of recommendation models. Finally, we also point out several limitations in current research and highlight some promising directions for future research in this area.

In large-scale systems there are fundamental challenges when centralised techniques are used for task allocation. The number of interactions is limited by resource constraints such as on computation, storage, and network communication. We can increase scalability by implementing the system as a distributed task-allocation system, sharing tasks across many agents. However, this also increases the resource cost of communications and synchronisation, and is difficult to scale. In this paper we present four algorithms to solve these problems. The combination of these algorithms enable each agent to improve their task allocation strategy through reinforcement learning, while changing how much they explore the system in response to how optimal they believe their current strategy is, given their past experience. We focus on distributed agent systems where the agents' behaviours are constrained by resource usage limits, limiting agents to local rather than system-wide knowledge. We evaluate these algorithms in a simulated environment where agents are given a task composed of multiple subtasks that must be allocated to other agents with differing capabilities, to then carry out those tasks. We also simulate real-life system effects such as networking instability. Our solution is shown to solve the task allocation problem to 6.7% of the theoretical optimal within the system configurations considered. It provides 5x better performance recovery over no-knowledge retention approaches when system connectivity is impacted, and is tested against systems up to 100 agents with less than a 9% impact on the algorithms' performance.

Recent advances in 3D fully convolutional networks (FCN) have made it feasible to produce dense voxel-wise predictions of volumetric images. In this work, we show that a multi-class 3D FCN trained on manually labeled CT scans of several anatomical structures (ranging from the large organs to thin vessels) can achieve competitive segmentation results, while avoiding the need for handcrafting features or training class-specific models. To this end, we propose a two-stage, coarse-to-fine approach that will first use a 3D FCN to roughly define a candidate region, which will then be used as input to a second 3D FCN. This reduces the number of voxels the second FCN has to classify to ~10% and allows it to focus on more detailed segmentation of the organs and vessels. We utilize training and validation sets consisting of 331 clinical CT images and test our models on a completely unseen data collection acquired at a different hospital that includes 150 CT scans, targeting three anatomical organs (liver, spleen, and pancreas). In challenging organs such as the pancreas, our cascaded approach improves the mean Dice score from 68.5 to 82.2%, achieving the highest reported average score on this dataset. We compare with a 2D FCN method on a separate dataset of 240 CT scans with 18 classes and achieve a significantly higher performance in small organs and vessels. Furthermore, we explore fine-tuning our models to different datasets. Our experiments illustrate the promise and robustness of current 3D FCN based semantic segmentation of medical images, achieving state-of-the-art results. Our code and trained models are available for download: //github.com/holgerroth/3Dunet_abdomen_cascade.